• Title/Summary/Keyword: Functional Imaging

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INDUSTRIAL MATHEMATICS IN ULTRASOUND IMAGING

  • JANG, JAESEONG;AHN, CHI YOUNG
    • Journal of the Korean Society for Industrial and Applied Mathematics
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    • v.20 no.3
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    • pp.175-202
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    • 2016
  • Ultrasound imaging is a widely used tool for visualizing human body's internal organs and quantifying clinical parameters. Due to its advantages such as safety, non-invasiveness, portability, low cost and real-time 2D/3D imaging, diagnostic ultrasound industry has steadily grown. Since the technology advancements such as digital beam-forming, Doppler ultrasound, real-time 3D imaging and automated diagnosis techniques, there are still a lot of demands for image quality improvement, faster and accurate imaging, 3D color Doppler imaging and advanced functional imaging modes. In order to satisfy those demands, mathematics should be used properly and effectively in ultrasound imaging. Mathematics has been used commonly as mathematical modelling, numerical solutions and visualization, combined with science and engineering. In this article, we describe a brief history of ultrasound imaging, its basic principle, its applications in obstetrics/gynecology, cardiology and radiology, domestic-industrial products, contributions of mathematics and challenging issues in ultrasound imaging.

Neuropsychiatric Evaluation of Head-Injured Patients(II) : A Comparative Study of Brain-injured Patients with and without Abnormal Findings in the Structural Brain Imaging - Mainly in Relation to Functional Brain Studies and Psychological Evaluation (두부외상 환자의 신경정신의학적 평가(II) : 뇌의 구조적 영상검사상의 병변 유무에 따른 두부외상 환자군의 비교 - 기능적 및 심리적 검사소견과의 연관성을 중심으로)

  • Cho, Seoung Wook;Chang, Hwan-Il
    • Korean Journal of Biological Psychiatry
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    • v.3 no.1
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    • pp.66-74
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    • 1996
  • There has been an increase in head trauma due to rapid industralization and improvement in transportation. This poses difficulties in differentiating between neuropsychiatric disabilities resulting from real organic changes and those arising from compensation issues. It is the purpose of this study to seek out the differences between normal and abnormal finding group in the structural brain imaging studies via the results of the functional brain imaging studies and psychological tests. Out of 132 subjects, 62 comprised normal and 70 the abnormal finding group. EEG and SPECT were chosen for inspection of functional brain imaging. MMPI and K-WAIS were chosen for psychological test. The subjects were further divided into right hemispheric damage, left hemispheric damage, both hemispheric damage, diffuse damage group and negative group in order to find out whether any differences in the psychological lest results could be localized. The results are as follows : 1) The abnormal finding group, the EEG and SPECT were proven to be a good predictor of brain lesion. This implies that even in the functional brain studies, abnormalities are more easily detected if there are visible brain lesions. 2) The FSIQ of the abnormal finding group is lower than that of normal finding group. this difference is mainly due to low V1Q. The left hemispheric damage group lend to shaw low V1Q. This lowered in was the difference between left hemispheric damage group and negative group. Furthermore, there were no group differences in the PIQ. It is concluded that K-WAIS is effective as evaluator of VIQ mainly of those patients with left hemispheric damage and it is ineffective as a evaluator of PIQ. 3) In the MMPI profile, the both groups displayed high neurotic profiles. There was no difference in the psychotic profiles. The scores of the Depression and Hystery were high in abnormal finding group. This can be seen as one of the lypical findings of chronic head trauma patients. 4) The abnormal finding group tend to be diagnosed as organic mental disorder in the psychological tests more frequently.

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Functional beamforming for high-resolution ultrasound imaging in the air with random sparse array transducer (고해상도 공기중 초음파 영상을 위한 기능성 빔형성법 적용)

  • Choon-Su Park
    • The Journal of the Acoustical Society of Korea
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    • v.43 no.3
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    • pp.361-367
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    • 2024
  • Ultrasound in the air is widely used in industry as a measurement technique to prevent abnormalities in the machinery. Recently, the use of airborne ultrasound imaging techniques, which can find the location of abnormalities using an array transducers, is increasing. A beamforming method that uses the phase difference for each sensor is used to visualize the location of the ultrasonic sound source. We exploit a random sparse ultrasonic array and obtain beamforming power distribution on the source in a certain distance away from the array. Conventional beamforming methods inevitably have limited spatial resolution depending on the number of sensors used and the aperture size. A high-resolution ultrasound imaging technique was implemented by applying functional beamforming as a method to overcome the geometric constraints of the array. The functional beamforming method can be expressed as a generalized beam forming method mathematically, and has the advantage of being able to obtain high-resolution imaging by reducing main-lobe width and side lobes. As a result of observation through computer simulation, it was verified that the resolution of the ultrasonic source in the air was successfully increased by functional beamforming using the ultrasonic sparse array.

