• 한국식품위생안전성학회지
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• 제39권4호
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• pp.299-303
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• 2024

최근 국내외 화장품과 식품산업에서 다양하게 사용되어지고 있는 콜라겐 단백질 제품은 점차 그 용도와 특성에 따라 보다 고도화, 기능화 되어 가고 있다. 피부 건강의 지표인 콜라겐은 다양한 용도로 개발되어 사용되고 있으며, 콜라겐의 소비가 증가함에 따라 용도에 적합한 최적화된 콜라겐 제품의 개발이 중요한 연구 분야이다. 특히 여러 기업과 연구기관들에 의해서 콜라겐의 흡수율을 높이기 위한 다양한 노력이 이루어지고 있다. 따라서 본 연구에서는 프란즈(Franz) 세포 시스템을 이용하여 국내에서 판매되는 다양한 분자량별 콜라겐 제품의 경피 및 구강상피세포 투과성을 비교하였다. 그 결과, 피부 표피/진피 조직과 비교하여 구강점막 조직의 콜라겐 흡수율이 분자량 500달톤과 1,000달톤의 경우 모두 통계적으로 유의하게(각각 약 10배, 2배) 높은 것으로 확인되었다. 또한, 분자량별 구강점막 조직 흡수율을 비교한 결과, 분자량 500달톤의 콜라겐이 분자량 1,000달톤 제품에 비해 흡수율이 2-3배 증가함을 확인하였다. 분자량 500달톤의 경우 Cmax와 AUCt 값이 가장 높게 나타났으며, 피부 표피/진피 세포에 비해 구강점막세포 시험군의 모든 지표가 높은 것으로 나타났다. 본 연구 결과는 피부 흡수보다는 구강 점막 세포를 통한 콜라겐의 흡수방법이 콜라겐 체내 흡수증가에 유효한 수단임을 시사하며, 분자량 1,000달톤 이하에서도 보다 더 작은 500달톤의 저분자 콜라겐의 흡수율이 증가되는 것으로 보아 콜라겐의 분자량이 흡수율 증가의 주요한 요소임을 확인할 수 있었다.

• 동서간호학연구지
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• 제13권2호
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• pp.130-137
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• 2007

Purpose: This study aimed to identify the safety perception and behaviors of mothers with school age children. Method: The subjects were 265 mothers of third graders in one elementary school located in metropolitan Seoul area. Framingham safety survey were used to guide the development of a self administered questionnaire for mothers. The questionnaire were sent home at school and the children returned them to their class teachers. Results: Among 265 mothers, 62 mothers (23.4%) had experience of visiting hospitals because of accidents and 201 mothers (75.8%) had no opportunities on safety education. Mothers with education higher than high school graduation showed more safety behaviors. Also, mothers having the experience of safety education showed higher scores on safety behaviors and mothers with the experience of hospital visits related to accidents showed low scores on safety behaviors. In the practice of safety behaviors, it showed high score to the traffic safety, followed by the home safety, child supervision, the safety from fire and explosion, the safety from electric devices, the safety from burn, and the safety from medicines. Conclusion: Mothers' overall practice on safety were poor. Based on these results, it is necessary to provide more safety education for mothers with school age children.

• 성인간호학회지
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• 제19권1호
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• pp.132-143
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• 2007

Purpose: The purpose of this study was to identify effects of a self-management program on symptom and functional status, health perception, and quality of life(QOL) of patients with CHF. Methods: Patients with CHF as defined through clinical judgment using the Framingham criteria and EF<50% were enrolled in the study (experimental: 21, control: 20). The symptom focused self-management program consisted of coping behaviors for symptoms including dyspnea, chest discomfort/pain, dizziness, ankle edema, and basic self-management including medications, diets, activity, lifestyle changes. Experimental group received an educational booklet after survey, and periodic telephone follow-up by a trained nurse. Data were collected the 3rd day after admission and at 1 month, 3 months, and 6 months after discharge using questionnaires. Results: Significant differences were found in the presence of symptoms, health perception, and QOL between groups during follow-up. Although no significant difference was found in functional status, the experimental group reported better functional status than the control group. Conclusion: By facilitating self-management of CHF using tailored interventions including education programs and telephone monitoring, it is expected that patients will be able to monitor their symptoms routinely, adhere to therapeutic regimen, and have a better QOL.

