• Transactions of the Korean Society of Mechanical Engineers B
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• v.29 no.5 s.236
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• pp.590-598
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• 2005

The present study has been conducted to investigate the effect of discrete ribs and rotation on heat/mass transfer characteristics in a two-pass square duct with $90^{\circ}-rib$ turbulators. The rib turbulator has a square cross section of 1.5 mm. The rib height-to-hydraulic diameter ratio $({e/D_{h})$ is 0.056, and the rib pitch-to-rib height ratio (p/e) is 10. The gap width is the same as the rib height. The rotation number ranges from 0.0 to 0.2 while Reynolds number is fixed to 10,000. In a stationary duct, the heat/mass transfer on the surfaces with discrete ribs is enhanced because the gap flow promotes local turbulence and flow mixing near the ribbed surface. In a rotating duct, the gap flow affects differently the heat/mass transfer on leading and trailing surfaces with discrete ribs. On the leading surface of the first pass, heat/mass transfer is increased due to the gap flow. On the trailing surface of the first pass, however, heat/mass transfer is decreased because the gap flow disturbs reattachment of main flow. The phenomenon, that is, the difference of heat transfer between the leading and the trailing surfaces is distinctly presented by rotation.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.29 no.6 s.237
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• pp.737-746
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• 2005

The present study investigates heat/mass transfer and flow characteristics in a ribbed rotating passage with turning region. The duct has an aspect ratio (W/H) of 0.5 and a hydraulic diameter ($D_h$) of 26.67 mm. Rib turbulators are attached in the cross arrangement on the leading and trailing surfaces of the passage. The ribs have a rectangular cross section of $2\;mm\;(e){\times}\;mm\;(w)$ and an attack angle of $70^{\circ}$. The pitch-to-rib height ratio (p/e) is 7.5, and the rib height-to-hydraulic diameter ratio ($e/D_h$) is 0.075. The rotation number ranges from 0.0 to 0.20 while the Reynolds number is constant at 10,000. To verify the heat/mass transfer augmentation, internal flow structures are calculated for the same conditions using a commercial code FLUENT 6.1. The heat transfer data of the smooth duct for various Ro numbers agree well with not only the McAdams correlation but also the previous studies. The cross-rib turbulators significantly enhance heat/mass transfer in the passage by disturbing the main flow near the surfaces and generating one asymmetric cell of secondary flow skewing along the ribs. Because the secondary flow is induced in the first-pass and turning region, heat/mass transfer discrepancy is observed in the second-pass even for the stationary case. When the passage rotates, heat/mass transfer and flow phenomena change. Especially, the effect of rotation is more dominant than the effect of the ribs at the higher rotation number in the upstream of the second-pass.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.28 no.8 s.227
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• pp.910-920
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• 2004

The heat/mass transfer characteristics in a rotating two-pass duct with and without rib turbulators are investigated in the present study. The square duct has a hydraulic diameter ($D_h$) of 26.7 mm, and $1.5\;mm{\times}1.5\;mm$ square $90^{\circ}$-rib turbulators are attached on the leading and trailing walls. The pitch-to-rib height ratio (p/e) is 10. The Reynolds number based on the hydraulic diameter is kept constant at 10,000 to exclude the Reynolds effect, and the rotation number is varied from 0.0 to 0.20. In the smooth duct, the curvature of the $180^{\circ}$-turn produces Dean vortices that enhance heat/mass transfer in the post-turn region. When rib turbulators are installed, heat/mass transfer is augmented 2.5 times higher than that of the smooth duct since the main flow is turbulated by reattaching and separating in the vicinity of the duct surfaces. The duct rotation results in heat/mass transfer discrepancy so that Sherwood number ratios are higher on the trailing surface in the first-pass and on the leading surface in the second-pass. In the turning region, Dean vortices shown in the stationary case transform into one large asymmetric vortex cell, and subsequent heat/mass transfer characteristics also change. As the rotation number increases, the heat/mass transfer discrepancy enlarges.