Late reconstruction of extensive orbital floor fracture with a patient-specific implant in a bombing victim

  • Smeets, Maximiliaan;Snel, Robin;Sun, Yi;Dormaar, Titiaan;Politis, Constantinus
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.46 no.5
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    • pp.353-357
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    • 2020
  • Fractures of the orbital floor and walls are among the most frequent maxillofacial fractures. Virtual three-dimensional (3D) planning and use of patient-specific implants (PSIs) could improve anatomic and functional outcomes in orbital reconstruction surgery. The presented case was a victim of a terrorist attack involving improvised explosive devices. This 58-year-old female suffered severe wounds caused by a single piece of metal from a bomb, shattering the left orbital floor and lateral orbital wall. Due to remaining hypotropia of the left eye compared to the right eye, late orbital floor reconstruction was carried out with a personalised 3D printed titanium implant. We concluded that this technique with PSI appears to be a viable method to correct complex orbital floor defects. Our research group noted good aesthetic and functional results one year after surgery. Due to the complexity of the surgery for a major bony defect of the orbital floor, it is important that the surgery be executed by experienced surgeons in the field of maxillofacial traumatology.

Nuclear Medicine Imaging Diagnosis in Infectious Bone Diseases (감염성 골질환의 핵의학 영상진단)

  • Choi, Yun-Young
    • Nuclear Medicine and Molecular Imaging
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    • v.40 no.4
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    • pp.193-199
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    • 2006
  • Infectious and inflammatory bone diseases include a wide range of disease process, depending on the patient's age, location of infection, various causative organisms, duration from symtom onset, accompanied fracture or prior surgery, prosthesis insertion, and underlying systemic disease such as diabetes, etc. Bone infection may induce massive destruction of bones and joints, results in functional reduction and disability. The key to successful management is early diagnosis and proper treatment. Various radionuclide imaging methods including three phase bone scan, Ga-67 scan, WBC scan, and combined imaging techniques such as bone/Ga-67 scan, WBC/bone marrow scan add complementary role to the radiologic imaging modalities including plain radiography, CT and MRI. F-18 FDG PET imaging also has recently been introduced in diagnosis of infected prosthesis and chronic active osteomyelitis. Selection of proper nuclear medicine imaging method will improve the diagnostic accuracy of infections and inflammatory bone diseases, based on understading of pathogenesis and radiologic imaging findings.

Numerical Evaluations of the Effect of Feature Maps on Content-Adaptive Finite Element Mesh Generation

  • Lee, W.H.;Kim, T.S.;Cho, M.H.;Lee, S.Y.
    • Journal of Biomedical Engineering Research
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    • v.28 no.1
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    • pp.8-16
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    • 2007
  • Finite element analysis (FEA) is an effective means for the analysis of bioelectromagnetism. It has been successfully applied to various problems over conventional methods such as boundary element analysis and finite difference analysis. However, its utilization has been limited due to the overwhelming computational load despite of its analytical power. We have previously developed a novel mesh generation scheme that produces FE meshes that are content-adaptive to given MR images. MRI content-adaptive FE meshes (cMeshes) represent the electrically conducting domain more effectively with far less number of nodes and elements, thus lessen the computational load. In general, the cMesh generation is affected by the quality of feature maps derived from MRI. In this study, we have tested various feature maps created based on the improved differential geometry measures for more effective cMesh head models. As performance indices, correlation coefficient (CC), root mean squared error (RMSE), relative error (RE), and the quality of cMesh triangle elements are used. The results show that there is a significant variation according to the characteristics of specific feature maps on cMesh generation, and offer additional choices of feature maps to yield more effective and efficient generation of cMeshes. We believe that cMeshes with specific and improved feature map generation schemes should be useful in the FEA of bioelectromagnetic problems.

Advances in Functional Connectomics in Neuroscience : A Focus on Post-Traumatic Stress Disorder (뇌과학 분야 기능적 연결체학의 발전 : 외상후스트레스장애를 중심으로)

  • Park, Shinwon;Jeong, Hyeonseok S.;Lyoo, In Kyoon
    • Korean Journal of Biological Psychiatry
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    • v.22 no.3
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    • pp.101-108
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    • 2015
  • Recent breakthroughs in functional neuroimaging techniques have launched the quest of mapping the connections of the human brain, otherwise known as the human connectome. Imaging connectomics is an umbrella term that refers to the neuroimaging techniques used to generate these maps, which recently has enabled comprehensive brain mapping of network connectivity combined with graph theoretic methods. In this review, we present an overview of the key concepts in functional connectomics. Furthermore, we discuss articles that applied task-based and/or resting-state functional magnetic resonance imaging to examine network deficits in post-traumatic stress disorder (PTSD). These studies have provided important insights regarding the etiology of PTSD, as well as the overall organization of the brain network. Advances in functional connectomics are expected to provide insight into the pathophysiology and the development of biomarkers for diagnosis and treatment of PTSD.