• Molecules and Cells
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• v.38 no.5
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• pp.432-440
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• 2015

Human osteosarcoma usually presented a high tendency to metastatic spread and caused poor outcomes, however, the underlying mechanism was still largely unknown. In the present study, using a series of in vitro experiments and an animal model, we investigated the roles of HOX antisense intergenic RNA (HOTAIR) during the proliferation and invasion of osteosarcoma. According with our results, HOTAIR was commonly overexpressed in osteosarcoma, which significantly correlated with advanced tumor stage, highly histological grade and poor prognosis. In vitro and in vivo experiments demonstrated that knockdown of HOTAIR could notably suppress cellular proliferation, inhibit invasion and decrease the secretion of MMP2 and MMP9 in osteosarcoma. Collectively, our results suggested that HOTAIR might be a potent therapeutic target for osteosarcoma.

• Fire Science and Engineering
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• v.21 no.1 s.65
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• pp.19-28
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• 2007

The result of survey on job satisfaction of first-aid staff found that degree of work-related stress of 119 first-aid staff got total average 2.54 point (SD.44) out of 4. The degree of fatigue that first-aid staff feel got 2.09 point (SD.49) out of 4. The degree of job satisfaction of 119 first-aid staff got 2.71 point out of 5. This study suggests increasing of new hire, continuous education through teaching before employment, studying abroad, and so on, expansion and modernization of first-aid equipment, introduction and management of OAT institution for improvement of job satisfaction of first-aid staff.

• Journal of the korean academy of Pediatric Dentistry
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• v.3 no.1
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• pp.19-31
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• 1976

To study the eruption pattern of the mandibular first permanent molar, the author took 263 cases of Oblique Cephalogram from age 3 to 6 years old children and observed the vertical and mesiodistal directional change and tooth axis change. The following results were obtained.; 1. The eruption pattern of the mandibular first permanenl molar was changed at about 60~66 months or calcification stage IX. 2. At the early stage, the path of eruption of the mandibular first permanent molar directed upward and forward and after calcification stage IX it changed to the direction of upward. 3. The height of the alveolar bone of the upper part of the mandibular first permanent molar was almost equal to that of the interseptal bone of the first and second deciduous molar, but the height showed gradual descent afterwards. 4. At the early stage, the distance from the distal end of the mandibular second deciduous molar to the anterior portion of the ascending ramus was 1.2~1.4 times larger than the mesio-distal diameter of the mandibular first permanent molar, but at the later stage it was enlarged 1.7~1.9 times larger than the mesiodistal diameter of the mandibular first permanent molar.

• Journal of Korean Academy of Oral and Maxillofacial Radiology
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• v.25 no.2
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• pp.281-286
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• 1995

Tooth length determination is a crucial step in endodontic treatment. Traditionally, radiographs are used to confirm working length of the root length. This study was performed to evaluate the radiographic distortion(magnification) and calculate correction coefficients for the object-film distance. Ninty-six radiographs were made of eight extracted teeth(two upper first premolars, two lower first premolars, two upper first molars, and two lower first molars) by using the 16 inch long cone paralelling techniques with 1mm interval from 5 to 16mm tooth-film distance. The results were as follows. 1. The least mean radiographic distortion from 5 to 16mm tooth-film distance was 2.42±0.68％(the length of mesiobuccal cusp-mesial root of lower first molars), the greatest distortion was 4.74±1.36％(the length of mesiobuccal cusp-mesiobuccal root of upper first molars). 2. The greatest correction coefficient was 0.986(the mesiobuccal cusp-mesial root of lower first molars, the lowest one was 0.937(the mesiobuccal cusp-mesiobuccal root of upper first molars).

• Restorative Dentistry and Endodontics
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• v.6 no.1
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• pp.63-70
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• 1980

This study was to determine the incidence of pulp stone in each tooth by means of analyzing 375 orthopantomograph taken from 375 patients (252 male), 125 female). The pictures were grouped by age, 20s, 30s, 40s, 50s, and sex. The results were as follows 1. In the group of 20s, male showed the highest incidence in the first molar (40~50%) and the second highest was in the 2nd molar about 35%~50%. In the female group, the first molar and the second molar showed 25%~40%. 2. In the group of 30s, the highest value was found on the first molar and the next was the 2nd molar which appeared 30%~40% in male. In the female, the first molar was 55%~70% and the 2nd molar 30%~50% 3. In the group of 40s, the first molar represented highest value about 45%~60% and the 2nd molar was 40~60% in the male. Female group also showed in the first molar 30%~50% and the second molar 25~30%. 4. In the group of 50s, the highest incidence was 40%~60% on the first molar and next was 35%~50% on the second molar in male, in femalegroup showed 30%~50% on the first molar and 25%~50% on the second molar. 5. The incidence in upper was higher than that of lower. 6. Comparison between right and left showed right was slightly higher than left side.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.9
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• pp.4071-4077
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• 2014

