• Title/Summary/Keyword: Experimental Model

Search Result 19,149, Processing Time 0.051 seconds

Wound Healing Effect of Low Molecular PDRN on Experimental Surgical Excision Rat Model (저분자화된 Polydeoxynucleotide (PDRN)의 흰쥐에 대한 외과적 창상 치유 효과)

  • Yun, Jong-Kuk;Yoon, Hye-Eun;Park, Jeong-Kyu;Kim, Mi Ryeo;Kim, Dae-Ik
    • Journal of the Society of Cosmetic Scientists of Korea
    • /
    • v.41 no.4
    • /
    • pp.401-411
    • /
    • 2015
  • This study was performed to investigate the wound healing effect of skin regeneration cosmetics utilizing low molecular weight Polydeoxynucleotide (PDRN). High purity PDRN was prepared from salmon testes poly-deoxy-ribonucleotide through protein and toxin removal process and molecular weight reduction. In order to evaluate the wound healing effect of PDRN in SD rats, 4 sites of dorsal skin of each animal were excised by using biopsy punch and $500{\mu}L$ of test solution was topically applied once daily for 4 weeks. The tissue changes were observed for every week during the application periods. After applying the PDRN to the wound, the skin was cut flower and contraction of the wounds more quickly, and the coating of PDRN in the wound area was reduced significantly as compared to the positive control group $Fucidin^{(R)}$ applied. The microscopic observation of stained tissue showed that a positive control was most rapid in re-epithelialization ability followed by the PH group, PDRN group, HA group. In addition, transforming growth factor ($TGF-{\beta}$) and vascular endothelial growth factor (VEGF), such as in the growth factor was similar to the results of staining of tissue lesions. In conclusion, it is determined that the low molecular weight PDRN has the therapeutic effect to the wound, and could be used as a functional material of cosmetics and medical industries.

Pre-service Teachers' Development of Science Teacher Identity via Planning, Enacting and Reflecting Inquiry-based Biology Instruction (예비교사들의 과학 교사 정체성 형성 -생명과학 탐구 수업 시연 및 반성 과정을 중심으로-)

  • An, Jieun;Kim, Heui-Baik
    • Journal of The Korean Association For Science Education
    • /
    • v.41 no.6
    • /
    • pp.519-531
    • /
    • 2021
  • This study investigates the science teacher identity of pre-service science teachers (PSTs) in the context of a teaching practice course. Twenty-two PSTs who took the 'Biological Science Lab. for Inquiry Learning' course at the College of Education participated in this study. Artifacts created during the course were collected, and the teaching practices and reflections were recorded and transcribed. In addition, semi-structured interviews were conducted with nine PSTs, recorded, and transcribed. We found the science teacher identity was not well revealed at the beginning of the course. Authoritative discourse appeared in the early oral reflections of PSTs, indicating that the PSTs perceived oral reflection activities as 'evaluation activities for teaching practice'. This perception shows that pre-service teachers participate in teaching practice courses as students attending a university, performing tasks and receiving evaluations from instructors. After the middle of the course, discourses showing the science teacher identity of the PSTs were observed. In the oral reflection after the middle part, dialogic discourses often arose, showing that the PSTs perceive the oral reflection activities as a 'learning activity for professional development'. In addition, in the second half, discourse appeared to connect and interpret one's experience with the teacher's activity, indicating that the PSTs perceive themselves as teachers at this stage. In addition, the perception of experimental classes was expanded through the course. During the course, the practice of equalizing the authority of the participants, providing a role model for reflection, and experiencing various positions from multiple viewpoints in the class had a positive effect on the formation and continuation of the teacher identity. This study provides implications on the teacher education process for teacher identity formation in PSTs.

