• The Korean Journal of Nuclear Medicine Technology
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• v.28 no.1
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• pp.41-47
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• 2024

Purpose: ¹⁸F-FET, a radiopharmaceutical based on a Tyrosine amino acid derivative using the Sodium-Potassium Pump-independent Transporter (System L) for non-invasive evaluation of primary, recurrent, and metastatic brain tumors, exhibits distinct characteristics. Unlike the widely absorbed ¹⁸F-FDG in both tumor and normal brain tissues, ¹⁸F-FET demonstrates specific uptake only in tumor tissue while almost negligible uptake in normal brain tissue. This study aims to compare and evaluate the usefulness of ¹⁸F-FDG and ¹⁸F-FET Brain PET/CT quantitative analysis in brain tumor diagnosis. Materials and Methods: In 46 patients diagnosed with brain gliomas (High Grade: 34, Low Grade: 12), Brain PET/CT scans were performed at 40 minutes after ¹⁸F-FDG injection and at 20 minutes (early) and 80 minutes (delay) after ¹⁸F-FET injection. SUV_max and SUV_peak of tumor areas corresponding to MRI images were measured in each scan, and the SUV_max-to-SUV_peak ratio, an indicator of tumor prognosis, was calculated. Differences in SUV_max, SUV_peak, and SUV_max-to-SUV_peak ratio between ¹⁸F-FDG and ¹⁸F-FET early/delay scans were statistically verified using SPSS (ver.28) package program. Results: SUV_max values were 3.72±1.36 for ¹⁸F-FDG, 4.59±1.55 for ¹⁸F-FET early, and 4.12±1.36 for ¹⁸F-FET delay scans. The highest SUV_max was observed in ¹⁸F-FET early scans, particularly in HG tumors (4.85±1.44), showing a slightly more significant difference (P<0.0001). SUV_peak values were 3.33±1.13 for ¹⁸F-FDG, 3.04±1.11 for ¹⁸F-FET early, and 2.80±0.96 for ¹⁸F-FET delay scans. The highest SUV_peak was in ¹⁸F-FDG scans, while the lowest was in ¹⁸F-FET delay scans, with a more significant difference in HG tumors (P<0.001). SUV_max-to-SUV_peak ratio values were 1.11±0.09 for ¹⁸F-FDG, 1.54±0.22 for ¹⁸F-FET early, and 1.48±0.17 for ¹⁸F-FET delay scans. This ratio was higher in ¹⁸F-FET scans for both HG and LG tumors (P<0.0001), but there was no statistically significant difference between ¹⁸F-FET early and delay scans. Conclusion: This study confirms the usefulness of early and delay scans in ¹⁸F-FET Brain PET/CT examinations, particularly demonstrating the changes in objective quantitative metrics such as SUV_max, SUV_peak, and introducing the SUV_max-to-SUV_peak ratio as a new evaluation metric based on the degree of tumor malignancy. This is expected to further contributions to the quantitative analysis of Brain PET/CT images.

• Korean Journal of Poultry Science
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• v.30 no.2
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• pp.95-99
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• 2003

A total of 112 male and 1208 female Ross broiler breeders (30-wk-old) were used in this study to investigate whether a male to female (M/F) ratio of broiler breeder chickens may influence fertility and hatchability of hatching eggs. There were three treatments, each consisting of four pens with a size of 3.2 m ${\times}$ 6.4 m. Each pen housed approx. 100 females and 10 males to give the M/F ratio as follows: T1, 1/9; T2, 1/11; and T3, 1/13, respectively. The fertility of broiler breeder eggs ranged between 93 to 94％ at 30 wk of age. At 35 wk of age, breeder eggs from T3 tended to be less fertile (P>0.05) than those from T1 and T2. The low fertility observed in T3 at 35 wk of age further reduced to reach a statistical significance at 46 wk of age (P<0.05) when compared to those of T1 and T2. Hatchability of breeder eggs among treatments tended to follow a similar trend as shown in fertility, keeping hatchability of breeder eggs from T3 low when compared to the groups of T1 and T2. Our results indicated that the M/F ratio influenced fertility and consequently hatchability of breeder eggs. Furthermore, our study suggests that either 1/9 or 1/11 M/F ratio, but not 1/13 M/F ratio, seems suitable to sustain reproductive performance of broiler breeders throughout the laying periods.

