• 대한지역사회영양학회:학술대회논문집
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• 대한지역사회영양학회 2004년도 춘계학술대회
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• pp.437.1-437
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• 2004

The protein, called PTP1B (protein tyrosine phosphatase 1B), joins a list of enzymes that mice are associated with obesity. The purpose of this study was to investigate the effects of PTP1B inhibitors and taurine on blood lipid profiles in adolescents obesity model rats. Three week-old thirty-six male Sprague-Dawley rats were randomly assigned to six groups (high fat diet group; HFD group, high fat diet ＋ taurine group; HF＋TR group, high fat diet＋PTP1B inhibitor A group; HF＋A group, high fat diet＋PTP1B inhibitor B; HF＋B group, high fat diet＋PTP1B inhibitor A＋taurine group; HF＋A＋TR group, high fat diet ＋ PTP1B inhibitor B＋taurine group; HF＋B＋TR group).(omitted)

• Nutritional Sciences
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• 제9권3호
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• pp.159-166
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• 2006

This study was performed to investigate antioxidative and anti-aging action of extracts from Sancho (Zanthoxylum schinifolium) leaves. Two extracts were obtained by 80% methanol extraction followed by subsequent fractionation with methylene chloride (MC) and n-butanol (B) and fed at one or three levels to rats on normal level (5%) of fat (control) and high fat(20%) in diets. Male Sprague-Dawley rats weighing about 100 g were divided into ten groups such as control diet group(C), control diet+0.50%B group (CB), control diet+0.50%MC group (CMC), high-fat diet group (HF), high-fat diet+0.25%B group (HBL), high-fat diet+0.50%B group (HBM), high-fat diet+0.75%B group (HBH), high-fat diet+0.25%MC group (HMCL), high-fat diet+0.50%MC group (HMCM) and high-fat diet+ 0.75%MC group (HMCH) and fed each diet for four weeks. The effects of the extracts on antioxidant enzyme activities and indices of lipid peroxidation and aging were seen only in high fat diet groups. Hepatic superoxide dismutase and aryleaterase activities were not changed by Sancho extracts. But glutathione peroxidase, catalase and paraxonase activities were significantly restored by both MC and B at the level of 0.75% lipid peroxide which was increased by high fat diet was significantly reduced by B and MC at the level of 0.25% and over. Lipofuscin fluorescence and cabonyl value were increased by high fat diet were reduced by B and MC at the level of 0.5% and over. It is concluded that the Sancho extracts can be utilized as functional ingredients of health foods for reducing oxidative stress.

• 한국음향학회지
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• 제19권4호
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• pp.101-106
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• 2000

광대역 고분자 초음파 변환기를 이용한 초음파 비선형 파라메타 B/A 측정장치를 이용하여 생체조직에서 지방질의 농도에 대한 B/A의 의존성을 알아보기 위하여 계란의 흰자와 노른자의 혼합에 대하여 조사하였다. 이들 두 성분에 대한 음속과 밀도가 서로 1% 정도임에도 불구하고 yoshizuni등에 의해 제시된 선형성보다 이차적 의존성이 더 있음을 확인하였다. 이것은 생체조직을 fat과 nonfat의 두 부분으로 나누어 지방질의 농도에 대한 초음파 비선형 파라메타 B/A와 음속의 크기에 대하여 본 연구에서 제시한 이론식과 잘 일치하였다. 또한 지방질이 없는 skim milk의 다양한 용해도 성분에 대한 B/A와 음속을 측정한 결과 용해도의 농도가 클수록 B/A와 음속의 값이 커짐을 알 수 있었으며, 이들에 영향을 주는 것은 단백질 등으로 예상된다.

• International Journal of Industrial Entomology and Biomaterials
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• 제9권1호
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• pp.131-135
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• 2004

Oral supplementation with potassium permanganate (30, 50 and 100 $\mu\textrm{g}$) to fifth instar larvae of the ${CSR_2}{\times}{CSR_4}$ race of the silkworm, B. mori resulted in a significant increase in the glycogen content of the fat body and haemolymph trehalose. The protein content of the fat body is also significantly increased in all the potassium permanganate treated groups where as that of the haemolymph is significantly increased only in the 30 ${\mu}g4 fed group. The total lipids content of the fat body increased significantly in all the potassium permanganate treated groups. This indicates that the potassium permanganate may stimulate metabolic activity, there by influencing the biochemical contents in the fat body and haemolymph of the silkworm, B. mori.

• Investigative Magnetic Resonance Imaging
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• 제21권1호
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• pp.28-33
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• 2017

Purpose: To investigate and compensate the effects of respiration-induced B0 variations on fat quantification of the bone marrow in the lumbar spine. Materials and Methods: Multi-echo gradient echo images with navigator echoes were obtained from eight healthy volunteers at 3T clinical scanner. Using navigator echo data, respiration-induced B0 variations were measured and compensated. Fat fraction maps were estimated using $T2^*$-IDEAL algorithm from the uncompensated and compensated images. For manually drawn bone marrow regions, the estimated B0 variations and the calculated fat fractions (before and after compensations) were analyzed. Results: An increase of temporal B0 variations from inferior level to superior levels was observed for all subjects. After compensation using navigator echo data, the effects of the B0 variations were reduced in gradient echo images. The calculated fat fractions show significant differences (P < 0.05) in L1 and L3 between the uncompensated and the compensated. Conclusion: The results of this study raise the need for considering respiration-induced B0 variations for accurate fat quantification using gradient echo images in the lumbar spine. The use of navigator echo data can be an effective way for the reduction of the effects of respiratory motion on the quantification.

