• Journal of Korean Medical classics
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• v.28 no.4
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• pp.1-9
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• 2015

Objectives : The main aims of this study were to identify candidate anti-aging herbal formulae(CAHF) from Dongeuibogam. Methods : We analyzed the terms describing effect of 3,901 herbal formulae on Dongeuibogam and selected the terms describing the anti-aging effect of herbal formulae(TAEHF). Finally, we generated a list of CAHFs based on TAEHFs. Results & Conclusions : 1. We finally selected 162 TAEHFs on Dongeuibogam. 2. We finally selected 138 CAHFs on Dongeuibogam(15CAHFs for external use, 123CAHFs for internal use). 3. TAEHFs are classified into 9 types. 4. CAHFs are classified into 9 types.

• ETRI Journal
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• v.36 no.4
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• pp.609-616
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• 2014

Even though many computational methods (recursive formulae) for blocking probabilities in finite-capacity M/D/1 queues have already been produced, these are forms of transforms or are limited to single-node queues. Using a distinctly different approach from the usual queueing theory, this study introduces explicit (transform-free) formulae for a blocking probability, a stationary probability, and mean sojourn time under either production or communication blocking policy. Additionally, the smallest buffer capacity subject to a given blocking probability can be determined numerically from these formulae. With proper selection of the overall offered load ${\rho}$, the approach described herein can be applicable to more general queues from a computational point of view if the explicit expressions of random vector $D_n$ are available.

• Journal of the Korea Society for Simulation
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• v.12 no.1
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• pp.11-19
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• 2003

Dubins showed that any shortest path of a car-like robot consists of exactly three path segment which are either arcs of circles of radius r(denoted C), or straight line segments(denoted S). Possible six types classified into two families, i.e. CSC and CCC. CSC includes 2 types(LRL and RLR) and CSC includes 4 types(LSL, RSR, LSR, RSL). This paper proposes new formulae for CSC family to find the shortest smooth path between the initial and final configurations of a car-like robot. The formulae is used for finding connection points explicitly between C\longrightarrowS and S\longrightarrowC which are necessary for real applications. The formulae have simple forms mainly because they are transformed into origin of their original coordinates of initial and target configuration, and derived from a standard forms which are a representative configuration of LSL and LSR type respectively. The proposed formulae, which are derived from the standard forms, are simple and new method.

• Natural Product Sciences
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• v.8 no.4
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• pp.173-176
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• 2002

The possibility of Chungpesagantang, Sunghyangjunggisan and Yangkyuksanwhatang, which have been recommended for stroke patients with constipation in traditional Korean clinics, was evaluated as a novel antithrombotic agent. Chungpesagantang potently inhibited ADP- and collagen-induced rat platelet aggregation in vitro, but Sunghyangjunggisan and Yangkyuksanwhatang did not inhibit it. However, all tested herbal formulae inhibited in vivo ADP- and collagen-induced rat platelet aggregation and extended the bleeding time of mice tails. All these herbal formulae did not affect certain plasma clotting times such as APTT, PT and TT. Among these herbal formulae, Chungpesagantang showed significant protection against death due to pulmonary thrombosis in mice. Based on these findings, these herbal formulae should prevent thrombosis and cardiovascular diseases such as myocardial infraction stroke, and arteriosclerosis.

• Honam Mathematical Journal
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• v.35 no.3
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• pp.507-513
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• 2013

In this paper, we compute transformation formulae for generalized non-holomorphic Eisenstein series.

• Herbal Formula Science
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• v.26 no.2
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• pp.147-170
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• 2018

Objectivs : This report describes the studies as follows through the research of 163prescribtions in low-chapter from Bangyakhappyun. Methods : Analysis the 163prescribtions of basic prescribtions, therapeutic area, symptoms and pathology. Result : Many prescriptions are contained in the diseases areas such as defecate diseases, women diseases, internal diseases, exogenous febrile diseases. And prescriptions in the low-chapter are used in the areas such as eye, aggregation, mouth and tongue, teeth, hand, back, neck, emergency. Eighty-five basic prescriptions are analyzed from the low-chapter and the ratio of nineteen prescriptions containing Ijintang, Pyeongwisan, Oryungsan, Samultang, Sunggitang, Jichultang are over 60%. The efficacy classifications containing basic prescriptions frequently used are researched in the following order: heat-clearing and fire-purging formulae, digestant formulae, phlegm-dispelling formulae, qi-regulating formulae and blood-activating formulae. And tonifying and replenishing formulae are rarely used. Most of the prescriptions in the low-chapter are used for the excess syndrome and few of them are used for the deficiency syndrome. And six excesses, food damage, phlegm are the major causes of excess syndrome. Conclusions : As s result of study on analysis all prescriptions in low-chapter from Bangyakhappyun. We can understand more about basic prescriptions, symptoms of prescriptions and pathology.

