• Journal of the Korean Geotechnical Society
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• v.39 no.11
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• pp.63-70
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• 2023

Underground carbon dioxide (CO₂) storage emerges as a pivotal strategy for mitigating atmospheric CO₂ emissions and addressing global warming concerns. This study investigates techniques to optimize storage efficiency in aquifers, which stand out for their superior capacity compared to other geological layers. The focus is on the application of nonionic and anionic surfactants to enhance CO₂ storage efficiency within confined spaces. A specialized micromodel facilitating fluid flow observation was employed for the evaluation. Experimental results revealed a noteworthy minimum 40% increase in storage efficiency at the lowest injection rate when utilizing nonionic and anionic surfactants, in comparison to pure water injection. Interestingly, no significant variations in storage efficiency were observed based on the ionicity and concentration of the surfactants under investigation. These findings have implications for guiding the selection and concentration determination of surfactants in future underground CO₂ storage endeavors.

• Journal of radiological science and technology
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• v.46 no.5
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• pp.379-394
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• 2023

Targeted Alpha Therapy (TAT) is a new method of cancer treatment that protects normal tissues while selectively killing tumor cells using high cytotoxicity and short range of alpha particles, and target alpha therapy is a highly specific and effective cancer treatment strategy, and its potential has been proven through many clinical and experimental studies. This treatment method accurately delivers alpha particles by selecting specific molecules present in cancer tissue, which has an effective destruction and tumor suppression effect on cancer cells, and one of the main advantages of target alpha treatment is the physical properties of alpha particles. Alpha particles have a very high energy and short effective distance, interacting with target molecules in cancer tissues and having a fatal effect on cancer cells, which is known to cause DNA damage and cell death in cancer cells. TAT has shown positive results in preclinical and clinical studies for various types of cancers, especially those that resist or are unresponsive to existing treatments, but there are several challenges and limitations to overcome for successful clinical transition and application. These include the provision and production of suitable alpha radioisotopes, optimization of target vectors and delivery formulations, understanding and regulation of radiological effects, accurate dosage calculation and toxicity assessment. Future research should focus on developing new or improved isotopes, target vectors, transfer formulations, radiobiological models, combination strategies, imaging techniques, etc. for TAT. In addition, TAT has the potential to improve the quality of life and survival of cancer patients due to the possibility of a new treatment for overcoming cancer, and to this end, prospective research on more carcinomas and more diverse patient groups is needed.

• Journal of Korea Trade
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• v.27 no.5
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• pp.137-152
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• 2023

Purpose - Although many existing studies on the US-China hegemonic conflict and decoupling have been published, most of them are qualitative and use descriptive analysis methods. Papers that quantitatively analyzed decoupling mainly estimate the effect of a tariff increase. However, this paper quantitatively analyzed the ripple effect by focusing on decoupling technology spillover between the United States and China. And, for the first time, it was suggested that the blocking of technology spillover could give a fatal blow to the East Asian economy as well as China. Design/methodology - The United States is pursuing decoupling with China, primarily in goods trade and blocking technology transfer. This paper sets up various scenarios and uses three computational general equilibrium (CGE) models to analyze the overall ripple effects of decoupling. A paper using the three CGE models for decoupling ripple effect analysis has not yet been published. Findings - Decoupling will hit the economies of regions with close economic ties to China more than others. According to simulation results of this study, the Chinese economy may suffer severe damage that is difficult to recover from, and the economies of Asian countries are predicted to deteriorate to the point of being choked. Originality/value - Existing papers that assessed the effect of decoupling mostly focus on estimating the effect itself through tariff hikes. This paper is meaningful in that it comprehensively analyzed decoupling by adding the effect of technology spillover blockade. In addition, another meaning can be found in that it quantified for the first time that it will deal a huge blow to the extent of choking the East Asian economy as well as China.

