• Natural Product Sciences
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• 제27권2호
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• pp.61-67
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• 2021

Since ancient times, various herbal medicines have been used in folk medicine to treat a variety of diseases. While the majority of drugs belong to the Kingdom of Plantae, some drugs from the Kingdom of Animalia are listed in various Materia medica of alternative medicines. Animal-derived drugs are mentioned in the Unani system of Medicine (USM) and have been used successfully to treat a variety of diseases. Marjān (Corallium rubrum) is a vital marine drug of animal origin that has been used in USM since ancient times and continues to be used today. It possesses a variety of beneficial pharmacological properties, including tonic effects on the heart, brain, stomach, and eyes, pregnancy protection, expectorant, and hemostyptic properties. It is used to treat hemoptysis, palpitation, bleeding piles, hemiplegia, heart failure, and general weakness. It is also an ingredient in a variety of Unani formulations with pharmacological significance. Unani physicians expanded the uses of Marjan and successfully used it to treat a variety of new diseases. There is a dearth of scientific research on its pharmacological and medicinal properties. The urgent need is to validate the Unani claims about its beneficial cardiac and nervine actions, as well as other significant actions mentioned in the Unani literature.

• 대한간호학회지
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• 제17권2호
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• pp.145-152
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• 1987

The problem addressed by this study was to reveal what people of Korean rural villages think about the cause, treatment and prevention of illness. The purpose was to contribute to the building of a concept of health toward the development of Korean Nursing Theory. Subjects were residents of five districts among four counties in a farming area of Chonbuk province recommended by health workers as appropriate informants. They were interviewed in their homes, using ethnoscientific methods developed in anthropology. The research tool consisted of open questions developed through the literature and preliminary exploratory interviews. Data were analyzed by classifying each concepts of cause, treatment and prevention of illness or illness symptoms collated by frequency and percentage. The causes of illness are conceived as primarily concrete physical and natural, for examples, overeating, lack of energy, changes in the season and extreme temperatures. Compared to others studies, few supernatural causes related to traditional view of illness were identified. Concepts of the treatment of illness included formal treatments used by modern western or oriental physicians and traditional therapists. But folk medicine used by traditional healers or by the family in the home was most prevalent. The concept of illness prevention originated in the concept of the cause of illness, thus primarily physical and natural, for examples, nutritious food, limiting the amount of food, avoiding becoming cold. When the concept of illness of rural Korean is researched from a sociocultural aspect, the traditional views of an evil cause of ill health and treatment by supernatural methods is not found to be prevalent but folk medicine still occupies a large place in treatment which si often a complex mixture from many mysterious sources. The significance of this study lies in the fact that ethnonursing research can contribute basic data toward the development of Korean nursing theories. Modern western medical concepts have not been accepted unconditionally: traditional concepts are alive and dynamic in Korea and must be recognized in Korean nursing.

• 고문화
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• 64호
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• pp.47-74
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• 2004

필자는 민속의약에 대한 연구가 일천한 현실에서 이에 대한 이해를 도울 목적으로 350년의 역사와 전통을 갖는 대구약령시(大邱藥令市)를 중심으로 전통의약과 관련한 유$\cdot$무형 전승문화의 존재양상을 유물과 자료, 지식과 기능, 행위전승 등의 측면으로 나누어 고찰해 보고자 하였다. 대구약령시의 유$\cdot$무형 전승문화는 약령시의 고유기능 수행과 관련하여 오래 전부터 전해져 내려온 유형적 문화요소와 기능$\cdot$지식$\cdot$행위양식$\cdot$규범 등의 무형적 은화요소를 총칭한다. 약령시 전승문화는 약령시 사람들의 생업활동과 관련된 물질전승과 기능 지식전승, 행위전승 등으로 대별된다. 물질전승은 한약재의 관리와 유통, 질병 치료를 포함하여 약령시 유지에 필요했던 각종의 물질적 증거들(material evidences)로서 약령시전시관과 한방 관련업소 등에 전시 및 소장되어 있다. 지식$\cdot$기능전승은 한약재를 정선(세척$\cdot$절단$\cdot$건조$\cdot$선별$\cdot$작근) 하여 저장$\cdot$유통시킴은 물론 약으로 제조하거나 치료하는 등의 관련 지식과 기능을 의미한다. 이는 대부분 업소에 오래 동안 종업원으로 근무하면서 형성되는 전인적 인간관계에 기초한 도제시스템에 의해 전승되어 榮다. 대구약령시에는 유구한 역사와 전통 및 전문 인력의 밀집과 수세대에 걸친 비전(秘傳) 등으로 많은 비방과 탁월한 약재 감별지식이 전승되고 있다. 약령시 행위전승은 약령시의 생활경험 및 문화사적 의의와 가치를 발양하고 계승하기 위해 반복되는 행위의 여러 표상들을 제의적$\cdot$기예적$\cdot$오락적 차원으로 정형화한 것으로서 약령시축제와 약령제가 대표적이다. 이상의 사실처럼, 대구약령시는 민속의약 전통에 대한 맥락적 이해를 가능하게 해주는 중요한 삶의 공간이자 민속의약의 저수지이기도 하다. 따라서 약령시 사람들의 생활경험과 기억을 포함하여 관련 물증들을 시$\cdot$공간적 차원에서 수집$\cdot$분류$\cdot$해석하고 효율적으로 보존$\cdot$계승$\cdot$발전시킬 수 있는 방안을 강구할 필요가 있다.