• Journal of Korean Biological Nursing Science
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• 제10권2호
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• pp.121-130
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• 2008

Purpose: This study was undertaken to identify stroke risk with risk factors and knowledge of stork in women with prehypertension. Methods: A total of 46 pre-hypertensive women in urban area aged 44.8 (SD 11.4) yr old in average were selected by a convenient sampling. Demographic data, risk factors, and knowledge of stroke were assessed through face to face interview. Stroke risk scores were calculated based on points given to age, systolic blood pressure, smoking, DM, and heart disease in Framingham stroke risk score. Data were analyzed by SPSS WIN 12.0 using descriptive statistics, two sample t-test, and Pearson's correlation coefficient. Results: The mean systolic blood pressure of participants was 133.11 mmHg, and HDL cholesterol was lower than the recommended level, although rest of physiologic risk factors were within normal. Of the participants, 82% did not do regular physical activity and 75% did not control fat intake persistently. Mean stroke risk points and knowledge scores were 4.48 and 29.15, respectively, which were significantly different between women with and without persistent controlling fat intake. Conclusion: Results indicate stroke prevention intervention for prehypertensive women should address comprehensively modifying lifestyle as well as physiologic factors, and information focusing on stroke risk factors and warning symptoms.

• 성인간호학회지
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• 제20권1호
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• pp.102-112
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• 2008

Purpose: The purpose of this study was to examine self care behaviors according to the risk levels of vascular complications in elderly women with hypertension. Methods: The subjects of this study were 162 women living in the community who had been diagnosed with hypertension in clinics. The data were analysed by the SPSS 10.0 program using descriptive statistics, t-test, and ANOVA with Scheff$\dot{e}$ post-hoc test. Results: The average self care behavior score of the elderly women was 2.79. Total self care behavior was significantly different depending on the risk levels of vascular complications such as systolic blood pressure, diastolic blood pressure, ankle-brachial index, and the framingham point score. Among sub-scores of self care behaviors, exercise management was the poorest performance compared with other self care behaviors. Conclusion: This study proved the differences in self care behaviors according to the risk levels of vascular complications. To decrease the prevalence of vascular complication, it is necessary to develop programs specifically to enhance self care behaviors of elderly women with hypertension.

• 보건교육건강증진학회지
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• 제32권5호
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• pp.73-81
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• 2015

Objectives: We tried to confirm physical activity of 1,000 Kcal per week was a meaningful point in controlling coronary artery disease risks in female older adults. Methods: Participants were 66 female older adults recruited from senior welfare center. Participants were provided with accelerometer (e-step, Kenz, Japan) for measuring daily energy expenditure. Graded exercise test was done for measuring aerobic fitness. Blood glucose and lipid were analyzed. Framingham risk score was calculated based on blood glucose, blood lipid, and smoking. These variables were compared between the group expended more than 1,000 Kcal/week and the group with energy expenditure below 1,000 Kcal/week. Results: The group expended over 1,000kcal/week showed to be superior to the counterpart group in following variables; AC(Abdominal Circumference), %BF, $HR_{rest}$(resting heart rate), $VO_{2peak}$, FBG, LDL-C, TG, BDI-II, QOL, AR(Absolute Risk), RR(Relative Risk). Conclusions: The group expended over 1,000 Kcal/week was likely to have less probability in CAD than group expended less than 1,000 Kcal/week. The result of this study suggests the important role of active daily life that can be replaced with that of regular exercise especially for those who are not available to do structured exercise.

