• Title/Summary/Keyword: Fundamental cause

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A Study on the Fundamental Properties of Concrete Using of the Oyster Shells (굴패각 콘크리트의 기본특성에 관한 연구)

  • Koo, Hae-Shik;Jun, Hak-Su;An, Yong-Deok
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.9 no.3
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    • pp.169-177
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    • 2005
  • This study is to analyze the application of the oyster shells as a substitute fine aggregate of concrete. For this purpose, the fundamental experiments of the composed materials and the variations of the main factors on it were considered and then the variations of workability and strength properties of the specimens with each case were also studied. The experimental results on the properties as construction material showed that the use of oyster shells in concrete would not cause abnormal chemical reactions or lead to the formation of any new objects, the workability and strengths decreased with increase in proportion of oyster shells. The compressive strength of concrete with oyster shells is developed as much as that of normal concrete and the grain size of oyster shells is superior on 3.0~5.0mm and the percentage of substitution of them to fine aggregate about 30% from the properties of concrete with them. The relationship equation between compressive strength and tensile strength is ( ).

Protective effect of dietary oils containing omega-3 fatty acids against glucocorticoid-induced osteoporosis

  • Elbahnasawy, Amr Samir;Valeeva, Emiliya Ramzievna;El-Sayed, Eman Mustafa;Stepanova, Natalya Vladimirovna
    • Journal of Nutrition and Health
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    • v.52 no.4
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    • pp.323-331
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    • 2019
  • Purpose: Glucocorticoids (GCs) are implicated in secondary osteoporosis, and the resulting fractures cause significant morbidity. Polyunsaturated fatty acids (PUFAs) play a vital role in bone metabolism. However, few trials have studied the impact of omega-3 PUFA-containing oils against GC-induced osteoporosis. Therefore, the present study was undertaken to determine whether supplementation with omega-3 PUFA-containing dietary oils such as fish oil, flaxseed oil or soybean oil can impede the development of GC-induced osteoporosis. Methods: The fatty acids (FAs) content of oils was determined using gas chromatography. Male rats were subdivided into 5 groups (8 rats each): normal control (balanced diet), prednisolone control (10 mg/kg prednisolone daily), soybean oil (prednisolone 10 mg/kg + soybean oil 7% w/w), flaxseed oil (prednisolone 10 mg/kg + flaxseed oil 7% w/w), and fish oil (from cod liver; prednisolone 10 mg/kg + fish oil 7% w/w). Results: The study data exhibited a significant depletion in bone mineral density (BMD) and femur mass in the prednisolone control compared to the normal control, accompanied with a marked decrease in the levels of plasma calcium and 1,25-$(OH)_2$-vitamin $D_3$, and elevated levels of C-terminal telopeptide (CTX), tumor necrosis factor-alpha (TNF-${\alpha}$) and malondialdehyde (MDA). Supplementation with fish oil, soybean oil or flaxseed oil helped to improve plasma calcium levels, and suppress oxidative stress and inflammatory markers. Additionally, bone resorption was suppressed as reflected by the decreased CTX levels. However, fish oil was more effective than the other two oils with a significant improvement in BMD and normal histological results compared to the normal control. Conclusion: This study demonstrated that supplementation with dietary oils containing omega-3 PUFAs such as fish oil, soybean oil or flaxseed oil can play a role in the prevention of bone loss and in the regulation of bone metabolism, especially fish oil which demonstrated a greater level of protection against GC-induced osteoporosis.

Study of Legal Issues on Complex Regional Pain Syndrome (CRPS) - Focusing on issues in damage compensation lawsuit - (복합부위통증증후군(CRPS)에 관한 법적 문제 고찰 - 손해배상소송의 쟁점을 중심으로 -)

  • Bae, Hyun-Mo
    • The Korean Society of Law and Medicine
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    • v.11 no.1
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    • pp.91-116
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    • 2010
  • As Complex Regional Pain Syndrome (CRPS) is a new and rare illness, medical cause for it has not yet been clearly found out. Nevertheless, the patients continue to file lawsuits for damage compensation against wrongdoers or their insurers, claiming that the cause of the illness is certain actions of the wrongdoers. Moreover, the claim amount reaches to hundreds of millions of won through billions of won unlike other illnesses. Therefore, CRPS has become an important legal issue in the damage compensation lawsuit. Even though the wound is slight, the development and result may be serious in the case of CRPS. As a result, a sharp conflict arises even regarding medical diagnosis of CRPS in the lawsuit. And, even if the medical diagnosis of CRPS is admitted, severe debates occurs with regard to many issues, which include the causation between accident and CRPS in connection with establishment of damage compensation liability and scope of liability like anamnesis, determination standard of aftereffect disability, and scope of admitted aftereffect medical expense in connection with scope of damage compensation. In this study, I will review fundamental medical research on CRPS up to now and discuss principal legal issues in the damage compensation lawsuit focusing on lower court rulings.

