• Molecules and Cells
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• 제27권6호
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• pp.629-634
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• 2009

G protein-coupled receptors (GPCRs) are part of multi-protein networks called 'receptosomes'. These GPCR interacting proteins (GIPs) in the receptosomes control the targeting, trafficking and signaling of GPCRs. PDZ domain proteins constitute the largest protein family among the GIPs, and the predominant function of the PDZ domain proteins is to assemble signaling pathway components into close proximity by recognition of the last four C-terminal amino acids of GPCRs. We present here a machine learning based approach for the identification of GPCR-binding PDZ domain proteins. In order to characterize the network of interactions between amino acid residues that contribute to the stability of the PDZ domain-ligand complex and to encode the complex into a feature vector, amino acid contact matrices and physicochemical distance matrix were constructed and adopted. This novel machine learning based method displayed high performance for the identification of PDZ domain-ligand interactions and allowed the identification of novel GPCR-PDZ domain protein interactions.

• 전기학회논문지
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• 제66권9호
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• pp.1364-1372
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• 2017

In this paper, a problem of event-triggered model predictive control is investigated for continuous-time Takagi-Sugeno (T-S) fuzzy systems with input quantization. To efficiently utilize network resources, event-trigger is employed, which transmits limited signals satisfying the condition that the measurement of errors is over the ratio of a certain level. Considering sampling and quantization, continuous Takagi-Sugeno (T-S) fuzzy systems are regarded as a sector bounded continuous-time T-S fuzzy systems with input delay. Then, a model predictive controller (MPC) based on parallel distributed compensation (PDC) is designed to optimally stabilize the closed loop systems. The proposed MPC optimize the objective function over infinite horizon, which can be easily calculated and implemented solving linear matrix inequalities (LMIs) for every event-triggered time. The validity and effectiveness are shown that the event triggered MPC can stabilize well the systems with even smaller average sampling rate and limited actuator signal guaranteeing optimal performances through the numerical example.

• Structural Engineering and Mechanics
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• 제68권4호
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• pp.399-408
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• 2018

Cable supported structures have been widely used in civil engineering. Cable tension estimation has great importance in cable supported structures' analysis, ranging from design to construction and from inspection to maintenance. Even though the Bernoulli-Euler beam element is commonly used in the traditional finite element method for calculation of frequency and cable tension estimation, many elements must be meshed to achieve accurate results, leading to expensive computation. To improve the accuracy and efficiency, a dynamic finite element method for estimation of cable tension is proposed. In this method, following the dynamic stiffness matrix method, frequency-dependent shape functions are adopted to derive the stiffness and mass matrices of an exact beam element that can be used for natural frequency calculation and cable tension estimation. An iterative algorithm is used for the exact beam element to determine both the exact natural frequencies and the cable tension. Illustrative examples show that, compared with the cable tension estimation method using the conventional beam element, the proposed method has a distinct advantage regarding the accuracy and the computational time.

• 한국생물정보학회:학술대회논문집
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• 한국생물정보시스템생물학회 2004년도 The 3rd Annual Conference for The Korean Society for Bioinformatics Association of Asian Societies for Bioinformatics 2004 Symposium
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• pp.244-249
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• 2004

There have been many attempts to predict the secondary structure content of a protein from its primary sequence, which serves as the first step in a series of bioinformatics processes to gain knowledge of the structure and function of a protein. Most of them assumed that prediction relying on the information of the amino acid composition of a protein can be successful. Several approaches expanded the amount of information by including the pair amino acid composition of two adjacent residues. Recent methods achieved a remarkable improvement in prediction accuracy by using this expanded composition information. The overall average errors of two successful methods were 6.1% and 3.4%. This work was motivated by the observation that evolutionarily related proteins share the similar structure. After manipulating the values of the frequency matrix obtained by running PSI-BLAST, inputs of an artificial neural network were constructed by taking the ratio of the amino acid composition of the evolutionarily related proteins with a query protein to the background probability. Although we did not utilize the expanded composition information of amino acid pairs, we obtained the comparable accuracy, with the overall average error being 3.6%.

• 정보처리학회논문지C
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• 제9C권4호
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• pp.445-452
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• 2002

본 논문에서는 수학적인 이론에 기반한 안전성이 증명 가능한 128 비트 블록 암호 알고리즘을 제안한다. 제안된 SPN 구조 암호 알고리즘에 사용된 active S-box가 많은 16$\times$16 선형변환을 찾았고, 안전성에 대한 증명 방법으로 차분 해독(Differential Cryptanalysis)와 선형해독(Linear Cryptanalysis)에 대하여 증명하였다. 또한 DC와 LC에 영향을 주는 128 비트 블록 암호 알고리즘의 라운드 별 active S-box의 최소 개수, 최대 차분 확률과 최대 선형확률을 구하였다.

