• Molecules and Cells
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• 제44권8호
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• pp.580-590
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• 2021

Patients with severe asthma have unmet clinical needs for effective and safe therapies. One possibility may be mesenchymal stem cell (MSC) therapy, which can improve asthma in murine models. However, it remains unclear how MSCs exert their beneficial effects in asthma. Here, we examined the effect of human umbilical cord blood-derived MSCs (hUC-MSC) on two mouse models of severe asthma, namely, Alternaria alternata-induced and house dust mite (HDM)/diesel exhaust particle (DEP)-induced asthma. hUC-MSC treatment attenuated lung type 2 (Th2 and type 2 innate lymphoid cell) inflammation in both models. However, these effects were only observed with particular treatment routes and timings. In vitro co-culture showed that hUC-MSC directly downregulated the interleukin (IL)-5 and IL-13 production of differentiated mouse Th2 cells and peripheral blood mononuclear cells from asthma patients. Thus, these results showed that hUC-MSC treatment can ameliorate asthma by suppressing the asthmogenic cytokine production of effector cells. However, the successful clinical application of MSCs in the future is likely to require careful optimization of the route, dosage, and timing.

• 한국융합학회논문지
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• 제13권3호
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• pp.265-274
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• 2022

본 연구는 2020년 1년간 수집된 심폐정지환자 세부상황표(2020년, 원시자료) 3,418건을 대상으로 하였다. 또한, 관련 법률과 지침을 조사하여 고찰하는 후향적 서술조사연구이다. 연구 결과, 첫째. '목격자에 의한 심폐소생술' 시행률 30.66%(1,047건)는 주목할 만한 결과로, 관련 법률 및 지침이 짜임새 있게 마련되어 있음을 짐작해 볼 수 있다. 둘째, '목격자에 의한 자동심장충격기 사용은 불과 0.10%(5건)에 불과한 것으로 나타났다. 이는 관련 법률 및 지침이 '구비 및 의무'에 다소 치우쳐 있기 때문으로 사료되며, 지역별 관련 대응 방법 모색의 전략적 차별성을 두어야 함을 시사한다. 셋째, 대구지역의 심정지 발생 장소는 가정이 71.97%(2,640건)로 나타났다. 향후 심정지 대응의 지역별 '맞춤전략' 및 '특별구급대'의 효율적 운영을 위하여, 원시데이터를 활용한 고급통계분석중심의 후속 연구가 필요하다.

• 한국치위생학회지
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• 제21권6호
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• pp.785-792
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• 2021

Objectives: Dental hygienists are an essential human resource in dental service organizations. However, there are several important persisting problems faced by them, that need to be solved. The purpose of this study was to explore the current situation in dental hygiene education institutions, number of active dental hygienists, and employment distribution across South Korea. Methods: The study gathered statistics of dental hygiene educational institutions, the ratio of active dental hygienists and the number of dental hygienists working across South Korea from officially reviewed websites. Results: Daegu and Gyeongbuk regions house the most number of colleges with dental hygiene programs. The Daejeon and Chungnam regions had the most universities with dental hygiene programs. The activity ratio of dental hygienists decreased every year. Dental hygienists' employment was highly focused in the Seoul and Gyeonggi provinces. Conclusions: The survey data can be used as basic data for future dental hygienist education to cope with the shortage of active dental hygienists and regional imbalances. This could prove useful to consider the employment of dental hygienists appropriately.

• 인간식물환경학회지
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• 제24권6호
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• pp.563-572
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• 2021

Background and objective: The ongoing COVID-19 pandemic restricted daily life, forcing people to spend time indoors. With the growing interest in mental health issues and residential environments, 'pet plants' have been receiving attention during the unprecedented social distancing measures. This study aims to analyze the change in trends of pet plants before and during the COVID-19 pandemic and provide basic data for studies related to pet plants and directions of future development. Methods: A total of 2,016 news articles using the keyword 'pet plants' were collected on Naver News from January 1, 2018 to August 15, 2019 (609 articles) and January 1, 2020 to August 15, 2021 (1,407 articles). The texts were tokenized into words using KoNLPy package, ultimately coming up with 63,597 words. The analyses included frequency of keywords and topic modeling based on Latent Dirichlet Allocation (LDA) to identify the inherent meanings of related words and each topic. Results: Topic modeling generated three topics in each period (before and during the COVID-19), and the results showed that pet plants in daily life have become the object of 'emotional support' and 'healing' during social distancing. In particular, pet plants, which had been distributed as a solution to prevent solitary deaths and depression among seniors living alone, are now expanded to help resolve the social isolation of the general public suffering from COVID-19. The new term 'plant butler' became a new trend, and there was a change in the trend in which people shared their hobbies and information about pet plants and communicated with others in online. Conclusion: Based on these findings, the trend data of pet plants before and after the outbreak of COVID-19 can provide the basis for activating research on pet plants and setting the direction for development of related industries considering the continuous popularity and trend of indoor gardening and green hobby.

