• 제목/요약/키워드: Exudation

검색결과 92건 처리시간 0.029초

흰쥐의 Carrageenin 유발 늑막염과 Croton oil 유발 육아종양에 미치는 Cyclobuxine D의 영향 (Effects of Cyclobuxine D on Carrageenin-induced Pleurisy and Croton Oil-induced Granuloma Pouch in Rats)

  • 이종화;박영현;조병헌;김유재;김종배;김정목;김천숙;차영덕;김영석
    • 대한약리학회지
    • /
    • 제23권2호
    • /
    • pp.151-157
    • /
    • 1987
  • Steroidal alkaloid인 cyclobuxine D의 carrageenin으로 유발한 늑막염과 croton oil로 유발한 육아종양에 대한 영향을 관찰하고 그 작용을 aspirin, dexamethasone과 hydrocortisone의 작용과 비교하였다. Carrageenin으로 유발한 늑막염에서 혈장 삼출정도는 pontamine sky blue을 정맥으로 투여하여 20분 동안 늑막염 삼출물로 삼출되어 나오는 양으로 측정하였다. Cyclobuxine D는 용량적으로 삼출물의 양과 20분 동안 삼출되는 pontamine sky blue의 양을 감소시켰다. Cyclooxygenase 억제제인 aspirin과 phospholipase $A_2$를 억제하여 결과적으로 cyclooxygenase와 lipoxygenase의 생성물을 차단하는 dexamethasone은 현저하게 carrageenin으로 나타나는 염증현상을 억제하였다. Cyclobuxine D는 croton oil로 유발한 육아종양에서 종양 부위에 직접 투여하거나 근육내로 투여해도 pouch내 염증물 양과 pouch wall의 무게를 현저하게 억제하였다. Dexamethasone과 hydrocortisone은 육아종양의 형성을 현저히 억제하였으며 , dexamethasone은 근육내로 투여 하였을 때 육아종양 형성을 완전히 억제하였다. 이상의 결과에서 나타난 cyclobuxine D의 항염증 작용은 prostaglandins의 생성억제 또는 polymorphonuclear cell (PMN)의 유주 억제와 밀접한 관련이 있을 것으로 사려된다.

  • PDF

산약(山藥)의 품질인증(品質認證) 방안(方案) (Quilitative certificational plan of shanyao)

  • 조은환;노성수;길기정;서부일;서영배
    • 혜화의학회지
    • /
    • 제13권2호
    • /
    • pp.187-196
    • /
    • 2004
  • Now many sustitution and false articles is used in korea instead of shanyao. To use shanyao correctly, we will make a quilitative certificational plan of shanyao to investigate all of lieraturea, records and documents. And we could reach conclusions as folloews. 1) Source About a source of shanyao, though korea and china has a each other source, we think there is no problem in use of both. 2) Process In our country producing shanyao as medical use is a 'duanma', we can divide into peeling and non-peeling, drying at bulks and at briquets, steaming shanyao and fresh shanyao. Regardless of existence for peeling and steaming, a distributing shanyao is received a proper judgment. Like this result was expressed by insufficiency of standards about medical components or indicating components. We detected a reminding S02 more than 10 ppm. And this expresses that there ia a problum at a drying method. To suggest proper processing methods, a standard of quility will have to be made which the existence of peeling, difference of quility between 'changma' and 'duanma', drying method and exudation test with cutted thickness are adaptable. Besides, 'maoshanyao' and 'guangshanyao' of china is processed by various methods which decrease a medical effect such as too much soaking shanyao in water, steaming with a sulfur, too much peeling, So we must process shanyao like the next methods. (1) When harvesting, dig deeply not to cut off roots. (2) Not to peel, wash shanyao in a washing machine. (3) Dry to 50-60% degree at sunny place or drying machine. (4) To be easy for drying and exudation, cut off a thick piece with 5 mm (5) Dry perfectly at ding machine. 3) Quality3) Quality (1) Functional standards It is not Proper that 'guangshanyao' is used in china because it has a problem with quility on process of working, If they did not soak shanyao in water or heat with steam, it is the real situation that they cannot cutt off shanyao evenly. In conclusion, shanyao must be heavy, powdery with a perfectly non-peeling surface, section surface is yellow-white color, unequal and has no holes. (2) Physicochemical standards It is the real situation that we can not distinguish into quility of shanyao with established test because various workings which decrease medical effects is used. Therefore we suggest a testing standard of S02 which is used in bleaching. And testing standards relatived with decrease of medical effects must be established at once. It must that Dry on loss is less than 14.0%, content of ash is less than 6.0%. Content of acid-nonsoluble ash is less than 0.5%. Contens of heavy metal has to detect less than 30 ppm and there is no reminding agricultural medince.