• ETRI Journal
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• 제27권6호
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• pp.691-696
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• 2005

In asynchronous transfer mode (ATM) networks, fixed length cells of 53 bytes are transmitted. A cell may be discarded during transmission due to buffer overflow or a detection of errors. Cell discarding seriously degrades transmission quality. The quality degradation can be reduced by employing efficient forward error control (FEC) to recover discarded cells. In this paper, we present the design and implementation of decoding equipment for FEC in ATM networks based on a single parity check (SPC) product code using very-large-scale integration (VLSI) technology. FEC allows the destination to reconstruct missing data cells by using redundant parity cells that the source adds to each block of data cells. The functionality of the design has been tested using the Model Sim 5.7cXE Simulation Package. The design has been implemented for a $5{\times}5$ matrix of data cells in a Virtex-E XCV 3200E FG1156 device. The simulation and synthesis results show that the decoding function can be completed in 81 clock cycles with an optimum clock of 56.8 MHz. A test bench was written to study the performance of the decoder, and the results are presented.

• KIEE International Transactions on Electrophysics and Applications
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• 제5C권4호
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• pp.165-170
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• 2005

A series of inorganic-organic hybrid membranes were prepared with a systematic variation of titanium dioxide nanoparticle content. Their water uptake, methanol permeability and proton conductivity as a function of temperature were investigated. The results obtained show that the inorganic oxide network decreases the proton conductivity and water swelling. It is also found that increase in inorganic oxide content leads to decrease of methanol permeability. In terms of the morphology, membranes are homogeneous and exhibit good adhesion between inorganic domains and the polymer matrix. The properties of the composite membranes are compared with the standard nafion membrane.

• International journal of advanced smart convergence
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• 제11권2호
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• pp.108-117
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• 2022

The recent development of information and communication technology has a great impact on the audio/video industry. In particular, IP-based AoIP transmission technology and AVB technology are making changes in the audio/video market. Video signal transmission technology has been introduced to the market through a network, but it has not replaced the video switcher function. Video signals in the conference room or classroom are still controlled by the switching device. In order to switch input/output video devices, a cable that is not limited by distance must be connected to the switcher. In addition, the control of the switching device must be performed by a person who has received professional training. In this paper, it is a technology that can be operated even by non-experts by replacing complex video cables (RGB, DVI, HDMI, DP) with LAN cables and enabling IP-based video switching and transmission (Video Mirroring over IP: VMoIP) to replace video switcher equipment. We are going to do this study, I/O videos were controlled in the form of matrix and high-definition videos were transmitted without distortion, and VMoIP is expected to become the standard for video switching systems in the future.

• 한국환경복원기술학회지
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• 제11권6호
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• pp.11-25
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• 2008

In broad agreement on the need for forests in the city, researches on the urban forest are being actively carried out. Nonetheless, since these researches focus on functional usage within living spaces, finding methods for creation of urban forests and technical solutions have remained chief issues as a consequence. This paper, which attempts to historically examine the properties of the urban forest within living space, has the characteristics of researching basic angles for approaching the creation of contemporary urban forests. For this purpose Joseon Dynasty genre paintings, which represent living conditions of Joseon era, have been decided as theme of the paper. Particularly the focus was limited to genre paintings depicting trees, giving phenomenal observations. As a result, some remarkable characteristics emerged as functional urban forest, symbolic urban forest, topological urban forest, and appreciative urban forest. Urban forest within living space mainly appear as functional, showing an even distribution in small numbers rather than gathering in large groups. The following can be inferred regarding this and related to the setting up of the scope of, and creating of, contemporary urban forest : First, from the viewpoint of urban forest creation there is a need to study more subdivided and refined types of the urban forest and to actually realize these types. Second, from the viewpoint of urban forest usage, one needs to approach existing forests, ranging from small-scale including invididual trees, to mid-, large-, and super scale, as urban forests. In this, a network of major trees, and thereby a matrix of all trees formed by that network, will be formed. Third, from the viewpoint of urban forest improvement, approaches need to be based on planting trees in even distribution across the whole city.

• Molecules and Cells
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• 제40권9호
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• pp.685-695
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• 2017

Obesity and the metabolic disorders that constitute metabolic syndrome are a primary cause of morbidity and mortality in the world. Nonetheless, the changes in the proteins and the underlying molecular pathways involved in the relevant pathogenesis are poorly understood. In this study a proteomic analysis of the visceral adipose tissue isolated from metabolically healthy and unhealthy obese patients was used to identify presence of altered pathway(s) leading to metabolic dysfunction. Samples were obtained from 18 obese patients undergoing bariatric surgery and were subdivided into two groups based on the presence or absence of comorbidities as defined by the International Diabetes Federation. Two dimensional difference in-gel electrophoresis coupled with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry was carried out. A total of 28 proteins were identified with a statistically significant difference in abundance and a 1.5-fold change (ANOVA, $p{\leq}0.05$) between the groups. 11 proteins showed increased abundance while 17 proteins were decreased in the metabolically unhealthy obese compared to the healthy obese. The differentially expressed proteins belonged broadly to three functional categories: (i) protein and lipid metabolism (ii) cytoskeleton and (iii) regulation of other metabolic processes. Network analysis by Ingenuity pathway analysis identified the $NF{\kappa}B$, IRK/MAPK and PKC as the nodes with the highest connections within the connectivity map. The top network pathway identified in our protein data set related to cellular movement, hematological system development and function, and immune cell trafficking. The VAT proteome between the two groups differed substantially between the groups which could potentially be the reason for metabolic dysfunction.