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A Study on the Effects of Nuclear Power Plant Workers and Organizational Characteristics on Accidents (원전 종사자 및 조직 특성이 사고에 미치는 영향)

  • Kim, Byung-Suk;Jo, Hyun-Woong;Oh, Youngmin
    • Korean System Dynamics Review
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    • v.15 no.2
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    • pp.5-25
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    • 2014
  • The purpose of this study is to analyze the effects of nuclear power plant workers and organizational characteristics on accidents, and seek the combination of policies for reducing accidents. For this purpose, it grasped, by using System Dynamics and Causal Loop Diagram, how various factors that cause accidents in nuclear plants are interrelated, and performed simulations after building simulation models. As a result of the analysis, first, the fundamental cause of safety accidents in nuclear power plants turned out to be the time constraint on the workload. Second, it turned out that as the workload of workers increases, physical and mental stresses increase, thereby increasing accidents due to errors and violations. Third, it turned out that as the levels of educational training and compliance with regulations and procedures are enhanced, accidents are reduced. Lastly, it turned out that as the combination of policies (reliance level + working environment + educational training + compliance with regulations and procedures) is increased, accidents are reduced. Especially, it turned out that if the combination of policies is increased by 30%, more than 10 cases of accidents are reduced.

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Association Analysis of Reactive Oxygen Species-Hypertension Genes Discovered by Literature Mining

  • Lim, Ji Eun;Hong, Kyung-Won;Jin, Hyun-Seok;Oh, Bermseok
    • Genomics & Informatics
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    • v.10 no.4
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    • pp.244-248
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    • 2012
  • Oxidative stress, which results in an excessive product of reactive oxygen species (ROS), is one of the fundamental mechanisms of the development of hypertension. In the vascular system, ROS have physical and pathophysiological roles in vascular remodeling and endothelial dysfunction. In this study, ROS-hypertension-related genes were collected by the biological literature-mining tools, such as SciMiner and gene2pubmed, in order to identify the genes that would cause hypertension through ROS. Further, single nucleotide polymorphisms (SNPs) located within these gene regions were examined statistically for their association with hypertension in 6,419 Korean individuals, and pathway enrichment analysis using the associated genes was performed. The 2,945 SNPs of 237 ROS-hypertension genes were analyzed, and 68 genes were significantly associated with hypertension (p < 0.05). The most significant SNP was rs2889611 within MAPK8 (p = $2.70{\times}10^{-5}$; odds ratio, 0.82; confidence interval, 0.75 to 0.90). This study demonstrates that a text mining approach combined with association analysis may be useful to identify the candidate genes that cause hypertension through ROS or oxidative stress.

Investigation of the Cause of High Vibration in a Low Pressure Turbine Casing with Manufacturing Defects by Frequency Response Analysis (주파수 응답해석을 통한 제작공차를 가지는 저압터빈 케이싱의 고진동 원인 규명)

  • Youn, Hee-Chul;Woo, Chang-Ki;Hwang, Jai-Kon
    • Journal of the Korean Society of Manufacturing Technology Engineers
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    • v.24 no.4
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    • pp.463-468
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    • 2015
  • High vibration of a low pressure (LP) turbine casing caused safety problems and life at the facility it was housed in. The main focus of this study was the cause of the high vibration in a low pressure turbine casing with manufacturing defects by frequency response analysis, compared with the results of experiments. Therefore, excited accelerations were obtained from the LP casing fundamental, and frequency responses were analyzed. The measurement and the modal analysis showed that the natural frequency of the LP turbine casing was 61.26 Hz and the excited frequency of the turbine rotor was 60.25 Hz. The manufacturing defect caused a decrease in the casing natural frequency and resulted in the high vibration of the casing because it moved close to the resonant frequency.

A Study on Electrochemical Evaluation Method of Toughness Degradation for 12%Cr Steel (II) (12%Cr강 인성열화도의 전기화학적 평가법에 대한 연구(II))

  • Kim, Chang-Hui;Seo, Hyun-Uk;Yoon, Kee-Bong;Park, Ki-Sung;Kim, Seoung-Tae
    • Proceedings of the KSME Conference
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    • 2001.06a
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    • pp.268-273
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    • 2001
  • Fossil power plants operated in high temperature condition are composed of components such as turbine, boiler, and piping system. Among these components, turbine blades made with 12%Cr steel operate at a temperature above $500^{\circ}C$. Due to the long term service, turbine blades experience material degradation manifested by change in mechanical and microstructural properties. The need to make life assessment and to evaluate material degradation of turbine blade is strongly required but in reality, there is a lack of knowledge in defining failure mechanism and fundamental data for this component. Therefore, in making life assessment of turbine blade, evaluation of material degradation must be a priority. For this purpose, evaluation of toughness degradation is very important. The major cause of toughness degradation in 12Cr turbine blade is reported to be critical corrosion pitting induced by segregation of impurity elements(P etc.), coarsening of carbide, and corrosion, but the of materials for in-service application. In this study, the purpose of research is focused on evaluating toughness degradation with respect to operation time for 12%Cr steel turbine blade under high temperature steam environment and quantitatively detecting the degradation properties which is the cause of toughness degradation by means of non-destructive method, electrochemical polarization.

