• Title/Summary/Keyword: FACT-L

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Parameter resetting in adult second language acquisition (성인의 제2 언어 습득에 있어서 매개변수 재고정)

  • Kim, Hak-Soo
    • English Language & Literature Teaching
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    • no.5
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    • pp.219-247
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    • 1999
  • The purpose of this paper is to examine how Korean learners of English reset the "prodrop" parameter of Korean into "non-prodrop" parameter of English in the process of English acquisition. An experiment was conducted to 45 Korean learners of English on the prodrop phenomenon, namely on the null referential or null nonreferential subject, and subject-verb agreement by way of grammatical judgment. The results of the experiment are as follows: First, L2 learners follow the parameter of L1, and then reset the parameter of L2 regardless of the parameter of L1 as their L2 abilities advance. Thus, this study provides further support for the hypothesis that universal grammar is available via L1. Second, the referential subject is, at first, easier to acquire than nonreferential subject, and the triggering fact for the switch from [+prodrop] to [-prodrop] was the use of nonreferential subjects. Third, 3rd person agreement has no connection with the acquisition of the prodrop parameter as a result of subject-verb agreement. Therefore, these results indicate that verb agreement is not a trigger for the recognition of the obligatory subject.

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Overexpression of a delayed early gene hlg1 of temperate mycobacteriophage L1 is lethal to both M. smegmatis and E. coli

  • Chattoraj, Partho;Ganguly, Tridib;Nandy, Ranjan Kumar;Sau, Subrata
    • BMB Reports
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    • v.41 no.5
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    • pp.363-368
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    • 2008
  • Two genes of temperate mycobacteriophage L5, namely, gp63 and gp64, were hypothesized to be toxic to M. smegmatis. An identical L5 gp64 ortholog (designated hlg1) was cloned from homoimmune mycobacteriophage L1 and characterized at length here. As expected, hlg1 affected the growth of M. smegmatis when overexpressed from a resident plasmid. HLG1 (the protein encoded by hlg1) in fact caused growth retardation of M. smegmatis and the region encompassing its 57-114 C-terminal amino acid residues was found indispensable for its growthretardation activity. Both nucleic acid and protein biosynthesis were severely impaired in M. smegmatis expressing HLG1. Interestingly, HLG1 also affected E. coli almost similarly. This putative delayed early lipoprotein did not participate in the lytic growth of L1.

Metabolic Engineering for Improved Fermentation of L-Arabinose

  • Ye, Suji;Kim, Jeong-won;Kim, Soo Rin
    • Journal of Microbiology and Biotechnology
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    • v.29 no.3
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    • pp.339-346
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    • 2019
  • L-Arabinose, a five carbon sugar, has not been considered as an important bioresource because most studies have focused on D-xylose, another type of five-carbon sugar that is prevalent as a monomeric structure of hemicellulose. In fact, L-arabinose is also an important monomer of hemicellulose, but its content is much more significant in pectin (3-22%, g/g pectin), which is considered an alternative biomass due to its low lignin content and mass production as juice-processing waste. This review presents native and engineered microorganisms that can ferment L-arabinose. Saccharomyces cerevisiae is highlighted as the most preferred engineering host for expressing a heterologous arabinose pathway for producing ethanol. Because metabolic engineering efforts have been limited so far, with this review as momentum, more attention to research is needed on the fermentation of L-arabinose as well as the utilization of pectin-rich biomass.

Current understanding of cancer-intrinsic PD-L1: regulation of expression and its protumoral activity

  • Yadollahi, Pedram;Jeon, You-Kyoung;Ng, Wooi Loon;Choi, Inhak
    • BMB Reports
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    • v.54 no.1
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    • pp.12-20
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    • 2021
  • In the last decade, we have witnessed an unprecedented clinical success in cancer immunotherapies targeting the programmed cell-death ligand 1 (PD-L1) and programmed cell-death 1 (PD-1) pathway. Besides the fact that PD-L1 plays a key role in immune regulation in tumor microenvironment, recently a plethora of reports has suggested a new perspective of non-immunological functions of PD-L1 in the regulation of cancer intrinsic activities including mesenchymal transition, glucose and lipid metabolism, stemness, and autophagy. Here we review the current understanding on the regulation of expression and intrinsic protumoral activity of cancer-intrinsic PD-L1.

