• Title/Summary/Keyword: Fisher Effect

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Effect of 2-6 weeks of systemic steroids on bone mineral density in children

  • Kuniyil, Athira;Pal, Somdipa;Sachdev, Namrita;Yadav, Tribhuvan Pal
    • Clinical and Experimental Pediatrics
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    • v.65 no.5
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    • pp.254-261
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    • 2022
  • Background: The use of systemic steroids for 6+ weeks in children is associated with decreased bone mineral content (BMC) and density (BMD). However, the effects of a shorter duration of use on BMD are unknown. Purpose: To determine the effect of the use of systemic steroids for 2-6 weeks on BMD and BMC in pediatric patients. Methods: Twenty-five pediatric patients (21 with tuberculosis, 2 with systemic juvenile idiopathic arthritis, 1 with inflammatory bowel disease, 1 with autoimmune hemolytic anemia) who received systemic steroids for 2-6 weeks and 25 age- and sex-matched controls were enrolled. BMC, BMD, and z scores of the whole body (WB), lumbar spine (LS), nondominant distal radius (DR), and total body less the head (TBLH) were determined by dual-energy x-ray absorptiometry at baseline, the end of steroid therapy or 6 weeks (whichever was earlier; first follow-up), and at the end of 3 months from baseline (second follow-up) in patients and at baseline in controls. The values were adjusted for confounding variables. Continuous and categorical variables were compared using Student t test and the chi-square test or Fisher exact test, respectively. Pairwise comparisons employed Bonferroni correction. Results: Statistically significant decreases in BMC, BMD, and all z scores were observed. BMC declined by 5.37%, 2.08%, 1.82%, and 2.27%, and 11.42%, 3.75%, 3.34%, and 4.17% for WB, LS, DR, and TBLH, respectively, at the first and second follow-ups, respectively. Similarly, BMD declined by 2.01%, 2.31%, 2.18%, and 1.70% and 4.59%, 3.76%, 3.14%, and 3.50% for the WB, LS, DR, and TBLH, respectively, at the first and second follow-ups, respectively. A significant negative correlation was found among bone densitometric parameters, duration, and cumulative dose. Conclusion: The use of systemic steroids for 2-6 weeks in pediatric patients decreased the BMD and BMC of trabecular and cortical bones, an effect that persisted after discontinuation.

Conventional and digital impressions for complete-arch implant-supported fixed prostheses: time, implant quantity effect and patient satisfaction

  • Pereira, Ana Larisse Carneiro;Medeiros, Vitoria Ramos;Campos, Maria de Fatima Trindade Pinto;Medeiros, Annie Karoline Bezerra de;Yilmaz, Burak;Carreiro, Adriana da Fonte Porto
    • The Journal of Advanced Prosthodontics
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    • v.14 no.4
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    • pp.212-222
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    • 2022
  • PURPOSE. To evaluate and compare the effect of impression type (conventional vs digital) and the number of implants on the time from the impressions to the generation of working casts of mandibular implant-supported fixed completearch frameworks, as well as on patient satisfaction. MATERIALS AND METHODS. 17 participants, 3 or 4 implants, received 2 types of digital impression methods (DI) and conventional (CI). In DI, two techniques were performed: scanning with the scan bodies (SC) and scanning with a device attached to the scan bodies (SD) (BR 10 2019 026265 6). In CI, the making of a solid index (SI) and open-tray impression (OT) were used. The outcomes were used to evaluate the time and the participant satisfaction with conventional and digital impressions. The time was evaluated through the timing of the time obtained in the workflow in the conventional and digital impression. The effect of the number of implants on time was also assessed. Satisfaction was assessed through a questionnaire based on seven. The Wilcoxon test used to identify the statistical difference between the groups in terms of time. The Mann-Whitney test was used to analyze the relationship between the time and the number of implants. Fisher's test was used to assess the patient satisfaction (P<.05). RESULTS. The time with DI was shorter than with CI (DI, $\tilde{x}=02:58$; CI, $\tilde{x}=31:48$) (P<.0001). The arches rehabilitated with 3 implants required shorter digital impression time (3: $\tilde{x}=05:36$; 4: $\tilde{x}=09:16$) (P<.0001). Regarding satisfaction, the DI was more comfortable and pain-free than the CI (P<.005). CONCLUSION. Digital impressions required shorter chair time and had higher patient acceptance than conventional impressions.

