• Analytical Science and Technology
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• v.33 no.3
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• pp.115-124
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• 2020

Marker pens belong to school things that are controlled by the regulation system called safety confirmation under special act on the safety of products for children with the formaldehyde criteria of 20 mg/kg. With nine marker pens available commercially, formaldehyde in marker pen ink was analyzed by present test standard where marking on a fabric swatch with a pen and extracting the swatch in water and derivatization with Nash reagent followed by UV/Vis spectrophotometeric measurement (Nash-UV/Vis method), giving not detected results or a false positive result in case of a colored water extract. However, the contents of formaldehyde in ink of nine marker pens were determinded to range between 3.2 ~ 93.2 mg/kg with three results above the safety criteria of 20 mg/kg by HPLC/DAD measurements on DNPH derivatives of formaldehyde (DNPH-HPLC/DAD method) in ink dissolved directly in water using an ultrasonic bath. Therefore, the DNPH-HPLC/DAD method with the extraction of ultrasonic dissolving ink in water is proposed as a proper method for analyzing formaldehyde in ink. The proposed method has advantages of lower detection limit and accuracy with colored extracts as well as a simple and fast extraction. The accuracy and precision of this method was estimated to be 90.1 ~ 105.4 % and 0.6 ~ 3.3 %, respectively by spiking tests in the ranges of 20 mg/kg and 40 mg/kg using matrixes such as highlighter pen ink, board marker ink, chalk marker pen ink and painter marker ink.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.39B no.11
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• pp.779-789
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• 2014

Cognitive radio (CR) technology based on geo-location database access approach and/or wideband spectrum sensing approach is absolutely vital in order to recognize available frequency bands in white spaces (WSs), and efficiently utilize shared spectrums. This paper presents a new structure for the TVWS database access protocol implementation based on Internet Engineering Task Force (IETF) Protocol to Access WS database (PAWS). A wideband compressive spectrum sensing (WCSS) scheme using a modulated wideband converter is also proposed for the TVWS utilization. The developed database access protocol technology which is adopted in both the TV band device (TVBD) and the TVWS database operates well in the TV frequency bands. The proposed WCSS shows a stable performance in false alarm probability irrespective of noise variance estimation error as well as provides signal detection probabilities greater than 95%. This paper also investigates Federal Communications Commision (FCC) regulatory requirements of TVWS database as well as European Telecommunications Standards Institute (ETSI) policy related to TVWS database. A standardized protocol to achieve interoperability among multiple TVBDs and TVWS databases, which is currently prepared in the IETF, is discussed.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.49 no.3
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• pp.227-231
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• 2004

A total of 219 polymerase chain reaction tests of genetically modified (GM) DNA sequences in soybean seeds and soybean sprouts were conducted during 2000-2001. No CM gene was found in 96 tests of soybean seeds. However, either a functional CP4EPSPS gene or the 355 promoter gene was found three times in 2000 and eight times in 2001, in between 0.01 and 0.17％ of soybean spout products, in 123 tests. Since the amount of GM genes was much less than the threshold limit of 3％, none of the 11 positive soybean-sprout samples needed to be libeled GM crops. Of these, seven sprout samples were from domestic seeds and four were from seeds imported from China. To find the contamination route, the raw materials, seed surface, floor of the storage room, area around the selection machine, surface of the packaging film and corn powder used in the package were tested. The 35S promoter gene was detected in only two samples of the corn powder (0.1％). Although we could not find the cause of the GM contamination, the sprout package film is one possibility. In total,8.9％ of the soybean sprout tests were GM positive, but the amounts were much less than the threshold of 3％. This means that there are frequent false-positives and these would threaten the sprout industry if GMO were decided qualitatively. Food companies should make their safety data available to the public and make an effort to address people's concerns about GM food more openly. In addition, there is a need to establish a quantitative test for GM genes in sampled water and a sampling method for raw materials.

