• Korean Journal of Child Studies
• /
• v.26 no.4
• /
• pp.71-84
• /
• 2005

Eighty-eight 5-year-old subjects were tested by the Torrance Tests of Creative Thinking, and randomly assigned to experimental(n=44) or control(n=44) groups. Developed in collaboration with kindergarten teachers, physical activity projects were based on themes from "life and health" and "life as expression" of the kindergarten curriculum. The resulting program consisting of 24 activities was applied to the experimental group for 24 sessions. Data were analyzed by mean, standard deviation, and repeated measures ANOVA. Effectiveness of the physical activity program for enhancing creativity was shown by a significant increase in mean creativity scores of the experimental group and in the sub-scores of fluency, originality, abstraction of title, elaboration, and resistance to an impetuous ending.

• Journal of Life Science
• /
• v.15 no.2 s.69
• /
• pp.192-196
• /
• 2005

The SNF2/SW12 family comprises proteins from a variety of species with in vivo functions, such as transcriptional regulation, maintenance of chromosome stability during mitosis, and various types of DNA repair. This study was shown the characterization of hrp2+ gene which was isolated by PCR amplification using the conserved domain of SNF2 motifs. Sequence analysis of hrp2+ gene showed striking evolutionary conservation among the SNF2 family of proteins. The transcript of hrp2+ gene was found to be a 4.7 kb as identified by Northern hybridization. To investigate the inducibility of hrp2+ gene, transcript levels were examined after treating the cells to various DNA damaging agents. The transcripts of hrp2+ were induced by UV-irradiation. But the transcripts were not induced by treatment of $ 0.25\%$ Methylmethane sulfonate (MMS). These results implied that the effects of damaging agents are complex and different regulatory pathways exist for the induction of this gene. Hrp2 protein was purified near homogeneity by combination of affinity chromatography. We tested the purified Hrp2 protein for the helicase activity in an oligonucleotide release assay. However we were unable to detect any helicase activity associated with the Hrp2 protein, indicating that the helicase motifs in Hrp2 are merely indicators of a broader DNA-dependent ATPase activity.

• Hwankyungkyoyuk
• /
• v.17 no.1
• /
• pp.1-11
• /
• 2004

The objectives of this study were: a) to measure the satisfaction of who volunteered in the activity, and b) to identify factors related to their satisfaction from the activities, and c) to provide policy implications to improve their satisfaction. This study was based on a literature review and empirical analyses. The empirical analyses have been completed through individual interviews with community residents who volunteer the NGO activities in the Korean Federation for Environmental Movement. The major findings from empirical analysis were as follows: As a result of correlation analysis, nine variables affecting the degree of their satisfaction were "activity time", "sex", "support of family and friends", "understanding of environmental NGO activities and fields of environmental NGO activities", "contact points for the activities", "income and vocation". As a result of multiple regression analysis, the five variables affecting the degree of their satisfaction were "understanding of the NGO activities", "income", "support of family", "marital status", "activity period" and these five variables explained 49.1% of the degree of their satisfaction. Based on the empirical findings, the following suggestions could be offered for the environmental NGO activities. 1) Environmental NGOs should offer resident-friendly programs which may help the residents participate in the NGO activities, so the volunteers can participate in the activities with their family, friends, and neighbors. 2) Environmental NGOs should provide appropriate information and educational supports to community residents, which might facilitate them to have a sound understanding of the NGO activities. And the environmental NGOs should provide diverse activity programs to facilitate participation and to formulate eligible management system for the activities. 3) To enhance the satisfaction of participation, environmental action programs should be organized and conducted through a careful consideration of the status of the community, the characteristics of residents, and so on. To provide better contact points, environmental NGOs should cooperate with religious organizations in communities, social groups, media and so on.

• Journal of Korean Home Economics Education Association
• /
• v.30 no.1
• /
• pp.79-97
• /
• 2018

The purpose of this study was to analyze the democratic civic competencies of the activity tasks in 'the Family Life' part in Middle School Technology Home Economics textbooks according to the 2015 revised national curriculum. In order to achieve the purpose of this study, the activity tasks of six types of middle school Home Economics textbooks (for a total 12 of volumes) were analyzed. As a result, the use of the citizenship competency group was the most often recorded out of the three democratic civic competency groups and the subset of trust and value competencies also were frequently observed. Additionally, democratic civic competency was the seen most within the 'human development and family' area by the national curriculum, and showed the highest frequency in big idea, 'the relationship'. Activity tasks in the 'KH' textbooks were dealing with democratic civic competency the most. Based on the relationship between Home Economics education and democratic civic competencies, it is necessary to study the practice of classroom instruction so that students can develop democratic civic competence in 'the Family Life' by means of a Home Economics curriculum.