The Analysis of Algorithm for L1/L2 Dual - Band GPS Receiver (L1/L2 듀얼 밴드 GPS 수신기의 상위 레벨 분석)

  • 김진복;송호준
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 1999.05a
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    • pp.78-81
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    • 1999
  • The position and time errors of a conventional L1-band GPS receiver (1575.42MHz) are known to be about 100 m and 70 ns, respectively. These errors are mainly due to the propagation delay of GPS satellite signals through ionosphere. Various L1/L2 dual-band GPS receivers are normally used to compensate for those position and time errors by detecting an accurate propagation delay. These receivers detect the propagation delay difference between the L1 and L2 signals based on the fact that the propagation delay through ionosphere is dependent on frequency and, from which, calculate an accurate propagation delay of the GPS signals through ionosphere. In this paper, we analyzed the architecture of a L1/L2 dual-band CPS receiver by high-level simulations with Synopsys's COSSAP Tool.

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MODULES OF QUOTIENTS OVER COMMUTATIVE RINGS

  • Lee, Jae-Gook;Rij, Seog-Hoon
    • Communications of the Korean Mathematical Society
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    • v.14 no.2
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    • pp.287-293
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    • 1999
  • In this paper, we give an affirmative answer to the question raised in [5]; whether L((P)) is principal or not. Using this fact, we try to give concrete form of module of quotient with respect to a torsion theory determined by L((P)).

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Miyachi's Theorem for the k-Hankel Transform on ℝd

  • Mohamed Amine Boubatra
    • Kyungpook Mathematical Journal
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    • v.63 no.3
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    • pp.425-435
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    • 2023
  • The classical Hardy Theorem on R states that a function f and its Fourier transform cannot be simultaneously very small; this fact was generalized by Miyachi in terms of L1 + L and log+-functions. In this paper, we consider the k-Hankel transform, which is a deformation of the Hankel transform by a parameter k > 0 arising from Dunkl's theory. We study Miyachi's theorem for the k-Hankel transform on ℝd.

GENERATING PAIRS FOR THE SPORADIC GROUP Ru

  • Darafsheh, M.R.;Ashrafi, A.R.
    • Journal of applied mathematics & informatics
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    • v.12 no.1_2
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    • pp.143-154
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    • 2003
  • A finite group G is called (l, m, n)-generated, if it is a quotient group of the triangle group T(l, m, n) = 〈$\chi$, y, z│$\chi$$\^$l/ = y$\^$m/ = z$^n$ = $\chi$yz = 1〉. In [19], the question of finding all triples (l, m, n) such that non-abelian finite simple group are (l, m, n)-generated was posed. In this paper we partially answer this question for the sporadic group Ru. In fact, we prove that if p, q and r are prime divisors of │Ru│, where p < q < r and$.$(p, q) $\neq$ (2, 3), then Ru is (p, q, r)-generated.

Update on Health-related Quality of Life in Colorectal Cancer Patients

  • Young-Seok Cho
    • Journal of Digestive Cancer Research
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    • v.3 no.2
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    • pp.70-75
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    • 2015
  • Along with the recent trend of improved survival in patients with colorectal cancer (CRC), health-related quality of life (HRQoL) has become a significant outcome measure and its improvement is an important goal. The most widely adopted CRC specific HRQoL questionnaires are the European Organization for Research and Treatment of Cancer Qualityof-Life Questionnaire (EORTC QLQ-CR38) and the Functional Assessment of Cancer Therapy (FACT-C). CRC survivors without serious comorbidity or recurrence experience only minor deficits of overall HRQoL when compared to the general population. However, disease recurrence, progression, and more specific limitations, including weight loss, reduction in energy, and psychosocial problems like psychological distress and depression, could result in lower HRQoL. To improve HRQoL, further research is required to develop appropriate health education regarding lifestyle changes and personalized intervention strategies for CRC survivors.

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THE SECONDARY UPSILON FUNCTION OF L-SPACE KNOTS IS A CONCAVE CONJUGATE

  • Masakazu Teragaito
    • Bulletin of the Korean Mathematical Society
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    • v.61 no.2
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    • pp.469-477
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    • 2024
  • For a knot in the 3-sphere, the Upsilon invariant is a piecewise linear function defined on the interval [0, 2]. It is known that this invariant of an L-space knot is the Legendre-Fenchel transform (or, convex conjugate) of a certain gap function derived from the Alexander polynomial. To recover an information lost in the Upsilon invariant, Kim and Livingston introduced the secondary Upsilon invariant. In this note, we prove that the secondary Upsilon invariant of an L-space knot is a concave conjugate of a restricted gap function. Also, a similar argument gives an alternative proof of the above fact that the Upsilon invariant of an L-space knot is a convex conjugate of a gap function.