• Asian-Australasian Journal of Animal Sciences
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• v.33 no.5
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• pp.704-711
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• 2020

Objective: Muscle fiber types, numbers and area are crucial aspects associated with meat production and quality. However, there are few studies of pig muscle fibre traits in terms of the detection power, false discovery rate and confidence interval precision of whole-genome quantitative trait loci (QTL). We had previously performed genome scanning for muscle fibre traits using 183 microsatellites and detected 8 significant QTLs in a White Duroc×Erhualian F₂ population. The confidence intervals of these QTLs ranged between 11 and 127 centimorgan (cM), which contained hundreds of genes and hampered the identification of QTLs. A whole-genome sequence imputation of the population was used for fine mapping in this study. Methods: A whole-genome sequences association study was performed in the F₂ population. Genotyping was performed for 1,020 individuals (19 F₀, 68 F₁, and 933 F₂). The whole-genome variants were imputed and 21,624,800 single nucleotide polymorphisms (SNPs) were identified and examined for associations to 11 longissimus dorsi muscle fiber traits. Results: A total of 3,201 significant SNPs comprising 7 novel QTLs showing associations with the relative area of fiber type I (I_RA), the fiber number per square centimeter (FN) and the total fiber number (TFN). Moreover, one QTL on pig chromosome 14 was found to affect both FN and TFN. Furthermore, four plausible candidate genes associated with FN (kinase non-catalytic C-lobe domain containing [KNDC1]), TFN (KNDC1), and I_RA (solute carrier family 36 member 4, contactin associated protein like 5, and glutamate metabotropic receptor 8) were identified. Conclusion: An efficient and powerful imputation-based association approach was utilized to identify genes potentially associated with muscle fiber traits. These identified genes and SNPs could be explored to improve meat production and quality via marker-assisted selection in pigs.

• KIPS Transactions on Software and Data Engineering
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• v.7 no.3
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• pp.77-90
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• 2018

Software Defect Prediction (SDP) is a field of study that identifies defective modules. With insufficient local data, a company can exploit Cross-Project Defect Prediction (CPDP), a way to build a classifier using dataset collected from other companies. Most machine learning algorithms for SDP have used more than one parameter that significantly affects prediction performance depending on different values. The objective of this study is to propose a parameter selection technique to enhance the performance of CPDP. Using a Harmony Search algorithm (HS), our approach tunes parameters of cost-sensitive boosting, a method to tackle class imbalance causing the difficulty of prediction. According to distributional characteristics, parameter ranges and constraint rules between parameters are defined and applied to HS. The proposed approach is compared with three CPDP methods and a Within-Project Defect Prediction (WPDP) method over fifteen target projects. The experimental results indicate that the proposed model outperforms the other CPDP methods in the context of class imbalance. Unlike the previous researches showing high probability of false alarm or low probability of detection, our approach provides acceptable high PD and low PF while providing high overall performance. It also provides similar performance compared with WPDP.

• Clinical and Experimental Pediatrics
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• v.56 no.6
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• pp.247-253
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• 2013

Purpose: In children with acute leukemia, bone marrow genetic abnormalities (GA) have prognostic significance, and may be the basis for minimal residual disease monitoring. Since April 2007, we have used a multiplex reverse transcriptase-polymerase chain reaction tool (HemaVision) to detect of GA. Methods: In this study, we reviewed the results of HemaVision screening in 270 children with acute leukemia, newly diagnosed at The Catholic University of Korea from April 2007 to December 2011, and compared the results with those of fluorescence in situ hybridization (FISH), and G-band karyotyping. Results: Among the 270 children (153 males, 117 females), 187 acute lymphoblastic leukemia and 74 acute myeloid leukemia patients were identified. Overall, GA was detected in 230 patients (85.2%). HemaVision, FISH, and G-band karyotyping identified GA in 125 (46.3%), 126 (46.7%), and 215 patients (79.6%), respectively. TEL-AML1 (20.9%, 39/187) and AML1-ETO (27%, 20/74) were the most common GA in ALL and AML, respectively. Overall sensitivity of HemaVision was 98.4%, with false-negative results in 2 instances: 1 each for TEL-AML1 and MLL-AF4. An aggregate of diseases-specific FISH showed 100% sensitivity in detection of GA covered by HemaVision for actual probes utilized. G-band karyotype revealed GA other than those covered by HemaVison screening in 133 patients (49.3%). Except for hyperdiplody and hypodiploidy, recurrent GA as defined by the World Health Organizationthat were not screened by HemaVision, were absent in the karyotype. Conclusion: HemaVision, supported by an aggregate of FISH tests for important translocations, may allow for accurate diagnosis of GA in Korean children with acute leukemia.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.5
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• pp.451-457
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• 2020

