• Title/Summary/Keyword: F-51D

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A study of the plan dosimetic evaluation on the rectal cancer treatment (직장암 치료 시 치료계획에 따른 선량평가 연구)

  • Jeong, Hyun Hak;An, Beom Seok;Kim, Dae Il;Lee, Yang Hoon;Lee, Je hee
    • The Journal of Korean Society for Radiation Therapy
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    • v.28 no.2
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    • pp.171-178
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    • 2016
  • Purpose : In order to minimize the dose of femoral head as an appropriate treatment plan for rectal cancer radiation therapy, we compare and evaluate the usefulness of 3-field 3D conformal radiation therapy(below 3fCRT), which is a universal treatment method, and 5-field 3D conformal radiation therapy(below 5fCRT), and Volumetric Modulated Arc Therapy (VMAT). Materials and Methods : The 10 cases of rectal cancer that treated with 21EX were enrolled. Those cases were planned by Eclipse(Ver. 10.0.42, Varian, USA), PRO3(Progressive Resolution Optimizer 10.0.28) and AAA(Anisotropic Analytic Algorithm Ver. 10.0.28). 3fCRT and 5fCRT plan has $0^{\circ}$, $270^{\circ}$, $90^{\circ}$ and $0^{\circ}$, $95^{\circ}$, $45^{\circ}$, $315^{\circ}$, $265^{\circ}$ gantry angle, respectively. VMAT plan parameters consisted of 15MV coplanar $360^{\circ}$ 1 arac. Treatment prescription was employed delivering 54Gy to recum in 30 fractions. To minimize the dose difference that shows up randomly on optimizing, VMAT plans were optimized and calculated twice, and normalized to the target V100%=95%. The indexes of evaluation are D of Both femoral head and aceta fossa, total MU, H.I.(Homogeneity index) and C.I.(Conformity index) of the PTV. All VMAT plans were verified by gamma test with portal dosimetry using EPID. Results : D of Rt. femoral head was 53.08 Gy, 50.27 Gy, and 30.92 Gy, respectively, in the order of 3fCRT, 5fCRT, and VMAT treatment plan. Likewise, Lt. Femoral head showed average 53.68 Gy, 51.01 Gy and 29.23 Gy in the same order. D of Rt. aceta fossa was 54.86 Gy, 52.40 Gy, 30.37 Gy, respectively, in the order of 3fCRT, 5fCRT, and VMAT treatment plan. Likewise, Lt. Femoral head showed average 53.68 Gy, 51.01 Gy and 29.23 Gy in the same order. The maximum dose of both femoral head and aceta fossa was higher in the order of 3fCRT, 5fCRT, and VMAT treatment plan. C.I. showed the lowest VMAT treatment plan with an average of 1.64, 1.48, and 0.99 in the order of 3fCRT, 5fCRT, and VMAT treatment plan. There was no significant difference on H.I. of the PTV among three plans. Total MU showed that the VMAT treatment plan used 124.4MU and 299MU more than the 3fCRT and 5fCRT treatment plan, respectively. IMRT verification gamma test results for the VMAT plan passed over 90.0% at 2mm/2%. Conclusion : In rectal cancer treatment, the VMAT plan was shown to be advantageous in most of the evaluation indexes compared to the 3D plan, and the dose of the femoral head was greatly reduced. However, because of practical limitations there may be a case where it is difficult to select a VMAT treatment plan. 5fCRT has the advantage of reducing the dose of the femoral head as compared to the existing 3fCRT, without regard to additional problems. Therefore, not only would it extend survival time but the quality of life in general, if hospitals improved radiation therapy efficiency by selecting the treatment plan in accordance with the hospital's situation.