• Journal of Korea Water Resources Association
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• v.48 no.6
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• pp.479-489
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• 2015

The objective of this study is to develop the equations for concentration time and storage coefficient considering regional trend in urban stream watershed for reliable hydrological analysis. The 13 basins located in Jungrang, Tan, Anyang, and Hongje stream are selected for the data collection and formula development in this study. The stepwise multiple-regression analysis is used for the development considering watershed, urban, and precipitation characteristic indices. The developed formulae are compared with the domestic and foreign empirical formulae and evaluated the accuracy in urban stream area. It shows the computed value from the equation developed in this study is more accurate than those from other empirical formulae. The error sum, average error and RMSE of computed values from the developed equations in this study are the lowest. The formulae considering the regional trend of urban stream watershed are worth in terms of showing better results than the domestic and foreign empirical formulae. It can be concluded the developed formulae can be useful in urban stream watershed.

• Integrative Medicine Research
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• v.6 no.4
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• pp.395-403
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• 2017

Background: Gamisoyosan (GSS) is an herbal formula which has been used to treat women's diseases for several hundred years in Korea. GSS is one of the three most common prescriptions among women and is used to treat menopausal symptoms. Fatty liver disease is also common in postmenopausal women and can precede more severe diseases, such as steatohepatitis. The present study compared the effects of GSS on fatty liver using three different formulae, Dongui-Bogam (KIOM A), Korean Pharmacopeia (KIOM B) and Korean National Health Insurance (KIOM C). Methods: In oleic acid-induced HepG2 fatty liver cells, cellular lipid accumulation, triglycerides and total cholesterol were measured after treatment with three GSS formulae and simvastatin as a positive control. To investigate the phytoestrogen activity of GSS, MCF-7 cells were treated with GSS, and hormone levels were quantified. Also, qualitative analysis was performed with UPLC. Results: All types of GSS decreased cellular lipid accumulation. KIOM A was slightly less effective than the other two GSS formulae. KIOM B and KIOM C decreased cellular triglycerides more effective than simvastatin, but KIOM A did not affect cellular triglycerides. Cellular total cholesterol was decreased by all GSS and simvastatin. GSS showed phytoestrogen activity in MCF-7 cells. From the UPLC analysis data, geniposide, paeoniflorin and glycyrrhizin were detected form three GSS formulae. Conclusion: These results suggest that all GSS formulae have a beneficial effect on fatty liver disease during menopause and that differences of formula have no effect on the efficacy of the prescription.

• Korean Journal of Acupuncture
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• v.39 no.2
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• pp.34-42
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• 2022

Objectives : Parkinson's disease (PD) is a neurodegenerative disease caused by dopaminergic neuronal death in the substantia nigra pars compacta. PD is known to be linked with mitochondrial dysfunction and increased oxidative stress. In this study, anti-cytotoxic and anti-oxidative effect of 12 herbal formulae were compared. Methods : According to experts' advice, 12 types of herbal formulae (Gamisoyosan, Galgeuntang, Galgeunhaegitang, Banhabaekchoolcheonmatang, Bojungikgitang, Boheotang, Sihogyejitang, Sihosogantang, Sihocheonggantang, Ojeoksan, Cheongsanggyeontongtang and Palmultang) were selected from 56 types of herbal formulae covered by the National Health Insurance Service in Korea. To detect anti-oxidative effect, 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay was performed, and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay was performed to detect anti-cytotoxic effect of 12 herbal formulae using SH-SY5Y human neuroblastoma cells. Results : In DPPH assay, anti-oxidant activity was increased in a dose-dependent manner and half maximal inhibitory concentration was highest in the order of Galgeuntang, Gamisoyosan, Galgeunhaegitang, Ojeoksan, Palmultang, Sihogyejitang, Sihosogantang, Cheongsanggyeontongtang, Sihocheonggantang, Bojungikgitang, Boheotang and Banhabaekchoolcheonmatang. In MTT assay, concentration of 80% cell survival was highest in the order of Sihosogantang, Cheongsanggyeontongtang, Sihocheonggantang, Sihogyejitang, Bojungikgitang, Galgeuntang, Ojeoksan, Boheotang, Palmultang, Galgeunhaegitang, Banhabaekchoolcheonmatang and Gamisoyosan. Formulae with more than 50% DPPH radical scavenging activity at concentrations for 80% cell survival were Sihosogantang, Cheongsanggyeontongtang, Sihogyejitang, Galgeuntang and Sihocheonggantang. Conclusions : Sihosogantang, Cheongsanggyeontongtang, Sihogyejitang, Galgeuntang and Sihocheonggantang extracts can be candidate medicines for PD, but the effect should be validated in PD models.

• Proceedings of the KIPE Conference
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• 2003.07b
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• pp.994-997
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• 2003

Simple tuning formulae are derived to design a Pl controller to meet the gain and phase margin specifications. These formulae are suitable for the auto-tuning of a process where the robustness should be guaranteed. The auto-tuned PI controller is examined for the speed regulation of a PM synchronous motor.