• Genomics & Informatics
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• v.6 no.3
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• pp.99-109
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• 2008

Protein phosphorylation at tyrosine residues is a key regulatory event that modulates insulin signal transduction. We studied the PTPN1 gene with regard to susceptibility to Korean type 2 diabetes mellitus (T2DM) and its related quantitative traits. A total of seven SNPs [g.36171G>A (rs941798), g.58166G>A (rs3787343), g.58208A>G (rs2909270), g.64840C>T (rs754118), g.69560C>G (rs6020612), g.69866G>A (rs718050), and g.69934T>G (rs3787343)] were selected based on frequency (>0.05), linkage disequilibrium (LD) status, and haplotype tagging status. We studied the seven SNPs in 483 unrelated patients with type 2 diabetes (age: $64{\pm}2.8$ years, onset age: $56{\pm}8.1$ years; 206 men, 277 women) and 1138 nondiabetic control subjects (age: $64{\pm}2.9$; 516 men, 622 women). The SNP rs941798 had protective effects against T2DM with an odds ratio of 0.726 (C.I. $0.541{\sim}0.975$) and p-value=0.034, but none of the remaining six SNPs was associated with T2DM. Also, rs941798 was associated with blood pressure, HDL cholesterol, insulin sensitivity. rs941798 also has been associated with T2DM in previous reports of Caucasian-American and Hispanic-American populations. This is the first report that shows an association between PTPN1 and T2DM in the Korean as well as Asian population.

• Journal of the Korean Association of Geographic Information Studies
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• v.15 no.3
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• pp.119-136
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• 2012

The goal of this study is to apply the IPCC(Intergovernmental Panel on Climate Change) concept of vulnerability to climate change and verify the use of a combination of vulnerability index and fuzzy logic to flood vulnerability analysis and mapping in Seoul using GIS. In order to achieve this goal, this study identified indicators influencing floods based on literature review. We include indicators of exposure to climate(daily max rainfall, days of 80mm over), sensitivity(slope, geological, average DEM, impermeability layer, topography and drainage), and adaptive capacity(retarding basin and green-infra). Also, this research used fuzzy model for aggregating indicators, and utilized frequency ratio to decide fuzzy membership values. Results show that the number of days of precipitation above 80mm, the distance from river and impervious surface have comparatively strong influence on flood damage. Furthermore, when precipitation is over 269mm, areas with scare flood mitigation capacities, industrial land use, elevation of 16~20m, within 50m distance from rivers are quite vulnerable to floods. Yeongdeungpo-gu, Yongsan-gu, Mapo-gu include comparatively large vulnerable areas. This study improved previous flood vulnerability assessment methodology by adopting fuzzy model. Also, vulnerability map provides meaningful information for decision makers regarding priority areas for implementing flood mitigation policies.

• Nuclear Engineering and Technology
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• v.20 no.2
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• pp.88-104
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• 1988

The FUel Rod Analysis(FURA) code is developed using two-dimensional finite element methods for axisymmetric and plane stress analysis of fuel rod. It predicts the thermal and mechanical behavior of fuel rod during normal and load follow operations. To evaluate the exact temperature distribution and the inner gas pressure, the radial deformation of pellet and clad, the fission gas release are considered over the full-length of fuel rod. The thermal element equation is derived using Galerkin's techniques. The displacement element equation is derived using the principle of virtual works. The mechanical analysis can accommodate various components of strain: elastic, plastic, creep and thermal strain as well as strain due to swelling, relocation and densification. The 4-node quadratic isoparametric elements are adopted, and the geometric model is confined to a half-pellet-height region with the assumption that pellet-pellet interaction is symmetrical. The pellet cracking and crack healing, pellet-cladding interaction are modelled. The Newton-Raphson iteration with an implicit algorithm is applied to perform the analysis of non-linear material behavior accurately and stably. The pellet and cladding model has been compared with both analytical solutions and experimental results. The observed and predicted results are in good agreement. The general behavior of fuel rod is calculated by axisymmetric system and the cladding behavior against radial crack is used by plane stress system. The sensitivity of strain aging of PWR fuel cladding tube due to load following is evaluated in terms of linear power, load cycle frequency and amplitude.