• Proceedings of the Korean Society of Applied Pharmacology
• /
• 2002.07a
• /
• pp.113-113
• /
• 2002

Phylogenetically conserved Bcl-2 family proteins play a pivotal role in the regulation of apoptosis from virus to human. Members of the Bcl-2 family consist of antiapoptotic proteins such as Bcl-2, Bcl-xL, and Bcl-w, and proapoptotic proteins such as BAD, Bax, BOD, and Bok. It has been proposed that anti- and proapoptotic Bcl-2 proteins regulate cell death by binding to each other and forming heterodimers. A delicate balance between anti- and proapoptotic Bcl-2 family members exists in each cell and the relative concentration of these two groups of proteins determines whether the cell survives or undergoes apoptosis. Mcl-1 (Myeloid cell :leukemia-1) is a member of the Bcl-2 family proteins and was originally cloned as a differentiation-induced early gene that was activated in the human myeloblastic leukemia cell line, ML-1 . Mcl-1 is expressed in a wide variety of tissues and cells including neoplastic ones. We recently identified a short splicing variant of Mcl-1 short (Mcl-IS) and designated the known Mcl-1 as Mcl-1 long (Mcl-lL). Mcl-lL protein exhibits antiapoptotic activity and possesses the BH (Bcl-2 homology) 1, BH2, BH3, and transmembrane (TM) domains found in related Bcl-2 proteins. In contrast, Mcl-1 S is a BH3 domain-only proapoptotic protein that heterodimerizes with Mcl-lL. Although both Mc1-lL and Mcl-lS proteins contain BH domains fecund in other Bcl-2 family proteins, they are distinguished by their unusually long N-terminal sequences containing PEST (proline, glutamic acid, serine, and threonine) motifs, four pairs of arginine residues, and alanine- and glycine-rich regions. In addition, the expression pattern of Mcl-1 protein is different from that of Bcl-2 suggesting a unique role (or Mcl-1 in apoptosis regulation. Tankyrasel (TRF1-interacting, ankyrin-related ADP-related polymerasel) was originally isolated based on its binding to TRF 1 (telomeric repeat binding factor-1) and contains the sterile alpha motif (SAM) module, 24 ankyrin (ANK) repeats, and the catalytic domain of poly(adenosine diphosphate-ribose) polymerase (PARP). Previous studies showed that tankyrasel promotes telomere elongation in human cells presumably by inhibiting TRFI though its poly(ADP-ribosyl)action by tankyrasel . In addition, tankyrasel poly(ADP-ribosyl)ates Insulin-responsive amino peptidase (IRAP), a resident protein of GLUT4 vesicles, and insulin stimulates the PARP activity of tankyrase1 through its phosphorylation by mitogen-activated protein kinase (MAPK). ADP-ribosylation is a posttranslational modification that usually results in a loss of protein activity presumably by enhancing protein turnover. However, little information is available regarding the physiological function(s) of tankyrase1 other than as a PARP enzyme. In the present study, we found tankyrasel as a specific-binding protein of Mcl-1 Overexpression of tankyrasel led to the inhibition of both the apoptotic activity of Mel-lS and the survival action of Mcl-lL in mammalian cells. Unlike other known tankyrasel-interacting proteins, tankyrasel did not poly(ADP-ribosyl)ate either of the Mcl-1 proteins despite its ability to decrease Mcl-1 proteins expression following coexpression. Therefore, this study provides a novel mechanism to regulate Mcl-1-modulated apoptosis in which tankyrasel downregulates the expression of Mcl-1 proteins without the involvement of its ADP-ribosylation activity.

• Korean Journal of Breeding Science
• /
• v.40 no.2
• /
• pp.136-142
• /
• 2008

We conducted this study to compare physiological response according to growing conditions between superior and inferior family of Pinus densiflora. In 1981, open-pollinated (OP) progenies of P. densiflora were planted in Chuncheon (CC) and Naju (NJ). We selected KW2 as a superior family and KW23 as a inferior family based on volume index among 30 OP progenies. We calculated general combining ability of each 30 OP progenies in each sites, and compared family growth rank. We collected needles of selected families in CC and NJ, and analyzed chlorophyll content, nitrated reductase (NR) activity, nitrogen content, and superoxide dismutase (SOD) acitivity. In CC, chlorophyll content and nitrogen content were more in needles of KW2 than those of KW23. In NJ, KW2 showed higher NR activity than KW23, and according to site, families in CC showed higher NR activity than those in NJ. SOD activities of both families were higher in NJ, and KW23 showed higher activity than KW2 in both sites. Consequently, inconsistency of the growth performance of two families was caused by different genetic and physiological responses.

