• Journal of Periodontal and Implant Science
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• 제51권6호
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• pp.374-385
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• 2021

Purpose: The aim of this study was to evaluate the effects of locally delivered 1% alendronate (ALN) gel used as an adjunct to non-invasive periodontal therapy. Methods: Ligature-induced periodontitis was performed in 96 rats. The ligature was tied in the cervical area of the mandibular left first molar. The animals were randomly divided into 4 groups: 1) NT, no treatment; 2) SRP, scaling and root planning; 3) SRP/PLA, SRP followed by filling the periodontal pocket with placebo gel (PLA); and 4) SRP/ALN, SRP followed by filling the periodontal pockets with 1% ALN gel. Histomorphometric (percentage of bone in the furcation region [PBF]) and immunohistochemical (receptor activator of nuclear factor-κB ligand, osteoprotegerin, and tartrate-resistant acid phosphatase) analyses were performed. Data were statistically analyzed, with the threshold of statistical significance set at P≤0.05. Results: The SRP, SRP/PLA, and SRP/ALN groups presented a higher PBF than the NT group (P≤0.01) at 7, 15, and 30 days. The SRP/ALN group presented a higher PBF than the SRP/PLA group in all experimental periods, as well as a higher PBF than the SRP group at 15 and 30 days. No differences were observed in the immunohistochemical analyses (P>0.05 for all). Conclusions: Locally delivered 1% ALN gel used as an adjunct to SRP enhanced bone regeneration in the furcation region in a rat model of experimental periodontitis.

• Journal of Cardiovascular Imaging
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• 제26권4호
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• pp.217-225
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• 2018

BACKGROUND: In patients with acute heart failure (AHF), diastolic dysfunction, especially pseudonormal (PN) or restrictive filling pattern (RFP) of left ventricle (LV), is considered to be implicated in a poor prognosis. However, prognostic significance of diastolic dysfunction in patients with ischemic heart disease (IHD) has been rarely investigated in Korea. METHODS: We enrolled 138 patients with IHD presenting as AHF and sinus rhythm during echocardiographic study. Diastolic dysfunction of LV was graded as ${\geq}2$ (group 1) or 1 (group 2) according to usual algorithm using E/A ratio and deceleration time of mitral inflow, E'/A' ratio of tissue Doppler echocardiography and left atrial size. RESULTS: Patients in group 1 showed higher 2-year mortality rate ($36.2%{\pm}6.7%$) than those in group 2 ($13.6%{\pm}4.5%$; p = 0.008). Two-year mortality rate of patient with LV ejection fraction (LVEF) < 40% ($26.8%{\pm}6.0%$) was not different from those with LVEF 40%-49% ($28.0%{\pm}8.0%$) or ${\geq}50%$ ($13.7%{\pm}7.4%$; p = 0.442). On univariate analysis, PN or RFP of LV, higher stage of chronic kidney disease (CKD) and higher New York Heart Association (NYHA) functional class were poor prognostic factors, but LVEF or older age ${\geq}75$ years did not predict 2-year mortality. On multivariate analysis, PN or RFP of LV (hazard ratio [HR], 2.52; 95% confidence interval [CI], 1.09-5.84; p = 0.031), higher stage of CKD (HR, 1.57; 95% CI, 1.14-2.17; p = 0.006) and higher NYHA functional class (HR, 1.81; 95% CI, 1.11-2.94; p = 0.017) were still significant prognostic factors for 2-year mortality. CONCLUSIONS: PN or RFP of LV was a more useful prognostic factor for long-term mortality than LVEF in patients with IHD presenting as AHF.

• 한국작물학회:학술대회논문집
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• 한국작물학회 2017년도 9th Asian Crop Science Association conference
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• pp.353-353
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• 2017

Rice yield of South Korea in 2015 was the highest of the last 30 years. It is important issue to establish food policy whether the historically highest yield in 2015 can be continued or just one-off event. Therefore, it is necessary to understand whether such a high yield as 2015 will be reoccurred. The aim of this study was to find out what climatic factor affect rice yield and how often these climatic factor could occur. For this study, the yield monitoring data from National Institute of Crop Science, Rural Development Administration and the meteorological data provided by Korea Meteorological Administration are used to identify the weather conditions could cause high yield, and how often these conditions occurred in the past. Our results indicated that such as high yield as 2015 could occur only when the mean sunshine hours of July and the mean sunshine hours from the end of August to early September was more than 5.1 hours and 6 hours, respectively. Mean sunshine hour of July may be related to grain number. The mean sunshine hour from the end of August to early September was presumed to relate to grain filling ratio. The relationship between monthly mean temperature and yield or yield component was not clear in this study. In this study, any cycle of high weather condition was not found. Therefore, the probability of high yield weather condition was expressed by frequency. The frequency of the sunshine hour, could make high yield, were 8/35 (23%) over the past 35 years. And the frequency of two years consecutive sunshine hour condition, which could cause high yield, was 1/35 (2.9%). The frequency of recurrence of sunshine hour making high yield within the next 5 years or 10 years after high yield weather condition were 4/35 (11.4%). After all, the high yield as much as yield of 2015 could not be one-off event. But it was not also consecutive event.

