Journal of Applied Biological Chemistry

The Korean Society for Applied Biological Chemistry (한국응용생명화학회)
권호 표지

Antibacterial and Radical Scavenging Activities of 1-C-(p-Hydroxyphenyl)-Glycerol from Trichosanthes kirilowii

  • Jang, Ki-Chang (National Institute of Subtropical Agriculture, R.D.A.) ;
  • Lee, Jin-Hwan (Yeongnam Agricultural Research Institute, National Institute of Crop Science, R.D.A.) ;
  • Kim, Seong-Cheol (National Institute of Subtropical Agriculture, R.D.A.) ;
  • Song, Eun-Young (National Institute of Subtropical Agriculture, R.D.A.) ;
  • Ro, Na-Young (National Institute of Subtropical Agriculture, R.D.A.) ;
  • Moon, Doo-Young (National Institute of Subtropical Agriculture, R.D.A.) ;
  • Um, Yeong-Cheol (National Institute of Subtropical Agriculture, R.D.A.) ;
  • Park, Ki-Hun (Division of Applied Life Science (BK21 Program), Environmental Biotechnology National Core Research Center, Research Institute of Life Science, Gyeongsang National University)
  • Published : 2007.03.30
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Abstract

1-C-(p-Hydroxyphenyl)-glycerol (1) was isolated and purified by column chromatography and recrystallization from the rhizome of Trichosanthes kirilowii, firstly in this species. Isolated compound showed inhibitory effects on the growth of five bacteria (Bacillus cereus, Escherichia coli, Streptococcus faecalis, etc) completely at the concentration higher than 10 ppm as well as delayed the growth of three bacteria (Bacillus substilis, Staphylococcus aureus, Pseudomonas aeroginosa) at the concentration of 25 ppm for 60 h. Moreover, this compound showed potent antioxidant activity against DPPH radical ($IC_{50}$ = 56.0 ppm)

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