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Refractive index control of F-doped SiOC : H thin films by addition fluorine (Fluorine 첨가에 의한 F-doped SiOC : H 박막의 저 굴절률 특성)

  • Yoon, S.G.;Kang, S.M.;Jung, W.S.;Park, W.J.;Yoon, D.H.
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.17 no.2
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    • pp.47-51
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    • 2007
  • F-doped SiOC : H thin films with low refractive index were deposited on Si wafer and glass substrate by plasma enhanced chemical vapor deposition (PECVD) as a function of rf powers, substrate temperatures, gas rates and their composition flow ratios ($SiH_4,\;CF_4$ and $N_2O$). The refractive index of the F-doped SiOC : H film continuously decreased with increasing deposition temperature and rf power. As $N_2O$ gas flow rate decreased, the refractive index of the deposited films decreased down to 1.3778, reaching a minimum value at rf power of 180W and $100^{\circ}C$ without $N_2O$ gas. The fluorine content of F-doped SiOC : H film increased from 1.9 at% to 2.4 at% as the rf power was increased from 60 W to 180 W, which results in the decrease of refractive index.

Analysis of Heat Loss Due to Time Dependent Aging of Insulation Applied to Office Building (업무용 건축물에 적용된 단열재의 경년열화에 따른 열손실량 분석)

  • Lee, Do-Hyung;Nah, Hwan-Seon
    • Journal of the Korean Solar Energy Society
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    • v.37 no.5
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    • pp.65-75
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    • 2017
  • In this study, the change of heat loss due to the degree of deterioration of the XPS insulation in KEPCO's office buildings is analyzed. The acceleration aging test of the XPS insulation was carried out according to the test method A of KS M ISO 11561: 2009. The performance of the insulation was analyzed by applying it to the three - dimensional steady state heat transfer analysis program. The acceleration aging test of the XPS insulation, show that the thermal resistance performance decreased by 1.44% at the A regional headquarters, 0.85% at the B regional headquarters, 6.41% at the C branch office, 7.76% at the D regional headquarters, 8.51% at the E branch office, and by 8.54% at the F branch office respectively. Using simulation, we determined that the thermal resistance value of E branch office decreased by 8.04%, while its heat loss increased by 8.52%. At A regional headquarters, the thermal resistance decreased by 1.38%, and the heat loss increased by 1.51%. At D regional headquarters, these value are 6.82% and 7.17%, respectively.

Micro-computed tomography evaluation of general trends in aligner thickness and gap width after thermoforming procedures involving six commercial clear aligners: An in vitro study

  • Palone, Mario;Longo, Mattia;Arveda, Niki;Nacucchi, Michele;De Pascalis, Fabio;Spedicato, Giorgio Alfredo;Siciliani, Giuseppe;Lombardo, Luca
    • The korean journal of orthodontics
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    • v.51 no.2
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    • pp.135-141
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    • 2021
  • Objective: To assess the effects of thermoforming on aligner thickness and gap width in six aligner systems with the same nominal thickness. Methods: Six passive upper aligners of different brands were adapted to a single printed cast. Each sample was evaluated with high-resolution micro-computed tomography. To investigate aligner thickness and gap width, two-dimensional (2D) analysis was conducted assessing the effects of the following variables: tooth type (central incisor, canine, and first molar), 2D reference points, and aligner type. Data were analyzed and compared using analysis of variance and Tukey's post-hoc tests (p < 0.05). Results: Tooth type, dental region, and aligner type affected both the gap width and aligner thickness. The aligner thickness remained moderately stable across the arch only in the F22. Conclusions: All thermoformed samples displayed smaller aligner thickness and gap width at anterior teeth and both gingival and coronal centers than at posterior teeth and occlusal surfaces.

Dynamic Test of Structural Models Using $4m{\times}4m$ Shaking Table ($4m{\times}4m$ 진동대를 이용한 구조모델의 동적실험)

  • 이한선;우성우;김병현
    • Journal of the Earthquake Engineering Society of Korea
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    • v.1 no.1
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    • pp.51-56
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    • 1997
  • The objective of this study is to review the current state of earthquake simulation tecniques using the shaking table and check the reliability. One degree-of-freedom(d.o.f) and three d.o.f aluminium shear models were used and $4m{\times}4m$ 6 d.o.f shaking table was excitated in one horizontal direction to simulate 1940 El centro earthquake accelerogram (NS component). When the actual acceleration history of shaking table is compared to the desired one, it can be found that the overall histories are very similar, but that the lower frequency range (0~2 Hz) of the actual excitation has generally lower amplitude than that of the desired in Fourier transform amplitude. Free vibration and white noise tests have shown almost the some values for natural frequencies, but shown quite different values for damping rations, that is, 1.37% in case of free vibration test vs 14.76 % in case of white noise test. The time histories of story shear driff show the globally linear elastic behaviors. But the elliptical shape of the histories with one of the axis being the stiffness of the story implies the effect of viscous damping.