• 한국인터넷방송통신학회논문지
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• 제22권4호
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• pp.133-139
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• 2022

최근 국내 축산 농가들에서는 생산성 향상을 위해 축사 환경 및 사양관리, 안전한 축산물 생산, 동물 복지 등에 데이터를 기반으로 한 기술이 도입되고 있다. 또한, 정부는 정책적으로 축산물의 생산성 향상 및 축산 환경을 개선하기 위해 ICT기반의 축사시설 현대화를 통한 스마트 축사 보급 사업을 2017년부터 진행하고 있다. 그러나 현재 스마트 축사는 모니터링과 제어의 연계성, 다양성, 통합성 등에서 한계가 있다. 그러므로 다양한 모니터링과 제어의 연계 및 통합을 하기 위해 지능화된 알고리즘 및 원격 제어로 축산의 모든 과정을 지능적으로 시스템화하기 위해서는 사물인터넷, 빅데이터, 인공지능, 클라우드 컴퓨팅, 모바일 등 지능정보기술을 기반으로 한 스마트 축산 시스템 개발이 필요하다. 본 연구에서는 지능정보기술 기반의 스마트 축사 관련 국내외 연구동향을 소개하고 첨단기술의 국내 적용 한계를 분석하였다. 끝으로 축산분야에 적용 가능한 미래 지능정보기술에 대해서 살펴보았다.

• 한국수소및신에너지학회논문집
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• 제34권4호
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• pp.334-341
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• 2023

The purity of hydrogen finally purified in the hydrogen purification process system is greatly influenced by the uniformity of the purification temperature of the dry tower. A in-house code that can be easily used by field designers has been developed to predict the capacity of the appropriate heat source and the time to reach the temperature of the dry tower. A code was developed to predict unsteady heat transfer using Visual Basic for Applications. To verify the developed code, a grid independence test was performed, and finally, calculations were performed for two cases. In the first case, the time for the temperature of the heater jacket to reach 360℃ was about 1,400 seconds when the supply heat source was 1,000 W. And in the second case, the time for the temperature of the heater jacket to reach 360℃ was about 710 seconds when the supply heat source was 2,000 W. It was confirmed that the developed code well describes the actual test data of the regeneration process of adsorption and desorption, and it is judged that the code developed in the design process of various capacity systems will be effectively applied to the heat capacity calculation in the future.

• Ocean Systems Engineering
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• 제13권2호
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• pp.173-193
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• 2023

Reliable prediction of the motion of FOWT (floating offshore wind turbine) and associated mooring line tension is important in both design and operation/monitoring processes. In the present study, a 5MW OC4 semisubmersible wind turbine is numerically modeled, simulated, and analyzed by the open-source numerical tool, OpenFAST and in-house numerical tool, Charm3D-FAST. Another commercial-level program FASTv8-OrcaFlex is also introduced for comparison for selected cases. The three simulation programs solve the same turbine-floater-mooring coupled dynamics in time domain while there exist minor differences in the details of the program. Both the motions and mooring-line tensions are calculated and compared with the DeepCWind 1/50 scale model-testing results. The system identification between the numerical and physical models is checked through the static-offset test and free-decay test. Then the system motions and mooring tensions are systematically compared among the simulated results and measured values. Reasonably good agreements between the simulation and measurement are demonstrated for (i) white-noise random waves, (ii) typical random waves, and (iii) typical random waves with steady wind. Based on the comparison between numerical results and experimental data, the relative importance and role of the differences in the numerical methodologies of those three programs can be observed and interpreted. These comparative-study results may provide a certain confidence level and some insight of potential variability in motion and tension predictions for future FOWT designs and applications.