• 농촌의학ㆍ지역보건
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• 제24권1호
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• pp.103-113
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• 1999

이 연구는 1997년 3월부터 1999년 2월까지 경상북도 소재 일개 군지역에서 피부질환으로 피부과 전문의의 검진을 받은 환자 847명 중 설문조사가 가능하였던 760명의 환자를 대상으로 이들 환자별 성별연령별 분포를 조사하고 치료 경험 여부와, 처음 치료를 시작한 곳과 민간 요법이나 개인적인 치료법 사용여부 및 치료 경험이 있을 경우 그 효과에 대한 만족도를 조사하여 환자들이 피부 질환의 진료 및 치료에 있어 어떤 경로를 밟고 그 일반적인 치료 행태의 경향은 어떠한지를 분석하고자 시행하였으며 다음과 같은 결과를 얻었다. 1. 총 760명의 조사대상자는 남자가 283명으로 37.2%였고 여자가 477명으로 67.3%였다. 총 대상환자 중 20대 환자가 3.3%로 가장 적었고 60대 환자가 21.3%로 가장 많았다. 2. 대상 환자들에게 빈도가 높은 15개 질환은 족부 백선이 34.9%로 가장 많았고 노인성 소양증, 접촉성 피부염, 주부습진, 지루성 피부염, 화폐상 습진, 아토피성 피부염, 체부 백선, 조갑 백선, 심상성 여드름, 전염성 농가진, 박탈성 각질용해층, 만성 두드러기 및 전염성 연속중의 순이었다. 3. 환자들이 피부질환을 위해 최초로 치료받은 곳은 약국이 39.6%로 가장 많았으며, 피부과 전문의가 아닌 개인의원, 피부과 의원 및 종합병원 피부과의 순이었다. 4. 대상환자 760명 중 121명(15.9%)이 민간 요법을 사용한 경험이 있었으며 이 중 가장 많이 사용하는 방법으로서는 환부를 식초에 담그거나 도포하는 방법이었다. 이러한 민간 요법을 시행한 후 환자 본인이 느끼는 자각증상은 변화가 없었다는 경우가 가장 많았고 호전되었다, 악화되었다의 순으로 빈도가 높았다. 결론적으로 농촌지역의 경우 다수의 피부과 환자들이 약국에서 일차진료를 받고 있는 현실이며 피부질환에 대한 인식이 낮음으로 인해 의학적 근거가 없는 다양한 민간요업을 시행하고 있었다. 그러므로 환자들이 잘못된 치료 행태로 인해 경제적, 시간적 손실을 입지 않게 올바른 보건교육이 이루어져야 될것으로 생각된다.

• 약학회지
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• 제44권1호
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• pp.22-28
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• 2000

The extracts of Euphoria longan, Ziryphus jujuba, Thuja orientalis, Polygala tenuifolia, Acorus gramineus, Cyperus rotundus, Poria cocos, Uncaria rhynchophylla, and Albizzia julibrissin, which have been used as sedative drugs in Korean folk medicine, were evaluated for their effects on neurotransmission and antioxidative system in vitro. Among the tested drugs, Acorus gramineus showed most inhibitory activities on monoamine oxidase, xanthine oxidase, aldehyde oxidase, and lipid peroxidation and Uncaria rhynchophylla also inhibited most effectively GABA transaminase and DPPH radical.

• 한방안이비인후피부과학회지
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• 제27권1호
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• pp.37-44
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• 2014

Objective : This study aimed to survey the pattern of the treatment choice for atopic dermatitis. Methods : The questionnaire-based survey was conducted from the parents of 310 patients (median age 9 years, range 2 to 21 year, 158 male and 152 female) with atopic dermatitis. The questionnaire was consisted of 11 questions for the demographic information including treatment choice for atopic dermatitis. Results : The most agonizing factor of atopic dermatitis was pruritus, while the most frequent regions were arms and legs. Conventional therapy (60.3%), folk-remedy (23.9%) and treatment of Korean medicine (15.8%) were the preference of treatment by patients. Over half answers (58.4%) were negative for the current treatments, and the main complains was the absence of radical therapy (26.5%), insufficient information (20.6%), and expensive cost of treatments (19.0%), respectively. Conclusion : This study may provide the important information for the general prospective of parents of patients with atopic dermatitis, which is helpful to develop the Korean medicine-derived therapeutics for atopic dermatitis.

