• Title/Summary/Keyword: Function division

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The Fault Tolerant Evaluation Model due to the Periodic Automatic Fault Detection Function of the Safety-critical I&C Systems in the Nuclear Power Plants (원전 안전필수 계측제어시스템의 주기적 자동고장검출기능에 따른 고장허용 평가모델)

  • Hur, Seop;Kim, Dong-Hoon;Choi, Jong-Gyun;Kim, Chang-Hwoi;Lee, Dong-Young
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.62 no.7
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    • pp.994-1002
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    • 2013
  • This study suggests a generalized availability and safety evaluation model to evaluate the influences to the system's fault tolerant capabilities depending on automatic fault detection function such as the automatic periodic testings. The conventional evaluation model of automatic fault detection function deals only with the self diagnostics, and supposes that the fault detection coverage of self diagnostics is always constant. But all of the fault detection methods could be degraded. For example, the periodic surveillance test has the potential human errors or test equipment errors, the self diagnostics has the potential degradation of built-in logics, and the automatic periodic testing has the potential degradation of automatic test facilities. The suggested evaluation models have incorporated the loss or erroneous behaviors of the automatic fault detection methods. The availability and the safety of each module of the safety grade platform have been evaluated as they were applied the automatic periodic test methodology and the fault tolerant evaluation models. The availability and safety of the safety grade platform were improved when applied the automatic periodic testing. Especially the fault tolerant capability of the processor module with a weak self-diagnostics and the process parameter input modules were dramatically improved compared to the conventional cases. In addition, as a result of the safety evaluation of the digital reactor protection system, the system safety of the digital parts was improved about 4 times compared to the conventional cases.

Systemic White Blood Cell Count as a Biomarker Associated with Severity of Chronic Obstructive Lung Disease

  • Koo, Hyeon-Kyoung;Kang, Hyung Koo;Song, Pamela;Park, Hye Kyeong;Lee, Sung-Soon;Jung, Hoon
    • Tuberculosis and Respiratory Diseases
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    • v.80 no.3
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    • pp.304-310
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    • 2017
  • Background: Chronic obstructive pulmonary disease (COPD), is a chronic inflammatory disorder. We evaluated whether white blood cell (WBC) count, is associated with the severity of COPD, independent of other inflammatory conditions, such as metabolic syndrome. Methods: The WBC counts were compared between 1227 COPD patients and 8679 non-COPD adults older than 40. The relationships between the WBC count, lung function, and symptoms score in COPD patients, were determined, using general linear regression analyses. Results: The WBC count was negatively associated with forced vital capacity (FVC, L), FVC (% predicted), forced expiry volume in one second ($FEV_1$, L), and $FEV_1$ (% predicted) in COPD patients. Additionally, the WBC count was independently associated with the quality of life measure, by EQ5D-index score. However, this relationship between WBC count, and disease severity, was not significant in current smokers, because of the confounding effect of smoking, on the WBC count. Conclusion: The WBC count is associated with current smoking status and COPD severity, and a risk factor for poor lung function, and quality of life, especially in non-currently smoking COPD patients. The WBC count can be used, as an easily measurable COPD biomarker.

Taxonomic and Functional Changes of Bacterial Communities in the Rhizosphere of Kimchi Cabbage After Seed Bacterization with Proteus vulgaris JBLS202

  • Bhattacharyya, Dipto;Duta, Swarnalee;Yu, Sang-Mi;Jeong, Sang Chul;Lee, Yong Hoon
    • The Plant Pathology Journal
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    • v.34 no.4
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    • pp.286-296
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    • 2018
  • Maintenance of a beneficial microbial community, especially in the rhizosphere, is indispensable for plant growth and agricultural sustainability. In this sense, plant growth-promoting rhizobacteria (PGPR) have been extensively studied for their role in plant growth promotion and disease resistance. However, the impact of introducing PGPR strains into rhizosphere microbial communities is still underexplored. We previously found that the Proteus vulgaris JBLS202 strain (JBLS202) promoted growth of Kimchi cabbage and altered the relative abundance of total bacteria and Pseudomonas spp. in the treated rhizosphere. To extend these findings, we used pyrosequencing to analyze the changes in bacterial communities in the rhizosphere of Kimchi cabbage after introduction of JBLS202. The alterations were also evaluated by taxon-specific realtime PCR (qPCR). The pyrosequencing data revealed an increase in total bacteria abundance, including specific groups such as Proteobacteria, Acidobacteria, and Actinobacteria, in the treated rhizosphere. Time-course qPCR analysis confirmed the increase in the abundance of Acidobacteria, Actinobacteria, Alphaproteobacteria, and Betaproteobacteria. Furthermore, genes involved in nitrogen cycling were upregulated by JBLS202 treatment indicating changes in ecological function of the rhizosphere soil. Overall, these results indicate that introduction of JBLS202 alters both the composition and function of the rhizosphere bacterial community, which can have direct and indirect effects on plant growth. Therefore, we propose that long-term changes in bacterial composition and community-level function need to be considered for practical use of PGPRs.

Comparisons of Discriminant Analysis Model and Generalized Logit Model in Stroke Patten Identifications Classification (중풍변증분류에 사용되는 판별분석모형과 일반화로짓모형의 비교)

  • Kang, Byoung-Kab;Lee, Ju-Ah;Ko, Mi-Mi;Moon, Tae-Woong;Bang, Ok-Sun
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.25 no.2
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    • pp.318-321
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    • 2011
  • In this study, when a physician make a diagnosis of the Pattern Identifications(PIs) of stroke patients, the development methods of the PIs classification function is considered by diagnostic questionnaire of the PIs for stroke patients. Clinical data collected from 1,502 stroke patients who was identically diagnosed for the PIs subtypes diagnosed by two clinical experts with more than 3 years experiences in 13 oriental medical hospitals. In order to develop the classification function into PIs using the 44 items-Fire&heat(19), Qi-deficiency(11), Yin-deficiency(7), Dampness phlegm(7)- of them was significant statistically by univariate analysis in 61 questionnaires totally, we make some comparisons of the results of discriminant analysis model and generalized logit model. The overall diagnostic accuracy rate of the PIs subtypes for discriminant model(74.37%) was higher than 3% of generalized logit model(70.09%).

