• 한국엔터테인먼트산업학회논문지
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• 제14권6호
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• pp.91-107
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• 2020

본 연구는 유튜브 커버음악 채널의 성공 요인에 대하여 정량적 연구를 하고자 하는 데 목적을 가지고 있다. 그 과정에서 기존의 정성적 연구 결과를 바탕으로 커버음악 채널의 특성을 측정하는 측정도구를 구성하고 검정하는 것이 두 번째 목적이다. 이를 위해 최근 사례연구에서 제시한 커버음악 채널의 성공 요인을 후기기술수용모형과 융합하였다. 커버음악 채널의 콘텐츠, 영상, 크리에이터, 상호작용성, 홍보라는 5가지 특성을 중심으로 척도화하여 신뢰성과 타당성 검증을 거치면서 정량화 가능성을 탐색하고 이 결과물과 후기기술수용모형에서 제시하는 중요 변인들과의 인과관계를 검증하였다. 본 연구 결과 첫째, 콘텐츠 특성은 이용자들의 정서적 즐거움에 영향을 주지 않는 것으로 밝혀졌다. 또한, 기존 사례에서 제시된 채널 특성 요인 5가지 중에서 크리에이터 특성이 정서적 즐거움에 가장 큰 영향을 미치는 요인으로 확인되었다. 둘째, 요인분석 과정에서 유튜브 커버음악 채널 특성 중 콘텐츠 특성과 영상 특성이 한 요인으로 적재되어 통합되었다. 셋째, 만족과 지속사용의도 또한 한 요인으로 통합되었다. 이러한 연구 결과를 바탕으로 커버음악 채널 운영자들은 크리에이터의 매력을 돋보이게 하는 영상콘텐츠 제작이 필요하다. 아울러 이용자들과의 상호작용과 홍보에 노력해야 한다는 것을 제시한다.

• Journal of Microbiology
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• 제45권6호
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• pp.528-533
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• 2007

In a previous study we generated an anti-Hepatitis B Virus (HBV) preS1 humanized antibody (HzKR127) that showed in vivo HBV-neutralizing activity in chimpanzees. However, the antigen-binding affinity of the humanized antibody may not be sufficient for clinical use and thus affinity maturation is required for better therapeutic efficacy. In this study, phage display technique was employed to increase the affinity of HzKR127. All six amino acid residues (Glu95-Tyr96-Asp97-Glu98-Ala99-Tyr100) in the heavy (H) chain complementary-determining region 3 (HCDR3) of HzKR127 were randomized and phage-displayed single chain Fv (scFv) library was constructed. After three rounds of panning, 12 different clones exhibiting higher antigen-binding activity than the wild type ScFv were selected and their antigen-binding specificity for the preS1 confirmed. Subsequently, five ScFv clones were converted to whole IgG and subjected to affinity determination. The results showed that two clones (B3 and A19) exhibited an approximately 6 fold higher affinities than that of HzKR127. The affinity-matured humanized antibodies may be useful in anti-HBV immunotherapy.

• Asian-Australasian Journal of Animal Sciences
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• 제17권9호
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• pp.1309-1314
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• 2004

The red carotenoid, astaxanthin was studied to improve the meat quality of broiler chickens. Astaxanthin pigmented chickens and delayed oxidation of lipid in them. Two sources of astaxanthin were used to pigment broiler chickens in a five-wk feeding trial: biological astaxanthin (BA) from the red yeast, Xanthophyllomyces dendrorhous, and chemical astaxanthin (CA) from chemical synthesis. The concentrations of CA (45 mg/kg feed) and BA (22.5 mg/kg feed) were set to give similar levels of pigmentation. The colorimetric values (a and b) of breast muscles were significantly changed by astaxanthin (p${\leq}$0.01). Absorption and accumulation of BA were higher than those of CA, probably due to the high contents of lipids in the yeast (17%). Lipid peroxide formation in skin was significantly decreased by astaxanthin (p${\leq}$0.05). This result indicated that the production of lipid peroxides in the carcasses of broiler chickens during storage could be delayed by astaxanthin. Therefore, astaxanthin could be used as an antioxidant as well as a colorant for broiler chickens.

• Journal of Applied Biological Chemistry
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• 제50권1호
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• pp.17-21
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• 2007

1-C-(p-Hydroxyphenyl)-glycerol (1) was isolated and purified by column chromatography and recrystallization from the rhizome of Trichosanthes kirilowii, firstly in this species. Isolated compound showed inhibitory effects on the growth of five bacteria (Bacillus cereus, Escherichia coli, Streptococcus faecalis, etc) completely at the concentration higher than 10 ppm as well as delayed the growth of three bacteria (Bacillus substilis, Staphylococcus aureus, Pseudomonas aeroginosa) at the concentration of 25 ppm for 60 h. Moreover, this compound showed potent antioxidant activity against DPPH radical ($IC_{50}$ = 56.0 ppm)

• Journal of Evidence-Based Herbal Medicine
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• 제2권1호
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• pp.25-31
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• 2009

The origin and description of the Herba Plantaginis was contemporarily analyzed (family names, scientific names, target regions, preparation, etc.) by comparison to enormous literature in addition to the external features written in the existing books on traditional Korean medicine. Also, galenical description were analyzed in connection with external morphology, internal morphology, microscopy and five senses. The official documents and ancient documents of other countries were reviewed. The technical books on herbage, published in the country and other countries, were compared with each other. Also, on-the-spot surveys were made to learn specialists' know-how. The description of the collected drugstuffs were analyzed in connection with external morphology (size, color, etc.), internal morphology and microscopy. The results of this study can be applied to the publicity and education of galenical test agencies; the effective management of foods and drugs; the improvement of public medical service; the publicity of galenical safety.

