• Title/Summary/Keyword: Frequency Response Model

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Effect of Twice Daily Administration of GH-releasing Peptide-2 for 10 Days on Growth Performance, Plasma GH Responses and Insulin-like Growth Factor-1 Concentrations in Swine

  • Nou, V.;Inoue, H.;Lee, H.G.;Matsunaga, N.;Kuwayama, H.;Hidari, H.
    • Asian-Australasian Journal of Animal Sciences
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    • v.16 no.8
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    • pp.1193-1198
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    • 2003
  • An increase in frequency of administration of exogenous growth hormone (GH) or GH-releasing hormone was reported to be a model to increase blood circulating insulin-like growth factor-1 (IGF-1) and to improve growth performance in animals. We have investigated the effect of twice daily administration of GH-releasing peptide-2 (GHRP-2) on growth performance, GH responsiveness and plasma insulin-like growth factor IGF-1 in swine. We administered to eight swine, 3 control and 5 treatment, a twice daily s.c. injections of GHRP-2 ($30{\mu}g/kg\;BW$) for a period of 10 days. Every day blood samples immediately taken before injections of GHRP-2 or saline, at 08:00 h and 16:00 h, were measured for IGF-1 concentrations. Blood samples for GH assay were collected every 20 min on days 1, 6 and 10, from 1 hour before and 3 h after GHRP-2 or saline injections at 08:00 h. GH peak concentrations and GH area under curve (GH AUC) on day 1, 6 and 10 in treatment group of swine were higher than those in control swine (p<0.05). Twice daily administration of GHRP-2 caused a significantly attenuation (p<0.05) of GH peak concentrations ($80.25{\pm}13.87$, $39.73{\pm}5.72$ and $27.57{\pm}6.06ng/ml$ for day 1, 6 and 10, respectively) and GH AUCs ($3,536.15{\pm}738.35$, $1,310.31{\pm}203.55$ and $934.37{\pm}208.99ng/ml$ for day 1, 6 and 10, respectively). However, there was no significant difference in GH peak concentration and GH AUC between day 6 and 10. Plasma IGF-1 concentration levels were higher in treatment than control group of swine (p<0.05) after 3 days of the treatment, and the levels reached a plateau from day 3 to 10 of experiment. Growth performance did not alter by GHRP-2 administration, even though a numerical increase of body weight gain and feed efficiency was observed. These results indicate that twice daily administration of GHRP-2 for 10 days in swine did not significantly influence on growth performance, caused an overall attenuation of GH response, and that elevation of plasma GH concentrations caused by GHRP-2 administration increased plasma IGF-1 concentrations, even though an attenuation of GH response was observed.

An Application of loop-loop EM Method for Geotechnical Survey (지반조사를 위한 loop-loop 전자탐사 기법의 적용)

  • You Jin-Sang;Song Yoonho;Seo1 Soon-Jee;Song Young-Soo
    • Geophysics and Geophysical Exploration
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    • v.4 no.2
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    • pp.25-33
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    • 2001
  • Loop-loop electromagnetic (EM) survey in frequency domain has been carried out in order to provide basic solution to geotechnical applications. Source and receiver configuration may be horizontal co-planar (HCP) and/or vertical co-planar (VCP). Three quadrature components of mutual impedance ratio for each configuration are used to construct the subsurface image. For the purpose of obtaining the model response and validating the reasonable performance of the inversion, we obtained each responses of two-layered and three-layered earth models and two-dimensional (2-D) isolated anomalous body. The response of 2-D isolated anomalous body has been calculated using extended Born approximation for the solution of 2.5-D integral equation describing EM scattering problem. As a result of the least-squares inversion with variable Lagrangian multiplier, we could construct more resolvable image from HCP data than VCP data. Furthermore, joint inversion of HCP and VCP data made better stability and resolution of the inversion. Resistivity values, however, did not exactly match the true ones. Loop-loop EM field data was obtained with EM34-3XL system manufactured by Geonics Ltd. (Canada). Electrical resistivity survey was conducted on the same line for the comparison in advance. Since the constructed image from loop-loop EM data by 2-D inversion algorithm showed almost similar resistivity distribution to that from electrical resistivity one, we expect the developed 2.5-D loop-loop EM inversion program can be applied for the reconnaissance site survey.