  • PDF

接觸性皮膚炎의 外治法에 關한 文獻的 考察 (A Literature study on the external therapy of contact dermatitis.)

  • 전재홍;김현아;강윤호
    • 한방안이비인후피부과학회지
    • /
    • 제11권1호
    • /
    • pp.197-218
    • /
    • 1998
  • In this study, I invastigate about oriental medical drug, dosage form and directions in external therapy of contact dermatitis. and after study on relationship oriental medical drug, dosage form and directions with cause, symptom and differentiation of symptom and sign. The results are as follows; 1. Most frequently used oriental medical drug is until qing(淸) dynasty Eriocheir sinensis H. Milne-Edwards(蟹), Salix babylonica L.(柳葉), Natrii sulfas(芒硝), Allium macrostemon Bge.(해), Nelumbo nucifera Gaertn.(荷葉), nowadays in Korea and China Phellodendron amurense Rupr.(黃柏), Gypsum(石膏), Rheum palmatum L.(大黃), Baphicacanthus cusia Bremek(靑黛), Talcum(滑石). 2. In the frequency of dosage form, until qing(淸) dynasty powder 1case, liquor 49cases, liquer and solid mixture 58cases, nowadays Korea and China powder 16cases, liquor 96cases, liquer and solid mixture 59cases. 3. Most frequently used directions of dosage is thinly attaching method(薄貼法), attaching method(敷貼法), furnigating and cleansing method(熏洗法), cleansing method(洗傷法), wet dressing method(濕敷法), spreading powder method(撲粉法), plaster method(途차法), rubbing skin method(摩擦法) 4. In the external therapy of contact dermatitis, oriental medical drug's usage is based on stage of contact dermatitis In acute stage, most frequently used drug is heat and damp remove drug(淸熱燥濕藥), nature of drug(藥性) is bitter taste and cold charactor(苦寒), In chronic stage, most frequently used drug is nourishing the blood drug(養血藥), promoting blood circulation drug(活血藥). 5. The dosage form of drug is based on symptom. In acute stage, when papules and vesicles, or erosion and exudation is the main symptom of skin, liquor or powder is used, when erosion and crust is the main symptom of skin, plaster is used. In chronic stage, plaster is used. 6. In the directions of dosage is based on dosage form of drug and symptom. In acute stage, when papules and vesicles is the main symptom of skin, fumigating and cleansing method, cleansing method, plaster method is used, when erosion, vesicles and exudation the main symptom of skill, cleansing method, wet dressing method, spreading powder method, attaching method, spreading powder method is used, when crust is the main symptom of skin, plaster method is used. In chronic stage, plaster method, rubbing skin method is used.

  • PDF

고로슬래그 미분말과 아라미드 섬유를 이용한 보강그라우트재 개발 (Development of Reinforcement Grout Materials Using Blast Furnace Slag Powder and Aramid Fiber)

  • 서혁;박경호;김찬정;김호철;김대현
    • 한국지반신소재학회논문집
    • /
    • 제18권1호
    • /
    • pp.67-77
    • /
    • 2019
  • 그라우팅 공법은 연약지반의 보강과 방수 및 지하수위저하 또는 상승과 진동으로 인한 침하 및 부등침하로 손상된 구조물의 지지력을 높이고 차수를 목적으로 하는데 사용된다. 본 연구는 아라미드 섬유를 이용하여 그라우트재료의 압축강도를 향상시키고, 고로슬래그 미분말을 이용하여 높은 강도의 지반개량공법을 개발하는데 있다. 따라서 본 연구에서는 시멘트와 고로슬래그미 분말의 비는 100:0, 70:30, 40:60%로 고치환(50%이상)까지 확인하고, 아라미드 혼입률은 시멘트와 고로슬래그 중량의 0, 0.5, 1.0%로 증가시켜 첨가하였으며, 표면의 유제처리 비율을 0.7과 1.2%로 샌드겔을 성형하여 일축압축시험을 수행하였다. 환경성 평가는 중금속용출시험과 pH 측정을 수행하였다. 실험결과 아라미드 섬유 1%첨가 시 일축압축강도는 약 1.3배 정도 강도가 증가하였고, 6가크롬은 고로슬래그 미분말이 30% 증가할수록 중금속 용출은 약 50% 감소하였으나, pH용출시험결과, 고로슬래그 미분말이 30% 증가할수록 pH는 약 0.5 증가하는 경향을 나타났다. 향후 pH에 대한 부분은 보완이 필요할 것으로 판단된다.