A Survey of Weather Forecasting Software and Installation of Low Resolution of the GloSea6 Software (기상예측시스템 소프트웨어 조사 및 GloSea6 소프트웨어 저해상도 설치방법 구현)

  • Chung, Sung-Wook;Lee, Chang-Hyun;Jeong, Dong-Min;Yeom, Gi-Hun
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
    • /
    • v.14 no.5
    • /
    • pp.349-361
    • /
    • 2021
  • With the development of technology and the advancement of weather forecasting models and prediction methods, higher performance weather forecasting software has been developed, and more precise and accurate weather forecasting is possible by performing software using supercomputers. In this paper, the weather forecast model used by six major countries is investigated and its characteristics are analyzed, and the Korea Meteorological Administration currently uses it in collaboration with the UK Meteorological Administration since 2012 and explains the GloSea However, the existing GloSea was conducted only on the Meteorological Administration supercomputer, making it difficult for various researchers to perform detailed research by specialized field. Therefore, this paper aims to establish a standard experimental environment in which the low-resolution version based on GloSea6 currently used in Korea can be used in local systems and test it to present the localization of low-resolution GloSea6 that can be performed in the laboratory environment. In other words, in this paper, the local portability of low-resolution Globe6 is verified by establishing a basic architecture consisting of a user terminal-calculation server-repository server and performing execution tests of the software.

Development of Buried Type TDR Module for Leak Detection from Buried Pipe (매설관 주변부 누수 탐지를 위한 매설형 TDR 모듈 개발)

  • Hong, Wontaek
    • Journal of the Korean GEO-environmental Society
    • /
    • v.22 no.11
    • /
    • pp.31-37
    • /
    • 2021
  • To prevent accidents due to the cavities and loosened layers formed due to water leakage from the deteriorated buried pipes, evaluation of the changes in water contents around the buried pipes is required. As a method to evaluate the water contents of the soils, time domain reflectometry (TDR) system can be adopted. However, slender electrodes used in standard TDR probe may be damaged when buried in the ground. Thus, in this study, buried type TDR module was developed for the evaluation of the water contents with maintaining required shape of the electrodes in the ground. The TDR module is composed of three electrodes connected to the core conductor and outer conductor and a casing to prevent deformation and maintain alignment of the electrodes in the ground. For the verification of TDR waveforms measured using the TDR module, comparative analysis was conducted with the TDR waveforms measured using the standard TDR probe, and the relationship between the volumetric water content of the soils and the travel time of the guided electromagnetic wave was constructed. In addition, a model test was conducted to test the applicability of the buried type TDR module, and the experimental result shows that the TDR module clearly evaluates the changes in volumetric water contents due to the leakage from the modeled buried pipe. Therefore, the buried type TDR module may be effectively used for the health monitoring of the buried pipe and the evaluation of the water contents around the pipes buried in the urban pavements.

Discussions on the Reconstruction of Visual Illusion in Dynamic Images - Take of Paul Sermon as an example (다이나믹 이미지 예술 중 착시의 재구성에 관한 연구 - 폴 셔먼의 을 중심으로)

  • GAO, XIAOYA;Paik, Joonki
    • Journal of the Korea Convergence Society
    • /
    • v.12 no.10
    • /
    • pp.189-201
    • /
    • 2021
  • The art of dynamic images has experienced three development stages, including experimental films, recording art, and new media image. By introducing all kinds of new materials, new media to the art, and the art of dynamic images has created more freedom for art creation. With the development of digital information technology, dynamic image works have put forward an increasingly high requirement of visual art. The combination of dynamic images and visual illusion can give rise to different forms and expression methods, thus endowing artworks with more vigor. This paper provides an overview by sorting out the lineage and development of dynamic images in the background, as well as understanding the application and performance of contrasted visual illusion. Based on the understanding of the characteristics of visual illusion, we discuss the new characteristics of applying the theory of visual illusion to new media dynamic images in relation to the technical approach of dynamic images. Through the analysis of specific works of Telematic Vision, we search for its reasonable combination and find the appropriate technical means of implementation. We discuss how to use digital multimedia technology and spatial optical illusion to make the design more novel and impactful, and consider how the combination of digital dynamic image technology and visual illusion should be interpreted and applied.