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Combined Effects of Different Wavelength Laser Stimulations and Electroacupuncture on Neuropathic Pain (파장별 레이저 자극과 전침 결합 시술이 신경병리성 동통에 미치는 영향)

  • Cho, Myoung-rae;Kim, Myeong-hun;Moon, Youngmin;Jeong, Sungho;Na, Chang-su
    • Korean Journal of Acupuncture
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    • v.38 no.3
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    • pp.151-161
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    • 2021
  • Objectives : The effects of a combined stimulation of 658 nm, 830 nm, 904 nm, and 1064 nm laser acupuncture treatment (LAT) and electroacupuncture treatment (EAT) on GB39 and GB34 on neuropathic pain in rats induced by tibial and sural nerve transection were studied in this paper. Methods : To express a neuropathic pain model, surgery was performed to transection rats' tibial and sural nerves. The rats were divided into normal group, control group, and experimental groups. In addition, the experimental groups were divided into 658 nm laser and electroacupuncture (LAT658+EAT), 830 nm laser and electroacupuncture (LAT830+EAT), 904 nm laser and electroacupuncture (LAT904+EAT), and 1064 nm laser and electroacupuncture (LAT830+EAT). For the treatment of the experimental groups, electroacupuncture and different laser wavelengths were alternately applied to GB34 and GB39 twice a week for 3 weeks for 1 minute 30 seconds. The withdrawal response of neuropathic rats' legs by acetone stimulation was observed, as well as the c-Fos in the central gray region in the midbrain of neuropathic rats together with Bax, Bcl2, and mGluR5 expressions associated with apoptosis. Results : Compared with the control group, a significant decrease in the frequency of paw withdrawal in response to acetone allodynia was observed in LAT658+EAT and LAT830+EAT groups in 6th times, LAT904+EAT group in 2nd, 3rd, and 6th times, and LAT1064+EAT group in 2nd and 6th times, respectively. For c-fos positive cells in the central gray region, a significant decrease was observed in LAT830+EAT, LAT904+EAT, and LAT1064+EAT groups in comparison with the control group. In Bax expression, LAT1064+EAT group showed a significant decrease compared to the control group. In Bcl-2 expression, the LAT658+EAT,the LAT904+EAT, and the LAT1064+EAT groups increased significantly compared to the control group. LAT830+EAT, LAT904+EAT, and LAT1064+EAT groups showed significantly increased mGlu5 expression compared to the control group. Conclusions : The combination of laser for each wavelength and electroacupuncture alternately performed in this study is thought to be effective in improving neuropathic pain and apoptosis.

Vitalization of Ecological, Scenic, Participative aspects of Urban Agriculture - Focusing on Population Characteristics and Individual Recognitions - (생태, 경관, 참여 측면의 도시농업 활성화 방안 모색 - 인구집단 특성과 개인의 주관적 인식 분석을 중심으로 -)

  • Chang, Insu;Suh, Tongju;Kim, Hong sok(Brian)
    • Journal of the Korean Regional Science Association
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    • v.34 no.4
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    • pp.35-48
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    • 2018
  • The purpose of this study is to empirically investigate the experiences and subjective opinions of urban agriculture in order to explore ways to vitalize urban agriculture. More specifically, we divides environmental value into three categories of ecology, landscape, and participation, and defines a function of urban agriculture to improve environmental values related to the three categories mentioned above. The main results of the empirical analysis using the survey data are summarized as follows. First, the probability of gathering information about urban agriculture is higher in metropolitan cities than small cities, and the larger the residence size, the higher the probability of actual urban agriculture participation. Second, the positive response rate was high for the three categories of urban agriculture, while the negative response rate was high for the surrounding environment. The implications derived from the analysis are as follows. First, the opposite results of experiences of urban agriculture suggests that local governments should further promote urban agriculture-based investment policies. In addition, these policies need to be preceded by analysis of the characteristics of population groups in the region Also, it is necessary to improve the environment through urban agriculture.