Isolation and Identification of Fusicoccum Species from Quercus dentata

  • Kim, Ki Woo;Kim, Pan-Gi;Lee, Myung-Bo
    • 한국산림과학회지
    • /
    • 제96권5호
    • /
    • pp.515-519
    • /
    • 2007
  • An imperfect fungus Fusiococcum species was isolated from Quercus dentata. A naturally infected Daimyo oak tree was collected and showed elongate wounds on the stem. The fungal cultures were initially white and cottony, and later turned dark gray. Numerous solitary pycnidia were developed on the medium surface, and typically spherical. Yellowish conidial masses were exuded from pycnidia on the culture plates. Conidial masses were swollen and measured as approximately 100 to $300{\mu}m$ in length. It appeared that conidia were usually held together in globose to oval drops. Conidia were hyaline, single-celled (nonseptate), ellipsoid to fusoid, and measured as approximately $8.0{\times}2.7{\mu}m$. Based on these cultural and morphological characteristics, the fungal isolate was identified as a species of Fusicoccum Corda. To preserve and examine fungal spores exuded from pycnidia on the medium surface, a vapor fixation procedure for scanning electron microscopy was employed in this study. The specimens were exposed to the vapor of 2% (v/v) glutaraldehyde and 2% (w/v) osmium tetroxide each for 2 h. With the vapor fixation we obtained excellent retention of conidial masses in this study. The simple and versatile procedure for demonstrating fungal spores and their exudation from fruiting bodies would facilitate characterization of diverse pathological and environmental isolates as they are in native environments.

구개근 절제술을 이용한 상악 제일 대구치의 치료 (Palatal root resection of compromised maxillary first molars)

  • 정성념
    • Journal of Periodontal and Implant Science
    • /
    • 제39권3호
    • /
    • pp.375-381
    • /
    • 2009
  • Purpose: Root resection can be a valuable procedure when the tooth in question has a high strategic value. The prognosis of root resection has been well documented in previous studies, but the results focused on the palatal root resection have not been discussed in depth. I represent here the short term effectiveness of palatal root resection of maxillary first molars. Methods: Palatal root resection was performed on maxillary first molars of three patients. All the palatal roots were floating state on the radiographic finding and showed full probing depth and purulent exudation at initial examination. Reduction of palatal cusp and occlusal table was performed concomitantly. Endodontic therapy was completed after root resection. Results: Compromised maxillary first molars were treated successfully by palatal root resection in 3 cases. The mobility of resected tooth was decreased a little bit. The probing pocket depth of remaining buccal roots was not increased compared to initial depth. All the patients satisfied with comfort and cost effective results and the fact they could save their natural teeth. Conclusions: Within the above results, palatal root resection is an effective procedure treating compromised maxillary first molar showing advanced palatal bone loss to root apex with or without pulp involvement when proper case selection is performed.

Yield enhancement of matrix precursor in short carbon fiber reinforced randomly oriented carbon/carbon composite

  • Raunija, Thakur Sudesh Kumar;Sharma, Sharad Chandra;Verma, Anil
    • Carbon letters
    • /
    • 제19권
    • /
    • pp.57-65
    • /
    • 2016
  • Isroaniso matrix precursor synthesized from commercially available petroleum pitch was stabilized in air. The influence of oxygen mass gain during stabilization on the yield of matrix precursor was studied. Additionally, the influence of pressure on the yield of the stabilized matrix precursor in a real system was studied. The fourier transform infrared spectrometry (FTIR), thermogravimetric analysis (TGA), yield, yield rate, and yield impact were used to check the effect of stabilization and pressure on the yield of the matrix precursor and the end properties of the composite thereafter. The results showed that the yield increased with stabilization duration up to 20 h whereas it decreased for stabilization duration beyond 20 h. Further results showed that the stabilized matrix precursor for a duration of 5 h could withstand almost two-fold greater hot-pressing pressure without resulting in exudation as compared to that of a 1 h stabilized matrix precursor. The enhanced hot-pressing pressure significantly improved the yield of the matrix precursor. As a consequence, the densification and mechanical properties were increased significantly. Further, the matrix precursor stabilized for a duration of 20 h or more failed to provide proper and uniform binding of the reinforcement.

