• Bulletin of the Korean Chemical Society
• /
• 제34권6호
• /
• pp.1684-1688
• /
• 2013

A rapid and sensitive method for determining usnic acid of Lethariella cladonioides in rat was established using high performance liquid chromatography (HPLC) quadrupole time-of-flight (QTOF) tandem mass (MS/MS). Rat plasma was pretreated by mixture of acetonitrile and chloroform to precipitate plasma proteins. Chromatographic separation was achieved on a column ($50{\times}2.1$ mm, $5{\mu}m$) with a mobile phase consisting of water (containing $5{\times}10^{-3}$ M ammonium formate, pH was adjusted to 3.0 with formic acid) and acetonitrile (20:80, v/v) at a flow rate of 0.3 mL/min. A tandem mass spectrometric detection with an electrospray ionization (ESI) interface was conducted via collision induced dissociation (CID) under negative ionization mode. The MS/MS transitions monitored were m/z 343.0448 ${\rightarrow}$ m/z 313.2017 for usnic acid and m/z 153.1024 ${\rightarrow}$ m/z 136.2136 for protocatechuic acid (internal standard). The linear range was calculated to be 2.0-160.0 ng/mL with a detection limit of 3.0 pg/mL. The inter- and intra-day accuracy and precision were within ${\pm}7.0%$. Pharmacokinetic study showed that the apartment of usnic acid in vivo confirmed to be a two compartment open model. The method was fully valid and will probably be an alternative for pharmacokinetic study of usnic acid.

• Nuclear Engineering and Technology
• /
• 제55권9호
• /
• pp.3121-3125
• /
• 2023

Neutron conversion detectors that use ¹⁰B-enriched boron carbide are feasible alternatives to ³He-based detectors. We prepared boron carbide films at micron-scale thickness using direct-current magnetron sputtering. The structural characteristics of natural B₄C films, including density, roughness, crystallization, and purity, were analyzed using grazing incidence X-ray reflectivity, X-ray diffraction, X-ray photoelectron spectroscopy, time-of-flight secondary ion mass spectrometry, and scanning electron microscopy. A beam profile test was conducted to verify the practicality of the ¹⁰B-enriched B₄C neutron conversion layer. A clear profile indicated the high quality of the neutron conversion of the boron carbide layer.

• Nuclear Engineering and Technology
• /
• 제54권7호
• /
• pp.2592-2598
• /
• 2022

Research groups in the field of PET instrumentation are studying time-of-flight(TOF) technology to improve the signal-to-noise ratio of PET images. Scintillation light transport and collection plays an important role in improving the coincidence resolving time(CRT) of PET detector based on a pixelated crystal array. Four crystal arrays were designed by the different optical reflection configuration such as external reflectors and surface treatment on the CRT and compared with the light output, energy resolution and CRT. The design proposed in the study was composed of 8 × 8 LYSO crystal array consisted of 3 × 3 × 15 mm³ pixels. The entrance side was roughened while the other five surfaces were polished. Four sides of all crystal pixels were wrapped with ESR-film, and the entrance surface was covered by Teflon-tape. The design provided an excellent timing resolution of 210 ps and improved the CRT by 16% compared to the conventional method using a polishing treatment and ESR-film. This study provided a method for improving the light output and CRT of a pixelated scintillation crystal-based brain TOF PET detector. The proposed configuration might be an attractive detector design for TOF brain PET requiring fast timing performance with high cost-effectiveness.

• 한국항공우주학회지
• /
• 제41권1호
• /
• pp.61-69
• /
• 2013

항공기 비행성 평가 과정에서는 수많은 평가의 반복이 필요하기 때문에 평가 시스템에 있어서 간결하고 명확한 응용 인터페이스가 중요하다. 본 비행성 평가 프로그램은 달라진 트림 조건의 사용자 환경과 함께 효율적인 비행성 평가 사용자 환경을 구현하였다. 그리고 14 항목으로 선별된 무인 고정익기의 비행성 평가 자동화 모듈을 모두 탑재한 종합평가 환경을 구성하였다. 이에 따라 비행제어시스템 개발은 물론 비행성이 고려된 항공기를 개발함에 있어서 검증 및 평가 과정에 소요되는 비용과 시간을 대폭 감소시키고 향후 확장성을 겸비한 유용한 시험 평가 검증 도구로 활용될 수 있을 것으로 사료된다.

• 한국항행학회논문지
• /
• 제27권2호
• /
• pp.162-166
• /
• 2023

본 연구는 부조종사 자격증명 (MPL) 제도 도입을 위한 시범운영 로드맵에 관한 연구로서, MPL 제도의 국내 도입은 기존의 조종사 자격제도와는 다른 역량 (Competency) 기반의 신개념 조종인력 양성 및 자격제도로서 새로운 조종사 교육 및 자격제도이다. 따라서 MPL 제도의 국내 도입은 초기 규정 확보, 훈련사업자 또는 교육생 확보 등의 제반 사항 준비 및 훈련 인프라 구축이 어려울 수 있으므로 MPL 제도의 성공적인 도입을 위해서는 시범운영에 필요한 로드맵이 매우 중요하다. 국내 항공시장에서 MPL 제도가 검증된 훈련프로그램 및 자격체계를 확보하기 위해서는 정부와 항공업계 구성원이 공동으로 참여하여 MPL 훈련프로그램 과정의 점검, 평가 및 개선사항의 도출해내는 국내 비행 환경에 적합한 MPL 제도의 시범운영 로드맵의 중요성을 강조하고자 한다.