• Journal of the Korean Geophysical Society
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• v.2 no.2
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• pp.143-152
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• 1999

We have studied a denoising technique involving wavelet transform for improving the quality of geophysical data during the preprocessing stage. To assess the effectiveness of this technique, we have made synthetic data contaminated by random noises and compared the results of denoising with those obtained by conventional low-pass filtering. The low-pass filtering of the sinusoidal signal having a sharp discontinuity between the first and last sample values shows apparent errors related to Gibbs' phenomena. For the case of bump signal, the low-pass filtering induces maximum errors on peak values by removing some high-frequency components of signal itself. The wavelet transform technique, however, denoises these signals with much less adverse effects owing to its pertinent properties on locality of wavelet and easy discrimination of noise and signal in the wavelet domain. The field data of gravity tide are denoised by using soft threshold, which shrinked all the wavelet coefficients toward the origin, and the G-factor is determined by comparing the denoised data and theoretical data.

• Journal of Pharmaceutical Investigation
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• v.31 no.4
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• pp.265-271
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• 2001

In order to elucidate the influence of intestinal and hepatic first-pass effect on the pharmacokinetics of triflusal, the biotransformation of triflusal in the gastrointestinal tract and liver was designed. Moreover, we tried to establish an HPLC method applicable for bioassay and available to pharmacokinetics, not only with the simultaneous determination of triflusal and its active metabolite, 2-hydroxy-4-trifluoromethyl benzoic acid (HTB), but also with improving sensitivity. After the administration of triflusal (10 mg/kg) and HTB (10 mg/kg) into femoral vein, portal vein (only triflusal) and oral route (only triflusal), pharmacokinetic parameters were investigated from the plasma concentration-time profiles of triflusal and HTB in rats. An HPLC method was developed for the simultaneous determination of triflusal and HTB in rat plasma, urine and bile. The HPLC analysis was carried out using a C18 column and acetonitrile-methanol-water (25:10:65, v/v/v) as the mobile phase and UV detection at 234 nm. Furosemide was used as the internal standard. The calibration curves were linear over the concentration range $0.05-5.0\;{\mu}g/ml$ for triflusal and $0.2-200.0\;{\mu}g/ml$ for HTB with correlation coefficients greater than 0.999 and with intra-day or inter-day coefficients of variation not exceeding 10.0%. This assay procedure was applied to the study of metabolite pharmacokinetics of triflusal and HTB in rats. It was supposed that triflusal was almost metabolized in vivo because urinary and biliary excreted amounts of triflusal could be ignored as it was lower than 1.2% of the administered dose. According to the gastrointestinal and hepatic biotransformation pathways of triflusal, it was found that triflusal was hydrolyzed by about 5% in intestine and metabolized by about 53% in liver, and that the bioavailability of triflusal after oral administration of triflusal was 0.44, and also that the fraction of total elimination rate of triflusal which formed HTB in liver $(F_{mi},\;%)$ was about 98%. These results showed that triflusal was almost metabolized in liver, and the total elimination of triflusal in the body was dependent to the formation rate of HTB from triflusal in liver.

• Journal of Electrical Engineering and Technology
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• v.12 no.4
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• pp.1449-1455
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• 2017

The vector control technique using low-resolution Hall-effect sensors has been widely used especially in consumer electronics. Due to electrical and/or mechanical unevenness related to binary-type Hall sensors, the calculated or estimated position information has discontinuities so called bumps, which causes the deterioration of vector control performance. In order to obtain a linearly changing position signal from low-precision Hall-effect sensors, this paper proposes a simple bumps in position signal removal algorithm that consists of a first-order observer with low-pass filtering scheme. The proposed algorithm has the feature of no needs for system parameters and additional estimation processes. The validity of the proposed method is verified through simulation and experimental results.

