• Progress in Medical Physics
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• v.14 no.1
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• pp.34-42
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• 2003

In medical imaging, three-dimensional (3D) display using Virtual Reality Modeling Language (VRML) as a portable file format can give intuitive information more efficiently on the World Wide Web (WWW). The web-based 3D visualization of functional images combined with anatomical images has not studied much in systematic ways. The goal of this study was to achieve a simultaneous observation of 3D anatomic and functional models with planar images on the WWW, providing their locational information in 3D space with a measuring implement using VRML. MRI and ictal-interictal SPECT images were obtained from one epileptic patient. Subtraction ictal SPECT co-registered to MRI (SISCOM) was performed to improve identification of a seizure focus. SISCOM image volumes were held by thresholds above one standard deviation (1-SD) and two standard deviations (2-SD). SISCOM foci and boundaries of gray matter, white matter, and cerebrospinal fluid (CSF) in the MRI volume were segmented and rendered to VRML polygonal surfaces by marching cube algorithm. Line profiles of x and y-axis that represent real lengths on an image were acquired and their maximum lengths were the same as 211.67 mm. The real size vs. the rendered VRML surface size was approximately the ratio of 1 to 605.9. A VRML measuring tool was made and merged with previous VRML surfaces. User interface tools were embedded with Java Script routines to display MRI planar images as cross sections of 3D surface models and to set transparencies of 3D surface models. When transparencies of 3D surface models were properly controlled, a fused display of the brain geometry with 3D distributions of focal activated regions provided intuitively spatial correlations among three 3D surface models. The epileptic seizure focus was in the right temporal lobe of the brain. The real position of the seizure focus could be verified by the VRML measuring tool and the anatomy corresponding to the seizure focus could be confirmed by MRI planar images crossing 3D surface models. The VRML application developed in this study may have several advantages. Firstly, 3D fused display and control of anatomic and functional image were achieved on the m. Secondly, the vector analysis of a 3D surface model was defined by the VRML measuring tool based on the real size. Finally, the anatomy corresponding to the seizure focus was intuitively detected by correlations with MRI images. Our web based visualization of 3-D fusion image and its localization will be a help to online research and education in diagnostic radiology, therapeutic radiology, and surgery applications.

• Korean Journal of Microbiology
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• v.54 no.4
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• pp.330-342
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• 2018

The Streptavidin and Biotin system has been studied most extensively as the high affinity non-covalent binding of Biotin to STR ($K_D=10^{-14}M$) and four Biotin binding sites in tetrameric Streptavidin makes this system useful for the production of multivalent antibody. For the application of this system, we cloned Streptavidin amplified from Streptomyces avidinii chromosome by PCR and fused to gene of hAY4 single-chain Fv antibody specific to death receptor 4 (DR4) which is a receptor for tumor necrosis factor ${\alpha}$ related apoptosis induced ligand. The hAY4 single-chain Fv antibody fused to Streptavidin expressed in Escherichia coli showed 43 kDa monomer in heated SDS-PAGE. However, this fusion protein shown in both non-heated SDS-PAGE and Size-exclusion chromatography exhibited 172 kDa as a tetramer suggesting that natural tetramerization of Streptavidin by non-covalent association induced hAY4 single-chain Fv tetramerization. This fusion protein retained a Biotin binding activity similar to natural Streptavidin as shown in Ouchterlony assay and ELISA. Death receptor 4 antigen binding activity of purified hAY4 single-chain Fv fused to Streptavidin was also confirmed by ELISA and Westernblot. In addition, surface plasmon resonance analysis showed 60-fold higher antigen binding affinity of the hAY4-STR than monomeric hAY4 ScFv due to tetramerization. In summary, hAY4 single-chain Fv fused to Streptavidin fusion protein was successfully expressed and purified as a soluble tetramer in E. coli and showed both Biotin and DR4 antigen binding activity suggesting possible production of bifunctional and tetrameric ScFv antibody.

