• 제목/요약/키워드: Folk medicine

검색결과 564건 처리시간 0.03초

일차 배양한 간세포에서의 권백의 간보호효과의 Screening Test (Screening Test of Selaginella tarmariscina for Liver Protective Effects in Primary Cultured Hepatocytes)

  • 윤수홍;이주영;하헌
    • Environmental Analysis Health and Toxicology
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    • 제11권3_4호
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    • pp.65-68
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    • 1996
  • Selaginellae Herba has been used as folk medicine for antineoplastics, coagulants, antidotes and invigorants. To find an in vitro screening method for liver protective effect of Selaginellae Herba in benzo(a)pyrene intoxicated injury were examined in primary cultured rat hepatocytes. Using MTT assay, herba concentration showed dose dependently viability. The lowest concentration of benzo(a)pyrene giving cytotoxicity revealed around 50gM. The hepatoprotective effect of Selaginellae Herba in both water and chloroform extracts was also increased dose dependently.

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Three New Diarylheptanoids from the Roots of Juglans mandshurica

  • Li , Gao;Xu, Ming-Lu;Kim, Jae-Hyon;Seo, Chang-Seob;Kim, Hyo-Jin;Lee, Chong-Soon;Hee, Woo-Mi;Son, Jong-Keun
    • 대한약학회:학술대회논문집
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    • 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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    • pp.370.4-371
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    • 2002
  • The roots of Juglans mandshurica Maximowicz (Juglandaceae) have been used as a folk medicine for treatment of cancer in Korea. Several naphthoquinones and naphthalenyl glucosides from Juglans species have been reported (1-7). In the course of isolating cytotoxic compounds from the roots of this plant. we have isolated six naphthalene glycosides. four tetralone, one naphthalene carboxylic acid glucoside and nine diarylheptanoids (8-13). (omitted)

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Pharmacological actions of H2O and MeOH extract of Opuntia ficus-indica Semen

  • Suh, My-Hyun;Lee, Ji-Yun;Jang, Yong-Un;Sim, Sang-Soo;Kim, Chang-Jong
    • 대한약학회:학술대회논문집
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    • 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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    • pp.299.3-300
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    • 2002
  • Both of Semen (OF-Se) or stem (OF-Sf) of Opuntia ficus-indica Semen have been used as a healthful food or folk medicine in korea for the treatment of asthma. diabetes mellitus. aging, osteoporosis, rheumatic arthritis. constipation, cancer. gastric ulcer. constipation. toxic state, edema, etc, There are many reports that OF have the anti-gastric damage, wound healing, diabetes mellitus, monoamine oxidase B inhibitor etc. (omitted)

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Comparison of CE and HPLC as analytical methods of (-)-yatein enantiomer from Cupressaceae plants

  • Lim, Hwan-Mee;Kim, Young-Ho;Ahn, Byung-Zun;Kim, Kyeong-Ho;Kang, Jong-Seong
    • 대한약학회:학술대회논문집
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    • 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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    • pp.404.3-405
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    • 2002
  • Cupressaceae plants are used in traditional folk medicine. whose extracts have been found to possess some bioactivities. (-)-Yatein is a lignan of the dibenzyl-butyrolactone type. that has been isolated from some Cupressaceae plants. It was reported that (-)-yatein. isolated from plants. showed different activities from the synthetic yatein [3]. Hence. the enantiosetective determination of yatein from synthetic materials and natural products would be necessary. (omitted)

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오매(Mume Fructus) 추출물의 혈행개선 효과 (The Effects of Mume Fructus Extracts on Blood Flow Improvement)

  • 박승희;박금주;김재기
    • 약학회지
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    • 제53권5호
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    • pp.298-302
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    • 2009
  • Mume Fructus extract is used in folk medicine in Eastern Asian countries including Korea. However, its therapeutic effect on thrombosis is not known. Mume Fructus methanol extract (ME) dose-dependently inhibited ADP-induced platelet aggregation and also exhibited about 130% fibrinolytic activity compared to the natto. Oral administration of ME to mice significantly extended tail-bleeding time. ME prolonged both aPTT and PT in human citrated plasma also. These results suggest that the methanol extract from Mume Fructus have antithrombosis activity.

Hydrocotyle japonica의 약효성분에 관한 연구(I) (Studies on the Pharmaco-Constituents of Hydrocotyle japonica (I))

  • 조의환;김일혁
    • 약학회지
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    • 제32권4호
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    • pp.281-286
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    • 1988
  • For the investigation of medicinal resources in Hydrocotyle species, the studies were conducted to evaluate the pharmaco-constituents in Hydrocotyle japonica MAKINO (Umbelliferae), which is used as folk medicine in Korea. From the methyl alcohol extract of the whole plant, $isorhamnetin-3-O-{\beta}-D-galactoside$ ($C_{22}H_{22}O_{12}{\cdot}1/3H_2O$, bright yellow needle crystal, mp $247{\sim}248^{\circ}C$, $[{\alpha}]_D^{28}^{\circ}=-52.27^{\circ}$ in pyridine), one of three flavonol substances in extrat, was isolated and identified by physicochemical properties and spectroscopic evidences (UV, IR, NMR and MS etc.,) in comparison with authentic sample. This flavonoid was appeared from Hydrocotyle japonica MAKINO through phytochemical approaches at the outset.