• 한국산업보건학회지
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• 제33권4호
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• pp.464-470
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• 2023

Objectives: This study evaluated occupational exposures to noise and heat stress during routine non-outage works in three coal-fired power plants in the Republic of Korea. Methods: The data were collected during the summer of 2020. Full shift noise exposure of 52 workers were measured using noise dosimeters. Heat stress of 16 worksites were measured for 70 minutes using wet-bulb globe temperature monitors. Results: The noise dosimetry results revealed time-weighted averages that ranged from 47.5 to 88.9 dBA. 2 out of 52 noise measurements exceeded 85 dBA. Based on the arithmetic mean, the coal service group showed the highest level at 80.2 dBA by job tasks. Noise exposures exceeding 85 dBA were measured in the coal service and plant operator group. Heat stress index measurements ranged from 20.3℃ to 37.2℃. 1 out of 9 indices measured in coal facilities and 4 out of 7 indices measured in boiler house exceeded 1 hour TWA during moderate work. Heat stress indices measured from boiler houses were significantly higher than those measured from coal equipment. Conclusions: The results show that overexposure to noise and heat stress may be encountered during routine non-outage work activities in coal-fired power plants. Appropriate actions should be taken to reduce future health outcome from occupational exposure to noise and heat stress in the industry.

• 한국심리학회지 : 문화 및 사회문제
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• 제14권1호_spc
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• pp.255-272
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• 2008

세계적인 학교 폭력의 주요 현상인 집단따돌림에 대해 세계 여러 나라에서 이미 1970년대부터 연구가 이루어졌다. 이와 비교해 한국의 왕따 연구는 그 역사가 비교적 짧은 편이다. 본 연구에서는 외국의 불링(bullying)과는 달리 고유한 특성을 지니는 한국의 왕따에 대해 알아보았다. 한국의 왕따가 가지는 현상적 특성으로 집단성, 한 번 피해자가 되면 지속적인 괴롭힘에 노출되는 지속성, 가해자의 범위가 일반학생으로 확대되는 일반성이라 할 수 있다. 외부 환경적 특성으로 한국의 교육환경, 부정적인 가정환경, 집단주의 문화가 있다. 또한 왕따 현상에는 그 참여 역할이 중요한데 크게 세 가지의 구조 틀을 가진다. 즉 가해자, 피해자, 가해-피해자 중심의 구조, 가해자와 피해자를 제외한 중간집단(가해지지자, 방관자, 방어자)에 초점을 맞춘 구조, 마지막으로 가해자, 가해조력자, 가해강화자, 방어자, 피해자, 방관자의 참여역할 구조를 통해 각각의 역할에 따른 심리적 특성에 관한 연구결과를 설명하였다. 이러한 왕따의 특성을 반영하여, 전 학급을 대상으로 한 방관자 중심의 예방 프로그램과 그 효과에 관해 간략히 설명하고 앞으로의 방향에 대해 논의하였다.

• 한국음향학회지
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• 제42권6호
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• pp.627-636
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• 2023

코로나19 팬데믹으로 인해 전 세계 인구는 급격한 변화를 경험하였고, 이 중 하나가 재택근무의 증가였다. 앞으로도 언제든 감염병의 위험에 노출될 수 있으며, 이 외에도 여러 가지 배경으로 인해 재택근무의 확대가 예상된다. 이에 본 연구는 재택근무의 효율성을 제고하고 기존의 한계를 개선하기 위한 방안 마련을 위해 코로나19 팬데믹 시기 재택근무 경험자를 대상으로 실내 환경에 대한 인식을 조사하였다. 특별히 재택근무 경험자의 음환경 인식을 알아봄으로써 주택 내에서 근무할 때 경험하는 음환경 인식에는 어떠한 특성이 있으며, 응답자 개인의 어떠한 변수가 인식 변화에 영향을 주는지 알아보았다. 해당 조사를 통해 동거인 수, 방 개수와 주택 면적, 개인의 소음민감도에 따라 재택근무 시 외부소음, 이웃소음, 동거인소음을 인식하는 경향에 차이를 보이는 것을 확인하였다. 본 연구 결과는 향후 주거용도뿐만 아니라 업무 및 학습 용도로도 활용할 수 있는 다목적 주택 설계의 기반 자료로 활용될 수 있을 것이다.