Background: The effects of CYP1A1 gene polymorphisms on the risk of bladder cancer (BC) remain controversial. We carried out a meta-analysis to clarify the role of CYP1A1 gene polymorphisms in BC. Material and Methods: A comprehensive literature search was conducted up to November 20, 2013. Odds ratios (ORs) with 95% confidence intervals (CIs) were used to estimate the strength of the association. Meta-regression, subgroup analysis, sensitivity analysis and publication bias were also performed. Results: Eight studies involving 1,059 BC cases and 1,061 controls were included. The meta-analysis showed that there was no significant association between the two common mutations of CYP1A1 and BC risk. For the I1e462Val A/G polymorphism with GG vs. AA the OR was 1.47 (95 % CI= 0.70-3.07, P =0.308). For the MspI T/C polymorphism, though a slight trend was found this was not statistically nonsignificant (CC vs.TT, OR = 1.24, 95 % CI= 0.98-1.58, P =0.078). Subgroup analyses by ethnicity also found no obvious association between CYP1A1 and BC risk. Conclusion: The present meta-analysis suggests that CYP1A1 polymorphism is not associated with bladder cancer risk.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.2
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• pp.737-742
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• 2012

To evaluate efficacy of microwave ablation in a primary clinical study, sixty patients (44 men, 16 women; mean age 53 years) with 96, 1-8 cm (mean $3.20{\pm}0.17$ cm) liver cancers were treated with 2,450-MHz internally cooled-shaft antenna. Complete ablation (CA) and local tumor progression (LTP) rates as well as complications were determined. CA rates in small (< 3.0 cm), intermediate (3.1-5.0 cm) and large (5.1-8.0 cm) liver cancers were 96.4% (54/56), 92.3% (24/26) and 78.6% (11/14), respectively. During a mean follow-up period of $17.17{\pm}6.52$ months, LTP occurred in five (5.21%) treated cases. There was no significant difference in the CA and LTP rates between the HCC and liver metastasis patient subgroups (P<0.05). Microwave ablation provides a reliable, efficient, and safe technique to perform hepatic tumor ablation.

• Journal of the Korea Convergence Society
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• v.6 no.3
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• pp.1-12
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• 2015

The purpose of this study is to examine the structure of subjective cognition for first aid in persons taking first aid eduction. The perception of first aid styles were classified by using the PC QUANL program. Data were collected from March to July, 2010. As a result of the study, the cognition for first aid in persons taking first aid eduction can be classified into these four types: 'Time-oriented type', 'First responder-oriented type', 'Convergence education-oriented type', 'Lay person using-oriented type'. Therefore, in the field of first aid practice and education this study has provided practical guidelines helpful to nursing intervention and family-centered nursing by considering each character of the types centering on the relationship of lay person, and will be useful as basic data for relevant disciplines in education.

• Convergence Security Journal
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• v.14 no.6_2
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• pp.83-88
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• 2014

First investigation is urgent investigation activities to arrest and to obtain evidence at the beginning of the incident. If the first investigation is wrong, the crime will not be solved or a lot of evidence will be disappeared. Therefore, if the first investigation is wrong, Wasting a lot of manpower and budget, or the other victims are to occur. First investigation is the crime scene centered investigation, victim centered investigation and damaged goods centered investigation. The crime scene centered investigation is the investigation on the discovery of dropped objects, to confirm thd date of offense, on the discovery of witnesses. Victim centered investigation is the investigation of victim's personal information, the living conditions of the family, fellowship and home interior matter. Damaged goods centered investigation is the investigation on the place of crime damaged goods and the movement route of crime damaged goods. In order to reinforce the investigative capacity of police first investigation, It is needed to reinforce the education on the first investigation, to conduct continuously for FTX (field training), to product the manual for first investigation, to build a case analysis system, to develop of forensic techniques and the coordination of national. The police should be giving people faith from the first investigation.

• Journal of the Korea Fashion and Costume Design Association
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• v.16 no.3
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• pp.33-48
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• 2014

Based on the advent and dissemination of new developments concerning information & telecommunications technology, web services have brought new paradigms into society, thus facilitating the birth and evolution of various service industries to society as a whole. This study is aimed at investigating the expansion of the first Birthday party culture and design examples of the first Birthday partywear appearing in social media, through an inquiry into the communication functions inherent in social media. Also, the development of the first Birthday partywear designs for women aged 20 to 30 years was accomplished by categorically analyzing design characteristics in preferred fashion styles uploaded and shared within online childcare communities. First, it can be concluded that due to the bidirectional flow of information between corporations and consumers occurring from the expansion of social media, the entire structure of the market is undergoing great changes. Next, the need for the supply of professionalized the first Birthday partywear can be proved by the influx of party planners and caterers into this new industry. Third, Through a categorical analysis of these 523 photos, elegance style was the most preferred while classic and romantic styles followed. Last of all, 5 pieces of partywear reflecting contemporary consumer lifestyles which focus on 'enjoying one's own life' were created under the concept of 'Romantic chic'. The created designs aim to present a style which follows the predominant trend of elegance, classic and romantic, whilst keeping sensitivity in moderation. In this context, this study has aimed to present fundamental research data in the field of online the first Birthday partywear, through the development of the first Birthday partywear design based on the first Birthday party consumer characteristics gleaned from various forms of social media.