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Kinetic Analysis of Isothermal Pyrolysis of Korean Refuse Plastic Fuel for Application to Circulating Fluidized Bed Boiler (순환유동층 적용을 위한 국내 폐플라스틱 고형연료의 등온 열분해 분석)

  • Park, Kyoung-Il;Kim, Dong-Won;Lee, Tae-Hee;Lee, Jong-Min
    • Korean Chemical Engineering Research
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    • v.51 no.6
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    • pp.692-699
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    • 2013
  • In this study, isothermal (350, 375, 400, 425, 450, 500, $850^{\circ}C$) experiments were carried out using a custom-made thermobalance to analyze the thermal decomposition properties of refuse plastic fuel (RPF), which is to be used as a cofiring fuel with a sub-bituminous coal at commercial circulating fluidized bed (CFB) boiler in Korea. In isothermal pyrolysis results, no change in the reaction model was observed in the temperature range of $375{\sim}450^{\circ}C$ and it was revealed that the first order chemical reaction (F1) is the most suitable among 12 reaction models. The activation energy shows similar results irrespective of application of reaction model in that the activation energy was 39.44 kcal/mol and 36.96 kcal/mol when using Arrhenius equation and iso-conversional method ($0.5{\leq}X{\leq}0.9$) respectively. Mean-while, the devolatilization time ($t_{dev}$) according to particle size (d) of RPF could be expressed as $t_{dev}=10.38d^{2.88}$ at $850^{\circ}C$, operation temperature of CFB and for even distribution and oxidation of RPF in CFB boiler, we found that the relationship of average dispersion distance (x) and particle size was $x{\leq}1.58d^{1.44}$.

Electrical Properties of (Ba,Ca)(Ti,Zr)O3 Ceramics for Bimorph-type Piezoelectric Actuator

  • Shin, Sang-Hoon;Yoo, Ju-Hyun
    • Transactions on Electrical and Electronic Materials
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    • v.15 no.4
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    • pp.226-229
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    • 2014
  • In this study, lead-free $(Ba_{0.85}Ca_{0.15})(Ti_{1-x}Zr_x)O_3$ ceramics and a bimorph-type piezoelectric actuator were fabricated using the normal oxide-mixed sintering method, and their dielectric properties, microstructure, and displacement properties were investigated. From the results of X-ray diffraction, the pattern of the specimen has a pure perovskite structure. In addition, no secondary impurity phases were found. The excellent piezoelectric coefficient of $d_{33}=454pC/N$, the electromechanical coupling factor $k_p=0.51$, the dielectric constant ${\varepsilon}_r=3,657$, the mechanical quality factor $Q_m=239$, and $T_c$(Tetragonal-Cubic) =$90^{\circ}C$ were shown at x= 0.085. ${\Delta}k_p/k_p20^{\circ}C$ and ${\Delta}f_r/f_r20^{\circ}C$ showed the maximum value of -0.255 and 0.111 at $-20^{\circ}C$ and $80^{\circ}C$, respectively. The maximum total-displacement was $60{\mu}m$ under the input voltage of 50 V. As a result, it is considered that lead-free $(Ba_{0.85}Ca_{0.15})(Ti_{1-x}Zr_x)O_3$ ceramics is a promising candidate for piezoelectric actuator application for x= 0.085.