Effect of Majoon Idraare Haiz in Polycystic Ovarian Syndrome - A pilot study

  • Firdose, Kouser fathima;Begum, Wajeeha
    • CELLMED
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    • v.12 no.1
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    • pp.3.1-3.7
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    • 2022
  • Background & Objectives: Polycystic ovarian syndrome (PCOS) is one of the commonest endocrine abnormality in women of reproductive age affecting from 4% - 21% of the reproductive women and is characterized by chronic anovulation and hyperandrogenism. The aim of the study was to evaluate the effect of majoon idraare haiz in menstrual regulation and morphological changes in ovaries in poly cystic ovarian syndrome. Methods: A Pilot study was carried out in the department of Ilmul qabalat wa amraze niswan, National institute of unani medicine, hospital, Bengaluru. Fifteen Patients of PCOS aged 18-35 diagnosed using Rotterdam criteria were included in the study. Patients with insulin sensitizing treatment within 3 months, hormonal treatment and those with h/o diabetes mellitus, hypertension, pregnant and lactating women were excluded.Majoon idraare haiz was administered orally at a dose of 10 g with 20 ml arqbed mushk once daily from fifth day of cycle for 21 days for three consecutive cycles. Primary outcome measure was menstrual regularity while changes in USG pelvis(normal ovarian morphology) was considered as secondary outcome measure. In addition, duration of flow and changes in basal metabolic index (BMI), modified Ferriman Gallwey (mFG) score, acanthosis nigricanswere observed. Data were analyzed using, ANOVA, paired student 't' test, fisher exact test. Results: Changes in duration of cycle, duration and amount of flow was achieved in 93.3% patients with p<0.0001 and 46.6% patients showed normal findings on pelvic ultrasonography with p=0.006. In addition, significant changes were also observed in BMI, hirsutism and acanthosis nigricans with p value of 0.0001, p=0.003 and p=0.009 respectively Conclusion: Majoonidraare haiz can be used as an effective alternative in management of PCOS patients. It has significant effect on menstrual regulation and changes in polycystic ovarian morphology to normal.

The Histopathology of Hyeungbangjihwang-tang Extracts on the Liver Cirrhosis of Fisher 344 Rats Induced by Long Time Carbon Tetrachloride Injection. (사염화탄소의 장기(長期) 투여(投與)로 유발된 백서(白鼠) 간경변(肝硬變)에 대한 형방지황탕(荊防地黃湯)의 조직병리학적 영향)

  • Kim, Seong-Mo
    • The Journal of Internal Korean Medicine
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    • v.29 no.2
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    • pp.375-384
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    • 2008
  • Objective : This study was carried out to investigate the effects of oral administration of Hyeungbangjihwang-tang (HBJHT) on the liver cirrhosis of rats induced by Carbon tetrachloride for 10 weeks. Method : The histopathological changes were observed. The HBJHT extracts were daily dosed at 50, 100 and 200mg/kg for 12 weeks. Results : Severe hepatocellular necrosis and ballooning, hyperplasia of connective tissue, subdued reduction of hepatic lobule, and hyperplasia of bile duct in portal triad were dramatically decreased in the HBJHT-treated group compared to that of the Carbon tetrachloride-treated control group in histopathological observation. The diameter of hepatic lobules was significantly enlarged in the HBJHT-treated group compared to that of the Carbon tetrachloride-treated control group, and the amounts of connective tissue, degenerative cells and bile ducts were significantly and dose-dependently decreased. Conclusion : It is concluded that HBJHT has a significant recovering effect on the liver of rats induced by carbon tetrachloride.