• 기본간호학회지
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• 제21권2호
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• pp.174-182
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• 2014

Purpose: This study was done to investigate the probability of stroke, knowledge of stroke, and health-promoting lifestyle among stroke risk groups. Method: A descriptive correlational design was used. Data for 110 patients were analyzed. The probability of stroke was calculated using the Stroke Risk Profile from the Framingham Heart Study (2013), knowledge of stroke was measured using a questionnaire developed by Yoon et al. (2001), and health-promoting lifestyle was measured using the HPLP-II, developed by Walker et al. (1995). Results: The average probability of stroke was 11.74, knowledge of stroke, 67.88, and health-promoting lifestyle, 2.27. Probability of stroke showed significant differences according to gender. Knowledge differed according to patients' salaries. Health-promoting lifestyle showed significant differences according to gender. There were no significant correlations between probability of stroke and knowledge of stroke or probability of stroke and health-promoting lifestyle, but there was a significant correlation between knowledge of stroke and health-promoting lifestyle. Conclusion: Results indicate the necessity of active education to increase knowledge related to stroke which will contribute to an increase in health-promoting behaviors and make primary prevention a reality in the reduction of risk of stroke among stroke risk groups.

• Journal of Korean Biological Nursing Science
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• 제21권2호
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• pp.123-132
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• 2019

Purpose: The purpose of this study was to identify influencing factors of metabolic index and cardiovascular risk factors, on depressive and non-depressive groups, in vulnerable diabetic elderly women. Methods: Participants were 137 vulnerable diabetic elderly women, using health centers in D city. Data were collected through interviews September though December 2017. The metabolic index was measured using National Cholesterol Education Program-Adult Treatment Panel III (NCEP-ATP III), and cardiovascular risk factors were measured using Framingham Risk Score (FRS). Depressive and non-depressive groups were divided by the score of Geriartric Depress Scale Short Korea Version (GDSSF). Collected data were analyzed using a x2 test, independent t-test, and binary logistic regression, with the SPSS/WIN 25.0 program. Results: Vulnerable diabetic elderly women, did not exercise in the depressive groups, and had higher triglyceride (TG), total cholesterol (TC) and larger waists, than in the non-depressive group. Results show that lack of exercise (OR= 6.30), is the highest risk factor, influencing the depressive symptom in vulnerable diabetic elderly women. Conclusion: These results suggest that to reduce depressive symptom levels among vulnerable diabetic elderly women, nursing interventions are needed to increase exercise and decrease TG, TC, and waist size, particularly in improving exercise of vulnerable diabetic elderly women.

• 성인간호학회지
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• 제25권5호
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• pp.515-526
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• 2013

Purpose: The study aims to evaluate the effects of Tai Chi applied cardiac rehabilitation program(TCCRP) on cardiovascular risks, recurrence risk in ten years, and cardiac specific quality of life in individuals with coronary artery disease. Methods: The sample was comprised of individuals diagnosed with coronary artery disease within six months of the study who were referred by their primary physicians to participate in the TCCRP. The design was a pretest/posttest with non-equivalent groups with 30 in TCCRP program and 33 wait-listed comparison group. Results: The average age of all participants was sixty seven years. At the completion of the TCCRP, the Tai Chi group showed significant reduction in their ten year recurrent risk for coronary artery disease measured by Framingham's algorithm. The quality of life for the experimental group was reported as significantly higher than the comparison group, especially the area of general symptom. Conclusion: The outpatient cardiac rehabilitation with Tai Chi was applied effectively and safely without any complication to individuals with coronary artery disease. Tai Chi can be useful as an alternative exercise for cardiac rehabilitation program which may provide more access to individuals for cardiovascular risk management in the community settings.

• 동의신경정신과학회지
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• 제22권2호
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• pp.27-37
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• 2011

Objectives : The purpose of this research is to investigate the corelationship between Hwa-Byung and type A behavior pattern (TABP), cardiovascular disease. Methods : 637 people participated in the community based cohort study in Wonju City of South Korea from July 2nd to August 30th in 2006. Educated investigators checked up EKG and surveyed Hwa-Byung Diagnostic Interview Schedule(HBDIS), Framingham Type A Pattern Score(FTA score). Collected data were analyzed by the chi-square test & t-test. Results : 1. TABP, Hwa-Byung group was 24(70.6%), non Hwa-Byung group was 288(27.8%) p-value was 0.016. Difference of the two group was valid. 2. FTA score, Hwa-Byung group was $5.77{\pm}2.25$, non Hwa-Byung group was $4.41{\pm}2.30$, p-value was 0.002. Difference of the two group was valid. Conclusions : TABP ratio, FTA score was high in Hwa-Byung group compared with non Hwa-Byung group.