• Title/Summary/Keyword: Form Function

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7-Oxostaurosporine Selectively Inhibits the Mycelial Form of Candida albicans

  • Hwang, Eui-Il;Yun, Bong-Sik;Lee, Sang-Han;Kim, Soo-Kie;Lim, Se-Jin;Kim, Sung-Uk
    • Journal of Microbiology and Biotechnology
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    • v.14 no.5
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    • pp.1067-1070
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    • 2004
  • In the course of screening for specific inhibitors against the mycelial form of Candida albicans from natural resources, we have isolated and identified A6792-1 from Streptomyces sp. A6792 by using several chromatographies. By spectral analyses, this compound was determined as 7-oxostaurosporine, having a structure of staurosporine aglycon noiety. 7-Oxostaurosporine exhibited a selective growth inhibitory activity against the mycelial form of Candida spp. up to $100\mu\textrm{g}/disc$ in bioassay. It also exhibited a specific antifungal activity against the mycelial form of Candida spp. including C. krusei, C. albicans, C. tropicalis, and C. lusitaniae with MICs ranging from 3.1 to $25\mu\textrm{g}/ml$ 7-Oxostaurosporine demonstrated no in vivo toxicity in SPF ICR mice. Therefore, this compound may have a considerable potential as an antifungal agent based on the preferential inhibition against growth of the mycelial form of Candida spp., dimorphic fungi.

Analysis of Coplanar Waveguide Discontinuities Using Accurate Closed-Form Green's function (정확한 Closed-Form 그린함수를 이용한 코플래너 도파로 불연속 해석)

  • Kang, Yeon-Duk;Song, Sung-Chan;Lee, Taek-Kyung
    • Journal of Advanced Navigation Technology
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    • v.7 no.2
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    • pp.180-190
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    • 2003
  • By using accurate closed-form Green's functions obtained from real-axis integration method, the full-wave analysis of CPW discontinuities are performed in space domain. In solving MPIE(Mixed Potential Integral Equation), Galerkin's scheme is employed with the linear basis functions on the triangular elements in air-dielectric boundary. In the singular integral arising when the observation point and source point coincides, the surface integral is transformed into the line integral and the integral is evaluated by regular integration. By using the Green's function from the real-axis integration method, the discontinuities are characterized accurately.

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A local point interpolation method for stress analysis of two-dimensional solids

  • Liu, G.R.;Gu, Y.T.
    • Structural Engineering and Mechanics
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    • v.11 no.2
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    • pp.221-236
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    • 2001
  • A local point interpolation method (LPIM) is presented for the stress analysis of two-dimensional solids. A local weak form is developed using the weighted residual method locally in two-dimensional solids. The polynomial interpolation, which is based only on a group of arbitrarily distributed nodes, is used to obtain shape functions. The LPIM equations are derived, based on the local weak form and point interpolation. Since the shape functions possess the Kronecker delta function property, the essential boundary condition can be implemented with ease as in the conventional finite element method (FEM). The presented LPIM method is a truly meshless method, as it does not need any element or mesh for both field interpolation and background integration. The implementation procedure is as simple as strong form formulation methods. The LPIM has been coded in FORTRAN. The validity and efficiency of the present LPIM formulation are demonstrated through example problems. It is found that the present LPIM is very easy to implement, and very robust for obtaining displacements and stresses of desired accuracy in solids.

AN OPTIMAL INEQUALITY FOR WARPED PRODUCT LIGHTLIKE SUBMANIFOLDS

  • Kumar, Sangeet;Pruthi, Megha
    • Honam Mathematical Journal
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    • v.43 no.2
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    • pp.289-304
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    • 2021
  • In this paper, we establish several geometric characterizations focusing on the relationship between the squared norm of the second fundamental form and the warping function of SCR-lightlike warped product submanifolds in an indefinite Kaehler manifold. In particular, we find an estimate for the squared norm of the second fundamental form h in terms of the Hessian of the warping function λ for SCR-lightlike warped product submanifolds of an indefinite complex space form. Consequently, we derive an optimal inequality, namely $${\parallel}h{\parallel}^2{\geq}2q\{{\Delta}(ln{\lambda})+{\parallel}{\nabla}(ln{\lambda}){\parallel}^2+\frac{c}{2}p\}$$, for SCR-lightlike warped product submanifolds in an indefinite complex space form. We also provide one non-trivial example for this class of warped products in an indefinite Kaehler manifold.

A Geometric Derivation of the Craig Representation for the Two-Dimensional Gaussian Q-Function (이변량 가우시안 Q-함수의 Craig 표현에 대한 기하학적인 유도)

  • Park, Seung-Keun;Lee, Il-Kyoo
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.36 no.4A
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    • pp.325-328
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    • 2011
  • In this paper, we present a new and simple derivation of the Craig representation for the two-dimensional (2-D) Gaussian Q-function in the viewpoint of geometry. The geometric derivation also leads to an alternative Craig form for the 2-D Gaussian Q-function. The derived Craig form is newly obtained from the geometry of two wedge-shaped regions generated by the rotation of Cartesian coordinates over two correlated Gaussian noises. The presented Craig form can play a important role in computing the probability represented by the 2-D Gaussian Q-function.

