• Title/Summary/Keyword: FePc

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The Relationship between Indoor Air Pollutants and Pulmonary Function in Asthmatic Children with Mold Sensitization (곰팡이에 감작된 소아 천식 환자 가정내 환경유해물질 농도와 폐기능의 상관관계)

  • Yoon, Wonsuck;Lim, Jaehoon;Park, Sang Hyun;Lee, Mingyu;Yoo, Young
    • Journal of Environmental Health Sciences
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    • v.46 no.6
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    • pp.685-693
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    • 2020
  • Objectives: Recent data indicate that sensitization to mold contributes to the severity and persistence of asthma. The aim of this study was to investigate relationships between indoor mold concentrations and pulmonary function parameters in asthmatic children with mold sensitization. Methods: Asthmatic subjects who had a positive result in skin-prick testing to more than one mold allergen, such as Alternaria, Aspergillus, or Penicillium, were enrolled. Their pulmonary function and methacholine challenge test results were collected. Measurements of blood eosinophil, serum IgE, and fractional exhaled nitric oxide (FeNO) were taken. Indoor levels of VOC, CO2, PM10 and PM2.5 in each subject's house were measured. We counted mold and bacteria colonies from the subjects' house air samples. Results: The mean levels of FEV1, FVC, FEV1/FVC, and FEF25-75 were 82.8±19.7, 87.3±17.9, 85.8±8.3, and 82.3±28.9%, respectively. The mean FeNO level was 19.8±11.2 ppb and the geometric mean (range of one SD) of methacholine PC20 was 3.99 mg/mL (0.67-23.74 mg/mL). The average indoor air pollutant levels were below the recommended levels set by the Ministry of Environment for multiplex buildings. Indoor mold levels showed a significant inverse correlation with methacholine PC20, but not with the baseline pulmonary function parameters. Conclusion: Indoor mold concentrations are a risk factor for increased bronchial hyperresponsiveness among asthmatic children with mold sensitization. Targeted environmental intervention should be considered for selected asthmatic children with mold sensitization for avoiding severe airway hyperresponsiveness.

Solvent Extraction of Light (Pr, Nd) and Medium (Tb, Dy) Rare Earth Elements with PC88A of Rare Earth Chloride Solution from Waste Permanent Magnet (폐 영구자석으로부터 회수한 염화희토류용액에서 PC88A를 이용한 경희토류(Pr, Nd)/중희토류(Tb, Dy) 용매추출)

  • Jeon, Su-Byung;Son, InJoon;Lim, Byung-Chul;Kim, Jeong-Mo;Kim, Yeon-Jin;Ha, Tae-Gyu;Yoon, Ho-Sung;Kim, Chul-Joo;Chung, Kyeong-Woo
    • Resources Recycling
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    • v.27 no.3
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    • pp.8-15
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    • 2018
  • Solvent extraction behavior of light rare earth elements (Pr, Nd) and medium rare erath elements (Tb, Dy) in the HCl-PC88A-kerosene extraction system was investigated in order to separate high-purity light rare earths (Pr, Nd) and medium rare earths (Tb, Dy) in the mixed rare earth chloride solution. In the batch test step, it was confirmed that the separation efficiency was good when the extractant concentration (PC88A) was 0.5 M, the equilibrium pH after extraction was 0.8 to 1.0 (initial pH 1.3 of the feed), the concentrations of hydrochloric acid in scrubbing solution was set as 0.1 M, the concentrations of hydrochloric acid in stripping solution was set as 2.0 M or more. Based on the experimental data obtained from the batch test, the mixer-settler was composed as follows; 4 stages of extraction, 8 stages of scrubbing, 4 stages of stripping, and 3 stages of pickling organic solution. The Mixer-settler was operated for 180 hours, and the operating conditions were continuously adjusted to obtain the high-purity light/medium rare earths. Finally, the purity of light (Pr, Nd) and medium rare earth elements (Tb, Dy) was reached as 3 N class.

Screening of Anti-thrombotic Activity of Herbal Extracts in Ferric Chloride-induced Thrombosis Model (경동맥 혈전 유발 동물모델을 이용한 한약재 추출물의 효능 검색)