Format recognition and OCR techniques are widely used as methods for detecting and protecting personal information from electronic documents. However, due to the poor recognition rate of the OCR engine, personal information cannot be detected or false positives commonly occur. It also takes a long time to analyze a large amount of electronic documents. In this paper, we propose a method to improve the speed of image analysis of electronic documents, character recognition rate of the OCR engine, and detection rate of personal information by improving the existing method. The analysis speed was increased using the format recognition method while the analysis speed and character recognition rate of the OCR engine was improved by image correction. An algorithm for analyzing personal information from images was proposed to increase the reconnaissance rate of personal information. Through the experiments, 1755 image format recognition samples were analyzed in an average time of 0.24 seconds, which was 0.5 seconds higher than the conventional PAID system format recognition method, and the image recognition rate was 99%. The proposed method in this paper can be used in various fields such as public, telecommunications, finance, tourism, and security as a system to protect personal information in electronic documents.

• Clinical and Experimental Reproductive Medicine
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• v.30 no.3
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• pp.223-231
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• 2003

Objective: The aim of the present study was to evaluate the clinical efficiency of fluorescent in situ hybridization (FISH) in the prenatal diagnosis of chromosomal aneuploidy. Methods: We reviewed data of 268 cases to identify women undergoing genetic amniocentesis at cytogenetic laboratory, from January 2000 to December 2002. Amniotic fluid was submitted for both rapid FISH on uncultured interphase amniocytes using a commercially available DNA probe for chromosome 13, 18, 21, X, Y and standard karyotyping on cultured metaphase amniocytes. Results from FISH and full karyotype were compared. Results: There were 251 cases (84%) normal and 17 cases (16%) abnormal in FISH results. All 17 cases of trisomy 13, 18, 21 including two cases of mosaicism and sex chromosome aneuploidies which are detected by FISH were confirmed with conventional cytogenetics and there was no false positive result. Twenty two cases had karyotypically proven abnormalities that could not have been detected by the targeted FISH. Conclusion: Interphase FISH analysis of uncultured amniotic fluid cells has been shown to be an effective and reliable technique for rapid fetal aneuploidy screening during pregnancy as an adjunctive test to conventional cytogenetics.

• Korean Journal of Cognitive Science
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• v.25 no.4
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• pp.385-416
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• 2014

In this study, memory for emotional words was compared between extraverts and introverts, employing signal detection analysis to distinguish differences in discriminative memory and response bias. Subjects were presented with a study list of emotional words in an encoding session, followed by a recognition session. Effects of task difficulty were examined by varying the nature of the encoding task and the intervals between study and test. For an easy task, with a retention interval of 5 minutes (Study I), introverts exhibited better memory (i.e., higher d') than extraverts, particularly for low-frequency words, and response biases did not differ between these two groups. For a difficult task, with a one-month retention period (Study II), performance was poor overall, and only high-frequency words were remembered; also extraverts adopted a more liberal criterion for 'old' responses (i.e., more hits and more false alarms) for positive emotional-valence words. These results suggest that as task difficulty drives down performance, effects of internal control processes become more apparent, revealing differences in response biases for positive words between extraverts and introverts. These results show that extraversion can distort memory performance for words, depending on their emotional valence.

• Journal of Korea Multimedia Society
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• v.11 no.5
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• pp.610-622
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• 2008

Moving object segmentation is an essential technique for various video surveillance applications. The result of moving object segmentation often contains shadow regions caused by the color difference of shadow pixels. Hence, moving object segmentation is usually followed by a shadow elimination process to remove the false detection results. The common assumption adopted in previous works is that, under the illumination variation, the value of chromaticity components are preserved while the value of intensity component is changed. Hence, color transforms which separates luminance component and chromaticity component are usually utilized to remove shadow pixels. In this paper, various color spaces (YCbCr, HSI, normalized rgb, Yxy, Lab, c1c2c3) are examined to find the most appropriate color space for shadow elimination. So far, there have been some research efforts to compare the influence of various color spaces for shadow elimination. However, previous efforts are somewhat insufficient to compare the color distortions under illumination change in diverse color spaces, since they used a specific shadow elimination scheme or different thresholds for different color spaces. In this paper, to relieve the limitations of previous works, (1) the amount of gradients in shadow boundaries drawn to uniform colored regions are examined only for chromaticity components to compare the color distortion under illumination change and (2) the accuracy of background subtraction are analyzed via RoC curves to compare different color spaces without the problem of threshold level selection. Through experiments on real video sequences, YCbCr and normalized rgb color spaces showed good results for shadow elimination among various color spaces used for the experiments.