• 동의생리병리학회지
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• 제23권1호
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• pp.158-165
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• 2009

The aim of this study was to clarify the origins of grubs which were used in the experiments, and to determine many other effects that are now written in the classical medical and herbal books. We compared the efficacy of grubs written in the herbal and medical books on the one hand, and studied the origins of grubs used in the experiments, on the other hand. The following results were obtained. There are three kinds of grub species for medicinal uses. Holorichia diomphalia Bates mainly produced in China, Cetoniidae species mainly produced in Korea, and Protaeria brevitarsis in Korean folk remedy are three species. Grubs were used in 25 experiments. Of these experiments, Holotrichia diomphalia were used 12 times, Larve of Protaeria brevitarsis 3 times, and Protaetia orientalis was used once. So, of total 25 experiments, 36%(9 experiments) did not clarify the origins of grubs used in the experiments. Currently, the grubs, which are imported from China and used in Korea, are Holotrichia diomphalia Bates from China. Current experimental study shows that grubs have efficacy for protecting liver. So the use of grubs in folk medicine is believed to be based on the scientific evidence. Efficacy of grubs, though it is not recorded in the medical books, has the effects of anti-cancer(anti-tumor), antioxidant, and anti-diabetes mellitus. The ingredients of Holotrichia are protein, peptide, fat, enzyme, mineral, and other several nutrients. Study on the grubs so far has a tendency to be done with little focus on the differen of origin of grubs. So, from now on, it needs that the origin of grubs be clarified, and the study on the efficacy from each origin be done. Considering the effects that the classical herbal books have recorded, it is necessary that more profound study proceed to prevent and treat diseases on eyes and ears, on the basis of the fact that grub has multiple ingredients to replenish the vital essence.

• 동의생리병리학회지
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• 제21권1호
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• pp.86-92
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• 2007

Hibiscus sabdariffa L., a tropical beverage material, is used commonly as in folk medicine against hypertension, pyrexia, inflammation, liver disorders, and obesity. However, the mechanism by which Hibiscus sabdariffa L. modulates adipogenic differentiation is remained to be elusive. This report was designed to investigate the inhibitory effect of Hibiscus extract on insulin signaling pathway during adipocyte differentiation in 3T3-L1 preadipocytes. 3T3-L1 preadipocytes were differentiated with isobutylmethylxanthine, dexamethasone, and insulin (MDI) and followed by the addition of Hibiscus extract. Treatment with Hibiscus resulted in a decrease of lipid droplet accumulation, which was suppressed by PI-3 kinase inhibitor wortmannin in 3T3-L1 preadipocytes. Also, Hibiscus extract markedly attenuated the mRNA expression of adipogenic transcriptional factor PPAR${\gamma}$ and adipogenic hormon Leptin during adipogenesis. However, it did not affect the expression of adiponectin in 3T3-L1 preadipocytes differentiated with MDI mixture. Furthermore, Adipogenic differentiation by MDI mixture increased the phosphorylation and expression of PI3-Kinase and Akt in 3T3 preadipocytes, which was markedly suppressed by Hibiscus extract treatment. Taken together, our results suggest that Hibiscus extract suppressed the adipogenic differentiation of 3T3 preadipocytes through activation of PI3-Kinase and Akt signaling pathway.

• 대한한의학원전학회지
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• 제26권4호
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• pp.355-366
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• 2013

Based on analysis of the organization and listed formulas of the Sinchanbyeokonbang(新纂辟瘟方), it is clear that it has been published based on the Dong-uibogam(東醫寶鑑). This study was carried out under this premise, with focus on the differences between Sinchanbyeokonbang and the epidemic febrile disease[瘟疫] chapter of the Dong-uibogam. In short, Sinchanbyeokonbang reflected a changed view on the epidemic febrile disease, improving its professionalism by supplementing formulas from previous texts and folk prescriptions. At the same time, it improved clinical practicality rather than medical, academic facts, which shows its objective in improving public health and medicine.

• The Korean Journal of Physiology and Pharmacology
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• 제7권2호
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• pp.91-96
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• 2003

In Korean folk medicine, several herbs, Glycyrrhizae Radix, Persicae Semen, Salviae Radix, Angelicae Gigantis Radix, Zanthoxyli Fructus, Ginseng Radix Alba, Cnidii Rhizoma, and Carthami Flos, are known to enhance blood circulation and have wound healing or anti-inflammatory effects. These pharmacological actions prompted us to investigate whether these herbs might stimulate hair growth. Thus, using a mixture of their extracts called SPELA 707, we investigated their effects and found that SPELA 707 possessed significant hair cycle converting activity from the telogen phase to the anagen phase in C3H mice. Furthermore, we found that SPELA 707 enhanced the hair density in subjects with hair loss and also promoted the conversion of hair into the anagen phase in subjects with androgenetic alopecia. In addition, hair growth promotion effect of SPELA 707 occurred through inhibition of steroid $5{\alpha}$-reductase activity, which is known to block hair growth. Taken together, these results suggest that SPELA 707 has a potential to be used for the treatment of hair loss.