• Journal of Korean Academy of Fundamentals of Nursing
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• v.14 no.3
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• pp.340-350
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• 2007

Purpose: This study was done to construct a quality of life (QOL) model for recipients of a liver transplant. Method: In consideration of the main factors influencing QOL in recipient of liver transplants, a hypothetical model was constructed with 16 paths. A questionnaire was used to collect data from recipients of liver transplants who were being followed at one of 3 university hospitals. For the final analysis, there were 189 completed questionnaires and the hypothetical model was verified through covariance structure using LISREL program. Results: Overall fitness indices of hypothetical model were GFI= .99, AGFI= .97, NNFI= .96 and RMR=.020. After considering modification indices and paths that proved not to be significant and to improve model fitness, the hypothetical model was modified. In the final model, 3 paths from the hypothetical model were excluded. Overall fitness indices of the final model were GFI= .99, AGFI= .98, NNFI= .98 and RMR= .020. Eleven of fifteen paths proved to be significant. QOL was influenced by duration after transplantation, perceived health status, self-esteem, uncertainty, social support, self efficacy and depression and these variables explained 65% of the variance. Conclusion: This study presents a theoretical model for QOL for recipients of a liver transplant. Based on the results of this study and to improve QOL for recipients of a liver transplant, it is suggested that interventions to re-enforce self efficacy and self-help are needed.

• The Journal of Korean Academic Society of Nursing Education
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• v.30 no.3
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• pp.263-279
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• 2024

Purpose: This study was conducted to evaluate the effects of nurse-led interventions on quality of life, medication adherence, anxiety, and depression in kidney transplant recipients. Methods: A systematic literature review was conducted following Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines. Two researchers independently selected the final literature, and the quality assessment was performed using Cochrane's Risk of Bias tool. Additionally, a meta-analysis was conducted using the statistical software RevMan 5.4 to estimate effect sizes. Results: Among the reviewed 2,264 papers, 8 final papers, including 6 from the literature search and 2 from manual searches, were included in the analysis. The total number of participants included in the analysis was 477. Nurse-led interventions were found to be effective in improving quality of life (d=1.05) and reducing anxiety (d=-0.98) and depression (d=-1.25). Due to the heterogeneity of the measurement tools, the effect size for medication adherence could not be calculated. Despite this, nurse-led interventions were shown to improve medication adherence. In the cases of anxiety and depression, longer intervention periods showed a more significant reduction trend. Conclusion: The results of this study suggest that nurse-led interventions positively impact quality of life, medication adherence, anxiety, and depression in kidney transplant recipients. Therefore, it is important to recognize the crucial role of nurses and explore ways to provide continuous nursing interventions for kidney transplant recipients.

• Journal of Korean Critical Care Nursing
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• v.16 no.3
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• pp.73-86
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• 2023

Purpose : This study aimed to identify the factors affecting the quality of life of lung transplant patients. Method : The participants were patients who received lung transplants at a general hospital in City Y. Data were collected through structured questionnaires from June 2023 to August 2023. General characteristics, lung transplantation-related characteristics, quality of life, functional disability, treatment compliance, social support, anxiety, and depression-were measured. For data analysis, hierarchical multiple regression was performed using SPSS/WIN 29.0. Results : In the final model, quality of life was associated with income, self-help group attendance, functional disability, social support, treatment compliance, and anxiety and depression. Together, they explained 61.2% of the total variance in the results. Conclusion : Our findings suggest that improving lung transplant patients' quality of life requires active intervention in stress management to perform treatment instructions well, a social support system that can help them financially, and encouraging and participating in social activities as patients.

• Journal of Environmental Impact Assessment
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• v.31 no.6
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• pp.423-437
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• 2022

Parts of damaged trees are being transplanted in accordance with the Environmental Impact Assessment Manual. Problems such as death or poor growth are constantly being addressed in the process of transplanting trees from the forest they originally inhabited to temporary and final transplant sites. The purpose of this study is to analyze the differences in soil properties in the surrounding forest, the temporary transplant site, and the construction site and to suggest methods for improving the soil to make it suitable for the growth of transplanted trees. For 10 development projects, 2 soil samples were sampled from the surrounding forest, temporary transplant site, and construction site. A total of 60 soil samples were analyzed for physical and chemical properties. Among the physical properties such as coefficient of permeability, available moisture, and hardness, and chemical properties such as acidity, organic matter content, total nitrogen, and available P showed significant differences among groups. The soil of the construction site is harder than the surrounding forest because of construction equipments, the coefficient of permeability is higherthan the surrounding forest because of high sand content, and the available moisture was low. It does not retain the moisture necessary for plants in the soil and drains immediately. It is necessary to implement tillage to improve the physical properties and structure of the soil. In addition, it is necessary to cover the surface with wood chips or fallen leaves after adding mature organic matter to improve the physical and chemical properties of the soil together.