• Journal of Pharmaceutical Investigation
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• v.22 no.4
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• pp.301-306
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• 1992

The influence of phenobarbital (PB) pretreatment (75 mg/kg/day, i.p. for 4 days) on the metabolite kinetics of diltiazem (DTZ) was studied in rats in order to elucidate the effect of esterase induced by PB on the formation of DTZ to desacetyldiltiazem (DAD), DAD was injected via portal vein (3 mg/kg) to the control and PB-pretreated rats, The intrinsic hepatic clearance of DAD was significantly increased by PB pretreatment and the absolute bioavailability of DAD was significantly decreased in the PB-pretreated rats. According to the hepatic biotransformation model of DTZ, the fraction of systemic clearance of DTZ which forms DAD $(G_{mi})$ was different from that of DTZ which furnishes the available DAD to the systemic circulation $(F_{mi})$ in control rats. This result shows that DTZ was suspected of the sequential hepatic first-pass metabolism. On the other hand, PB pretreatment enhanced the $G_{mi}$ value of DTZ by 44%. It may be concluded that the deacetylation of DTZ to DAD in rats is increased by the esterase induced by PB but the transfer rate of DAD immediately formed from DTZ into systemic circulation is not affected by PB due to the 27% decreased absolute bioavailability of DAD resulting from PB pretreatment.

• Journal of information and communication convergence engineering
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• v.5 no.2
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• pp.126-130
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• 2007

This paper proposes a method that automatically extracts characteristics of cracks such as length, thickness and direction, etc., from a concrete surface image with image processing techniques. This paper, first, uses the closing morphologic operation to adjust the effect of light extending over the whole concrete surface image. After applying the high-pass filtering operation to sharpen boundaries of cracks, we classify intensity values of the image into 8 groups and remove intensity values belong to the highest frequency group among them for the removal of background. Then, we binarize the preprocessed image. The auxiliary lines used to measure cracks of concrete surface are removed from the binarized image with position information extracted by the histogram operation. Then, cracks broken by the removal of background are extended to reconstruct an original crack with the $5{\times}5$ masking operation. We remove unnecessary information by applying three types of noise removal operations successively and extracts areas of cracks from the binarized image. At last, the opening morphologic operation is applied to compensate extracted cracks and characteristics of cracks are measured on the compensated ones. Experiments using real images of concrete surface showed that the proposed method extracts cracks well and precisely measures characteristics of cracks.

• Journal of Pharmaceutical Investigation
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• v.34 no.1
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• pp.15-21
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• 2004

The pharmacokinetics of orally administered verapamil (10 mg/kg) was studied in six rabbits after 20 min pretreatment with quercetin ad coadministration of quercetin (2.0 mg/kg, 1 mg/g and 20 mg/kg, respectively). Pretreatment with quercetin significantly (p < 0.01, p < 0.05) increased the plasma concentration of verapamil. However, coadministration of quercetin showed no significantly effect on the pharmacokinetic parameters of verapamil. The elimination rate constant $(K_{el})$ of verapamil pretreated with quercetin (1 mg/kg and 20 mg/kg) was significantly (p < 0.05) reduced compared with control. The area under the plasma concentration-time curve (AUC) and the peak concentration $(C_{max})$ of verapamil pretreated with quercetin (2.0 mg/kg, 10 mg/kg and 20 mg/kg) were increased significantly (p < 0.01, p < 0.05) compared with control. Pretreatment with quercetin (2.0 mg/kg, 10 mg/kg and 20 mg/kg) significantly (p < 0.01, p < 0.05) increased the relative bioavailability of verapamil to 159 - 219%. These results suggest that quercetin alters disposition of verapamil by inhibition of P-glycoprotein efflux pump and its first-pass metabolism. The dosage of verapamil should be adjusted when it is administered chronically with quercetin in a clinical situation.

• Journal of Korea Technical Association of The Pulp and Paper Industry
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• v.39 no.1 s.119
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• pp.8-15
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• 2007

In an effort to develop control strategies for the wet-end of paper machines, dynamic models for retention and formation processes have been developed. The retention process, including headbox total and filler consistencies, white water total and filler consistencies, the basis weight and the ash content of paper, can be modeled from first-principles (mass balances). To include the effect of wet-end chemistry variables, first-pass retention was included as a parameter dependent on operating conditions. In addition, dynamics of formation was simulated by developing an empirical model of formation and coupling with the dynamic models for the retention process. A series of experiments were performed using a pilot paper machine. The experimental results and the model predictions showed relatively good agreement.