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A Study on the Perception of the Myopia in Children's Mother (학령초기아동 어머니의 근시 인식)

  • Kim, Jin-Hyang;Yang, Soon-Ok
    • The Journal of Korean Academic Society of Nursing Education
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    • v.11 no.2
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    • pp.214-221
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    • 2005
  • Purpose: This study was to investigate the perception of the myopia in early school-aged children's mother and develope myopia preventive education program. Method: Data was collected from June 1th to 24th, 2003. The sample group(two elementary schools in A city)consisted of 105students mother with normal vision(naked vision 1.0 or more), 105 students mother with subnormal vision(0.7 or less). The data was analyzed using S.A.S. For the test of homogeneity and significance of variable, Fisher's Exact test and Student's t-test were used. Results: 1. There was significant difference in perception of being changed the children's eyesight between normal and myopia group(t=7.86, p=.0492). 2. High scores of cause of myopia were distance from TV or computer to viewer and time of watching TV or using computer in both groups. 3. There was significant difference in perception score of cause of myopia in the myopia group was 13.26, and 18.04 in the normal group(t=3.01, p=0.003). Especially in the unbalanced and regulated diet, regulated exercise, distance of eyes reading books and illumination, normal group had more perception score than myopia group. Conclusion: A myopia education program for children and parents should be planed and the effect be verified.

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The Effect of Tai Chi Self Help Group Program for Hemophilic Arthritis Patients (혈우병관절염 수술환자를 위한 타이치자조관리 프로그램 효과)

  • Bak, Won-Sook;Yoo, Myung-Chul;Kang, Hyun-Sook
    • Journal of muscle and joint health
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    • v.19 no.1
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    • pp.71-83
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    • 2012
  • Purpose: The purpose of this study was to develop and evaluate the effects of Tai Chi Self-help program for Hemophilic Arthritis Patients. Method: A quasi-experimental design was used. The subjects were 48 patients who underwent orthopedic surgery (24 experimental group, 24 control group). The subjects of experimental group were participated in the Tai Chi self-help group program in which 16 times for 8 weeks. The program consisted of health education on hemophilia, Tai Chi exercise, and workshop and its outcomes have been evaluated on WOMAC(Western Ontario and McMaster scale), mobility, pain, fatigue, muscle strength, depression, and quality of life(SF-36). The obtained data were analyzed by using the t-test or Fisher's exact test of PASW 18.0. Results: 1) The score of WOMAC, pain, fatigue, and depression decreased significantly in the experimental group as compared to the control group. 2) The score of mobility, muscle strength, and quality of life increased significantly in the experimental group as compared to the control group. Conclusion: Considering these research results, the program could be useful to improve joint movement, strength and psychological condition for patient with hemophilic arthritis, particularly in those who underwent orthopedic surgery.

Evidence-based use of cold for plantar fasciitis

  • Laymon, Michael S.;Petrofsky, Jerrold S.;Alshammari, Faris;Fisher, Stacy
    • Physical Therapy Rehabilitation Science
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    • v.2 no.2
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    • pp.75-80
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    • 2013
  • Objective: The purpose of this study was to examine the effect of cold applied the night before or in the morning on pain and symptoms of plantar fasciitis. Design: Experimental study. Methods: Thirty subjects with plantar fasciitis were recruited for this study. Subjects with plantar fasciitis either had no intervention, cold applied (20 minutes) at night before bed, or 20 minutes in the morning upon wakening. Plantar fascia tenderness and pain were evaluated. There were ten subjects in each group. Measures included visual analog scale, plantar facial thickness via high resolution ultrasound, algometer measure, and range of motion of the ankle and foot. There were 3 groups of 10 subjects, control (no intervention), cold the night before bed, and cold in the morning before rising. Results: The greatest relief of symptoms was cold used at bedtime the night before the measurements. Cold used in the morning was not as effective as cold used in the evening before bed. Cold use reduced the thickness of the plantar fascia and irritation. There was a 13% reduction in plantar fascia thickness with cold the night before (p<0.05), a 44% reduction in pain and an 86 % increase in the force that could be applied to the bottom of the foot without pain (p<0.05). Conclusions: Cold applied for 20 minutes prior bedtime is effective for reduced symptomology caused by plantar fascia inflammation.