• Korean Journal of Materials Research
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• v.17 no.7
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• pp.376-381
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• 2007

Fluorine-doped tin oxide (FTO) thin film was coated on aluminosilicate glass at $450^{\circ}C$ by spray pyrolysis method. In the range of 0-2.7 molar ratio of F/Sn, the variations of electrical conductivity and visible light transmission were investigated. At the F/Sn ratio of 1.765, the film showed the lowest electrical resistivity value of $3.0{\times}10^{-4}{\Omega}\;cm$, the highest carrier concentration of $2.404{\times}10^{21}/cm^3$, and about $8\;cm^2/V{\cdot}sec$ of electronic mobility. The FTO film showed a preferred orientation of (200) plane parallel to the substrate. X-ray photoelectron spectroscopy analysis results indicated that the contents of $Sn^{4+}-O$ bonding are the highest at 1.765 of F/Sn molar ratio.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.47 no.3
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• pp.151-156
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• 2002

The heritability of sink-source characters was estimated by regression coefficient between F$_2$ and F$_{5}$ in two crosses of IR 66738-118-1-2/Gayabyeo and the Ilpumbyeo/YR 15965 Acp 33. In order to get the some basic information for breeding of high yielding rice, genetic resources of new plant type with low tiller and heavy panicle were used. Most of the sink and source characters in Ilpumbyeo/YR 15965 Acp 33 cross showed high heritability over than 0.224. But the specific leaf area and sink-source ratio displayed low heritability being 0.009 and 0.013, respectively. Heritability of all sink and source characters in IR 66738-118-1-2/Gayabyeo cross ranged from 0.115 to 0.247. Correlation coefficient between yield and yield components in both combination were in the ranged between 0.001 and 0.247. But correlations among the yield components were not significant. Correlations between the yield and sink-source characters in both combinations were also highly significant. Particularly, correlation between the grain tiling ratio and most of the sink-source characters in IR 66738-118-1-2/Gayabyeo cross were not significant. In Ilpumbyeo/YR 15965 Acp 33 cross, correlations between grain filling ratio and source characters were positively significant. but sink characters (sink capacity and sink-source ratio, etc) were negatively significant.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2003.10a
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• pp.195-203
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• 2003

Spray and Mixing characteristics of the unlike impinging triplet injectors (F-O-F, O-F-O) were investigated with the variation of the momentum ratio of oxidizer to fuel. The spray pattern was measured using a backlit stroboscopic photography technique, and mixing efficiency was measured using a mechanical patternator. Kerosene/water were used as a propellant simulant. From the experimental results, it is found that a O-F-O type injector has a good atomization. And as the momentum ratio increases, the mixing efficiency decreases rapidly.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2006.05a
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• pp.680-685
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• 2006

This paper describes the aeroelastic stability test of the small-scaled 'Next-Generation Blade(NRSB)' with NRSH (Next-Generation Hub System) and HCTH hingeless hub system in hover and forward flight conditions. Excitation tests of rotor system installed in GSRTS(General Small-scale Rotor Test System) at KARI(Korea Aerospace Research Institute) were tarried out to get lead-lag damping ratio of blades with flexures as hub flexure. MBA(Moving Block Analysis) technique was used for the estimation of lead-lag damping ratio. First, NRSB-1F blades with HCTH hub system, Then NRSB-1F with NRSH hub system were tested. Second, NRSB-2F blades with NRSH hub system were tested. Tests were done on the ground and in the wind tunnel according to the test conditions of hover and forward flight, respectively. Non-rotating natural frequencies, non-rotating damping ratios and rotating natural frequencies were showed similar level fir each cases. Estimated damping ratios of NRSB-1F, NRSB-2F with HCTH and NRSH were above 0.5%, and damping ratio increased by collective pitch angle increasement. Furthermore damping ratios of NRSB-2F were higher than damping ratios of NRSB-1F in high pitch angle. It was confirmed that the blade design for noise reduction would give observable improvement in aeroelastic stability compared to paddle blade and NRSB-1F design.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.16 no.8 s.113
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• pp.848-856
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• 2006