  • Park, In Sil;Lee, Ki Mo;Lee, In Sun;Han, Jae Il;Jeon, Won Kyung
    • The Korea Journal of Herbology
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    • v.28 no.5
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    • pp.33-38
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    • 2013
  • Objectives : The aim of this study was to examine anti-thrombotic effect of traditional herbal extracts in a rat model of ferric chloride ($FeCl_3$)-induced carotid arterial thrombosis. Methods : Thirty minutes prior to a 35% $FeCl_3$ application, Sprague Dawley(SD) rats were injected with the 10 types of traditional herbal extracts (100mg/kg, intraperitoneal injection), respectively. The effect of these herbal extracts was examined for time to occlusion(TTO) using the Laser doppler flow meter and measured for thrombus weight (TW) in $FeCl_3$-induced thrombosis model. Results : In the TTO, Salvia miltiorrhiza (Sm, $2.30{\pm}0.28$ min, p<0.001) and Santalum album (Sa, $2.19{\pm}0.19$ min, p<0.001) showed significantly delayed TTO more than twice compared with Saline-treated group. Cnidium officinale (Co), Psoralea corylifolia (Pc), Scutellatia baicalensis (Sba), Panax notoginseng (Pn), Angelica tenuissima (At), Scrophularia buergeriana (Sbu), Rhus verniciflua (Rv) and Picrasma quassioides (Pq), except for Rhus verniciflua (Rv) also meaningfully impeded TTO more than one fold. In addition, Salvia miltiorrhiza, Santalum album, Cnidium officinale, Psoralea corylifolia and Scutellatia baicalensis significantly reduced TW more than 10% compared with Saline-treated group. Especially, Salvia miltiorrhiza and Santalum album showed the most excellent anti-thrombotic effect among the 10 herbal extracts tested on the restoration of altered TTO and TW. Conclusions : These results suggest that Sm and Sa extracts have outstanding anti-thrombotic effect in $FeCl_3$-induced thrombosis model and is potentially useful as herbal medicines for the treatment and prevention of thrombosis.

Finite element analysis of CFRP laminate repairs on damaged end regions of prestressed concrete bridge girders

  • Shaw, Ian D.;Andrawes, Bassem
    • Advances in Computational Design
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    • v.2 no.2
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    • pp.147-168
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    • 2017
  • Over the past couple decades, externally bonded fiber reinforced polymer (FRP) composites have emerged as a repair and strengthening material for many concrete infrastructure applications. This paper presents an analytical investigation of the use of carbon FRP (CFRP) for a specific problem that occurs in concrete bridge girders wherein the girder ends are damaged by excessive exposure to deicing salts and numerous freezing/thawing cycles. A 3D finite element (FE) model of a full scale prestressed concrete (PC) I-girder is used to investigate the effect of damage to the cover concrete and stirrups in the end region of the girder. Parametric studies are performed using externally bonded CFRP shear laminates to determine the most effective repair schemes for the damaged end region under a short shear span-to-depth ratio. Experimental results on shear pull off tests of CFRP laminates that have undergone accelerated aging are used to calibrate a bond stress-slip model for the interface between the FRP and concrete substrate and approximate the reduced bond stress-slip properties associated with exposure to the environment that causes this type of end region damage. The results of these analyses indicate that this particular application of this material can be effective in recovering the original strength of PC bridge girders with damaged end regions, even after environmental aging.

An Study on Heat Transfer Analysis to Concrete PC Pannel Lining under Tunnel Fire Scenario (터널 화재시나리오에 따른 콘크리트 PC패널 라이닝의 전열특성에 관한 해석적 연구)

  • Kim, Hyung-Jun;Kim, Heung-Youl;Park, Kyung-Hoon;Shin, Hyun-Jun
    • Proceedings of the Korea Institute of Fire Science and Engineering Conference
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    • 2009.04a
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    • pp.487-492
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    • 2009
  • This study was performed FE numerical analysis under 120-minute fire conditions, using the ABAQUS, a wide use software, on the basis of the test results by concrete tunnel lining fire strengths (ISO, RWS, and MHC). The concrete material test was to secure the material properties of concrete linings, which were numerical analysis input conditions. And then built the material properties, such as specific heat, heat transfer rate, heat expansion rate, density, elasticity coefficient and compression strength under high temperature conditions, as database at 20 $^{\circ}C$ to 800 $^{\circ}C$, applying them to analysis as input values. As a result, the tunnel linings under RWS fire conditions saw fire temperature rose to maximum 1119 $^{\circ}C$at the location of 5 mm above a thermal surface, and saw surface temperature amount to 1214 $^{\circ}C$ in the middle part.

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An Experimental Study for the Development of Soil Injection Materials using Vietnam's Circulating Resources (베트남 순환자원을 활용한 지반주입재 개발을 위한 실험적 연구)

  • Young-Won, Lee;Kwang-Wu, Lee;Se-Gwan, Seo;Wan-Kyu, Yoo;Jae-Hyun, Park
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.10 no.4
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    • pp.457-464
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    • 2022
  • In this study, XRF, Loss on ignition, SEM, and PSA analysis were performed on four types of fly ash in Vietnam and compared with fly ash in Korea. As a result, PC boiler fly ash in Vietnam has a similar chemical composition to that of PC boiler fly ash in Korea, where the content of SiO2, Al2O3, and Fe2O3 accounts for about 70%. In addition, the result showed that blast furnace slags in Vietnam and Korea have similar quality criteria and performance. A binder material mixing test using four types of fly ash supplied from Vietnam was conducted, and the compressive strength ranged from 7.60 to 13.25 MPa after 28 days of curing. Vinh Tan fly ash showing the highest compressive strength was selected as the soil injection material for the chemical grouting method. For the formulation of the chemical grouting method, sodium silicate No.3 and silica-sol were used as liquid-A. As a result of measuring the gel time and the compressive strength of the homogel, they showed good performance satisfying the quality criteria applied in Korean construction fields. Therefore, Vinh Tan fly ash can be used as a soil injection material for the chemical grouting method.