Development Strategy of Smart Urban Flood Management System based on High-Resolution Hydrologic Radar (고정밀 수문레이더 기반 스마트 도시홍수 관리시스템 개발방안)

  • YU, Wan-Sik;HWANG, Eui-Ho;CHAE, Hyo-Sok;KIM, Dae-Sun
    • Journal of the Korean Association of Geographic Information Studies
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    • v.21 no.4
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    • pp.191-201
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    • 2018
  • Recently, the frequency of heavy rainfall is increasing due to the effects of climate change, and heavy rainfall in urban areas has an unexpected and local characteristic. Floods caused by localized heavy rains in urban areas occur rapidly and frequently, so that life and property damage is also increasing. It is crucial how fast and precise observations can be made on successful flood management in urban areas. Local heavy rainfall is predominant in low-level storms, and the present large-scale radars are vulnerable to low-level rainfall detection and observations. Therefore, it is necessary to introduce a new urban flood forecasting system to minimize urban flood damage by upgrading the urban flood response system and improving observation and forecasting accuracy by quickly observing and predicting the local storm in urban areas. Currently, the WHAP (Water Hazard Information Platform) Project is promoting the goal of securing new concept water disaster response technology by linking high resolution hydrological information with rainfall prediction and urban flood model. In the WHAP Project, local rainfall detection and prediction, urban flood prediction and operation technology are being developed based on high-resolution small radar for observing the local rainfall. This study is expected to provide more accurate and detailed urban flood warning system by enabling high-resolution observation of urban areas.

An Analysis of the Support Policy for Small Businesses in the Post-Covid-19 Era Using the LDA Topic Model (LDA 토픽 모델을 활용한 포스트 Covid-19 시대의 소상공인 지원정책 분석)

  • Kyung-Do Suh;Jung-il Choi;Pan-Am Choi;Jaerim Jung
    • Journal of Industrial Convergence
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    • v.22 no.6
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    • pp.51-59
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    • 2024
  • The purpose of the paper is to suggest government policies that are practically helpful to small business owners in pandemic situations such as COVID-19. To this end, keyword frequency analysis and word cloud analysis of text mining analysis were performed by crawling news articles centered on the keywords "COVID-19 Support for Small Businesses", "The Impact of Small Businesses by Response System to COVID-19 Infectious Diseases", and "COVID-19 Small Business Economic Policy", and major issues were identified through LDA topic modeling analysis. As a result of conducting LDA topic modeling, the support policy for small business owners formed a topic label with government cash and financial support, and the impact of small business owners according to the COVID-19 infectious disease response system formed a topic label with a government-led quarantine system and an individual-led quarantine system, and the COVID-19 economic policy formed a topic label with a policy for small business owners to acquire economic crisis and self-sustainability. Focusing on the organized topic label, it was intended to provide basic data for small business owners to understand the damage reduction policy for small business owners and the policy for enhancing market competitiveness in the future pandemic situation.

Study on Climate Change Impacts on Hydrological Response using a SWAT model in the Xe Bang Fai River Basin, Lao People's Democratic Republic (기후변화에 따른 라오스인민공화국의 시방파이 유역의 수문현상 예측에 대한 연구: SWAT 모델을 이용하여)

  • Phomsouvanh, Virasith;Phetpaseuth, Vannaphone;Park, Soo Jin
    • Journal of the Korean Geographical Society
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    • v.51 no.6
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    • pp.779-797
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    • 2016
  • A calibrated hydrological model is a useful tool for quantifying the impacts of the climate variations and land use/land cover changes on sediment load, water quality and runoff. In the rainy season each year, the Xe Bang Fai river basin is provisionally flooded because of typhoons, the frequency and intensity of which are sensitive to ongoing climate change. Severe heavy rainfall has continuously occurred in this basin area, often causing severe floods at downstream of the Xe Bang Fai river basin. The main purpose of this study is to investigate the climate change impact on river discharge using a Soil and Water Assessment Tool (SWAT) model based on future climate change scenarios. In this study, the simulation of hydrological river discharge is used by SWAT model, covering a total area of $10,064km^2$ in the central part of country. The hydrological model (baseline) is calibrated and validated for two periods: 2001-2005 and 2006-2010, respectively. The monthly simulation outcomes during the calibration and validation model are good results with $R^2$ > 0.9 and ENS > 0.9. Because of ongoing climate change, three climate models (IPSL CM5A-MR 2030, GISS E2-R-CC 2030 and GFDL CM3 2030) indicate that the rainfall in this area is likely to increase up to 10% during the summer monsoon season in the near future, year 2030. As a result of these precipitation increases, the SWAT model predicts rainy season (Jul-Aug-Sep) river discharge at the Xebangfai@bridge station will be about $800m^3/s$ larger than the present. This calibrated model is expected to contribute for preventing flood disaster risk and sustainable development of Laos