• Industry Promotion Research
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• v.8 no.4
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• pp.241-250
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• 2023

In investigating missing persons cases, the focus is on strengthening the efficiency of detectives' work in investigating missing persons cases. Disappearance cases are seen as a problem that directly affects social safety and individual well-being. The research has the following structure. The introduction presents the necessity, scope, and methodology of the study. Next, we analyze the definition, causes, types and actual conditions of disappearance cases. In terms of problems in the process of handling missing persons cases, the initial response process, problems in the response of related agencies after reporting, problems due to the prolongation of the case, and problems due to legal restrictions are analyzed. In the plan to improve the work efficiency of detectives for disappearance cases, the revitalization of public interest investigation networks, strengthening of capacity related to disappearance case investigation, professional public interest detective certification system, and establishment of exception provisions for detective activities are discussed. In the conclusion, we present what is necessary for the activities of public interest detectives specializing in missing persons cases.

• Journal of Contemporary Eastern Asia
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• v.22 no.2
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• pp.1-17
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• 2023

The focus of this research is the practice of journalism in relation to the Behavioural Change Journalism Fellowship (JFPP) during the COVID-19 pandemic in Indonesia. Journalists and curators who are participants in the Behavioural Change Journalism Fellowship received fundings from the state. The Behavioural Change Journalism Fellowship is a unique model because it is the only one in the world in journalism practice that involves state's financial assistance during the COVID-19 pandemic. These fundings from the state for the media lead to dilemmas and controversies. This research uses a qualitative approach and a single holistic case study method. The Behavioural Change Journalism Fellowship was held from May to December 2021, involving 7,276 journalists from 857 media (print, television, radio, and online media) and 26 curators. This study found that during the Behavioural Change Journalism Fellowship, journalism experienced a crisis and lost its function as a control overpower. Giving cash to journalists and curators during the fellowship makes journalism lose its independence and objectivity. The Behavioural Change Journalism Fellowship has degraded or eliminated the function of the press as a watchdog. Incentives for journalists while participating in the Behavioural Change Journalism Fellowship is a long-term investment by the government to co-opt Indonesian media and journalists in the future. On the other hand, the Behavioural Change Journalism Fellowship raises another aspect; the crisis of journalism. Journalism work produced in the Behavioural Change Journalism Fellowship does not reflect the values and principles of journalism. Journalism values, such as independence and impartiality, are absent from the Behavioural Change Journalism Fellowship product.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.17 no.12
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• pp.3383-3397
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• 2023

Scene graphs serve as semantic abstractions of images and play a crucial role in enhancing visual comprehension and reasoning. However, the performance of Scene Graph Generation is often compromised when working with biased data in real-world situations. While many existing systems focus on a single stage of learning for both feature extraction and classification, some employ Class-Balancing strategies, such as Re-weighting, Data Resampling, and Transfer Learning from head to tail. In this paper, we propose a novel approach that decouples the feature extraction and classification phases of the scene graph generation process. For feature extraction, we leverage a transformer-based architecture and design an adaptive calibration function specifically for predicate classification. This function enables us to dynamically adjust the classification scores for each predicate category. Additionally, we introduce a Distribution Alignment technique that effectively balances the class distribution after the feature extraction phase reaches a stable state, thereby facilitating the retraining of the classification head. Importantly, our Distribution Alignment strategy is model-independent and does not require additional supervision, making it applicable to a wide range of SGG models. Using the scene graph diagnostic toolkit on Visual Genome and several popular models, we achieved significant improvements over the previous state-of-the-art methods with our model. Compared to the TDE model, our model improved mR@100 by 70.5% for PredCls, by 84.0% for SGCls, and by 97.6% for SGDet tasks.

• BMB Reports
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• v.57 no.4
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• pp.188-193
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• 2024

Gastric cancer (GC), a leading cause of cancer-related mortality, remains a significant challenge despite recent therapeutic advancements. In this study, we explore the potential of targeting cell surface glucose-regulated protein 94 (GRP94) with antibodies as a novel therapeutic approach for GC. Our comprehensive analysis of GRP94 expression across various cancer types, with a specific focus on GC, revealed a substantial overexpression of GRP94, highlighting its potential as a promising target. Through in vitro and in vivo efficacy assessments, as well as toxicological analyses, we found that K101.1, a fully human monoclonal antibody designed to specifically target cell surface GRP94, effectively inhibits GC growth and angiogenesis without causing in vivo toxicity. Furthermore, our findings indicate that K101.1 promotes the internalization and concurrent downregulation of cell surface GRP94 on GC cells. In conclusion, our study suggests that cell surface GRP94 may be a potential therapeutic target in GC, and that antibody-based targeting of cell surface GRP94 may be an effective strategy for inhibiting GRP94-mediated GC growth and angiogenesis.