• Korean Journal of Clinical Pharmacy
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• v.18 no.1
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• pp.60-67
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• 2008

This study aimed to compare a microparticle enzyme immunoassay (MEIA) with a liquid chromatography-tandem mass spectrometry (LC/MS/MS) technique for the measurement of tacrolimus concentrations in adult liver transplant recipients, to investigate how the assay choice influenced the population pharmacokinetics of tacrolimus and to identify patient characteristics that affected pharmacokinetic parameters in each assay. Tacrolimus concentrations from 29 liver (n=52 paired-samples) transplant recipients measured by both MEIA and LC/MS/MS were used to evaluate the performance of these methods in the clinical setting. Tacrolimus pharmacokinetics was studied independently using MEIA and LC/MS/MS data in 70 adult patients using a population approach performed with NONMEM. Patient characteristics which influenced pharmacokinetic parameters in each assay were compared. The relation between LC/MS/MS and MEIA measurements was best described by the regression equation MEIA=1.465*LC/MS/MS-1.336 (r=0.91). Multiple linear regression analysis showed significant inverse relationships between assay difference and hematocrit (Hct) (p<0.025) in liver graft recipients. In MEIA, the population estimate of tacrolimus CL/F and apparent volume of distribution (Vd/F) were found to be 10.1 L/h and 226 L, and in LC/MS/MS, 13 L/h and 305 L respectively. Neither patient's age, weight, gender, grafted hepatic weight, albumin concentration, nor markers of liver function influenced tacrolimus CL/F The final model of CL/F was found to be 10.1+(Hct/Hct mean)$^{12.0}$ in MEIA and 13+(1+Hct/578) in LC/MS/MS indicating that CL/F was influenced by hematocrit.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.68 no.4
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• pp.225-235
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• 2023

Critical temperature for grain filling of three Korean japonica rice varieties was analyzed by late transplantation to induce a low temperature during grain filling period in a field study. The grain filling percentage (GFP) and grain dry weight (GDW) showed a sigmoid development for the first and second transplants in 2020 and first to third transplants in 2021. For the third transplant in 2020 and fourth transplant in 2021, the GFP and GDW reached a peak at 42 days after heading (DAH), and then decreased or remained unchanged. In non-linear regression analyses, 95% of the final GFP and GDW appeared at 49 - 62 DAH for the second transplant in 2020 and at 37 - 46 DAH and 30 - 36 DAH for the second and third transplants in 2021, respectively. At these time points, the critical seven-day moving temperature (7dMovT) was 8.4~9.4℃ for the second transplant in 2020 and 9.4~10.9℃ for the second and third transplants in 2021, depending on the grain filling traits and varieties of rice. The lowest 7dMovT was 8.4 - 8.7℃ in the three varieties. The observed lowest 7-day mean temperature (7dMT) accompanying increases in the GFP and GDW was 9.4 - 10.1℃, depending on the varieties in the third transplant of 2020 and fourth transplant of 2021. In the two transplants mentioned above, the highest 7dMT that showed no increase or decrease in grain filling traits was 8.7 - 9.1℃. The critical temperature for grain filling of japonica rice was 8.4 - 8.7℃ based on the 7dMovT and 9.1 - 9.4℃ based on the 7dMT. The previous 7dMT of 10℃ is recommended to determine the marginal harvest time for safe rice cropping since the temperature was the highest among the lowest temperature that accompanied an increase in grain filling traits.

• Journal of the korean academy of Pediatric Dentistry
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• v.24 no.3
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• pp.710-717
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• 1997

Autotransplantation is the transplantation of embeded, impacted, or unerupted tooth, into extraction socket or surgically prepared socket in the same individual. Clinically, successful autotransplantation must show radiolucent space(periodontal ligament space) between transplanted tooth and supporting bone, lamina dura, no root resorption, no ankylosis, no inflammatory change, and physiologic tooth mobility. It is important that procedure is atraumatic, and the instruments should not contact the root surface during procedure. We performed autotransplantation of impacted mandibular canine that transversely located beneath the apices of the mandibular incisors with uncompletely developed apex. In radiographs and clinical evaluation, this transplant showed successful clinical finding except irregularity of mesial root surface after 14 months. It is conclued that transplantation of canine with $\frac{1}{2}{\sim}\frac{3}{4}$ root development provides a good chance of pulp survival, limited risk of root resorption and ensures sufficient final length, and is thus recommended.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.19 no.1
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• pp.44-53
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• 2016

