• 제목/요약/키워드: 1-C-(p-hydroxyphenyl)-glycerol

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Antibacterial and Radical Scavenging Activities of 1-C-(p-Hydroxyphenyl)-Glycerol from Trichosanthes kirilowii

  • Jang, Ki-Chang;Lee, Jin-Hwan;Kim, Seong-Cheol;Song, Eun-Young;Ro, Na-Young;Moon, Doo-Young;Um, Yeong-Cheol;Park, Ki-Hun
    • Journal of Applied Biological Chemistry
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    • 제50권1호
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    • pp.17-21
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    • 2007
  • 1-C-(p-Hydroxyphenyl)-glycerol (1) was isolated and purified by column chromatography and recrystallization from the rhizome of Trichosanthes kirilowii, firstly in this species. Isolated compound showed inhibitory effects on the growth of five bacteria (Bacillus cereus, Escherichia coli, Streptococcus faecalis, etc) completely at the concentration higher than 10 ppm as well as delayed the growth of three bacteria (Bacillus substilis, Staphylococcus aureus, Pseudomonas aeroginosa) at the concentration of 25 ppm for 60 h. Moreover, this compound showed potent antioxidant activity against DPPH radical ($IC_{50}$ = 56.0 ppm)