Constituents of Paulownia tomentosa Stem(III): The Crystal Structure of Methyl 5-Hydroxy-dinaphtho[1,2-2',3]furan-7,12-dione-6-carboxylate

  • Park, Il-Yeong;Kim, Bak-Kwang;Kim, Yang-Bae
    • Archives of Pharmacal Research
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    • v.15 no.1
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    • pp.52-57
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    • 1992
  • The molecular structure of a natural compound was determined by single crystal X-ray diffraction analysis. The compound was isolated by methanol extraction and repeated chromatography from the stem of Paulownia tomentosa. Yellow prismatic crystals of the compound, which were recrystallized from tetrahydrofuran, are triclinic, with a = 7.310 (6), b = 10.753(6), c = 11.586(5) ${\AA}.\;\alpha= 93.30(6),\;\beta=105.62(10),\;\gamma=109.49(7)^\circ,\;D_x=1.514,\;D_m=1.51 g/cm^3$, space group P1 and Z = 2. The structure was solved by direct method, and refined by least-squares procedure to the final R-value of 0.032 for 1271 independent reflections $(F\le3\sigma{(F))}$. The compound is one of new furanquinone analogue. The molecule has a nearly planar conformation with an intramolecular hydrogen bond. In the crystal, the planar molecules are arranged as a prallel sheet-like pattern, and these stackings are stabilized by the O-H...O type intermolecular hydrogen bonds. The other intermolecular contacts appear to be the normal van der Waals interactions.

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Immunohistochemical Prognostic Factors in Soft Tissue Sarcoma (연부조직 육종에서 면역조직화학적 예후인자)

  • Choi, Kyung-Un;Kim, Jeung-Il;Moon, Nam-Hoon
    • The Journal of the Korean bone and joint tumor society
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    • v.14 no.2
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    • pp.106-118
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    • 2008
  • Purpose: Disturbed cell cycle regulatory proteins are key events underlying the development and/or progression of human malignancies. The aim of this study is to evaluate the protein expression status involved in G1/S cell cycle in human soft tissue sarcoma. Materials and Methods: We simultaneously evaluated the expression of Cyclin D1, Cyclin E, CDK4, CDK2, p16, p27, Rb, E2F1, p53 and Ki-67 by immunohistochemistry in 43 cases of soft tissue sarcoma Results: The Cyclin D1, Cyclin E, CDK4, CDK2, E2F1, and p53 were expressed in 25 (58.1%), 18 (41.9%), 13 (30.2%), 33 (76.7%), 20 (46.5%), and 18 cases (41.9%). The p16, p27, and Rb expressions were decreased in 26 (60.5%), 22 (51.2%) and 19 cases (44.2%). All of the cases showed alterations of more than one out of the above proteins. The increased Cyclin E expression and Ki-67 labeling index (LI) were significantly associated with histologic grade. The Cyclin E and E2F-1 expressions were increased in relapsed cases and the CDK4 expression was increased in cases of metastasis. Conclusion: Alterations of G1/S cell cycle regulatory proteins may play an important role in the tumoriogensis of soft tissue sarcomas. Our results suggest that increased expressions of Cyclin E, E2F1, and CDK4 were associated with tumor relapse or metastasis and could be considered as parameters of prognosis of soft tissue sarcoma.

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First Report of Root Rot of Dendropanax trifidus Caused by Fusarium oxysporum in Korea (Fusarium oxysporum에 의한 황칠나무 묘목 뿌리썩음병 발생 보고)

  • Hyerin Ma;Sungyu Choi;Hyunkyu Sang;Hyun-Jun Kim
    • The Korean Journal of Mycology
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    • v.51 no.1
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    • pp.51-56
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    • 2023
  • Dendropanax trifidus belonging to the family Araliaceae, is a warm-temperate evergreen tree distributed in Jeju Island, Bogil Island, Geomun Island, Geoje Island, Wando, and Haenam in Korea. In June 2021, a root rot disease in which branches of Dendropanax trifidus seedlings turned brown and shrunk was discovered at the seedling cultivation facility in Naju-si, Republic of Korea. To identify the root rot fungus, three strains were isolated from the diseased tissues of seedlings and their mycological characteristics were investigated on potato dextrose agar. In addition, a molecular phylogenetic analysis was performed using sequences of the internal transcribed spacer (ITS) region and translation elongation factor 1-α (EF1-α) gene. The fungus was identified as Fusarium oxysporum. For pathogenicity test, the roots of seedlings were immersed in the conidia suspension of the strains and planted. After 20 days inoculation, root rot and browning symptoms were confirmed in the inoculated plants. This is the first report of F. oxysporum on D. trifidus in Korea.