• The Journal of Internal Korean Medicine
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• v.40 no.6
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• pp.1112-1121
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• 2019

Objectives: FDY003 is a raw material for medicine consisting of a natural product that is expected to have the advantages of low side effects and high efficacy. In this study, we predict the efficacy and the standardization of the drug by method validation of anticipated index compounds and the measurement of antioxidant activity. Methods: FDY003 is prepared by extracting and purifying 70% of ethyl alcohol (EtOH). The method validation of cordycepin and chlorogenic acid was determined by high-performance liquid chromatography-photo diode array (HPLC-PDA) and the content of FDY003 was calculated. In order to monitor the biological activity of FDY003, antioxidant activity was measured by 1,1-diphenyl-2-picrylhydrazyl (DPPH), 2,2-azino bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), and ferric-reducing antioxidant power (FRAP). The equivalent values of antioxidants such as trolox, ascorbic acid, gallic acid, and caffeic acid were measured by ABTS and FRAP. Results: Chlorogenic acid and cordycepin were both found suitable for method validation in HPLC and FDY003 containing 9.92±0.50 and 17.97±0.27 ㎍/g, respectively. In DPPH, the electron donating ability (EDA) value of FDY003 was increased in a concentration dependent manner. FDY003 confirmed antioxidant activity by ABTS and FRAP. Conclusions: FDY003 contains certain components including cordycepin and chlorogenic acid and has antioxidant ability by various mechanisms. Therefore, it is expected that FDY003 is capable of various physiological activities including anti-cancer activity.

• Journal of the Korean Wood Science and Technology
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• v.48 no.6
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• pp.907-916
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• 2020

This research was conducted to investigate the linear expansion and resistance properties of a composite board (com-ply). This board was made of medium-density fiberboard (MDF) laminated using avocado (Persea americana), mahogany (Swietenia mahogani), and pine (Pinus merkusii) veneers. These three types of veneers were laminated on both surfaces of the MDF using adhesives, namely, epoxy and isocyanate. Glue (250 g·m^-2) was spread on the surface, followed by cold press for 3 h with an applied pressure of 15 kg·cm^-2. The research result revealed that com-ply exhibited an increased dimensional stability compared with MDF, indicated by reduction in water absorption, thickness swelling, and linear expansion. The com-ply made of the pine veneer and isocyanate adhesive exhibited high density, water absorption, thickness swelling, and screw withdrawal load. The com-ply that exhibited the strongest resistance to drywood termite attacks was the one made of the mahogany veneer and isocyanate adhesive. Moreover, the com-ply that exhibited the biggest weight loss (3.6 %) was made of the pine veneer and epoxy adhesive. The results of this research may facilitate in manufacturing com-ply using the selected veneer and adhesive without the application of hot press.

• Journal of the Korean Wood Science and Technology
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• v.48 no.1
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• pp.95-106
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• 2020

The purpose of this study was to determine the effects of coniferous essential oils (EOs) blended films on insect repellence and crop productivity. Low-density polyethylene (LDPE) film is widely used, especially in agriculture and for food packaging. Ethylene vinyl acetate was blended with LDPE to reduce volatilization of EOs. An EO from Japanese cypress (Chamaecyparis obtusa) was incorporated into the blend film to conduct field research on antimicrobial and insect repellent properties. Among the various concentrations of EO, the highest concentration (2.5%) showed the highest efficiency in terms of pesticidal activity. The ability to inhibit microbial growth can be explained by the lipophilic properties of the EO component, and many studies have already demonstrated this. Agricultural films containing all types of EO have been tested on various crops such as chili, cucumber, Korean melon and have been able to verify their effectiveness in avoiding pests and increasing yields. From these results, it was found that it is reasonable to use a modified film such as a composite film containing an EO for agriculture. Thus, the modified film containing EO has undoubtedly shown impressive potential for reducing the use of pesticides in a variety of ways, not only for agricultural mulching film but also for food and agricultural product packaging. This product is an environmentally friendly chemical and is safe for agricultural and industrial and food packaging applications, among others. In particular, the use of agricultural films significantly reduces the use of pesticides, suggesting that farmers can increase their incomes by reducing working hours and costs, and increasing production.