• 한국식품영양과학회지
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• 제31권2호
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• pp.277-283
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• 2002

횐쥐 사료에 10%와 20% 수준의 들깨기름, 옥수수기름, 소기름을 각각 배합하여 1개월간 사육한 결과를 비교하니 체중 증가율은 식이 유지 종류에 의한 영향보다도 식이내 유지 함량에 의해 영향을 더 크게 받아 20% 유지군들의 사료 섭취량이 10% 유지군보다 떨어졌음에도 불구하고 20% 유지군들이 10%유지군들보다 체중이 더 증가하였다. 혈중 중성지방량과 총 cholesterol량은 식이내 지방 함량 의존성으로 증가하여 20%유지군들이 10% 유지 군보다 증가하였고 그중에서 소기름군이 가장 높았다. GPT와 BUN값은 식이내 유지 함량 증가에 따라 측정값들이 증가하는 경향이고 20%들깨군의 측정값들은 모두 정상값의 범위를 초과하고 실험군들 중에서 가장 높았다. 혈중 $CO_2$농도는 실험군들 중에서 20% 들깨 기름군이 가장 높았고 정상값을 초과하였다. 나머지 실험군들은 $CO_2$농도 상호간 거의 차이가 없었다. 따라서 흰쥐를 들깨기름의 함량이 높은(20%)사료로 1개월간 사육하였을때 간장 및 기타 장기들의 기능에 약간의 역작용을 주는 것으로 보였다.

• International Journal of Industrial Entomology and Biomaterials
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• 제3권1호
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• pp.7-11
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• 2001

The effect of topical application with 200,400 and 600 $\mu$g/ml 2,4-Dichlorophenoxyacetic Acid (2,4-D) and Naphthoxyacetic Acid (NOA) to the fifth stadium larvae of the silkworm, B. mori on fat body glycogen, protein, total lipids, phospholipids, neutral lipids and haemolymph trehalose and protein has been studied. The fat body glycogen significantly increased in all the groups treated with 2,4-D whereas there is no significantly change in fat body glycogen in all the groups treated with NDA. However, the haemolymph trehalose was significantly increased in all 274-D and NOA treated groups except in the groups treated with 400 and 600 $\mu$g/ml 2,4-D where the increase was not significant.The fat body protein did not show any significant change in all groups treated with 2,4-D and NOA except in the groups treated with 200 $\mu$g/ml 2,4-D where the fat body protein was significantly increased. The total lipids, phospholipids and neutral lipids of the fat body increased significantly in all the groups treated with 2,4-D and NOA when compared with those of the corresponding parameters of the carrier control.

• 한국식품영양학회지
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• 제11권5호
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• pp.475-481
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• 1998

This study was conducted to investigate the possibility for low fat press ham which was made without fat added. Four kinds of press ham were prepared ; Apork 70%, fat 0% ; low fat press ham), B(pork 60%, fat 10%), C(pork 55%, fat 15%) and D(pork 50%, fat 20%). The press ham samples were stored at 4$\pm$2$^{\circ}C$. The physic chemical properties of press hams were analyzed during storage 60 days at 4$^{\circ}C$. The contents of moisture(71.3%) and crude protein (23.4%) of low press ham were higher than those of other products, and crude fat content (2.8%) was remarkably lower(p<0.5). The water holding capacity of press ham was higher than other products. Hunter's L(61.6) and b-value(5.9) of low fat press ham were lower than other products, but a-value(11.7) was higher. Hardness (70.2 dyne/cm), springiness(85%), chewiness(0.49kg), gumminess (2.0kg) and brittleness (0.7kg) of low fat press ham were higher than those of other products, but cohesiveness was lower than D product. Aroma and texture of low fat press ham were inferior to other, but taste and palatability of that were superor.

• Journal of Plant Biotechnology
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• 제46권4호
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• pp.282-290
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• 2019

Cuphea viscosissima plants accumulate medium-chain fatty acids (MCFAs), i.e., those containing 8 ~ 14 carbons, in their seeds, in addition to the longer carbon chain fatty acids (≥16 carbons) found in a variety of plant species. Previous studies have reported the existence of three C. viscosissima MCFA-producing acyl-acyl carrier protein (ACP) thioesterases with different substrate specificities. In this study, CvFatB4, a novel cDNA clone encoding an acyl-ACP thioesterase (EC 3.1.2.14), was isolated from developing C. viscosissima seeds. Sequence alignment of the deduced amino acid sequence revealed that four catalytic residues for thioesterase activity are conserved and a putative N-terminal chloroplast transit peptide is present. Overexpression of CvFatB4 cDNA, which was under the control of the cauliflower mosaic virus 35S promoter, in Arabidopsis thaliana led to an increase in 16:0 fatty acid (palmitate) levels in the seed oil at the expense of 18:1 and other non-MCFAs.

• International Journal of Industrial Entomology and Biomaterials
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• 제2권2호
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• pp.181-184
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• 2001

The effect of topical application with 10, 20 and 30 $\mu\textrm{g}$/ml cortisone and hydrocortisone to the fifth stadium larvae of the silkworm, B. mori on fat body glycogen, protein, total lipids, phospholipids, neutral lipids and haemolymph trehalose and protein has been studied. The fat body glycogen haemolymph trehalose significantly decreased in all the treated groups except in the 10 and 20 $\mu\textrm{g}$/ml treated groups. The fat body protein increased significantly in all the cortisone and hydrocortisone treated groups except in the group treated with 10 $\mu\textrm{g}$ hydrocortisone. Whereas that of haemolymph protein significantly increased in all the groups treated with cortisone and hydrocortisone. The total lipids, phospho1ipids and neutral lipids of the fat body decreased significantly in all the groups treated with cortisone and hydrocortisone when compared with that of carrier control.