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Genetic Effects of Molecular Markers Related to Carcass Traits in Hanwoo Cattle (한우 도체형질 관련 분자표지의 유전적 효과)

  • Shin, Sung-Chul;Chung, Eui-Ryong
    • Journal of Life Science
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    • v.30 no.3
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    • pp.230-238
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    • 2020
  • Carcass traits are the most economically important traits in Hanwoo (Korean cattle). Recently, the development of the field of genomics has made it possible to identify DNA markers for the genetic evaluation of carcass and meat quality traits in beef cattle. The objective of this study was to assess the genetic effects of single nucleotide polymorphism (SNP) markers related to carcass traits by field evaluations in a commercial Hanwoo population. We evaluated 15 SNP markers (TG g.371T>C, APM1 g.1454G>A, FABP4 g.2834C>G, FABP4 g.3533T>A, FABP4 g.3691G>A, SCD g.10153A>G, SCD g.10329T >C, CPE g.601T>C, EDG1 g.166A>G, NPY g.4271T>C, GPD1 g.2766C>T, PDE1B g.17122A>G, PDE1B g.17507A>C, TNNT1 g.6650C>T, and RORC g.20152A>G) related to carcass traits in Hanwoo. Genotyping of these SNP markers was performed using PCR-RFLP analysis in Hanwoo steers (n = 1,536) to evaluate their association with carcass traits. Seven SNPs, APM1 g.1454G>, FABP4 g.3691G>A, SCD g.10153A>G, CPE g.601T>C, PDE1B g.17122A>G, TNNT1 g.6650C>T, and RORC g.20152A>G, were significantly associated with carcass traits such as marbling score (MS), backfat thickness (BF), musculus longissimus dorsi area (LDA), carcass weight (CW), meat grade (MG), meat color (MC), and maturity score (MA). The results suggest that these SNPs may be used as DNA markers for the selection of Hanwoo with higher meat quality.

Oral Concentrated Grape Juice Suppresses Expression of NF-kappa B, TNF-α and iNOS in Experimentally Induced Colorectal Carcinogenesis in Wistar Rats

  • de Lima Pazine Campanholo, Vanessa Maria;Silva, Roseane Mendes;Silva, Tiago Donizetti;Neto, Ricardo Artigiani;Paiotti, Ana Paula Ribeiro;Ribeiro, Daniel Araki;Forones, Nora Manoukian
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.3
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    • pp.947-952
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    • 2015
  • The aim of this study was to evaluate the effects of grape juice on colon carcinogenesis induced by azoxymethane (AOM) and expression of NF-kB, iNOS and TNF-${\alpha}$. Methods: Forty male Wistar rats were divided into 7 groups: G1, control; G2, 15 mg/kg AOM; G3, 1% grape juice 2 weeks before AOM; G4, 2% grape juice 2 weeks before AOM; G5, 1% grape juice 4 weeks after AOM; G6, 2% grape juice 4 weeks after AOM; G7, 2% grape juice without AOM. Histological changes and aberrant crypt foci (ACF) were studied, while RNA expression of NF-kB, TNF- and iNOS was evaluated by qPCR. Results: The number of ACF was higher in G2, and G4 presented a smaller number of crypts per focus than G5 (p=0.009) and G6. Small ACF (1-3) were more frequent in G4 compared to G2, G5 and G6 (p=0.009, p=0.009 and p=0.041, respectively). RNA expression of NF-kB was lower in G3 and G4 compared to G2 (p=0.004 and p=0.002, respectively). A positive correlation was observed between TNF-${\alpha}$ and NF-kB gene expression (p=0.002). In conclusion, the administration of 2% grape juice before AOM reduced the crypt multiplicity, attenuating carcinogenesis. Lower expression of NF-kB was observed in animals exposed to grape juice for a longer period of time, regardless of concentration.

Studies of Species and Distribution of Vesicular-Arbuscular Mycorrhizal Fungi in Relation to Salt-Marsh Plants (간석지(干潟地) 식물(植物)과 관련된Vesicular-Arbuscular Mycorrhizal Fungi의 분류(分類)와 분포(分布)에 관한 연구(硏究))

  • Koh, Seun-Duk;Lee, Hyung-Hoan
    • The Korean Journal of Mycology
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    • v.12 no.4
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    • pp.175-181
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    • 1984
  • Six species of Glomus and one species of Acaulospora of vesicular-arbuscular (VA) mycorrhizal fungi associated with four salt-marsh plants(Calamagrotis epigeios, Lotus corniculatus, Artemisia scoparia and Imperata cylindrica were isolated from salt-marsh soil. The six species of Glomus were identified as G. albidum(lst type), G. pulvinatum(2nd type), G. constrictium(3rd type), G. sp.(4th type), G. caledonicum(5th type), and G. sp. (6th type). The one species of Acaulospora was identified as A. scrobiculata(7th type). Three mycorrhizal fungi, G. albidum(l st type), G. pulvinatum(2nd type) and G. sp. (4th type) among the 7VA fungi were the most abundant types. The most common type of VA fungi occurred in rhizosphere soil from each plant was G. sp. (4th type) for Calamagrostis epigeios and Artemesia scoparia equally and G. pulvinatum for Lotus corniculatus and Imperata cylindrica equally.