도라지의 Ca.Mg.K.Na.P와 이들의 수침(水浸)과 Boiling에 따른 변화(變化) (Study on the Changes in Ca.Mg.K.Na and P Contents of the Platycodon Graucum Nakai by Water Immersion and Boiling)

  • 이월형;이만정
    • 한국식품영양과학회지
    • /
    • 제3권1호
    • /
    • pp.35-41
    • /
    • 1974
  • The experiment attempted to detect the loss of mineral substances in the crude herb, especially for the Platycodon graucum Nakai after removal of its acrid flavor. The results obtained are summarized as follows: 1. The quantity of the mineral substance was K Ca P Mg and Na in orders. The above substances were more prevalent in the part of the plant above the ground than the plant below the ground, however Na remained the same in both parts of the plant. 2. As a result of water immersion, in order to clear away the acrid flavor, the one day exudate showed that K was highest in amount and in the others there was no significant difference. There was a slight increase, however, in the amount of Ca K Mg P and Na because of exudation on the 3rd and 5 th days. 3. The amount of the exudate was increased by boiling rather than simple water immersion, but the amount of Ca was decreased.

  • PDF

Low Molecular Weight Organic Acids in Brassica pekinensis Rupr. and Growing soil Influenced by Simulated Nitrate Deposition

  • Xie, Wen-Ming;Liu, Xing-Quan;Ko, Kwang-Yong;Lee, Kyu-Seung
    • 한국환경농학회지
    • /
    • 제27권3호
    • /
    • pp.279-284
    • /
    • 2008
  • We investigated whether carboxylate exudation of Brassica pekinensis Rupr. was affected by nitrate deposition from simulated acid rain. A gas chromatographic (GC) analysis was employed for the determination of low molecular weight organic acids (LOA) in rhizosphere soils, bulk soil, roots and leaves of Brassica pekinensis Rupr.. Rhizosphere soils were collected after 8 weeks of plant growth by first removing the bulk soil from the root system and then by mechanical move off the rhizosphere soil that adhered to the root surface with soft brush. Soil and plant materials were simultaneously extracted with the mixture of methanol and sulfuric acid (100:7, v/v). Seven organic acids, oxalic, malonic, fumaric, succinic, maleic, L-malic and citric acid were identified and quantified by GC equipped with FID. Oxalic, L-malic, and citric acids were found in both the bulk and rhizosphere soils, while most LOAs were not detected in the control treatment. On the contrary, except maleic acid, all other organic acids were detected in the leaves and roots of cabbages treated with nitrate deposition.

피부화상에 의한 피부 및 간의 조직학적 변화에 관한 연구 (A study on Histologically Change of the Skin and Liver in Skin Burn)

  • 김한수;김상수;김용권
    • 대한물리치료과학회지
    • /
    • 제8권1호
    • /
    • pp.923-934
    • /
    • 2001
  • In order to investigate a pathogenesis of liver damage induced by skin burn, thermal injury was induced by scald burn on entirely dorsal surface in rats (total body surface area 30%) except for inhalated injury. At 5 and 24 h after scald bum, biochemical assay and morphological changes in skin tissue, serum and liver tissue were examined. The effects of bum injury on the levels of glutathione, lipid peroxide and on the activities of oxygen free radical generating and scavenging enzymes have been determined in association with observing of histologic and ultrastructural changes, measuring the protein concentration in plasma, and counting the number of intravascular polymorphonuclear leukocytes. The activity of xanthine oxidase, an enzyme of oxygen free radical generating system. was elevated (p<0.01) in serum, but not in skin and in liver tissue. Futhermore, thermal injury decreased not only the protein concentration in plasma but also the number of leukocytes, that indicates induction of edema formation with protein exudation and inflammation by neutrophil infiltration into the internal organs. These data suggest that acute dermal scald burn injury leads to liver damage, that is related to elevation of xanthine oxidase activity in serum. Xanthine oxidase may be a key role in the pathogenesis of liver damage induced by skin burn.

  • PDF