• Journal of The Korean Society of Agricultural Engineers
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• v.61 no.2
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• pp.75-83
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• 2019

Using geographical indication, a type of source identification, can effectively promote local specialty agricultural products of superior quality, by identifying the specific geographic location or origin of the produce. Agricultural products can be registered using the geographical indication by describing the product's relation to its geographical origin including the reputation and quality. However, this indication has no objective standards to qualify goods as agricultural specialty products. The purpose of this study is to suggest basic criteria to define the characteristics and criteria of agricultural specialties based on a quantitative evaluation method. To propose this basic standard, we used the proportion of arable land to denote the major production areas and the location quotient (LQ) index to grasp the extent of the specialty of a product. The results show that the average LQ values of registered agricultural products, particularly apples, pears, and garlic, are 3.26, 8.01, and 2.82, respectively. This indicates that they are more specialized than produce from other areas that have not registered for a geographical indication. Low LQ values were found in some areas with registered rice geographical indications, which are also more focused on their historical reputation as the main rice producing areas. Considering the agricultural specialty of products, the recommendation is that the producing proportion should be over 1% of the national scale and over 10% of the province scale, and the LQ value should be over 2.0. This recommendation is not a requirement, but the criteria can prove to be useful in identifying a higher range of specialized agricultural products.

• Journal of the Korea Society of Computer and Information
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• v.27 no.5
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• pp.29-36
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• 2022

In this paper, we propose an efficient agricultural products price prediction model based on dataset which provided in DACON. This model is XGBoost and CatBoost, and as an algorithm of the Gradient Boosting series, the average accuracy and execution time are superior to the existing Logistic Regression and Random Forest. Based on these advantages, we design a machine learning model that predicts prices 1 week, 2 weeks, and 4 weeks from the previous prices of agricultural products. The XGBoost model can derive the best performance by adjusting hyperparameters using the XGBoost Regressor library, which is a regression model. The implemented model is verified using the API provided by DACON, and performance evaluation is performed for each model. Because XGBoost conducts its own overfitting regulation, it derives excellent performance despite a small dataset, but it was found that the performance was lower than LGBM in terms of temporal performance such as learning time and prediction time.

• Journal of Convergence for Information Technology
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• v.12 no.3
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• pp.1-10
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• 2022

Vegetables such as cabbage are greatly affected by natural disasters, so price fluctuations increase due to disasters such as heavy rain and disease, which affects the farm economy. Various efforts have been made to predict the price of agricultural products to solve this problem, but it is difficult to predict extreme price prediction fluctuations. In this study, cabbage prices were analyzed using the ensemble Voting technique, a method of determining the final prediction results through various classifiers by combining a single classifier. In addition, the results were compared with LSTM, a time series analysis method, and XGBoost and RandomForest, a boosting technique. Daily data was used for price data, and weather information and price index that affect cabbage prices were used. As a result of the study, the RMSE value showing the difference between the actual value and the predicted value is about 236. It is expected that this study can be used to select other time series analysis research models such as predicting agricultural product prices

• Journal of the Korean Wood Science and Technology
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• v.52 no.1
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• pp.13-30
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• 2024

