• Archives of Pharmacal Research
• /
• v.19 no.5
• /
• pp.400-405
• /
• 1996

In vitro studies were conducted to dertermine the frequency rate of spontaneous resistance to LB20304 and to dertermine whether cross-resistance to other antimicrobial agents develops. In eight strains of bacteria, the frequency of mutation to LB20304 at the concentrations of four and eight times the minimal inhibitory concentration(MIC) ranaged from less than 4.0 ${\times}$ $10^{-10}$ to 2.2 $\{times}$ $10^{-10}$ . These results were similar to those founf for other new fluoroquinolones. THe development of stepwise resistance was determined by repeated subculture in broth in the presence of increasing concentration of the compounds. Exposure of bacteria to increasing concentrations of LB20304 resulted in the selection of organisms with higher MICs. There were 4- to 128-fold increases in the MIC of LB20304 for bacterial strains of Staphylococcus aureus, Streptococcus pneumoniae, Escherichia coli and Pseudomonas aeruginosa. However, those strains selected after repeated exposure were well within the susceptibility range for LB20304 except for Pseudomonas aeruginosa. The resistant isolates selected with LB20304 showed cross-resistance when tested against ciprofloxacin and vice versa.

• Korean Journal of Applied Biomechanics
• /
• v.18 no.4
• /
• pp.49-57
• /
• 2008

The purpose of this study was to determine the effects of 12-week elastic resistance exercise for the elderly on the magnitude of frequency and variability of ground reaction force signals. To this aim, total 12 elderly women aged in their 70 were participated in this study and asked to do a 12-week elastic resistance exercise program. FFT(fast Fourier Transform) was used to analyze the frequency domain analysis of the ground reaction forces's signals and an accumulative PSD (power spectrum density) normalized by support phase of walking was calculated to reconstruct the certain signals. To estimate the gait stability between the before and after exercise, values of variability were determined in a coefficient of variance. The magnitude of frequency and variability analysis for media-lateral signal revealed significantly less after exercise (p<.05). In contrast, variability of this signal's frequency that have used to evaluate the local stability during walking exhibited significantly greater after exercise(p<.05). In summary, magnitude frequency and variability of media-lateral ground reaction force's signal were significantly changed after a 12-week elastic resistance exercise.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
• /
• v.17 no.2
• /
• pp.171-177
• /
• 2004

Voltage step-down characteristics in Ring/Dot type piezoelectric transformer were examined as a function of the area of input electrode when the area of output electrode is fixed. The effects of driving frequency and load resistance on the voltage step-down characteristics were also examined. Voltage gain was greatly dependent on the driving frequency and load resistance, and showed a maximum gain at resonance frequency of the step-down transformer. The frequency where the maximum cutout voltage appears increased about 0.2％ as the load resistance increased from 10 to 150 Ω. As the area of input electrode increased, the voltage gain and the efficiency of the transformer increased. Frequency dependence of efficiency of the step-down transformer revealed a similar tendency with the voltage gain curves. The maximum efficiency remarked 94% when the input voltage and the load resistance were 20 Vpp and 120 Ω, respectively.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
• /
• 2004.07b
• /
• pp.722-725
• /
• 2004

Voltage step-down characteristics in Ring/Dot type piezoelectric transformer were examined as a function of the area of input electrode when the area of output electrode is fixed. The effects of driving frequency and load resistance on the voltage step-down characteristics were also examined. Voltage gain was greatly dependent on the driving frequency and load resistance, and showed a maximum gain at resonance frequency of the step-down transformer. The frequency where the maximum output voltage appears increased about 0.2% as the load resistance increased from 10 to $150\Omega$. As the area of input electrode increased, the voltage gain and the efficiency of the transformer increased. Frequency dependence of efficiency of the step-down transformer revealed a similar tendency with the voltage gain curves. The maximum efficiency remarked 94% when the input voltage and the load resistance were 20 $V_{PP}$ and $120\Omega$, respectively.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
• /
• 2009.06a
• /
• pp.267-268
• /
• 2009

Resistance standards from 1 ${\Omega}$ to 100 $k{\Omega}$, with calculable frequency dependencies of up to 1 MHz, have been developed for the calibration of commercial inductance-capacitance-resistance (LCR) meters and impedance analyzers. The resistors are designed on the basis of single bifilar loops. The typical resistance change from dc to 1 MHz is from 200 to $800\;{\mu}{\Omega}/{\Omega}$. According to the measurement results, the frequency dependencies of the resistors are severaltimes lower than the measurement uncertainty of commercial LCR meters.