• The Korean Society of Law and Medicine
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• v.24 no.3
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• pp.155-206
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• 2023

When a person with diminished mental capacity refuses necessary medical care, normative judgments about when paternalistic intervention can be justified come into question. A typical example is involuntary hospitalization for people with mental disabilities, traditionally governed by mental health law. However, Korean civil law reform in 2011 introduced a new form of involuntary hospitalization through guardianship legislation, leading to a dualized system to involuntary hospitalization. Consequently, a conflict has arisen between the 'best interest and surrogate decision-making' paradigm of civil law and the 'social defense and preventive detention' paradigm of mental health law. Many countries have criticized this dualized system as not only inefficient but also unfair. Moreover, the requirement for the presence of 'mental illness' for involuntary hospitalization under mental health law has faced criticism for unfairly discriminating against people with mental disabilities. In response, attempts have been made to integrate guardianship legislation and mental health law based on mental capacity. This study examines the legislative process and framework of the Mental Capacity Act (Northern Ireland) 2016, which reorganized the mental health care system by fusing guardianship legislation with mental health law based on mental capacity. By analyzing the case of Northern Ireland, which has grappled with conflicts between guardianship legislation and mental health law since the 1990s and recently proposed mental capacity as a single, non-discriminatory standard, we aimed to offer insights for the Korean guardianship and mental health systems.

• Journal of the Korean Society of Clothing and Textiles
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• v.32 no.4
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• pp.659-668
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• 2008

Today, Fashion illustration has been diversified in its usage and respotlighted in the significance of its artistry by artists' interpretation and subjective perspectives. The purpose of this study is to find out theoretical reestablishment of this extended expression sphere and possible expression coverage of Fashion illustration. First, based on the Fashion illustration works revealing expressive features of Pop Art, this study reviews major considerations of Fashion illustration, i.e. assemblage, silk screen and new possible perspectives respectively. Therefore, based on the reviews, this study seeks to deduce pop art characteristics of expression technique found in Fashion illustration. Expression modes of Pop Art are represented broadly by assemblage, silk screen and new perspectives. Based on corresponding case analysis, this study could come to find out the following expressive features of pop art revealed in Fashion illustration: First, it is found that contemporary Fashion illustration pursues unbounded expressions and unprecedented styles owing to material variety. Second, it is found that contemporary Fashion illustration tries to adopt new and experimental techniques including computer program. Third, it is found that Fashion illustration characterized mainly by expressive features of Pop Art shows and pioneer a wide variety of application spheres including commercials(ads), newspaper or magazine illustration and cartoon ads simply beyond designer's creative drawing. Furthermore, it is expected that Pop Art's expressive features shown in Fashion illustration will evolve through a fusion with various experimental techniques, and keep having cultural and artistic influence in the future as well.

• Journal of the Korean Ceramic Society
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• v.51 no.5
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• pp.435-441
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• 2014

Silicon carbide-based ceramics and their composites have been studied for application to fusion and advanced fission energy systems. For fission reactors, $SiC_f$/SiC composites can be applied to core structural materials. Multilayered SiC composite fuel cladding, owing to its superior high temperature strength and low hydrogen generation under severe accident conditions, is a candidate for the replacement of zirconium alloy cladding. The SiC composite cladding has to retain its mechanical properties and original structure under the inner pressure caused by fission products; as such it can be applied as a cladding in fission reactor. A hoop strength test using an expandable polyurethane plug was designed in order to evaluate the mechanical properties of the fuel cladding. In this paper, a hoop strength test of the multilayered SiC composite tube for nuclear fuel cladding was simulated using FEA. The stress caused by the plug was distributed nonuniformly because of the friction coefficient difference between the inner surface of the tube and the plug. Hoop stress and shear stress at the tube was evaluated and the relationship between the concentrated stress at the inner layer of the tube and the fracture behavior of the tube was investigated.