• Journal of Family Resource Management and Policy Review
• /
• v.17 no.3
• /
• pp.39-58
• /
• 2013

The purpose of this study was to identify the factors determining the participation of the poor elderly in economic activity. This study analyzed secondary data of the second wave of Korean Longitudinal Study of Ageing. Binary logistic regression was used to identify the factors that are associated with the economic activity of the poor elderly. The results of the analyses showed that age, gender, region, public assistance, education, health status, chronic illness, contacts with acquaintances, and support from children were associated with participation in economic activity. The study's findings have several implications for policies and services. The study identified the need for an age- and gender-specific approach to promoting participation in economic activity among the poor elderly. Regional differences should also be considered in the creation of work opportunities for older adults. In terms of human capital, the positive effect of good health indicates that strategies are needed to address the needs of older adults with health issues. In addition, there is a need for more jobs for elderly job seekers with high levels of education. Finally, policy makers and practitioners should explore interventions for enhancing the social network involvement and community support for the elderly living in poverty.

• Journal of the Korean Home Economics Association
• /
• v.42 no.12 s.202
• /
• pp.231-251
• /
• 2004

The purpose of this study us to determine the adolescents' leisure activity pattern, leisure constraints and leisure satisfaction and to identify the relevant variables. The subjects were middle and high school students. The data was collected by using the questionnaire and the final 741 cases were analyzed by SPSS Win 10.0 program. The major findings were as follows: 1. The adolescents' leisure activity hours were 2.27hours/day(weekday), 4.20hours/day(Saturday) and 5.35hours/day(Sunday). On weekdays, female students spent more time for leisure activity than male students. The most frequent activities were watching TV and playing computer. 2. The adolescents' leisure constraints were social-economic, psychological and situational. The degree of the adolescents' situational constraint was the highest. 3. The adolescents' leisure satisfactions were leisure use, leisure condition and leisure meaning. The adolescents' degree of leisure meaning satisfaction was relatively high. 4. The major related variable influencing the leisure satisfaction were psychological constraint, situational constraint and gender.

• Proceedings of the Korean Society of Applied Pharmacology
• /
• 1998.11a
• /
• pp.172-173
• /
• 1998

A research collection of Pseudomons solanacearum bacteria, a pathogen causing ‘bacteria wilt’ disease of more than 265 plant species, represented for northern provinces of Vietnam has recently been established and was saved for examination of antifungal activity in their culture fluids. All strains used in this work have been isolated from infected tomato, potato, and groundnut collected from production fields and they express different levels of virulence on their host plants. Cell-free culture fluids of these strains were tested for antifungal activity (to inhibit growth of mycelium and to destroy germination tube of fungal spores) on a number of fungi that either infect or associate with vegetable crops of Solanaceae family (tomato, potato, pepers...), fruit plants (banana), and even well-known by Vietnamese traditional medicine herbal plants belonging to Trifoliatus, Schefflera, Homalomena and Panax genera (Araliaceae family) of which roots are used as a resource of the herbal material. The antifungal activity was found in nearly all strains tested. Result of study on chitin, CMC, tween 80 and casein degradation abilities of the latter suggested that antifungal activity of positively-found strains may be due to their ability of extracelluar chitinase's excretion that destroy fungal cell wall.

• Journal of Families and Better Life
• /
• v.7 no.2
• /
• pp.15-30
• /
• 1989

This study deals with the following problems about leisure activity of young people and leisure guidance of mothers, (1) Leisure activity of children by the independent variables, (2) Leisure guidance of mothers by the independent variables. (3) The relation between leisure guidance of mothers and leisure activity of young people. This research used the questionaire survey. The subjects were 830 couples of mother and pupil (pupils of 4, 5 and t grades in six primary school in Kwang-Ju city). The statistics used for data analysis were percentage, t, F-test, X2. The results of this study are summarized as follows; (1) Boys and girls average leisure hours: week days…2 hour, saturday…3 hours, Sunday and holiday…4.5 hours, the school vacation…6.2 hours. And leisure activity showed the significant difference in sex, age, educational level, family form (p 0.001, p 0.05, p 0.010). Generally, they had social & amusing leisure activity. And a hindrance cause of leisure activ ty is due to hard working in learning practice. (2) The necessity of leisure activity showed higher in the aged mother and high educated mother, lower in the poor family. And guidance content showed the significant difference in sex of children(p 0.001), educational level of parents(p 0.05). Actually mothers wanted intellectual leisure activity. (3) The relation between the leisure activity pattern desired by leisure activity of mothers and children pattern showed that mothers demanded the various patterns, but children wanted social & amusing leisure activities mainly. Only children's patterns agreed with mothers in the artistic, intellectual, activities on Saturday and during the vacation. And the relation between mothers satisfaction degree in the leisure activity of children and children's satisfaction degree showed the significant difference (p 0.05). Children's satisfaction degree is high, irrespective of mothers satisfaction degree.