• 한국환경성돌연변이발암원학회지
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• 제22권3호
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• pp.169-174
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• 2002

Resveratrol is known to have potent cancer chemopreventive activity against tumorigenesis caused by 7,12-dimetylbenz［$\alpha$］anthracene(DMBA) which is known to be oxidized to reactive products by cytochrome P450 1B1 (CYP1B1). The effects of resveratrol on the activity of recombinant human P450 1 family enzymes, expressed in Escherichia coli membranes with human NADPH-P450 reductase, were determined by measuring alkoxyresorufin O-dealkylation activity, e.g., ethoxyresorufin O-deethylation (EROD) CYP1A1, methoxyresorufin O-demethylation (MROD), CYP1A2, benzyloxyresorufin-O-debenzylation (BROD), CTP1B1. Resveratrol inhibited CYP1B1 and CYP1A1 activities in a dose-dependent manner with $IC_{50}$/ values of 59 and 10$\mu$M for EROD activity and 1.8 and 30$\mu$M for BROD activity, respectively. Resveratrol had only weak inhibitory effect on CYP1A2 activity ($IC_{50}$/ values of 0.44 mM for EROD and ＞2 mM for MROD). Furthermore, resveratrol did not affect NADPH-P450 reductase activity significantly. Resveratrol inhibited the CYP1B1-dependent EROD activity with a $K_{i}$ of 28 $\mu$M in a non-competitive type manner. these results suggest that resveratrol-derived inhibited of CYP1B1 and CYP1A1 activities may contribute to the suppression of DMBA inducible tumorigenesis observed in extrahepatic tissues.s.

• Asian Pacific Journal of Cancer Prevention
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• 제16권18호
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• pp.8487-8490
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• 2016

Background: Helicobacter pylori infection and premalignant gastric mucosa can be reliably identified using conventional narrow band imaging (C-NBI) gastroscopy. The aim of our study was to compare standard biopsy with site specific biopsy for diagnosis of H. pylori infection and premalignant gastric mucosa in daily clinical practice. Materials and Methods: Of a total of 500 patients who underwent gastroscopy for investigation of dyspeptic symptoms, 250 patients underwent site specific biopsy using C-NBI (Group 1) and 250 standard biopsy (Group 2). Sensitivity, specificity, and positive and negative predictive values were assessed. The efficacy of detecting H. pylori associated gastritis and premalignant gastric mucosa according to the updated Sydney classification was also compared. Results: In group 1 the sensitivity, specificity, positive and negative predictive values for predicting H. pylori positivity were 95.4%, 97.3%, 98.8% and 90.0% respectively, compared to 92.9%, 88.6%, 83.2% and 76.1% in group 2. Site specific biopsy was more effective than standard biopsy in terms of both H. pylori infection status and premalignant gastric mucosa detection (P<0.01). Conclusions: Site specific biopsy using C-NBI can improve detection of H. pylori infection and premalignant gastric mucosa in daily clinical practice.

• 가족자원경영과 정책
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• 제6권2호
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• pp.31-52
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• 2002

This study classified consumers' behaviors of purchasing gifts, divided groups by the types of similar behaviors, and examined impacts of demographic variables, relevant variables in purchasing processes on those behaviors. Findings of this study can be summarized as follows. First, factors explaining consumers' behaviors of purchasing gifts were the tendency of demonstrative purchase, the level of placing values to the meaning of gifts, the level of altruism and rationality in the purchase of gifts, and the tendency of impulsive purchase. On the basis of these five factors, five distinct consumer groups showing similar behaviors of purchasing gifts based on the results of Cluster analysis were identified. Those groups were impulsiveㆍdemonstrative groups, impulsiveㆍnon-sincere groups, indifferent groups, non-impulsiveㆍdemonstrative groups, non-altruistic'ㆍrational groups, sincere groups, and altruisticㆍrational groups. Second, behaviors of purchasing gifts showed significant differences depending on gender, educational levels, occupational types, and women's employment status. Consumers with high education, professional occupation, high income tended to show the demonstrative purchase. Male consumers were not interested in the purchases of gifts and placed high values on the meanings of gifts. In contrast, female consumers showed rational behavior, but revealed the tendency of demonstrative in the purchase of gifts as well. Finally, behaviors of purchasing gifts were also different depending on the method of gathering consumer information, places of purchasing gifts, experiences of ordering paid wrapping gifts and the relevant costs, consumers' evaluations of the purchases of gifts, and degrees of satisfaction after the purchase of gifts. Impulsive'ㆍdemonstrative groups and non-impulsive'ㆍ demonstrative groups preferred departments as places of purchasing gifts and choose ordering paid wrapping gifts but showed dissatisfactions after purchases of gifts. Consumers who belongs to non-altruistic'ㆍrational groups, sincere groups, and altruistic'ㆍ rational groups tended to prefer local stores in their own villages as places of purchasing gifts and did not order paid wrapping gifts while showing high after the purchase of gifts.