EVOLUTIONARY STATUS AND INTERNAL STRUCTURE OF μ CASSIOPEIAE

  • BACH, KIEHUNN
    • Journal of The Korean Astronomical Society
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    • v.48 no.3
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    • pp.165-175
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    • 2015
  • We investigate physical properties of the nearby (∼ 7.5 pc) astrometric binary μ Cas in the context of standard evolutionary theory. Based on the spectroscopically determined relative abundances ([α/Fe] ≳ +0.4 dex, [Fe/H] ∼ −0.7 dex), all physical inputs such as opacities and equation of state are consistently generated. By combining recent spectroscopic analyses with the astrometric observations from the HIPPARCOS parallaxes and the CHARA array, the evolutionary model grids have been constructed. Through the statistical evaluation of the χ2-minimization among alternative models, we find a reliable evolutionary solution (MA, MB, tage) = (0.74 M, 0.19 M, 11 Gyr) which excellently satisfies observational constraints. In particular, we find that the helium abundance of μ Cas is comparable with the primordial helium contents (Yp ∼ 0.245). On the basis of the well-defined stellar parameters of the primary star, the internal structure and the p-mode frequencies have been estimated. From our seismic computation, μ Cas is expected to have a first order spacing ∆ν ∼ 169 μHz. The ultimate goal of this study is to describe physical processes inside a low-mass star through a complete modelling from the spectroscopic observation to the evolutionary computation.

FE Analysis of The Forming Process of The High Precision Rectangular Battery Case used in Cellular Phone and IMT-2000 (Cellular Phone 및 IMT-2000용 초정밀 사각 밧데리 케이스 성형공정 해석)

  • Kim, H.J.;Ku, T.W.;Kang, B.S.
    • Proceedings of the KSME Conference
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    • 2000.11a
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    • pp.778-782
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    • 2000
  • Deep drawing and ironing are the major process used today in manufacturing of battery case used in cellular phone and IMT-2000 from aluminum. The same technology is utilized in manufacturing of steel or aluminum rectangular cans for components of medical instrument, portable PC, walkman and so on. Most of these processes require multi-stage ironing following the deep drawing and redrawing processes. The practical aspects of this technology are well known and gained through extensive experiment and production know-how. However, the fundamental aspects of theses processes are relatively less known. Thus, it is expected that process simulations using FEM techniques would provide additional detailed information that could be utilized to improve the process condition. This paper illustrates the application of process modeling to deep drawing and redrawing operations with the cellular phone and IMT-2000. A commercially avaliable finite element code LS-DYNA3D was used to simulate deep drawing and redrawing operations.

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Nonvolatile Ferroelectric P(VDF-TrFE) Memory Transistors Based on Inkjet-Printed Organic Semiconductor

  • Jung, Soon-Won;Na, Bock Soon;Baeg, Kang-Jun;Kim, Minseok;Yoon, Sung-Min;Kim, Juhwan;Kim, Dong-Yu;You, In-Kyu
    • ETRI Journal
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    • v.35 no.4
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    • pp.734-737
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    • 2013
  • Nonvolatile ferroelectric poly(vinylidene fluoride-co-trifluoroethylene) memory based on an organic thin-film transistor with inkjet-printed dodecyl-substituted thienylenevinylene-thiophene copolymer (PC12TV12T) as the active layer is developed. The memory window is 4.5 V with a gate voltage sweep of -12.5 V to 12.5 V. The field effect mobility, on/off ratio, and gate leakage current are 0.1 $cm^2/Vs$, $10^5$, and $10^{-10}$ A, respectively. Although the retention behaviors should be improved and optimized, the obtained characteristics are very promising for future flexible electronics.

Effect of Feedstuffs on Mineral Composition, Antioxidant Capacity, and Protection of Neuronal PC-12 Cells of Deer Antlers (녹용의 무기질 조성, 항산화능 및 PC-12 신경 세포 보호능에 대한 급여 사료의 영향)

  • Cho, Chi-Heung;Lee, Bong-Han;Kim, Hae-Yeong;Kim, Young-Chae;Kim, Dae-Ok
    • KSBB Journal
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    • v.27 no.4
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    • pp.243-250
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    • 2012
  • The ash content, mineral composition, total phenolics, antioxidant capacity, and neuroprotective effect of the antlers of deer fed with herb-incorporated feedstuff (HFS) or normal feedstuff (NFS) were comparatively evaluated. The contents of ash and mineral of the antler of deer fed with HFS were significantly lower than its counterpart. The ash and mineral contents of deer antlers decreased generally from the upper section toward the tip section. The ratios of Ca/ash, Ca/P, and Ca/Fe of antler of deer fed with HFS were lower than those of antler of deer fed with NFS. Antlers of deer fed with HFS had higher total phenolics, nitrite scavenging capacity, and antioxidant capacity than those of deer fed with NFS. Antlers of deer fed with HFS or NFS showed in vitro neuronal protection of PC-12 cells against oxidative stress in a dose-dependent manner, where antler of deer fed with HFS generally had higher cellular viability than NFS. These results above suggest that the incorporation of the medicinal herbal complex into feedstuff may improve the biological effects of deer antlers.