Effects of a Workbook Program on the Perceived Stress Level, Maternal Role Confidence and Breast Feeding Practice of Mothers of Premature Infants (워크북 프로그램이 미숙아어머니의 스트레스, 모성역할 자신감, 모유수유 실천에 미치는 효과)

  • Jang Yung-sook
    • Journal of Korean Academy of Nursing
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    • v.35 no.2
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    • pp.419-427
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    • 2005
  • Purpose: The purpose of this study was to identify the effects of a workbook program on percieved stress levels, maternal role confidence and breastfeeding practices of mothers of premature infants. Method: This study employed a quasi-experimental non-equivalent pre-and-post test to compare the two groups. Data was collected from 32 subjects from March 10. to September 5, 2003 at an NICU located in S. city. In the sample, fifteen mothers were in the experimental group and seventeen were in the control group. A workbook program was provided twice during a period from two-three days after the baby's admission to one week after the first intervention. The instruments used were the PSS and self confidence scale. Data was analyzed by means of frequency, SD, $x^2-test$, Fisher's exact test, Mann-Whitney test, and the Wilcoxon signed rank test. Result: There was a significant difference in perceived stress levels between the experimental and control group (U=2.366, p=.018). There was not a significant difference in maternal role confidence between the two groups (U=1.002, p=.316). There was a significant difference in breastfeeding practice between the two groups ($x^2=4.910$, p=.035). Conclusion: It is concluded that a program using a workbook has a positive effect on decreasing the perceived stress level and increasing breastfeeding practice.

The Effects of Aromatherapy on Pain, Depression, and Life Satisfaction of Arthritis Patients (관절염환자의 동통, 우울 및 삶의 만족도에 대한 아로마 요법)

  • Kim, Myung-Ja;Nam, Eun-Sook;Paik, Seun-In
    • Journal of Korean Academy of Nursing
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    • v.35 no.1
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    • pp.186-194
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    • 2005
  • Purpose: The purpose of this study was to investigate the effect of aromatherapy on pain, depression, and feelings of satisfaction in life of arthritis patients. Method: This study used a quasi-experimental design with a non-equivalent control group, pre-and post-test. The sample consisted of 40 patients, enrolled in the Rheumatics Center, Kangnam St. Mary's Hospital, South Korea. The essential oils used were lavender, marjoram, eucalyptus, rosemary, and peppermint blended in proportions of 2:1:2:1:1. They were mixed with a carrier oil composed of almond (45%), apricot(45%), and jojoba oil(10%) and they were diluted to 1.5% after blending. The data were analyzed using an 2-test, Fisher's exact test, t-test and paired t-test. Result: Aromatherapy significantly decreased both the pain score and the depression score of the experimental group compared with the control group. However, aromatherapy didn't increase the feeling of satisfaction in life of the experimental group compared with the control group. Conclusion: The result of this study clearly shows that aromatherapy has major effects on decreasing pain and depression levels. Based on our experiment's findings, we suggest that aromatherapy can be a useful nursing intervention for arthritis patients.

Effects of Resistance Exercise using Elastic Band on Range of Motion, Function and Shoulder Pain among Patients with Rotator Cuff Repair (탄성밴드를 이용한 저항운동이 회전근개봉합술 환자의 견관절가동범위와 기능 및 통증에 미치는 효과)

  • Sim, Jae Ok
    • Korean Journal of Adult Nursing
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    • v.28 no.5
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    • pp.491-500
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    • 2016
  • Purpose: The purpose of this study was to examine the effect of resistive exercise using an elastic band on range of motion, function and shoulder pain. Methods: Forty two subjects who had rotator cuff surgery were assigned either to a treatment or a comparison group, twenty one each. Following a six week period after surgery those in the treatment group participated in resistant exercise using an elastic band for four weeks. The subjects in the comparison group did not participate in the exercise program. The goniometer measured range of motion, a modified tool measured function, and a self report numerical rating scale measured pain. The data were analyzed using $x^2$ test, Fisher's exact, t-test and the Mann-Whitney Test. Results: Although not statistically significant, there was a trend that more subjects in the treatment group had increased range of motion. There was a statistically significance among the treatment group in terms of increased function (p=.015). Further the treatment group reported less pain that those in the comparison group (p<.001). Conclusion: The findings support that resistance exercise is an effective strategy for patients with rotator cuff repair.