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Therapeutic Effect of Lycii fructus Extract in Hepatotoxicity Induced by Carbon Tetrachloride (사염화탄소로 유발된 간손상에 대한 구기자 추출물의 치료효과)

  • Cho, Jung Hee;Sin, Ji Soon;Lee, Kwang Joo;Kim, Yun Bae;Kang, Jong Koo;Hwang, Seock Yeon
    • Korean Journal of Clinical Laboratory Science
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    • v.36 no.1
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    • pp.55-63
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    • 2004
  • The hepatotherapeutic effect of the extract of Lycii fructus has been studied in rats against $CCl_4$ induced liver toxicity. The rats were orally treated with $CCl_4$ (corn oil/$CCl_4$ 1:1, $1m{\ell}/kg$) and then $CCl_4$ ($0.5m{\ell}/kg$) administered four times for 2 weeks. The extracts of L. fructus have been administered every day for 2 weeks after the last $CCl_4$ injection. The experimental groups consisted of negative control (G1), positive control ($CCl_4$ alone; G2), extract of L. fructus (50 mg/kg; G3, 100 mg/kg; G4, 200 mg/kg; G5), respectively. There was a significant decrement to G2 on the serum level of aspartate aminotransferase, alanine aminotransferase, and alkaline phosphatase in G5. Also, the content of thiobarbituric acid reactive substance, and phosphatidylcholine hydroperxidase, a marker of lipid peroxidation, in the liver were decreased significantly G5 and G4 compared with G2. Although, catalase or superoxide dismutase, antioxidant enzyme, in the liver were decreased significantly too, it would not be a good sign for the liver. In histopathological findings, such a hepatocellular vacuolar degeneration, lobular restructure, cellular infiltration, necrosis, and so on were shown severely in G2. However, G4 and G5 was shown a mild cytoplasmic vacuolation and inflammatory cell. In conclusion, as a protection against cell damage, lipid peroxidation and serum level, it suggested that the extract of Lycii fructus would have been a therapeutic effect of liver injury directly.

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A Study of VoIP Encryption and Authentication Technologies in 4G WiBro Services (4G WiBro서비스에서 VoIP 암호화와 인증기술 연구)

  • Baek, Jong-Il;Chun, Woo-Sung;Park, Dea-Woo
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2011.10a
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    • pp.291-294
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    • 2011
  • 4G WiBro service in Korea, the world's fourth-generation communication is standardized. VoIP service has been activated one of the application in WiBro communications infrastructure. When using VoIP in the WiBro service, complementing the existing VoIP vulnerabilities in the encryption and authentication technology is a need for research. In this paper, fourth-generation WiBro, LTE, and the definition, 1G, 2G, 3G and 4G compares. And, WiBro service in the VoIP edaehan technical, administrative, physical, and hacker attacks and vulnerability analysis is the study of security measures. Enhanced security measures for the WiBro service to VoIP security through encryption and authentication technologies are studied.

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The Chromatic Number Algorithm in a Planar Graph (평면의 채색수 알고리즘)

  • Lee, Sang-Un
    • Journal of the Korea Society of Computer and Information
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    • v.19 no.5
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    • pp.19-25
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    • 2014
  • In this paper, I seek the chromatic number, the maximum number of colors necessary when adjoining vertices in the plane separated apart at the distance of 1 shall receive distinct colors. The upper limit of the chromatic number has been widely accepted as $4{\leq}{\chi}(G){\leq}7$ to which Hadwiger-Nelson proposed ${\chi}(G){\leq}7$ and Soifer ${\chi}(G){\leq}9$ I firstly propose an algorithm that obtains the minimum necessary chromatic number and show that ${\chi}(G)=3$ is attainable by determining the chromatic number for Hadwiger-Nelson's hexagonal graph. The proposed algorithm obtains a chromatic number of ${\chi}(G)=4$ assuming a Hadwiger-Nelson's hexagonal graph of 12 adjoining vertices, and again ${\chi}(G)=4$ for Soifer's square graph of 8 adjoining vertices. assert. Based on the results as such that this algorithm suggests the maximum chromatic number of a planar graph is ${\chi}(G)=4$ using simple assigned rule of polynomial time complexity to color for a vertex with minimum degree.