• 한국운동역학회지
• /
• 제25권1호
• /
• pp.11-19
• /
• 2015

Objective : The purpose of this study was to analyze the correlation between physical factors (X-factor, X-factor stretch) and club factors (club speed, ball speed, club path, smash factor, vertical launch angle, spin rate, flight time, total length) during impact and it affect on the total distance of the ball during a golf driver swing. Background : There were not enough studies that analyzed the correlation between physical factors(X-factor, X-factor stretch) and club factors(club speed, ball speed, club path, smash factor, launch angle, spin rate, flight time, total length) during a purpose swing to increase total distance. Method : For this study, 9 right handed professional male golfers (KPGA) were chosen. The test subject group used their own drivers and each took a total of 10 swings. These swings consisted of 5 purpose swings to increase total distance and 5 normal swings. Results : The purpose swing to increase total distance showed larger physical factors(X-factor, X-factor stretch) compared to a normal swing however the results were not statistically significant. Total distance increased during a purpose swing as a result of ball and club speed. Conclusion : The results showed that club factors, ball speed and club speed contributed the most in affecting the total distance of the ball during a purpose swing.

• 한국항공우주학회지
• /
• 제34권10호
• /
• pp.80-91
• /
• 2006

위성공학을 전공하는 학생들에게 실질적이고 경험적인 교육을 제공하기 위해 HAUSAT-1과 HAUSAT-2 두 초소형 위성 개발 프로젝트 기반의 다학제간 우주비행체 설계 교육방법을 적용하였다. HAUSAT-1은 국내최초로 개발된 1 kg급의 초소형 피코 위성이다. HAUSAT-2는 25 kg급의 나노 위성으로 현재 준비행 모델(Proto-Flight Model)을 개발 중에 있다. 이들 설계 프로젝트는 연구와 설계 교육의 통합적 기능을 제공함으로써 대학의 고유기능인 과학 및 기술 연구와 설계 교육을 통한 전문 인력양성의 목표를 동시에 이루는 것이 가능하다. 이러한 복합시스템인 우주비행체 설계 교육을 통하여 참여 학생 전원이 우주비행체의 전 시스템 개발 과정을 직간접적으로 경험할 수 있게 하고, 최근 들어 각광을 받고 있는 다학제간 시스템 교육의 활성화를 이룰 수 있다.

• 한국운동역학회지
• /
• 제21권5호
• /
• pp.529-540
• /
• 2011

The purpose of this study was to evaluate the kinematic characteristics of $5^{th}$ and $6^{th}$ hurdle clearances during the final of the 110-m hurdles at the IAAF World Championships, Daegu 2011. To this end, the hurdling motions of the top 4 ranked male hurdlers in the competition were analyzed. A total of 12 cameras were used to record their motions, with a sampling frequency of 120 Hz. The cameras were calibrated using $11{\times}2{\times}1\;m$ control objects that covered all of the lanes (1st~8th lanes). After analyzing all the data, we arrived at the following results. In the take-off phase, all athletes revealed similar take-off times (CT), and similar distances from the take-off to hurdleto (L1) and hurdle to landing (L2). In particular, Turner, ranked $3^{rd}$, had an inconsistent L2 and may need further training to correct it. In the flight phase, Richardson, ranked $1^{st}$, showed the longest flight distance, whereas Xiang, who was ranked $2^{nd}$, showed the highest CG height from the hurdle. For the step patterns, to increase the pitch frequency, Richardson and Xiang used shorter 3-step lengths than Turner and Oliver.

• 한국지역지리학회지
• /
• 제21권1호
• /
• pp.39-61
• /
• 2015

이 논문은 도시 연계성에 관한 문헌들을 검토한 후 다중심도시지역의 개념과 분석기법을 제시하고, 이를 활용하여 영남권 도시들 간 화물통행량을 분석하여 도시 연계성과 다중심성을 고찰하고자 한다. 분석 결과, 영남권의 도시 네트워크는 흐름의 대칭성(즉 유입과 유출 통행량의 차이)에 있어 도시별로 상당한 차이를 보이지만, 엔트로피 지수로 보면 상대적으로 분산적인 흐름을 나타내고 있다. 또한 지배력 지수로 보면, 영남권 도시네트워크는 수도권에 비해 훨씬 다중심적(즉 비계층적) 특성을 보인다. 그러나 부산과 울산은 상대적으로 지배력 지수가 높고 이 도시들에 의존하는 연계도시들이 많은 반면, 대구는 지배력 지수가 상대적으로 낮고, 의존적 연계도시들의 수도 적게 나타난다. 결론적으로 제조업 부문별 화물 네트워크는 1위 도시인 부산을 중심으로 흐름이 집중하는 양상을 보이지만, 전반적으로 영남권 도시지역은 다중심도시지역의 특성을 상당히 보인다는 점에서, 다중심적 지역발전 정책이 권장될 수 있다.

• 한국운동역학회지
• /
• 제20권3호
• /
• pp.311-318
• /
• 2010

This study examined the double piked dismount among the landing techniques of parallel bars based on three-dimensional motion analysis. Four male national gymnasts were the subjects. This study was performed to provide quantitative data highlighting players strengths and weaknesses to enable more stable landing technique. The variables analyzed were the position and velocity of center of gravity(CG) and angles of shoulder joints, hip joints, and trunk. The results are as follows: S1 secured the height of flight with fast vertical rise. After the easy spin in the air, he conducted a stable landing maintaining a proper hip joints angle. S2, S3, and S4, however, began the backward somersault already before leaving the bars, so they moved backward greatly making it more difficult to achieve a higher flight path. As a result, they couldn't control the velocity of their backward movement at landing. For a stable landing, they have to maintain the negative shoulder angle when rising, minimize both antero-posterioror side-to-side movements by doing a strong tap using hip joints, to secure the height of flight before the somersault. Results also show that at the descent, they should conduct rapid spinning by increasing their shoulder and hip joints to the maximum while controlling their velocity.