• 동의생리병리학회지
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• 제16권5호
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• pp.873-880
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• 2002

We study on the significance and application of the whole body form diagnosis. The results were as follows; The general form diagnosis is the method to observe the individual physiology and pathology. The phase of thinking, the current and activity of KI, the pattern of general form diagnosis have organic relations with the symptoms. The general form diagnosis is made up the principle of the imaging phase, therefore it must make synthetic union the differentiation of syndromes. The general form diagnosis of NAE GYEONG shows the typical phases and it is divided with the sight of YIN YANG and Five-Element. The general form diagnosis of SEOP GAE is practiced the theory of constitution's demonstration before the understanding of symptoms. Then JANG NAM tried the type of constitution's demonstration. The general form diagnosis of DONG MU becomes the diagnostic root of constitution's demonstration in four type constitution theory.

• 한국환경과학회지
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• 제21권7호
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• pp.837-843
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• 2012

The aims of this study were to investigated the occurrence of caffeine and carbamazepine in Nakdong river basin (8 mainstreams and 2 tributaries) and the behavior of caffeine and carbamazepine under drinking water treatment processes (conventional and advanced processes). The examination results showed that caffeine was detected at all sampling sites (5.4~558.5 ng/L), but carbamazepine was detected at five sampling sites (5.1~79.4 ng/L). The highest concentration level of caffeine and carbamazepine in the mainstream and tributaries in Nakdong river were Goryeong and Jinchun-cheon, respectively. These pharmaceutical products were completely removed when they were subject to conventional plus advanced processes of drinking water treatment processes. Conventional processes of coagulation, sedimentation and sand-filtration were not effective for their removal, while advanced processes of ozonation and biological activated carbon (BAC) filtration were effective. Among these pharmaceuticals, carbamazeoine was more subject to ozonation than caffeine.

• 대한한방부인과학회지
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• 제25권3호
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• pp.157-167
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• 2012

Objectives: It is not yet clear wheather myomectomy for uterine myomas raises the pregnancy rate or not. And myomectomy has the risk of side effects and reducing pregnancy rate by causing tubal disorders, pelvic adhesions, endometriosis and so on. Therefore less invasive treatment to patients with uterine myoma who want to be pregnant is necessary. Methods: In this study, the patients who had uterin myoma were treated by oriental medical treatments such as herbal medication, acupuncture and moxibustion therapy. Results: After oriental medical treatments, their menstrual condition was improved and size of their myoma was decreased. And they were pregnant within two to five months. Conclusions: This case report shows that the oriental medical treatment is less invasive for uterine myoma and that is effective for patients with uterine myoma who want to be pregnant.

• 혜화의학회지
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• 제23권1호
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• pp.21-55
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• 2014

Objectives : This report describes the original references of 154 formulas related to the use of Rhei Rhizoma main blended from Dongeuibogam. Methods : This study analyzes the original references of 154 formulas including Rhei Rhizoma as a key component in Dongeuibogam. Results : There were five types as follows: 1.There is no exact match between 154 formulas in Dongeuibogam and the original formulas in references. 2. Case that could not found the original formula in reference: 22%. 3. Case that the citation is the similar to the original reference: 4%. 4. Case that the citation is not same to expression but contents basically: 73%. 5. Case of addition of content: 1% Conclusions : Most formulas related to the use of Rhei Rhizoma main blended from Dongeuibogam are similar to the contents in the original references. But we can find that Heo Jun, who writes Dongeuibogam, modifies the contents for his intention of editing, idea and situation in Korea.

• 대한의용생체공학회:의공학회지
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• 제33권1호
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• pp.1-7
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• 2012

Hemorrhagic shock is a common cause of death in emergency rooms. Early diagnosis of hemorrhagic shock makes it possible for physicians to treat patients successfully. Therefore, the purpose of this study was to select an optimal survival prediction model using physiological parameters for the two analyzed periods: two and five minutes before and after the bleeding end. We obtained heart rates, mean arterial pressures, respiration rates and temperatures from 45 rats. These physiological parameters were used for the training and testing data sets of survival prediction models using an artificial neural network (ANN) and support vector machine (SVM). We applied a 5-fold cross validation method to avoid over-fitting and to select the optimal survival prediction model. In conclusion, SVM model showed slightly better accuracy than ANN model for survival prediction during the entire analysis period.