• Journal of the Korean Society for Library and Information Science
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• v.58 no.1
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• pp.351-371
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• 2024

This study presented basic data to be collected by the National Library for the Disabled in preparation for the construction of an independent library building and expansion of its scope. Due to legal and practical limitations, the National Library for the Disabled must invest annual budget to collect materials for the disabled and focus on purchasing them. In addition, it is necessary to establish a strategy for comprehensive collection of educational and academic resources, as well as retrospective materials. Accordingly, this study conducted basic research to comprehensively collect resources on the disabled based on the current collection development policy of the National Library for the Disabled. Ten institutions were selected for investigation, and trends in the publication and collection of materials related to disabled people and disability-related data were analyzed based on the data obtained from those institutions. The basic collection catalog presented can serve as foundational data to determine the resources to be collected by the National Library for the Disabled in the future.

• Journal of Environmental Science International
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• v.33 no.1
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• pp.9-16
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• 2024

This study analyzed a survey of residents' awareness of rivers and water spaces that reflected residents' awareness in order to establish a basic park green space plan. Through this, the perception and requirements of rivers and water spaces were analyzed and important information was provided for urban planning and environmental management. As a result of analyzing residents' neutral satisfaction with rivers and their opinions on the frequency of use, role, and purpose, it was confirmed that rivers are recognized as an important part of urban life and contain the potential for development for a better urban environment. . However, considering the dissatisfied response and the relatively low frequency of use, we came to the conclusion that better urban planning and management is needed to meet the needs of residents by improving the river environment and providing various facilities. Based on this, city managers should focus on river management and improvement by actively collecting residents' opinions. Through analysis of the causes of dissatisfied responses, measures such as improving the environment around rivers and waste management should be prepared, and a broad strategy for environmental conservation and utilization should be established by reflecting the diverse expectations and demands of residents. These ongoing efforts are expected to have a positive impact on the sustainability of the city and improvement of residents' quality of life. Additionally, the results of this study will be able to contribute to establishing policies for urban planning and environmental improvement through similar research and analysis in other regions.

• Annals of Occupational and Environmental Medicine
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• v.35
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• pp.10.1-10.10
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• 2023

The purpose of this paper was to review the problems relating to Korea's occupational health services and suggest ways to improve them. Korea can be classified as a welfare state type of conservative corporatism partially interwoven with liberalism. While experiencing compressed economic growth, the economic sectors of developed (excess areas) and developing (deficient areas) countries are interwoven. Therefore, it is necessary to perfect conservative corporatism along with a complementary reinforcement of liberal contents and to apply a multilayered approach focusing on complementing the deficient areas. It is essential to form a national representative indicator related to occupational health, and a strategy for selection and concentration is needed. The proposed central indicator is the occupational health coverage rate (OHCR), which is the number of workers who have applied for mandatory occupational health services under the Occupational Safety and Health Act in the numerator with the total working population in the denominator. This paper proposes ways to raise the OHCR, which is currently at the level of 25%-40%, to 70%-80%, which is the level of Japan, Germany, and France. To achieve this target, it is necessary to focus on small businesses and vulnerable workers. This is an area of market failure and requires the active input of community-oriented public resources. For access to larger workplaces, the marketability of services should be strengthened and personal intervention using digital health resources should be actively attempted. Taking a national perspective, work environment improvement committees with tripartite (labor, management, and government) participation for improvement of the working environment need to be established at the center and in the regions. Through this, prevention funds linked to industrial accident compensation and prevention could be used efficiently. A national chemical substance management system must be established to monitor the health of workers and the general public.