• Korean Journal of Veterinary Research
• /
• v.52 no.2
• /
• pp.133-139
• /
• 2012

Antimicrobial resistance is one of the most concerns in pig industry. Escherichia (E.) coli have been used for the indicator to monitor the antimicrobial resistance. In this study, 321 E. coli from diarrheic and non-diarrheic piglets were tested for antimicrobial resistance and frequency of $Bla_{TEM}$. In non-diarrheic piglets, they were resistant to oxytetracycline (93%), streptomycin (92%) and sulfadiazine (90%) but susceptible to ceftiofur (99%), colistin (97%), and enrofloxacin (82%). The isolates from diarrheic piglets were resistant to enrofloxacin (72.9%), ceftiofur (17.6%), and colistin (11.3%), whereas the resistance was 1%, 18% and 3% in case of non-diarrheic piglets, respectively. The resistance for amoxicillin/clavulanic acid (54.1%) and ceftiofur (22%) was high in isolates from post-weaning piglets. The resistance for colistin was 15.2% in nursery piglets. Seventy-three percent of isolates from diarrheic piglets showed high multidrug resistance profile (more than 13 antimicrobials) compared to those from non-diarrheic pigs in which 71% of isolates showed moderate multidrug resistance profile (7 to 12 antimicrobials). The frequency of $Bla_{TEM}$ in E. coli from non-diarrheic and diarrheic piglets was 57% and 69%, respectively. The results might provide the basic knowledge to establish the strategies for treatment and reduce antibiotic resistance of E. coli in piglets.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
• /
• v.23 no.7
• /
• pp.41-48
• /
• 2009

Grounding impedance depends on the frequency of current flowing into a grounding system lightning in particular has a broad frequency spectrum from some tens of Hz to a few MHz. So the grounding impedance related to transient currents such as lightning should be measured. In this paper, the grounding impedances of vertically-driven ground rods of 10, 30 and 48[m] long are measured and analyzed as functions of the frequency of injected current and the feeding point. As a result, the longer the ground rod is, the lower the steady-state ground resistance is. However the grounding impedance of a vertically-driven ground rod at a high frequency is significantly increased. It is not always true that low grounding impedance follows from a low steady-state ground resistance. It is important to evaluate the high frequency performance of grounding systems for protection against lightning.

• Journal of Korean Port Research
• /
• v.12 no.2
• /
• pp.323-328
• /
• 1998

A quartz crystal analyzer is utilized to monitor the corrosion process of an aluminum surface of a quartz crystal for marine sensor by sea water. A quartz crystal having 2000 $\AA$ of aluminum layer is installed in a specially designed cell and is in contact with sea water imitated electrolyte solution. While a constant potential is applied to the cell, the resonant frequency and resonant resistance are simultaneously measured using the quartz crystal analyzer. In addition, surface topographs are taken with an atomic force microscope(AFM) and the element analysis of the surface is conducted using an energy dispersive X-ray spectrometer(EDX). The simultaneous measurement of resonant frequency and resonant resistance during the corrosion process explains the change of surface structure caused by the corrosion. The variation of resonant frequency addresses the amount surface metal dissolution. As a conclusion, it is found that a simple measurement using the quartz crystal analyzer can replace the complex monitoring employing large equipments in the investigation of a corrosion process of sensor surface.

• Corrosion Science and Technology
• /
• v.20 no.5
• /
• pp.231-241
• /
• 2021

The objective of this study was to evaluate total current under steady-state conditions for a material undergoing corrosion using the electrochemical frequency modulation (EFM) technique, taking into account the presence of solution resistance and double layer capacitance. The analysis involving linearization of the Tafel curve allowed for the estimation of corrosion parameters. Results showed that the output signal was dependent on fundamental frequencies and their multiples. In addition, the output signal almost manifested itself at frequencies that were sums of fundamental frequencies of the applied sinusoidal signal. The harmonics calculated showed a significant shift from the principal frequency of input signals. The investigation involved the influence of corrosion current and anode-to-cathode Tafel slope ratio on faradaic and non-faradaic currents (including the average and RMS). The model presented showed both qualitative and quantitative improvements over the previously developed EFM technique that ignored the influence of solution resistance and the double layer capacitance while assuming the applied DC potential corresponded to the corrosion potential of the corroding material.

• Proceedings of the KSME Conference
• /
• 2000.04a
• /
• pp.67-72
• /
• 2000

Demand for now nondestructive evaluation are growing to detect fatigue crack growth behavior to predict long term performance of materials and structure in aggressive environments especially when they are In non-visible area. Acoustic emission technique is well suited to these problems and has drawn a keen interests because of its dynamic detection ability, extreme sensitivity and location of growing defects. In this study, we analysed acoustic emission signals obtained in fatigue and tensile test of high strength fire resistance steel for frame structure with time-frequency analysis methods. The main frequency range is different in the noise and the fatigue crack propagation. It could be classified that it were also generated by composite fracture mechanics of cleavage, dimple, inclusion separation etc.