The Relationship of Country Image, Product-Country Image, and Purchase Intention of Korean Products: Focusing on Differences among Ethnic Groups in South Africa

  • Lee, You-Kyung;Robb, Charles Arthur
    • Journal of Korea Trade
    • /
    • v.23 no.6
    • /
    • pp.33-51
    • /
    • 2019
  • Purpose - The purpose of this study is to provide practical implications for Korean companies searching for new market opportunities. From the experimental analysis, the impact of country image on product-country image and purchase intention of Korean products are measured. In addition, this study disaggregates the impacts of country image and product-country image and purchase intention among ethnic groups in South Africa for searching further useful implications. Design/methodology - To examine South African consumers' country image and product-country image towards Korean products, data were collected between June and July 2019 through an online questionnaire, and 335 questionnaires were used for analysis. Firstly, the multivariate analysis was conducted to examine the general tendency of South African consumers' perceptions of country image to Korea, product-country image, and purchase intention among three ethnic group consumers. Then in order to verify the country image model and hypotheses of the study, we analyzed the structural models for each of the three ethnic groups and compared the sizes of the path coefficients for each groups. To compare the difference of path coefficients across ethnic groups, configural invariance, metric invariance, and scalar invariance tests were conducted sequentially. Findings - In the black and white ethnic groups, the country image had a statistically significant impact on product-country image, but it did not affect the purchase intention to Korean products. The product-country image showed a statistically significant impact on the purchase intention to Korean products in both ethnic group. However, in the coloured ethnic group consumer, the country image had a significant effect on the product-country image, but it did not affect the purchase intention of Korean products. In addition, the product-country image did not have a significant influence on the purchase intention of coloured ethnic group consumers unlike black and white ethnic group consumers. The results of this study suggest that even though differences in terms of the impact of CoI on PCI and PI were investigated for the sample of white, coloured, and black respondents, the groups seemed to respond in a reasonably comparable manner. Originality/value - South Africa occupies more than 20% of Africa's total GDP in sub-Saharan Africa and is a hub for Southern African logistics as a hub for Korean companies to enter Africa. However, it is rare to find a study focused on the determinants of consumer behavior in South Africa. In particular, this study disaggregates the impacts of country image and product-country image on consumer behavior across ethnic groups in South Africa. Therefore, this study could provide practical implications for Korean firms which desire to diversify their export markets and pioneer future markets.

The Protective Effect of Arecae Semen and Coptidis Rhizoma in a Chronic Reflux Esophagitis Rat Model (만성 역류성 식도염 모델에서 빈랑(檳榔)와 황련(黃連) 복합물의 보호 효과)

  • Lee, Se Hui;Lee, Jin A;Shin, Mi-Rae;Lee, Ji Hye;Roh, Seong-Soo
    • The Journal of Internal Korean Medicine
    • /
    • v.42 no.1
    • /
    • pp.11-24
    • /
    • 2021
  • Objective: Chronic reflux esophagitis (CRE), characterized by esophageal mucosa ulcer, is caused by continuous backflow of gastric acid and consequent inflammation due to unstable gastroesophageal sphincter. The aim of the present study was to clarify the effect of an Arecae Semen and Coptidis Rhizoma mixture (AC-mix) on CRE. Methods: CRE was surgically induced in SD rats with three experimental groups used: normal; CRE control; and CRE treatment (200 mg/kg AC-mix). Blood and esophageal tissue were collected after two weeks of drug administration. The anti-oxidant activity of the AC-mix was measured by total polyphenol and total flavonoid contents as well as by radical scavenging activity with protein levels evaluated using western blotting. Results: CRE damage to the esophageal mucosa was significantly reduced in the AC-mix group as compared with the controls, and administration of the AC-mix was seen to inhibit NF-κBp65 activity. Consequently, the inactivation of NF-κBp65 significantly inhibited inflammatory mediators such as COX-2 and iNOS. Moreover, the anti-oxidant enzyme HO-1 significantly increased through activation of the Nrf2-Keap1 pathway. Matrix metalloproteinase-2 (MMP-2), which can break down collagen from the basement membrane and extracellular matrix, was decreased following AC-mix treatment, and elevated levels of MMP-2 were regulated by its tissue inhibitor. Conclusions: These results show that AC-mix can alleviate esophageal mucosa ulcer though inhibition of the NF-κBp65 inflammatory pathway and enhancement of the anti-oxidant Nrf2-Keap1 pathway.