• The Korean Journal of Pesticide Science
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• v.15 no.1
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• pp.48-54
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• 2011

Risk assessments of pesticides detected in six major rivers during peak season were estimated for algae, Daphnia, and fish using hazard quotient (HQ) indexes. The eight pesticides (isoprothiolane, hexaconazole, diazinon, chlorpyrifos, prothiofos, alachlor, butachlor, molinate) were detected within the range of 0.027~12.871 ${\mu}g/L$. Detection frequency of isoprothiolate was estimated to be high at 67.5%, and those of the others varied from 15.0 to 37.5%, Hazard Quotients (HQ) indexes varied by freshwater organisms (algae, Daphnia, and fish). Overall, the ecological risk probability due to exposure of pesticides detected in major rivers did not reveal based on HQ indexes below 1.0. Particularly, butachlor and molinate for algae, chlorpyrifos, diazinon, prothiofos for Daphnia, and chlorpyrifos for fish acted as dominant contributors in increasing the ecological risk in six major rivers. This implied that integrated ecological risk assessment is required using various biological species, reflecting toxicity sensitivity. This study may provide the essential data in establishing the priority for pesticides management in major rivers, Korea.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2010.05a
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• pp.535-539
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• 2010

This paper include to study DoA(Direction of Arrival) for radio collection and monitoring system. The direction finding calculated by applying the CVDF (Correlation Vector Direction Finding) algorithm for the five circular dipole antenna over V / UHF band. To improve the accuracy of direction finding by applying CVDF algorithm needs to obtain ideal phase difference each antennas. However, a circular array antenna phase difference pattern may be distorted on a specific frequency band or to particular direction. The effect of installing each array antennas circularly and the effect of the interference of center pole (located in the center of a circular array antenna mount) may make the distortion of phase pattern. If you use an active antenna instead of passive antenna to obtain good sensitivity, you would measure the more distortion. This paper propose how to change combination of antennas to measure the phase in real-time and how to use antenna beam patterns for minimizing the degradation phenomena at applying simple CVDF algorithm and increasing the direction finding capability.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.2
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• pp.989-999
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• 2014

The purpose of this study was to identify the influencing health promoting behavior of perceived health status and self-efficacy according to major of college students to develop health promoting interventions of college students. The subjects of this study were 592 college students in C city in Korea. Health promoting behavior was significantly higher(p=.014) in health related major students than none health related major students. There were significantly difference in "an time to school(p=.007)", "sleeping hours(p=.004)", "drinking(p=0.028)", "exercise(p<.001)", "exercise frequency(p=.012)" between health related major and none health related major. perceived health status(r=0.381, p<.001) and self efficacy(r=0.620, p<.001) were significantly positive relation to health promoting behavior. The other sub factor in self efficacy were confidence(p<.001), effort(p=.008), will(p=.001) and sub factor in perceived health status were present health(p<.001), health anxiety(p=.002), resistibility and sensitivity(p=.002) in none health related major students($R^2$=0.432, F=38.620). We suggested that the results of this study be considered in developing health promoting programs through appropriate education and various activity of young adults.

• Korean Journal of Optics and Photonics
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• v.2 no.3
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• pp.139-148
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• 1991

A fiber-optic magnetic sensor system for the detection of small ac magnetic field(200Hz-2 kHz) was constructed. Magnetic field sensing part was fabricated by bonding a section of optical fiber to amorphous metallic glass(2605SC) having large magnetostriction effect. And with the directional coupler, all fiber type Mach-Zehnder interferometer was constructed to measure the variation of the external magnetic field by translating it into the optical phase shift in the interferometer. The signal fading problem of the interferometer, which is due to random phase drifts originated from the environment, i.e., temperature fluctuation, vibrations, etc., was elliminated by feedback phase compensation. This allows the sensitivity to be maintained at the maximum by keeping the interferometer in quadrature phase condition. The frequency response of metallic glass was found to be nearly flat in the range of 90 Hz-2 kHz and dc bias field for the maximum ac response was 3.5 Oe. The interferometer output showed good linearity over the range $\pm$0.5 Oe. For 1 kHz ac magnetic field the scale factor S and the minimum detectable magnetic field were measured to be 8.0 rad/Oe and $3X10^{-6} Oe/\sqrt{Hz}$at 1 Hz detection bandwidth respectively.