• 한국생활과학회지
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• 제24권2호
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• pp.297-325
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• 2015

The purpose of this research is to analyze content elements of Housing area in 2013 middle school Technology Home Economics textbooks 1 and 2, total of 22 according to 2009 revised curriculum. The analysis method was content analysis, focusing on contents of main text, tables & figures, reading material, and activity materials by their content elements. This research will contribute in obtaining suggestion for the post curriculum/textbook development and helping teachers to perform a lesson. The results are as follows. First, Housing area included 1 to 4 content elements per each units, from 2 chapters and 6 units. The content elements stated in Home economics curriculum were total of 16 which consists of 'the meaning of housing,' 'housing types,' 'family forms,' 'family life style cycle,' 'life style,' 'neighboring environment,' 'co-living values,' 'air environment,' 'heat environment,' 'light environment,' 'acoustic environment,' 'space division,' 'circulation', 'effective use of space,' and 'sustainable dwelling practice.' All of these components are dealt with in every textbooks. Second, the numbers of content elements provided in each textbooks were the same, however they showed difference in their contextual aspect. Some contents need supplemental material for their lacking content element. Others need proper understanding of the concept because some showed different contents from the appropriate content elements. Third, repetitions in content elements were observed, the contents of 'co-living values' in textbook 1 and 'sustainable dwelling practice' in textbook 2 were similar in terms of eco-friendly housing, co-housing and universal housing. These two content elements should be merged as one next curriculum, or should be stated together in one subunit.

• 환경영향평가
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• 제20권5호
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• pp.729-745
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• 2011

The purpose of this paper is to estimate the external diseconomies of an unwelcomed facility on the nearby houses. The facility and the area studied are Dangin-Ri power plant in Mapo-Gu, Seoul and the residential district surrounding it respectively. The nearby housing prices have been changed according to the time and circumstances of the public announcements about the reconstruction or removal plans of the plant. These price changes are regarded as the capitalized values of the external diseconomies due to the plant. This study is based on the hedonic price theory in order to estimate the diseconomies in monetary value. The tools for the estimation are four models of multiple regression with the transaction price as the dependant variable and various housing characteristics including the external effects of the plant as the independent variables. The sample analyzed is 833 house transactions for the past 5 years in the research area. The facts found are as follows; First, the most suitable functional form for the estimation is confirmed to be the linear model. Second, there are significant differences in influence on the housing values among the independent variables, that is, locational characteristics, physical features, and environmental changes with time. Third, the external diseconomy is estimated as \80,137,807 in case that the plant would be reconstructed in the underground of the present site, whereon a substitutional public park would be constructed and as \59,142,248 in case that the plant would move away.