MOCK THETA FUNCTIONS OF ORDER 2 AND THEIR SHADOW COMPUTATIONS

  • Kang, Soon-Yi;Swisher, Holly
    • Bulletin of the Korean Mathematical Society
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    • v.54 no.6
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    • pp.2155-2163
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    • 2017
  • Zwegers showed that a mock theta function can be completed to form essentially a real analytic modular form of weight 1/2 by adding a period integral of a certain weight 3/2 unary theta series. This theta series is related to the holomorphic modular form called the shadow of the mock theta function. In this paper, we discuss the computation of shadows of the second order mock theta functions and show that they share the same shadow with a mock theta function which appears in the Mathieu moonshine phenomenon.

ESTIMATION OF NON-INTEGRAL AND INTEGRAL QUADRATIC FUNCTIONS IN LINEAR STOCHASTIC DIFFERENTIAL SYSTEMS

  • Song, IL Young;Shin, Vladimir;Choi, Won
    • Korean Journal of Mathematics
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    • v.25 no.1
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    • pp.45-60
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    • 2017
  • This paper focuses on estimation of an non-integral quadratic function (NIQF) and integral quadratic function (IQF) of a random signal in dynamic system described by a linear stochastic differential equation. The quadratic form of an unobservable signal indicates useful information of a signal for control. The optimal (in mean square sense) and suboptimal estimates of NIQF and IQF represent a function of the Kalman estimate and its error covariance. The proposed estimation algorithms have a closed-form estimation procedure. The obtained estimates are studied in detail, including derivation of the exact formulas and differential equations for mean square errors. The results we demonstrate on practical example of a power of signal, and comparison analysis between optimal and suboptimal estimators is presented.

Radial basis collocation method for dynamic analysis of axially moving beams

  • Wang, Lihua;Chen, Jiun-Shyan;Hu, Hsin-Yun
    • Interaction and multiscale mechanics
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    • v.2 no.4
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    • pp.333-352
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    • 2009
  • We introduce a radial basis collocation method to solve axially moving beam problems which involve $2^{nd}$ order differentiation in time and $4^{th}$ order differentiation in space. The discrete equation is constructed based on the strong form of the governing equation. The employment of multiquadrics radial basis function allows approximation of higher order derivatives in the strong form. Unlike the other approximation functions used in the meshfree methods, such as the moving least-squares approximation, $4^{th}$ order derivative of multiquadrics radial basis function is straightforward. We also show that the standard weighted boundary collocation approach for imposition of boundary conditions in static problems yields significant errors in the transient problems. This inaccuracy in dynamic problems can be corrected by a statically condensed semi-discrete equation resulting from an exact imposition of boundary conditions. The effectiveness of this approach is examined in the numerical examples.

CLASSIFICATION OF SINGULAR SOLUTIONS FOR THE POISSON PROBLEM WITH VARIOUS BOUNDARY CONDITIONS

  • Kim, Seok-Chan;Woo, Gyung-Soo;Kong, Soo-Ryoun
    • Honam Mathematical Journal
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    • v.31 no.4
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    • pp.579-590
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    • 2009
  • The precise form of singular functions, singular function representation and the extraction form for the stress intensity factor play an important role in the singular function methods to deal with the domain singularities for the Poisson problems with most common boundary conditions, e.q. Dirichlet or Mixed boundary condition [2, 4]. In this paper we give an elementary step to get the singular functions of the solution for Poisson problem with Neumann boundary condition or Robin boundary condition. We also give singular function representation and the extraction form for the stress intensity with a result showing the number of singular functions depending on the boundary conditions.

A Study on the Formal Composition in internal space of Louis I. Kahn's Architecture - Focus on the Formal Composition of skylight - (루이스 칸 건축의 실내공간에 나타나는 형태구성에 관한 연구 - 천창의 형태구성을 중심으로 -)

  • Roh, Su-Jin;Kim, Kyoung-Yon;Kim, Hyung-Woo
    • Proceedings of the Korean Institute of Interior Design Conference
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    • 2007.05a
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    • pp.222-226
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    • 2007
  • Buildings form interior space when part of an external environment is limited by a physical surface. And, the interior space forms an appearance of building when space-defining elements, such as floor, wall, and roof. An appearance or a form of building has a lot of meanings depending on the physical and psychological conditions, as well as symbolism. Especially, the prevailing meaning of form in the modern age was, "Form follows function," was quite different from the meaning of form in the architectural era of Louis I. Kahn, who asserted "Form always supercedes function," when functional modernism was still existed even after some 50 years later. Existing studies on Louis I. Kahn usually analyzed his architectural terminology and philosophical concepts of Centrality, Light, Order, Form, and Design; or they were focused on an overall plane and the principle of composition. The purposes of this study are: (1) to investigate how the formal composition characteristics of building are expressed on skylights; and (2) to demonstrate that the formal composition characteristics of skylights plays an important role in constructing a whole structure of building in relation with other architectural elements.

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