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Real-time seismic structural response prediction system based on support vector machine

  • Lin, Kuang Yi;Lin, Tzu Kang;Lin, Yo
    • Earthquakes and Structures
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    • v.18 no.2
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    • pp.163-170
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    • 2020
  • Floor acceleration plays a major role in the seismic design of nonstructural components and equipment supported by structures. Large floor acceleration may cause structural damage to or even collapse of buildings. For precision instruments in high-tech factories, even small floor accelerations can cause considerable damage in this study. Six P-wave parameters, namely the peak measurement of acceleration, peak measurement of velocity, peak measurement of displacement, effective predominant period, integral of squared velocity, and cumulative absolute velocity, were estimated from the first 3 s of a vertical ground acceleration time history. Subsequently, a new predictive algorithm was developed, which utilizes the aforementioned parameters with the floor height and fundamental period of the structure as the new inputs of a support vector regression model. Representative earthquakes, which were recorded by the Structure Strong Earthquake Monitoring System of the Central Weather Bureau in Taiwan from 1992 to 2016, were used to construct the support vector regression model for predicting the peak floor acceleration (PFA) of each floor. The results indicated that the accuracy of the predicted PFA, which was defined as a PFA within a one-level difference from the measured PFA on Taiwan's seismic intensity scale, was 96.96%. The proposed system can be integrated into the existing earthquake early warning system to provide complete protection to life and the economy.

Safety Culture, A New Challenge to Human Factors Engineering for 21st Century

  • Lee, Yong-Hee
    • Journal of the Ergonomics Society of Korea
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    • v.35 no.6
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    • pp.473-492
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    • 2016
  • Objective: This paper discusses the recent challenges to human factors engineering due to the safety culture. Background: As incidents occurring in specific fields such as logistics, plant, energy and medical sectors in Korea, as well as in the public sectors including railway, road, aviation and shipping, are recently raised as social issues from the disaster dimension, those incidents are dealt with as man-made disasters in many cases. The trend regarding all accidents as man-made disasters has been expanded in the active perspective that the controllability of all incidents should be ensured in technology development, due to change from a fatal point of view regarding disasters as random occurrence of uncertainties in the past. Method: Man-made disasters are concluded as human errors, and safety culture stands out as a cause of human errors or a new cause item recently. Because safety culture, however, is a very comprehensive term, of which true nature is obscure, although many definitions of safety culture have been presented, the safety culture may make avoid the true nature and responsibility of an incident, or make the main player and subject obscure. Raising safety culture as a cause without presenting a specific countermeasure will be just a wisdom of hindsight. Results and Conclusion: This study reviews the fundamental discussions on "Is safety culture a task of human factors engineering?" and the existing approach carried out from various perspectives in order to seek an effective approach on the new task of safety culture in the human factors engineering field. This study discusses an engineering approach to meet a precondition that safety culture is not just an added factor through a review of the approaches in the proactive fields such as nuclear power and aviation, and the traditional approaches of human factors engineering. Application: This study especially defines the perspective of socio-technological system that has expanded the existing man-machine system, and discusses a systemic approach embracing various interactions, and several overriding tasks.

Assessment of Priority Order Using the Chemical to Cause to Generate Occupational Diseases and Classification by GHS (직업병발생 물질과 GHS분류 자료를 이용한 화학물질 우선순위 평가)

  • Baik, Nam-Sik;Chung, Jin-Do;Park, Chan-Hee
    • Journal of Environmental Science International
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    • v.19 no.6
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    • pp.715-735
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    • 2010
  • This study is designed to assess the priority order of the chemicals to cause to generate occupational diseases in order to understand the fundamental data required for the preparation of health protective measure for the workers dealing with chemicals. The 41 types of 51 ones of chemicals to cause to generate the national occupational diseases were selected as the study objects by understanding their domestic use or not, and their occupational diseases' occurrence or not among 110,608 types of domestic and overseas chemicals. To assess their priority order the sum of scores was acquired by understanding the actually classified condition based on a perfect score of physical riskiness(90points) and health toxicity(92points) as a classification standard by GHS, the priority order on GHS riskiness assessment, GHS toxicity assessment, GHS toxic xriskiness assessment(sum of riskiness plus toxicity) was assessed by multiplying each result by each weight of occupational disease's occurrence. The high ranking 5 items of chemicals for GHS riskiness assessment were turned out to be urethane, copper, chlorine, manganese, and thiomersal by order. Besides as a result of GHS toxicity assessment the top fives were assessed to be aluminum, iron oxide, manganese, copper, and cadium(Metal) by order. On the other hand, GHS toxicity riskiness assessment showed that the top fives were assessed to be copper, urethane, iron oxide, chlorine and phenanthrene by order. As there is no material or many uncertain details for physical riskiness or health toxicity by GHS classification though such materials caused to generate the national occupational diseases, it is very urgent to prepare its countermeasure based on the forementioned in order to protect the workers handling or being exposed to chemicals from health.