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Prediction of EFT/B Signal Transfer Characteristics in Mobile Charging Circuit (모바일 충전회로에서 EFT/B 신호의 전달특성 예측에 대한 연구)

  • Song, SeungJae;Kim, Kwangho;Jo, Jeongmin;Lee, Seungbae;Kim, So-young;Nah, Wansoo
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.26 no.10
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    • pp.895-906
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    • 2015
  • This paper presents a methodology and a model that can analyze the high frequency transfer characteristics from socket in the AC power port to the 5 V DC output port in the mobile charging circuit. This is to predict the output signals coming from the IEC(International Electrotechnical Commission) Standard(IEC 61000-4-4), EFT/B(Electric Fast Transient and Burst) immunity test for mobile charging circuit. Since the mobile charging circuit is energized from the AC power socket from the power line, it is necessary to know the high frequency transfer characteristics with activated AC power line. A simple CDN(Coupling-Decoupling Network) is designed and manufactured for measuring S-parameters of mobile charging circuit with and without AC power line activated. The result shows that the S-parameters of the specific mobile charging circuits are almost the same, independent of AC power line activation. Consequently, the S-parameters without AC line could be used to predict the output response to the EFT/B signals, and it was shown that the proposed methodology predicts the output responses quite accurately, which proves the validness of the methodology presented in this paper.

Estimation of Dynamic Displacement and Characteristics of A Simple Beam from FBG Sensor Signals (FBG센서 응답을 이용한 단순보의 동적 변위 및 동특성 추정)

  • Choi, Eun Soo;Kang, Dong Hoon;Chung, Won Seok;Kim, Hak Soo
    • Journal of Korean Society of Steel Construction
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    • v.18 no.4
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    • pp.503-514
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    • 2006
  • FBG sensors are capable of measuring the strain of structures easily and more durably than electric resistance gauges. Thus, many researches are dedicated to the application for the response monitoring or non-destructive evaluation of structures using FBG sensors. Additionally, the measured strains at the top and bottom of a cross-section can be transformed into the curvature of the section, which can be used to calculate its vertical displacement. Hence, this study aims to measure the dynamic strain signals of a steel section simply supported beam and to estimate the dynamic displacement from the strain signals, after which the estimated displacement is com pared with the measured displacement. The dynamic characteristics (natural frequency, damping ratio and mode shape) of the beam are predicted from both the estimated and measured displacement signals, and from the strain time history of the FBG sensors. The predicted properties are compared with those of an analytical model of the beam. The estimated displacement. However, the predicted dynamic properties from both the estimated displacements and the measured strains are well-correlated with those from the measured displacement. It is therefore appreciated that the estimation of the dynamic properties of FBG sensor signals is reasonable. Especially, the strain signal of the FBG sensor was amplified at a higher-frequency region in comparison with the displacement estimation with higher-mode properties.

Dynamic Behavior of the Prestressed Composite Girder by Modal Tests and Moving Train Analysis (프리스트레스트 강합성 거더의 모달테스트 및 이동 열차하중 해석에 의한 동적거동)

  • Kim, Sung Il;Lee, Pil Goo;Lee, Jung Whee;Yeo, In Ho
    • Journal of Korean Society of Steel Construction
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    • v.18 no.6
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    • pp.793-804
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    • 2006
  • Various PSC and steel-concrete composite railway bridges are being developed for short-medium spans with structural and economic efficiency. According to the design concept, the prestressed composite girder bridge has the advantages of being lightweight and having low girder depth, with the capacity for long spans. However, the dynamic behavior under a passing train is one of the critical issues concerning these railway bridges designed with more flexibility. Therefore, it is very important to evaluate the modal parameters before performing dynamic analyses. In this paper, real-scale prestressed composite girders were fabricated as a test model and modal testing was carried out to evaluate modal parameters including natural frequency and modal damping ratio. During the modal testing, a digitally controlled vibration exciter as well as an impact hammer was applied to obtain frequency-response functions, and the modal parameters were also evaluated after the fracture of test models. With application of reliable properties from modal tests, the estimation of dynamic performances of prestressed composite girder railway bridges can be obtained from various parametric studies on dynamic behavior under the passage of a moving train.