• 제목/요약/키워드: Fatal syndrome

검색결과 115건 처리시간 0.032초

분선충, Isospora 및 인형세포거대바이러스에 감염된 흡수불량 증후군 1례 (A case of fatal malabsorption syndrome caused by strongyloidiasis complicated with isosporiasis and human cytomegalovirus infection)

  • 윤동헌;양승지
    • Parasites, Hosts and Diseases
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    • 제30권1호
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    • pp.53-58
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    • 1992
  • 환자는 54세 광부로 1991년 1월 낙반사고로 인해 가벼운 골반 골절상을 받았었고, 골절상은 완치되었으나 설사가 지속하고 체중이 심하게 감소하였다. 발병 약 9 개월만에 시행한 대변검사 및 조직 검사에서 분선충중(strongyloidiasis), 포자충중(isosporiasis) 및 인형 세포거대바이러스(heman cytomegalovirus)에 감염된 사실이 확인되었다. Albendazole로 치료하였으나 약 2개월 후 근로복지공사 장성병원에서 난치 상환 하에 퇴원하였으며, 퇴원 1주 후 사망하였다.

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Acute tubular necrosis as a part of vancomycin induced drug rash with eosinophilia and syste­mic symptoms syndrome with coincident post­infectious glomerulonephritis

  • Kim, Kyung Min;Sung, Kyoung;Yang, Hea Koung;Kim, Seong Heon;Kim, Hye Young;Ban, Gil Ho;Park, Su Eun;Lee, Hyoung Doo;Kim, Su Young
    • Clinical and Experimental Pediatrics
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    • 제59권3호
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    • pp.145-148
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    • 2016
  • Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is a rare and potentially fatal condition characterized by skin rash, fever, eosinophilia, and multiorgan involvement. Various drugs may be associated with this syndrome including carbamazepine, allopurinol, and sulfasalazine. Renal involvement in DRESS syndrome most commonly presents as acute kidney injury due to interstitial nephritis. An 11-year-old boy was referred to the Children's Hospital of Pusan National University because of persistent fever, rash, abdominal distension, generalized edema, lymphadenopathy, and eosinophilia. He previously received vancomycin and ceftriaxone for 10 days at another hospital. He developed acute kidney injury with nephrotic range proteinuria and hypocomplementemia. A subsequent renal biopsy indicated the presence of acute tubular necrosis (ATN) and late exudative phase of postinfectious glomerulonephritis (PIGN). Systemic symptoms and renal function improved with corticosteroid therapy after the discontinuation of vancomycin. Here, we describe a biopsy-proven case of severe ATN that manifested as a part of vancomycin-induced DRESS syndrome with coincident PIGN. It is important for clinicians to be aware of this syndrome due to its severity and potentially fatal nature.

Tumor lysis syndrome following sorafenib treatment in hepatocellular carcinoma

  • Kim, Shin Young;Kim, Hee Yeon;Kim, Yu Seung;Lee, Sang Min;Kim, Chang Wook
    • Journal of Yeungnam Medical Science
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    • 제32권1호
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    • pp.47-49
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    • 2015
  • Sorafenib is indicated for the treatment of advanced hepatocellular carcinoma (HCC), but although rare, tumor lysis syndrome (TLS) can be fatal in HCC patients with a large tumor burden. The authors describe the case of a 55-year-old hepatitis B carrier who visited our clinic with progressive dyspnea for 3 weeks. Chest and abdominal computed tomography revealed a huge HCC in the left lobe of the liver with invasion of the inferior vena cava, right atrium, and pulmonary arteries. After 8 days of sorafenib administration, TLS was diagnosed based on the characteristic findings of hyperuricemia, hyperkalemia, and acute kidney injury with massive tumor necrosis by follow-up imaging. Despite discontinuation of sorafenib and supportive care, the patient's clinical course rapidly deteriorated. The authors describe a rare but fatal complication that occurred soon after sorafenib initiation for HCC. Careful follow-up is required after commencing sorafenib therapy for the early diagnosis and management of TLS.

mRNA In Situ Hybridization으로 확인된 Epstein Barr Virus-Associated Hemophagocytic Syndrome 1례 (A Case of Epstein Barr Virus-Associated Hemophagocytic Syndrome Confirmed by mRNA In Situ Hybridization and Polymerase Chain Reaction)

  • 김정한;양창현;손영모;김호근
    • Pediatric Infection and Vaccine
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    • 제3권2호
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    • pp.200-206
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    • 1996
  • Virus associated hemophagocytic syndrome(VAHS), a class II histiocytosis syndrome, is characterized by high fever, liver dysfunction, coagulation abnormalities, and generalized histiocytic proliferation with marked hemophagocytosis in bone marrow and lymph nodes. VAHS is associated with several viral infections including Epstein Barr virus which has a relatively high mortality rate. We report a fatal case of Epstein Barr virus associated hemophagocytic syndrome and its diagnosis by mRNA in situ hybridization and polymerase chain reaction. A brief review of related literaure is also presented.