Studies on Saccharification and Citric Acid Fermentation of Alcoholic Distillery Waste(I) (주정증류 폐기물의 당화 및 구연산 발효에 관한 연구(I))

  • 서명교;서근학송승그
    • KSBB Journal
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    • v.5 no.4
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    • pp.383-390
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    • 1990
  • Alcoholic distillery waste was utilized as dual purposes to produce citric acid and to reduce the amount of waste to be treated. Enzyme and acid hydrolysis of this waste were studied to suggest effective way of present purpose. Enzymatic hydrolysis of this naked barley alcoholic distillery waste by $\alpha$-and $\beta$-amylase gave glucose as 8g/l concentration at $55^{\circ}C$ for 6 hours, which produced 1g/l citric acid and 5.33g/l mycelial. This waste material hydrolyzed with 25% HCl at $120^{\circ}C$ showed 21.5g/l glucose and produced 1.75g/l citric acid with 4.9g/1 mycelial. The glucose concentration was decreased to 3.44g/l by further 2nd acid hydrolysis because the monosugars were decomposed at prolonged hydrolysis conditions. The addition of 3g/l $NH_4NO_3$ increased the mycelial growth but reduced the amount of citric acid formed. The formation of citric acid was increased at low concentration of manganese ion.

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Analysis of Current 5G Open-Source Projects (공개 소프트웨어 기반 5G 프로젝트 개발 동향 분석)

  • Kim, M.J.;Park, K.M.;Park, J.G.;Kim, Y.S.;Lee, J.H.;Moon, D.S.
    • Electronics and Telecommunications Trends
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    • v.36 no.2
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    • pp.83-92
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    • 2021
  • 5G networks are rapidly expanding. Simultaneously, the need for a testbed-not a commercial network-is increasing to verify aspects such as 5G network security vulnerabilities. Open-source projects in 4G networks already exist and are implemented similarly in commercial networks. Due to the compatibilty between 5G and 4G networks, 5G networks are being developed and implemented as open-source projects on the basis of 4G networks. In this study, we review the development trends of 5G open-source projects and simulators that can be used for 5G research.

Trends and Analysis of 4G Wireless User Access Networks Issues (4G 무선가입자망 구축 동향 및 고도화 방안)

  • Hwang, Ho-Young;Hong, Jung-Wan;Kim, Seung-Cheon;Roh, Kwang-Hyun
    • The Journal of Society for e-Business Studies
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    • v.16 no.3
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    • pp.145-158
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    • 2011
  • Recently, the rapidly increased use of smartphone devices provides both opportunity and problems at the same time to the telecom companies in domestic and world wide. It provides a great opportunity to overcome the market stagnation of the existing voice- centric communications, and also problems of building a highly efficient new wireless access networks to accommodate huge volume of data traffic among smart devices. Facing with the age of keen competition, telecom companies have two kinds of strategies for network transition; a strategy of building uniform LTE -based 4G networks as fast as possible, and a hybrid network enhancement strategy compounding 3G and 4G networks using HSP A+, WiFi, cloud computing, etc. It is difficult to predict which strategy will have more successful outcome in the near future. This paper studies the trends and issues of network enhancement policies and transition strategies to the 4G network era, and tries to draw appropriate and efficient ways for network enhancement and operation.

New synthetic medium for growth of mycelium of Pleurotus species (느타리속(Pleurotus species) 균의 균사 배양을 위한 새로운 합성 배지)

  • Park, Won-Mok;Kim, Gyu-Hyun;Hyeon, Jae-Wook
    • The Korean Journal of Mycology
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    • v.23 no.3 s.74
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    • pp.275-283
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    • 1995
  • The nutritional requirements of mycelial growth for Pleurotus spp. were studied. As the carbon sources, soluble starch and dextrin, nitrogen sources, arginine and ammonium tartrate, and calcium sources, $CaCO_3$ enhanced mycelial growth. Optimum C/N ratio was 100 : 1. On the base of results from the experiment on nutritional requirements, the following receipe is suggested for growth of Pleurotus spp.; starch 15 g, arginine 3.484 g, ammonium tartrate 3.06 g, $CaCO_3$ 0.314 g, $KH_2PO_4$ 8.138 g, $K_2HPO_4$ 1.584 g, $MgSO_4{\cdot}7H_2O$ 1.5 g for P. sajor-caju and 2.5 g for P. ostreatus. $FeSO_4{\cdot}7H_2O$ 0.02 g, $ZnSO_4{\cdot}7H_2O$ 0.03 g, $MnSO_4{\cdot}7H_2O$ 0.02 g, optimum pH 6.0. This new synthetic medium is tentatively designated as Park's medium.

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