Pulmonary Function and Its Influence Factors of Elementary School Children in Gangneung (강릉지역 초등학생들의 폐기능과 영향 요인 분석)

  • Yu, Seung-Do;Yoo, Si-Eun;Lee, Min-Jung;Choi, Wook-Hee;Kim, Dae-Seon;Lee, Chul-Ho;Park, Kyung-Hwa
    • Journal of Environmental Health Sciences
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    • v.34 no.1
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    • pp.20-26
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    • 2008
  • The objective of the study which utilised population based data was to determine the respiratory condition of elementary school children in Gangneung. From October 9th to December 14th, 2006, Pulmonary Function Tests (PFT) including Forced Vital Capacity (FVC) and Forced Expiratoy Volume in I Second $(FEV_1)$ were conducted on the target group of children using a spirometer. The prevalence of asthmatic symptoms was 29.8% among boys and 39.6% among girls. By using logistic regression, we found that family history of allergic rhinitis (OR=3.90, CI=1.05-14.51), experience of allergic conjunctivitis (OR=4.67, CI=1.54-14.16) and atopic dermatitis (OR=2.86, CI=1.17-7.05) significantly increased the asthmatic symptoms. Also, a family history of asthma and food allergy were associated with asthmatic symptoms. In relation to housing and environmental risk factors, residences under the ground (OR=3.59, CI=1.35-9.51) and big-size dolls (OR=2.71, CI=0.86-8.53) significantly increased the prevalence of asthmatic symptoms. For PFT, above four families, exposure of passive smoking and pets significantly reduced FVC in both groups (p<0.05). In girls, a big-size doll was significantly associated with decreased lung function (FVC and $FEV_1$). In boys, using bed significantly reduced $FEV_1$. Also, the risk of asthmatic symptoms was found to increase when the house has been built for 5 years or more, the house is close to a road $({\leq}100m)$, a gas/Kerosene heater or carpet is utilized within the house. However, their differences were not significant. It is concluded that genetic factor such as a family history of respiratory disease, allergic symptoms and housing risk factor are related to asthmatic symptoms. These results were worth noting because the findings will help address risk factors related respiratory symptoms especially in relation to housing and environment.

Clinical effects of AF-365 for maintenance therapy in chronic stages of asthmas (천식 완해기 유지치료로서 AF-365의 임상적 효과)

  • Jeong, Seung-Yeon;Lee, Jae-Sung;Choi, Jun-Yong;Lee, Kun-Young;Jung, Hee-Jae;Rhee, Hyung-Koo;Bae, Hyun-Su;Jung, Sung-Ki
    • The Journal of Internal Korean Medicine
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    • v.26 no.1
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    • pp.1-11
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    • 2005
  • Backgrounds : Gamichungsangboha-tang extract has been known to improve pulmonary functions and quality of life within four weeks of treatment. Cessation of treatment causes recurrence of symptoms and regression of pulmonary function and poorer quality of life. Long-term herbal therapy is difficult to maintain due to economic burden and other reasons. AF-365 is made with reduced dosage of Gamichungsangboha-tang extract. This study was designed to evaluate the effectiveness of AF-365 for maintenance therapy. Materials and Methods : The subjects consisted of 27 patients with asthma who had beed treated with AF-365 for four weeks. First, patients were treated with Gamichungsangboha-tang extract for four weeks. Second patients stopped herbal medicine for four weeks and after that they took AF-365. Pulmonary function test(PFT) was checked before and after four weeks of treatment. Quality of Life Questionnaire for Adult Korean Asthmatics(QLQAKA) was checked every two weeks from the beginning. The effects of AF-365 were analysed throughout the last four weeks. Results : Treatment of AF-365 for four weeks resulted in significant increase in PEFR%, QLQAKA. The QLQAKA of the step3, step4 group classified by Global initiative for asthma(GINA) showed significant improvement, and the QLQAKA of the step2 group showed no significant difference. In step3 group, PEFR% increased significantly. Conclusions : This study supports a role for AF-365 in maintenance of pulmonary function and quality of life, especially in persistent symptomatic asthmatics.

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A Study on a Macroscopic Evaluation Method of Forest Recreation Function (산림 휴양기능의 거시적 평가방법에 관한 연구)

  • Chae, Mie Oak;Lee, Kilyong;Jun, Eunsun;Song, Ha Seung
    • Journal of Korean Society of Forest Science
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    • v.104 no.2
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    • pp.267-276
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    • 2015
  • This study suggests a macroscopic method of evaluating forest recreation function based on physical characteristics of forests. The method was verified by a correlation between forest recreation function in popular top 45 mountains and popularity among them, with using data-mountain area, height, distance between mountain and cities, population around mountain, and size of public service. According to analysis of the forest recreation function, it is shown that top 8 mountains, including Jirisan and Seoraksan, provide over 64% of total recreation function, while they serve the function relatively lower than mountains near mega cities-Bukhansan in Seoul-do, in terms of the function per unit area ($km^2$). It is because, in a case of national and provincial mountains, the size of mountain is likely a critical factor for determining recreation function and the distance influences on it relatively lower. These findings implicate that a large size of forests bring the recreation function to visitors on nationwide level, whileas forests in suburban provide intensively it to near population to near population.