• 대한방사선기술학회지:방사선기술과학
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• 제45권6호
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• pp.523-529
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• 2022

Gamma spectroscopy analysis is widely used for radioactivity analysis, and various factors are required for radioactivity calculations. Among the factors, K3 for each sample significantly influences the results. The previous methods of correcting the self-absorption effect include a computational simulation method and a method that requires making a CRM(certified reference material) identical to the sample medium. However, the above methods have limitations when used in small institutions because they require specialized program utilization skills or high manufacturing costs and large facilities. The aim of this study is to develop a method that can be easily and rapidly applied to radioactivity analysis. After filling the beaker with water, we placed the radiation source in a uniform position and used the measured value as the benchmark. Next, a correction factor was derived based on the difference in the radiation source count of the benchmark and the identically measured sample. For the radiation source, Eu-152, which emits a broad range of energy within the measurement range of gamma rays, and Cs-134 and Cs-137, which are indicator nuclides in environmental radiation analysis, were used. The sample was selected within the density range of 0.26-2.11 g/cm³, and the correction factor was derived by calculating the count difference of each sample compared to the reference value of water. This study presents a faster and more convenient method than the existing research methods for determining the self-absorption effect correction, which has become increasingly necessary.

• 한국콘텐츠학회논문지
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• 제8권12호
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• pp.433-440
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• 2008

본 연구의 목적은 청소년의 여가활동제약이 여가만족에 미치는 영향을 규명하는 것이다. 이를 위해 2008년 K도 교육청 산하 C시 인문계 고등학교 재학생을 모집단으로 선정하여 무선표집법으로 300명을 표집하였다. 최종 자료분석에 사용된 사례수는 259명이었고 측정도구는 설문지를 이용하였다. 특히 설문지의 신뢰도 분석결과 Cronbach'${\alpha}$ 값이 여가제약은 .952 여가만족도는 .941로 나타났다. 자료분석은 SPSS 12.0 통계프로그램을 이용하여 빈도분석과 회귀분석을 실시하였다. 이와 같은 연구방법을 통해 얻은 결론은 다음과 같다. 첫째, 여가제약은 심리적 만족에 영향을 미치는 것으로 내재적 제약은 심리적 만족에 정적 영향을 미치는 반면 대인적 제약은 부적영향을 미친다. 둘째, 여가제약은 휴식적 만족에 영향을 미치는 것으로 내재적 제약은 휴식적 만족에 정적 영향을 미친다.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2009년도 하계학술대회 논문집
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• pp.210-211
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• 2009

In this study, we propose characteristics improvement methods according to via hole plating method for FBAR Duplexer with US PCS($T_x$:1850MHz~1910MHz, $R_x$:1930MHz~1990MHz) bandwidth which is used for wireless systems. Also, we designed and fabricated 3.8*3.8*1.8mm size microminiature FBAR Duplexer based on this proposal. First of all, in this study, we fabricated pentagon shape resonators by different size to make filter combination, and their quality factor(Q) are 687 with 6.6% of $k_{eff}^2$. Using this resonators, designed 3*2Type $T_x$ filter and 3*4Type $R_x$ filter. The transmission line, which works as phase shifter, is designed with $210{\mu}m$ in width and 18mm in length Stripline type. Inductor, which is used for matching component, is designed with width of $75{\mu}m$, a technically achievable minimum width. And adopted plating method of filling via hole with conductive epoxy for improved grounding and thermal conductivity. Using these configuration with all of the matching component values, we found Duplexer characteristics of -1.57dB ~ -1.73dB in insertion loss, -56dB in attenuation at 1850MHz~1910MHz of $T_x$ band. Also, found -2.71 dB ~ -3.23dB in insertion loss, -58dB in attenuation at 1930MHz~1990MHz of $R_x$ band.

• 대한치과의사협회지
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• 제54권5호
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• pp.365-373
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• 2016

Purpose: Cemental tear is a specific type of root surface fracture characterized by a complete separation of a cemental fragment along the cementodentinal junction or a partial split within the cementum along an incremental line. It is suggested to be a factor for periodontal or periapical tissue destruction. The aim of this study is to present a diagnosis and treatment of cemental tear associated with periapical lesion with root canal treatment and regenerative periodontal surgery. Treatments: A 60-year-old male who had a history of sports trauma on the mandibular right central incisor about 10 years ago presented with apical cemental tear. Clinical examination showed a slightly dark yellowish discoloration and sinus tract that was located on the apical labial mucosa. The mobility and percussion were also assessed on the diseased tooth and recorded as $Miller^{\circ}{\phi}s$ Class II and tenderness to percussion. The probing depth was within the normal limit (<3 mm). Radiographic examination revealed a radiolucent lesion at the apical area and extended to distal aspect of the tooth along the fragment of cemental tear. After root canal treatment, periapical surgery was performed. The bony defect was exposed and then the detached root fragment was removed. Apical root resection and retrograde filling with Mineral Trioxide Aggregate (MTA) were accomplished and the bony defect was filled with deproteinized bovine bone mineral (DBBM) and covered with biodegradable collagen membrane. Results: After 9-month follow-up, healing of the mandibular right central incisor was uneventful and no swelling, purulence or pain was revealed in the associated area. Probing pocket depth was favorably stable, and the tooth mobility was decreased to the Miller's Class I. Conclusions: Apical cemental tear associated periapical lesion could be successfully treated with removal of the detached cementum in combination with apical surgery and GTR procedure.