• Journal of rehabilitation welfare engineering & assistive technology
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• v.6 no.2
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• pp.31-41
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• 2012

The combination of developed medical devices and the convergence of IT fusion technologies, health variables became to can be measured without discomfort in everyday life regardless of wherever and whenever. because various types of u-Health medical devices have been developed. Also, by considering the users, biological signals can be measured without difference with wearing general clothing, that conductive fabric is being used as smart clothing. However, considering that there is a growing prevalence of the devices and a great interest in the development of u-Health devices, it is urgent to establish performance evaluation. Accordingly, writing guidelines by force to raise checking before marketed or collecting checks after at the market for standard test methods for evaluating the performance. In this paper, it was studied that the possibility of using conductive fabric as electrodes for Wearable u-Health Devices through the material test of the ffabric.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.7
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• pp.3431-3436
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• 2013

Band-notched ultra-wideband (UWB) antennas using frequency selective surfaces (FSSs) are presented. The proposed antennas utilized the band rejection characteristic of typical FSS unit cells. We loaded the FSS unit cells on the same plane of planar UWB antenna. These antennas are designed to reject the interference from the wireless local area network band, 5.15-5.825 GHz in the UWB band, 3.1-10.6 GHz. The measured peak gains of the proposed antennas are more than 2 dBi at both operation edge and center frequencies, and sufficient to apply for commercial purpose. The antennas are small size and planar shape for the purpose of the small mobile application, and enhanced design freedom by using various existing FSS unit cells.

• Journal of the Ergonomics Society of Korea
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• v.31 no.2
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• pp.397-406
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• 2012

Objective: The aim of this study is to determine legible Korean font sizes within in-vehicle information systems(IVISs) in diving conditions. Background: Font legibility within IVISs is one of important causes on its' safe operations during driving. Several researches proposed some guidelines on the legible English font sizes within IVISs. On the contrary, appropriate Korean font sizes have been hardly known in spite of the typological differences between English and Korean. Therefore, more systematic researches for improving the legibility on Korean font size within IVISs have been required. Method: In this study, an experiment was performed with the following experimental factors: the existence of vibration, the color contrasts(white on black, black on white), the font types(HDR, CubeR, Gothic), and the font sizes(6, 8, 10, 12, 14, 16, 18, 20, 22, 24pt). To fit the experimental conditions into real driving environments, the illuminance was controlled to 15lx by using LED lamp and the distance between IVIS and participants was kept to 70cm. Moreover, all participants took the shutter glasses for employing well-known occlusion techniques. Results: The experimental results showed that 'HDR' and 'Non-vibration + Black on white' group took the shortest response time, and decreasing slopes of the response time with increasing font sizes were slowing down at 14pt then flattened out at 22pt regardless of the existence of vibration and color contrasts. Conclusion: The minimum size for legible Korean font would be about 14pt(5.47mm) and the optimum size would be about 22pt(8.59mm). Application: The guideline on the Korean font sizes from this study will be applied to design an IVIS in the future.

• Journal of Digital Convergence
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• v.18 no.6
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• pp.425-433
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• 2020

Digilog book using augmented reality is a form that augmented reality is implemented by illuminating the camera embedded in the mobile image on the page registered as an image marker after downloading the application, which shows a fragmentary limitation in the content implementation method. Therefore, in this study, we proposed a pop-up multi-tracking method that enables two-way interaction in a digit log book using augmented reality technology. Through this, we commissioned an authorized agency to test the technical differentiation of augmented reality content for two prototypes of existing book-type Digilog Book and Pop-up-type Digilog Book. A test report was issued. The pop-up type digit log book suggested in this study enables the user to implement the interactive contents according to the user's action (movement). This can induce the interaction between the virtual image and the printed picture book and give the learner an interest and immersion, so that it is possible to express the interaction of the digital log book.

• Journal of Cadastre & Land InformatiX
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• v.46 no.1
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• pp.3-21
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• 2016

This study analyzes the key factors of 3D spatial information in accordance with the establishment of aerial and ground equipment fusion, and the quality improvement solutions are delivered from the preference survey. Furthermore, it investigates the factors affecting the quality of the individual technical elements through the establishment of three-dimensional spatial information. It is for identifying the priority which needs to be improved, and this data will be used to identify the evaluation for factors, the technology development and its application. For this purpose, the presence or absence of equality is judged by the quantitative techniques through the preference survey of the gap between the experts of spatial information and survey and the general users who have experiences on 3D spatial information.