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소세포폐암에서 항암화학요법 중 발생한 치명적 종양용해증후군 1예 (Fatal Tumor Lysis Syndrome During Chemotherapy in Small Cell Lung Cancer)

  • 국은희;김민수;안세한;전세용;윤정호;한민성;김철현;이재철
    • Tuberculosis and Respiratory Diseases
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    • 제64권3호
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    • pp.215-218
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    • 2008
  • 고형암에서의 종양용해증후군은 드물지만 발생하면 높은 사망률을 보이는 치명적인 합병증으로 외국에서는 지금까지 약 50여명의 증례가 보고되어 왔다. 우리 나라에서도 종종 발생한다고 알려져 있지만 실제로 뒷받침 할만한 증례를 찾아 보기가 힘든 실정이었다. 이에 저자들은 소세포폐암에서 항암화학요법 도중 발생한 치명적 종양 용해증후군 1예를 경험하였기에 문헌 고찰과 함께 이를 보고하는 바이다.

Boerhaave증후군 환자의 외과적 치료 (Surgical Treatment of Boerhaave's Syndrome)

  • 김동원
    • 대한기관식도과학회지
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    • 제18권1호
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    • pp.9-12
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    • 2012
  • Boerhaave's syndrome is a very fatal condition occuring esophageal rupture during emesis and has the worst prognosis of the esophageal perforation. From May 2007 to March 2012 11 patients underwent surgical treatment for Boerhaave's syndrome at Inje University Sanggye Paik Hospital. There were 11 males whose mean age was 49.9 years ranging from 42 to 59. 2 cases of primary closure was performed and 9 cases of anastomosis using EEA (Esophago-Enteric Anastomisis) stapler. Mean operation time was 154.4 minutes and one patient who undergone primary repair died because of mediastinitis and sepsis on $35^{th}$ post-operative day. There was no leakage at other patients. Post-operative complication was one operative wound infection and one post-operative bleeding which was treated completely. Surgical treatment for Boerhaave's syndrome using EEA stapler is simple and effective technique but further studies with large number of cases should be carried out for better outcome.

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Repeated gastric dilatations leading to fatal abdominal compartment syndrome in a patient with bulimia nervosa

  • ;;;;김지혜
    • 대한응급의학회지
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    • 제29권5호
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    • pp.551-556
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    • 2018
  • Cases of repeated acute gastric dilatations after binge eating in one patient are rarely reported. We report here a case of repeated acute gastric dilatations in a 22-year-old woman with bulimia nervosa. Her repeated acute gastric dilatations seem to have been related to superior mesenteric artery syndrome. On her last visit due to acute gastric dilatation, she underwent emergency gastric decompression surgery because of abdominal compartment syndrome; however, she eventually died because of ischemia reperfusion injury. Emergency physicians should be aware of the need to manage acute gastric dilatation in patients with eating disorder and should pay attention to the signs and distinctive clinical features of abdominal compartment syndrome.

Lemierre syndrome with thrombosis of sigmoid sinus following dental extraction: a case report

  • Kim, Taeyun;Choi, Jin-Young
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • 제39권2호
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    • pp.85-89
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    • 2013
  • Lemierre syndrome is caused by an infection in the oropharyngeal region with subsequent thrombophlebitis in the internal jugular vein. The thrombus from the thrombophlebitis can invade other vital organs, such as liver, lungs, or joints, resulting in secondary infection, which further exacerbates the fatal prognosis of this syndrome. Lemierre syndrome, also called postanginal sepsis or necrobacillosis, was first reported by Dr. Lemierre in 1936. In his report, Lemierre mentioned that out of 20 patients who suffered from this syndrome, only two survived. He also stated that all of the 20 patients complained of infections in the palatine tonsils and developed sepsis and thrombophlebitis in the internal jugular vein. Once called a "forgotten disease," this syndrome showed a very high mortality rate until usage of antibiotics became prevalent. In this case report, the authors present a 71-year-old female patient who suffered from Lemierre syndrome with thrombosis extended to the right sigmoid sinus.

리스페리돈으로 인한 신경이완제 악성 증후군 1례 (A Case of Risperidone-induced Neuroleptic Malignant Syndrome)

  • 강화연;김용구;이민수
    • 생물정신의학
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    • 제5권1호
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    • pp.138-141
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    • 1998
  • Neuroleptic malignant syndrome (NMS) is an uncommon but potentially fatal idiosyncratic reaction to neuroleptics, characterized by muscular rigidity, fever, autonomic dysfunction, and altered consciousness. The major theories to explain NMS is central dopaminergic blockade, but it is unclear. Risperidone is a new antipsychotic drug, a benzisoxazole derivative that blocks dopamine $D_2$ receptor and serotonin type 2 receptor. The comparatively greater serotonin-blocking activity is believed to give risperidone the specific property of not causing any more extrapyramidal side effects than conventional antipsychotics at the optimal dose of 4-8mg/day. It is postulated that risperidone is unlikely to cause NMS. Here, we report a case of risperidone induced neuroleptic malignant syndrome.

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길랭-바레증후군에서 면역글로불린 치료 후 발생한 폐혈전색전증 (Pulmonary Thromboembolism after Intravenous Immunoglobulin Therapy in Guillain-Barre Syndrome)

  • 박진모;김남균;박진성
    • Annals of Clinical Neurophysiology
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    • 제18권1호
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    • pp.14-17
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    • 2016
  • Intravenous immunoglobulin (IVIG) is a safe treatment to treat various neurological disorders, but fatal thrombotic events as rare complications have been reported. A 54-year-old woman with Guillain-Barre syndrome complained of dyspnea during IVIG treatment. She was finally diagnosed with pulmonary thromboembolism. To the best of our knowledge, this is the first case of pulmonary thromboembolism associated with IVIG treatment in a Korean patient with Guillain-Barre syndrome.