This paper describes the aeroelastic stability test of the small-scaled 'Next-generation Blade(NRSB)' with NRSH (next-generation hub system) and HCTH hingeless hub system in hover and forward flight conditions. Excitation tests of rotor system installed in GSRTS (general small-scale rotor test system) at KARI (Korea Aerospace Research Institute) were carried out to get lead-lag damping ratio of blades with flexures as hub flexure. MBA(moving block analysis) technique was used for the estimation of lead-lag damping ratio. First, NRSB-1F blades with HCTH hub system, then NRSB- 1F with NRSH hub system were tested. Second, NRSB-2F blades with NRSH hub system were tested. Tests were done on the ground and in the wind tunnel according to the test conditions of hover and forward flight, respectively. Non-rotating natural frequencies, non-rotating damping ratios and rotating natural frequencies were showed similar level for each cases. Estimated damping ratios of NRSB-1F, NRSB-2F with HCTH and NRSH were above 0.5%, and damping ratio increased by collective pitch angle increasement. Furthermore damping ratios of NRSB-2F were higher than damping ratios of NRSB-1F in high Pitch angle. It was confirmed that the blade design for noise reduction would give observable improvement in aeroelastic stability compared to paddle blade and NRSB-1F design.

• Nuclear Medicine and Molecular Imaging
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• v.43 no.5
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• pp.369-385
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• 2009

In this paper, the authors intended to summarize briefly the features of lymphoma with regard to $^{18}F$-FDG PET for assessment of tumor response to therapy, to describe why assessment of treatment response should be performed, to review what method so far has been used in monitoring treatment response, to discuss what limitations of morphologic imaging criteria for assessing tumor response are, in compared with $^{18}F$-FDG PET, and to introduce recently proposed criteria for assessing tumor response in malignant lymphoma. And also the authors emphasize the need to understand the characteristics of diagnostic performance of $^{18}F$-FDG PET in several clinical settings in order to interpret $^{18}F$-FDG PET results appropriately, and to encourage the use of interval likelihood ratio to enhance clinical implications of test results which, in turns, allows referring physicians to understand the meaning of interpretation with easy. Until recently, treatment response has been assessed according to the morphologic criteria. Metabolic imaging with $^{18}F$-FDG PET was adopted to have important role for treatment assessment in IWC+PET criteria proposed recently by IHP. To accomplish this role, we should perform and interpret $^{18}F$-FDG PET according to IWC+PET criteria. It is important for referring physicians to understand the various limitations of $^{18}F$-FDG PET and pitfalls in PET interpretation, and to understand that clinical information are needed by nuclear medicine physicians to optimize the interpretation of $^{18}F$-FDG PET.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.29 no.1A
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• pp.19-30
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• 2009

The primary objective of the present study was to attempt to quantify the effect of the existing codes for CFT composite section on initial section flexural stiffness, based on the measured vibration frequency of CFT truss girders. The formulae for the initial flexural stiffness of the composite sections in the different codes are compared with the free vibration test results. The results of the free vibration test on the CFT truss girders are in good agreement with the analysis results when used in ACI formulae. The free vibration analysis of CFT truss girders for different f/L ratios was conducted to determine how the natural frequency of the CFT truss girder is affected by different f/L ratios. The presence of the f/L ratios in CFT truss girders alters its frequencies of vibration because of the global stiffness of the CFT girders. The frequency in horizontal modes decreases as the f/L ratio increases. However, the frequency in vertical modes increases as the f/L ratio increases.

• Journal of the Korean Society of Propulsion Engineers
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• v.3 no.3
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• pp.1-8
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• 1999

Mixing efficiency of the unlike Impinging split triplet injector(FOOF type) were measured to investigate the effect of the momentum ratio variation. $H_2$O/kerosene were used as a propellant simulant. The maximum mixing efficiency occured at the momentum ratio 1.5 (total mixture ratio 1.89). Calculated mixing efficiency of real propellant LOX/Kerosene showed similar trend but maximum efficiency of characteristic velocity occurs at the momentum ratio 2.0(total mixture ratio 2.17). Although there exist a little discrepancy between calculated mixing efficiency based on simulant cold test and hot fire test results, this calculated mixing efficiency can be used to predict hot fire mixing efficiency.