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Pseudomonas aeruginosa ATCC 27853에 대한 약용식물 추출물들의 활성 (Activity of Nature Plants Extracts against Pseudomonas aeruginosa ATCC 27853)

  • 음진성
    • 한국정보통신학회논문지
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    • 제16권8호
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    • pp.1799-1804
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    • 2012
  • Pseudomonas aeruginosa에 대한 항균물질을 찾기 위하여 한의학에서 전통적으로 사용되어 오던 34종류 약용식물로부터 에탄올 추출물들을 분리하여 항균활성을 조사하였다. Gardenia jasminoides, Arctium lappa, Citrus unshiu 및 Phellodendron amurense 등의 에탄올 추출물들이 P. aeruginosa ATCC 27853에 대해서 항균활성을 나타냈다. 이들 중 Gardenia jasminoides의 에탄올 추출물은 P. aeruginosa에 대해 강한 항균활성을 나타냈다. 앞으로 이들 약용식물들의 추출물들이 P. aeruginosa에 대한 천연항균물질로서 사용될 수 있을 것으로 기대된다.

Cucurbitacin I, a Natural Cell-permeable Triterpenoid, Suppresses Colitis-associated Colon Carcinogenesis in Mice

  • Kim, Hyeon Jin;Kim, Jin-Kyung
    • 대한의생명과학회지
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    • 제19권3호
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    • pp.224-232
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    • 2013
  • Cucurbitacins are a natural cell-permeable triterpenoid compound isolated from Cucurbitaceae and Cruciferae. Cucurbitacins have been used as folk medicine because of their anti-inflammatory and analgesic effects. In the present study, we investigate the anti-cancer effects of cucurbitacin I on colitis-associated colon carcinogenesis induced by azoxymethane (AOM)/dextran sodium sulfate (DSS) in BALB/c mice. Cucurbitacin I treatment attenuated loss of body weight and decreased the number of colon tumors. Western blot analysis showed that cucurbitacin I treatment significantly inhibited the protein expression of inducible nitric oxide synthase (iNOS), tumor necrosis factor (TNF)-${\alpha}$ and interleukin (IL)-6. These results suggest that cucurbitacin I suppressed inflammatory reaction and tumor development in colitis-associated colon carcinogenesis.

손바닥선인장 열매 및 줄기 추출물의 생리활성(II)-흰쥐의 식이성 고지혈증에 미치는 영향 (Biological Activities of the Extracts from Fruit and Stem of Prickly Pear(Opuntia ficus-indica var. saboten) II.-Effects on Dietary induced Hyperlipidemia)

  • 이정규;이영철;문영인;박희준;한용남;최종원
    • 생약학회지
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    • 제33권3호통권130호
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    • pp.230-237
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    • 2002
  • Prickly pear(Opuntia ficus-indica var saboten Makino, Cactaceae) is widely used as folk medicine for burned wound, edema and indigestion. To confirm the hypolipidemic action of the extract from Cactus stem and fruit in dietary hyperlipidemic rats, variations of the lipid- or cholesterol-related components were investigated. As results these changes were significantly prevented by treatments with Cactus extracts. The effects of the extract of fruit was better than those of stem.

관능검사를 통한 씀바귀의 쓴맛 연구 (A Sensory Evaluation of the Bitter Compounds from Ixeris dentata Nakai)

  • 임숙자
    • 한국식품조리과학회지
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    • 제12권1호
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    • pp.115-121
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    • 1996
  • Ixeris dentata Nakai (Compositae) is a perennial herb and the young shoots when prepared properly are edible as a bitter appetizing vegetable in the early spring. The whole plant has been used as a folk medicine in treating diabetes in Korea. As a part of our studies on bitter substances, we have investigated the bitterness of the plant through a taste-guided fractionation method. Bitter substances were extracted by the solvent fractionation and the bitterness was evaluated by 10 trained panelists consisted with graduate students of Dept. of Foods and Nutrition. It has been revealed that the bitter compounds were distributed throughout the extracting fractions and the higher intensity of the bitterness was seen in the n-BuOH fractions. The bitter compounds were subfractionated by the silica gel column chromatography and the bitterness was evaluated by the trained panelists. The subfractions which were indicated as the bitter compounds will be further studied to isolate the compounds. The H$_2$O fractions were grouped according to the molecular weight through the ultrafiltration and the group with 1,000 < m.w. < 30,000 was evaluated as the most intense bitter subfraction.

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