• 한국환경과학회지
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• 제24권2호
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• pp.253-260
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• 2015

Enlargement of street tree planting area is the proper and effective solution to reduce carbon dioxide. This solution bases on the ability of carbon storage and uptake by tree metabolism. However, the circumstance of road side has fatal disadvantages in tree metabolism such as growth and maturity because cutting and filling of roadsides cause unnatural soil composition. In this point, early rootage of street tree is the main factor of reducing carbon dioxide. This study aimed to find a appropriate transplantation planting method for sound and rapid rootage of street tree. For the study, Korean Mountain Ash(Sorbus alnifolia) were used for experimental groups. The groups were categorized by three groups such as trees produced on container with mulching treatment, trees produced in outdoor with mulching treatment, trees produced on container with weeding treatment. Each group consisted 10 trees with same size and transplanted in experimental site. Five months after transplanting, each group was estimated the biomass and carbon storage through a direct harvesting method. According to results of the study, the carbon storage of trees produced on container with mulching treatment is 42% more than trees produced in outdoor with mulching treatment. And the carbon storage of trees produced on container with mulching treatment is 19.5% more than trees produced on container with weeding treatment. These results may imply that transplantation of container produced tree with mulching treatment is the most rapid rootage among other groups. The weeding treatment is more effective than mulching treatment for rapid rootage of street trees.

• 한국자동차공학회논문집
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• 제20권4호
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• pp.46-51
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• 2012

Injection pressure, an important factor in filling process, should be minimized to enhance injection molding quality. Injection pressure can be controlled by valve gate open timing. In this work, we decided the valve gate open timing to minimize the injection pressure. To solve this design problem, we integrated MAPS-3D (Mold Analysis and Plastic Solution-3Dimension), a commercial injection molding CAE tool, to PIAnO (Process Integration, Automation and Optimization), a commercial PIDO (Process Integration, and Design Optimization) tool using the file parsing method. In order to reduce computational cost, we performed an approximate optimization using meta-models that replaced expensive computer simulations. At first, we carried out DOE (Design of Experiments) using OLHD (Optimal Latin Hypercube Design) available in PIAnO. Then, we built Kriging models using the simulation results at the sampling points. Finally, we used micro GA (Genetic Algorithm) available in PIAnO. Using the proposed design approach, the injection pressure has been reduced by 13.7% compared to the initial one. This design result clearly shows the validity of the proposed design approach.

• Journal of Computational Design and Engineering
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• 제3권1호
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• pp.37-52
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• 2016

To injection mould polymers, designing mould is a key task involving several critical decisions with direct implications to yield quality, productivity and frugality. One prominent decision among them is specifying sprue-bush conduit expansion as it significantly influences overall injection moulding; abstruseness anguish in its design criteria deceives direct determination. Intuitively designers decide it wisely and then exasperate by optimising or manipulating processing parameters. To overwhelm that anomaly this research aims at proposing an ideal design criteria holistically for all polymeric materials also tend as a functional assessment metric towards perfection i.e., criteria to specify sprue conduit size before mould development. Accordingly, a priori analytical criterion was deduced quantitatively as expansion ratio from ubiquitous empirical relationships specifically a.k.a an exclusive expansion angle imperatively configured for injectant properties. Its computational intelligence advantage was leveraged to augment functionality of perfectly injecting into an impression gap, while synchronising both injector capacity and desired moulding features. For comprehensiveness, it was continuously sensitised over infinite scale as an explicit factor dependent on in-situ spatio-temporal injectant state perplexity with discrete slope and altitude for each polymeric character. In which congregant ranges of apparent viscosity and shear thinning index were conceived to characteristically assort most thermoplastics. Thereon results accorded aggressive conduit expansion widening for viscous incrust, while a very aggressive narrowing for shear thinning encrust; among them apparent viscosity had relative dominance. This important rationale would certainly form a priori design basis as well diagnose filling issues causing several defects. Like this the proposed generic design criteria, being simple would immensely benefit mould designers besides serve as an inexpensive preventive cliché to moulders. Its adaption ease to practice manifests a hope of injection moulding extremely alluring polymers. Therefore, we concluded that appreciating injectant's polymeric character to design exclusive sprue bush offers a definite a priori advantage.