• Journal of Microbiology and Biotechnology
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• 제32권7호
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• pp.855-861
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• 2022

A white-pigmented, non-motile, gram-negative, and rod-shaped bacterium, designated CYS-02^T, was isolated from soil sampled at Suwon, Gyeonggi-do, Republic of Korea. Cells were strictly aerobic, grew optimally at 20-28℃ and hydrolyzed Tween 40. Phylogenetic analysis based on 16S rRNA gene sequence indicated that strain CYS-02^T formed a lineage within the family Comamonadaceae and clustered as members of the genus Variovorax. The closest members were Variovorax guangxiensis DSM 27352^T (98.6% sequence similarity), Variovorax paradoxus NBRC 15149^T (98.5%), and Variovorax gossypii JM-310^T (98.3%). The principal respiratory quinone was Q-8 and the major polar lipids contain phosphatidylethanolamine (PE), phosphatidylethanolamine (PG), and diphosphatidylglycerol (DPG). The predominant cellular fatty acids were C_16:0, summed feature 3 (C_16:1ω7c and/or C_16:1ω6c) and summed feature 8 (C_18:1ω7c and/or C_18:1ω6c). The DNA GC content was 67.7 mol%. The ANI and dDDH values between strain CYS-02T and the closest members in the genus Variovorax were ≤ 79.0 and 22.4%, respectively, and the AAI and POCP values between CYS-02^T and the other related species in the family Comamonadaceae were > 70% and > 50%, respectively. The genome of strain CYS-02^T showed a putative terpene biosynthetic cluster responsible for antioxidant activity which was supported by DPPH radical scavenging activity test. Based on genomic, phenotypic and chemotaxonomic analyses, strain CYS-02^T was classified into a novel species in the genus Variovorax, for which the name Variovorax terrae sp. nov., has been proposed. The type strain is CYS-02^T (= KACC 22656^T = NBRC 00115645^T).

• 예술인문사회 융합 멀티미디어 논문지
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• 제8권2호
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• pp.657-666
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• 2018

본 연구는 중국계 결혼이주여성들은 결혼생활에서 양성평등에 대해 어떠한 생각을 가지고 있는지 문제점은 무엇인지 알아보기 위하여 진행되었다. 연구를 위하여 한국인 남성과 결혼한 중국계 결혼이주여성 5명을 심층 인터뷰하였다. 연구방법은 질적연구방법인 사례연구 방법을 활용하여 5명의 연구참여자들의 이주전 양성평등 인식과 이주 후 양성평등 갈등 사례를 분석하였다. 연구결과 결혼이주여성들의 양성평등 인식차이로 나타나는 부부갈등은 본국의 가족생활문화, 남편과의 만남의 경로, 남편의 중국문화에 대한 이해 정도에 따라 각각 다른 양상으로 드러났다. 그럼에도 불구하고 대부분의 연구참여자들은 한국사회에 적극적으로 동화하려는 시도로 불평등을 감수하면서도 한국형 가부장제에 순응하는 모습의 형태로 한국형 여성가치관을 수용하는 모습을 보여주고 있었다. 그리고 그중 일부는 한국인 남편의 가부장적 가치관 때문에 가정이 파탄되는 결과를 가져오기도 하였다. 이런 연구결과를 바탕으로 한국사회 다문화가정 양성평등에 있어서 문제점은 무엇인지 그리고 개선방안에 대하여 논의하였다.

• 문화기술의 융합
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• 제9권5호
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• pp.761-767
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• 2023

본 연구는 미혼여성의 결혼관, 자녀관, 성역할관, 일·가정양립 인식정도를 파악하고, 결혼관에 영향을 주는 요인을 확인하여, 결혼에 대한 긍정적 가치관을 심어주기 위한 방안을 마련하기 위해 시도되었다. 충북지역 미혼여성 508명을 대상으로 구조화된 설문지를 통해 2022년 5월부터 8월까지 자료를 수집하였다. 수집된 자료는 SPSS/WIN 22.0을 이용하여 분석하였다. 미혼여성의 결혼관은 2.92점(5점), 자녀관은 3.32점(5점), 성역할관 1.70점(5점), 일·가정양립 인식 정도는 2.85점(5점)으로 나타났다. 미혼여성의 결혼관은 자녀관, 일·가정양립 인식과 유의한 상관관계가 있는 것으로 나타났으며, 미혼여성의 결혼관에 영향을 주는 요인은 자녀관과 성역할관이었다. 이들 변인이 결혼관을 설명하는데 48%의 영향력을 나타냈다. 이를 바탕으로 미혼여성들에게 결혼에 대한 긍정적 가치관을 향상시킬 수 있는 방안을 모색하는데 기초자료로 활용할 수 있을 것이다.