Purpose: Parenteral nutrition (PN) not only provides nutritional support but also plays a crucial role in the treatment of children with intestinal failure. The aim of this study was to evaluate the clinical significance and clinical outcomes of long-term PN. Methods: Retrospective cohort study was conducted using the medical records of patients treated at Seoul National University Children's Hospital. This study included 19 patients who received PN for over six months. Most patients received home PN. Results: The indications for PN included short bowel syndrome, chronic intestinal pseudo-obstruction, and intractable diarrhea of infancy. The median age of PN initiation was 1.3 years, and the median treatment duration was 2.9 years. Two patients were weaned from PN; 14 continued to receive PN with enteral feedings; and 3 patients died. The overall survival rates at 2 and 5 years were 93.3% and 84.0%, respectively. The incidence of catheter-related bloodstream infections was 2.7/1,000 catheter-days and was associated with younger age at PN initiation and lower initial height Z-score. Six patients developed catheter-related central vein thrombosis, with an incidence of 0.25/1,000 catheter-days. Eleven patients experienced PN-associated liver disease (PNALD), and one patient underwent multi-visceral transplant. The patients with PNALD exhibited lower final heights and body weight Z-scores. All patients experienced micronutrient deficiencies transiently while receiving PN. Conclusion: PN is an important and safe treatment for pediatric intestinal failure. PNALD was linked to final anthropometric poor outcomes. Micronutrient deficiencies were common. Anthropometric measurements and micronutrient levels must be monitored for successful PN completion.

• The Journal of the Korea Contents Association
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• v.19 no.2
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• pp.619-628
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• 2019

This study is an explanatory research conducted to analyze the influencing factors of treatment adherence in kidney transplant recipients. The subjects were 132 renal transplant recipients who visited the outpatient department in a university hospital. Data were collected from July 17, 2017, to August 22, 2017, and analyzed using SPSS WIN 24.0. Frequency, percentage, mean and standard deviation, variance analysis, correlation, and regression analysis were performed. The results of the study showed that there was a significant difference in the treatment adherence based on the age, religion, and the time passed since kidney transplantation. The study also found that the treatment adherence had significant positive correlations with social support (r=.54, p<.001), family support (r=.43, p<.001), health provider's support (r=.57, p<.001), and self-care knowledge (r=.21, p=.015). The factors influencing the treatment adherence were health provider's support, the time passed since kidney transplantation, spouse, and religion. The final explanatory power of the model was 41.9%. In conclusion, intervention strategies should be introduced to promote the support of healthcare providers in order to improve the adherence of the kidney transplantation patients.

• Archives of Reconstructive Microsurgery
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• v.17 no.2
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• pp.101-107
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• 2008

Purpose: Free flaps from the great toe are an established method for reconstruction of absent or partially amputated thumbs. However, options differ as to which technique represents the ideal solution for each level of amputation. Various methods of distal thumb reconstruction have been proposed. We prefer to transplant the entire great toe nail complex with the almost all of the pulp rather than a portion of the nail. This paper reflects our experience in using the great toe mini wrap-around flap for distal thumb reconstruction. Materials and Methods: In the period from October of 2005 to July of 2007, 9 patients were treated for traumatic thumb defects localized at the distal phalanx of the thumb. The patients included seven men and two women. The mean age was 44 years (range, 21~60) and the dominant right hand was involved in seven of nine patients. Results: The transferred flaps have survived completely in all cases. The mean range of motion in the interphalangeal joints was 51o, with 73% of the normal uninjured opposite hands. The two-point discrimination was 10.5 mm (range, 5~13 mm). In Semmes-Weinstein monofilament test, the sensibility was 4.31 in 4 cases, 3.61 in 3 cases and 2.83 in 2 cases. The pinch power was 64% (range, 55~95%) of the opposite hand. All patients were satisfied with the appearance of the reconstructed thumb and felt comfortable at final follow-up. Conclusion: We have successfully reconstructed 9 cases of traumatic distal thumb defects using the mini wrap-around free flap. The mini wrap-around free flap in great toe is an excellent alternative method for distal thumb reconstruction in selected patients.