• Journal of Korean Society of Forest Science
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• v.25 no.1
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• pp.80-84
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• 1975

The seeds, scions and plants of chestnut tree (Castanea. crenata) and Chinese chestnut tree (C. bungeana) were irradiated by gamma ray in order to know their biological effects on germination, plant growth and mutation at several accumulative doses and dose rates. The results of this study could be summarized as follows: 1. In general, the radio-sensitivity of scions was more sensitive to irradiation, showing 50% reduction dose of the control for grafting percentage at 3.1 kR as compared with 4.6 kR for the above reduction dose in germination rates of seeds. 2. The seeds treated by 5 kR dose resulted in some albino mutants at a rate of 0.84%. There was a general tendency that the seedling height reduced significantly as the irradiation dose increased. 3. The scions treated by an acute irradiation showed their 50% reduction dose in grafting at 3.2 kR for Chinese chestnut and at 3.1 kR for chestnut, respectively, while their irradiation doses increased three times, having 10.2 kR for the 50% reduction dose in the case of semi-acute irradiation. 4. When Chinese chestnut trees were irradiated during their dormant period with a total dose of 7.5 kR to 4.9 kR at a dose rate of 150 R to 98 R per day, there were induced giant leaf bud-sports at a frequency of 16.6%. The averag leaf area of the giant leaf bud-sports were measured at 96.36 square centimeters, while the area of normal leaf was only 26.28 square centimeters.

• Journal of the Korea Society for Simulation
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• v.28 no.2
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• pp.1-14
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• 2019

A full scale hydrodynamic simulation that requires an accurate reproduction of shock-induced detonation was conducted for design of an energetic component system. A detailed hydrodynamic analysis SW was developed to validate the reactive flow model for predicting the shock propagation in a train configuration and to quantify the shock sensitivity of the energetic materials. The pyrotechnic device is composed of four main components, namely a donor unit (HNS+HMX), a bulkhead (STS), an acceptor explosive (RDX), and a propellant (BPN) for gas generation. The pressurized gases generated from the burning propellant were purged into a 10 cc release chamber for study of the inherent oscillatory flow induced by the interferences between shock and rarefaction waves. The pressure fluctuations measured from experiment and calculation were investigated to further validate the peculiar peak at specific characteristic frequency (${\omega}_c=8.3kHz$). In this paper, a step-by-step numerical description of detonation of high explosive components, deflagration of propellant component, and deformation of metal component is given in order to facilitate the proper implementation of the outlined formulation into a shock physics code for a full scale hydrodynamic simulation of the energetic component system.

• Journal of Korea Entertainment Industry Association
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• v.14 no.4
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• pp.199-209
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• 2020

"Positive Influence(PI)" of popular star has recently emerged as a social concern, but the lack of prior research has led to confusion over its concept and range of activity. On this point, this study carried out to lay the groundwork for discussions on the systematization of related theories, focused on identifying the current situations by analyzing articles for 15 months from January 2019 to March 2020 when related reports were in full swing. As a result of the analysis of the remarks from the entertainers mentioned in the articles, they were not clearly aware of the concept while doing good deeds under the name of PI in light of the study outcome by Aegean and Singer(2013). The motivations for good deed were classified into six types, including difficulty empathy, fandom reward, participation urge, nidana emphasis, experience subjugation, and memory evocation in the order of frequency of cases. Specific behaviors of PI were followed by donations of money and valuables for 54.4 percent, participation of social agendas for 14.0 percent, volunteering for 13.2 percent, joining campaign for 11.4 percent, other good deeds for 4.0 percent, and philanthropy for 3.0 percent. In occupational analysis, the concentration of donations was also evident. Their activities in the fields of human rights sensitivity, environmental protection and self-management, which are expected to have great effects with their influence, have been extremely poor. The results of the study first require academia to establish a interdisciplinary concept for PI. It also suggests that entertainers and their agencies should take far more strategic approach to evolve the PI event in a way that utilizes the advantages of each job group, such as actors, singers and comedians, and expands the diversity of areas.