• 한국콘텐츠학회논문지
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• 제18권4호
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• pp.60-76
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• 2018

본 연구문제를 검증하기 위한 자료 수집은 서울지역 소재지 복무기관에서 복무 중인 사회복무요원을 대상으로 설문지 총 470부를 배부하여 427부를 통계분석자료로 사용하였다. 측정도구는 자아분화수준 척도, 자아탄력성 척도, 복무 부적응행동 척도를 사용하였으며, 연구문제 검증을 위한 통계처리는 일원변량분석, 상관분석, 중다회귀분석을 실시하였다. 본 연구의 결론은 다음과 같다. 첫째, 사회복무요원의 관련변인에 대한 전반적인 경향성을 살펴본 결과, 자아분화와 자아탄력성은 중간점수보다 약간 높은 수준이었고, 복무부적응행동은 보통보다 약간 낮은 수준으로 사회복무요원들이 대체로 복무에 적응을 잘 하는 것으로 나타났다. 둘째, 사회복무요원의 인구사회학적 특성, 자아분화와 자아탄력성이 복무 부적응행동에 미치는 상대적 영향력을 알아본 결과, 복무 부적응행동의 모든 하위변인에 인구사회학적 특징, 자아분화와 자아탄력성이 모두 유의미한 영향을 주었다. 사회적 위축에는 대인관계 효율성, 낙관적 태도, 가족퇴행 분화수준이 부적인 영향을 미쳤고, 정서적 단절, 학력, 복무기간이 정적인 영향을 미치는 것으로 나타났다. 과잉행동에는 가족퇴행 분화수준, 분노조절, 인지 대 정서가 부적인 영향을 주었고, 자아통합은 정적인 영향을 주었다. 공격성에는 가족퇴행과 인지 대 정서의 분화수준, 분노조절, 가정의 경제적 수준이 부적인 영향을 미쳤다. 강박성에는 가족퇴행, 낙관적 태도, 인지 대 정서, 가정의 경제적 수준, 복무기간이 부적인 영향을 주는 것으로 나타났다.

• 가족자원경영과 정책
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• 제20권4호
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• pp.1-17
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• 2016

The purpose of this study was to investigate the effect of family characteristics of the baby boomer generation on the level of their later life preparation. This study randomly sampled a birth cohort between 1955 and 1963 consisting of participants living in Seoul, South Korea with a spouse and a child/children. This study investigated a total of 455 subjects from March 2 to March 20, 2016. The study findings are summarized as follows. This study analyzed the characteristics of baby boomers' family relationships and their effects on their later life preparation. It was found that 55.4% of the subjects had at least 2 children, and 44.6% had 1 child. Concerning their children's marital status, 33.8% had married children and 66.2% had unmarried children. The level of their children's support was found at 2.82 points (standard deviation [SD] = .64), which is slightly higher than the mean value of 2.5. The spouse satisfaction among the subjects was found to be 3.59 (.79) which is higher than the mean value of 3. The general status of later life preparation was 2.70 (SD = .44), which is lower than the mean value of 3. In the sub-dimension, the level of social preparation was 2.98 points (SD = .61); the level of economic preparation was 2.60 (SD = .64); and the level of physical preparation was 2.53 (SD = .45). All the values were lower than the mean value of 3. The overall status of later life preparation of the subjects in this study was low. The physical preparation level was particularly low. To analyze the factors that affect baby boomers' later life preparation, a hierarchical regression analysis was implemented. As a result, a significant effect was found in specific factors, such as spouse satisfaction (${\beta}$ = .32, p < .001), age (${\beta}$ = .26, p < .001), number of children (${\beta}$ = -.18, p <.001), health status (${\beta}$ = .18, p < .001), gender (${\beta}$ = -.11, p < .05), household income (${\beta}$ = .10, p < .05), and children's marital status (${\beta}$ = .10, p < .05). That is, the higher the spousal satisfaction, the older the age, and the lower the number of children, the higher the levels of later life preparation. Further, a higher level of later life preparation was observed in women, those with higher household incomes, and those with married children.