Swietenia mahagoni is one of the commercial timbers in Indonesia. Mahogany heartwood is an important characteristic as it relates to the natural durability and aesthetics of the wood. Lipophilic extractives are known to be involved in the heartwood formation process. Therefore, this study aims to determine the lipophilic compounds associated with heartwood formation. The n-hexane extract from sapwood and heartwood samples (1 to 5 years) was analyzed by gas chromatography-mass spectrometry. The results showed that the content of n-hexane extract ranged from 0.76% to 2.45% based on dry wood. The main group of compounds identified in the lipophilic fraction consisted of sterols (β-sitosterol, stigmasterol, campasterol, and cyclolaudenol), fatty acids (palmitic, oleic, linoleic, and stearic acid), and hydrocarbons (pentadecane, 1-octadecane, hexadecane, cyclotetracosane, cycloeicosane, and cyclooctacosane) after heartwood formation. In addition, the hydrocarbon fraction was the largest, followed by sterols, fatty acids, and 1-heneicosanol. In the radial variation, the distribution of fatty acids was greater in the sapwood than in the heartwood (4-year-old). However, the reverse pattern was found at the age of 5 years. The lipophilic fraction was generally more abundant in the heartwood compared to the sapwood, especially at 5 years of age, with much higher levels than when the heartwood was forming (4 years). These findings show that when the heartwood formation begins, the lipid composition was not fully metabolized at the beginning of heartwood formation compared to 5-year-old trees.

• Bulletin of the Korean Chemical Society
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• v.28 no.1
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• pp.49-52
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• 2007

Prodigiosin (1) is the parent member of a class of polypyrrole natural products that exhibit promising anticancer activities. They can facilitate copper-promoted oxidative DNA damage by binding to copper ions, and this activity is thought to represent their mechanism of cytotoxicity in the dark. They also possess photoinduced cytotoxicity, although 1 is too toxic in the dark to be used effectively for the treatment of cancer by photodynamic therapies. To circumvent dark toxicity by prodigiosins, the semi-synthetic analogue 2, in which the N-pyrrolic atoms of 1 are methylated to block copper coordination, and the synthetic phenyl analogues 3 and 4, which lack the copper-coordinating A-pyrrole ring of 1, were tested for their ability to inhibit colony formation of HL-60 cancer cells in the absence and presence of visible light (λ > 495 nm). Our results show that 2-4 lack cytotoxicity in the dark, but are able to inhibit colony formation of HL-60 cells following irradiation for 30 min. The synthetic derivative 4 exhibits photo-induced cytotoxicity similar to that of the natural product 1, demonstrating the potential use of prodigiosin-based compounds for treatment of cancers following irradiation with visible light.

• Journal of the Korean Wood Science and Technology
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• v.45 no.3
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• pp.268-277
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• 2017

In this study, lignocellulose nanofibrils (LCNFs) were prepared from Pussy willow wood powder by disk-milling after pretreatment using the cosolvent of 1-ethyl-3-methylimidazolium acetate ([EMIM]Ac) and N,N-dimethylformamide (DMF) with different mixing ratios for different time. All pretreated samples showed native cellulose I polymorph and cellulose crystallinity was lowest when cosolvent of DMF with 30% [EMIM]Ac was used. Average crystallite size of raw material and the pretreated product by MDF and its cosolvent with 10% [EMIM]Ac was found to be about 3.2 nm and decreased with increasing pretreatment time at the DMF cosolvent with 30% [EMIM]Ac. Defibrillation efficiency was improved by loosening wood cell wall structure by the pretreatment using co-solvent system of [EMIM]Ac and DMF.

• Journal of Korean Society of Forest Science
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• v.98 no.3
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• pp.284-289
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• 2009

This study estimated the fiberboard demand using VAR and econometric model, and compared the prediction accuracy of the two models. And the variance decomposition and impulse response were analyzed using VAR model, and predicted the fiberboard demand. The VAR model was specified with lagged dependent variable, lagged own price, lagged construction product, dummy. The econometric model was specified with own price, substitute price, construction product, dummy. The dummy variable reflected the abrupt decrease in fiberboard demand in the late 1990's. The results showed that the fiberboard demand prediction can be performed more accurately by VAR model than by econometric model. In the VAR model of fiberboard demand, after twelve months, the construction product change accounts for about fifty percent of variation in the demand, and the own price change accounts for about thirty percent of variation in the demand. On the other hand, the impact of a shock to the construction product is significant for about twelve months on the demand of fiberboard, and the impact of a shock to the own price is significant for about six months on the demand of fiberboard.