Compression of CNN Using Low-Rank Approximation and CP Decomposition Methods (저계수 행렬 근사 및 CP 분해 기법을 이용한 CNN 압축)

  • Moon, HyeonCheol;Moon, Gihwa;Kim, Jae-Gon
    • Journal of Broadcast Engineering
    • /
    • v.26 no.2
    • /
    • pp.125-131
    • /
    • 2021
  • In recent years, Convolutional Neural Networks (CNNs) have achieved outstanding performance in the fields of computer vision such as image classification, object detection, visual quality enhancement, etc. However, as huge amount of computation and memory are required in CNN models, there is a limitation in the application of CNN to low-power environments such as mobile or IoT devices. Therefore, the need for neural network compression to reduce the model size while keeping the task performance as much as possible has been emerging. In this paper, we propose a method to compress CNN models by combining matrix decomposition methods of LR (Low-Rank) approximation and CP (Canonical Polyadic) decomposition. Unlike conventional methods that apply one matrix decomposition method to CNN models, we selectively apply two decomposition methods depending on the layer types of CNN to enhance the compression performance. To evaluate the performance of the proposed method, we use the models for image classification such as VGG-16, RestNet50 and MobileNetV2 models. The experimental results show that the proposed method gives improved classification performance at the same range of 1.5 to 12.1 times compression ratio than the existing method that applies only the LR approximation.

Compressive and Flexural Properties of Concrete Reinforced with High-strength Hooked-end Steel Fibers (고강도 후크형 강섬유로 보강된 콘크리트의 압축 및 휨 성능)

  • Wang, Qi;Kim, Dong-Hwi;Yun, Hyun-Do;Jang, Seok-Joon;Kim, Sun-Woo
    • Journal of the Korea institute for structural maintenance and inspection
    • /
    • v.25 no.6
    • /
    • pp.209-217
    • /
    • 2021
  • This paper investigates the effect of high strength hooked-end steel fiber content and aspect ratio on the compressive and flexural performance of concrete. A total of ten mixtures were prepared and tested. Concretes with specific compressive strength of 30 MPa were reinforced with three different aspect ratios (l/d) of steel fibers 64, 67, and 80 and three different percentages of steel fibers 0.25, 0.50, and 0.75% by volume of concrete. Tensile strengths of steel fibers with l/d of 64, 67, and 80 are 2,000, 2,400, and 2,100 MPa, respectively. The compressive and flexural properties of plain and steel fiber-reinforced concrete (SFRC) mixtures were evaluated and compared. The experimental results indicated that the incorporation of high-strength hooked-end steel fibers had significant effects on the compressive and flexural performance of concrete. With the increase of steel fiber content, compressive performances, such as Poisson's ratio and toughness, of concrete were improved. The steel fibers with the least l/d of 67 resulted in a larger enhancement of compressive performances. The residual flexural strength, that is, post-cracking flexural resistance and toughness, of concrete is mainly depended on the dosage and aspect ratio of steel fibers. The residual flexural strength at serviceability (SLS) and ultimate limit state (ULS) defined in fib Model Code 2010 (MC2010) is increased as the fiber content and aspect ratio increase.

FEA Simulations on Water Absorption in Various Pre-Cracked Concretes (유한요소해석에 기반한 콘크리트 균열 조건에 따른 수분흡수 현상 분석)

  • Kim, Kun-Soo;Park, Ki-Tae;Kim, Jaehwan
    • Journal of the Korea institute for structural maintenance and inspection
    • /
    • v.25 no.5
    • /
    • pp.68-75
    • /
    • 2021
  • This study performed simulating water absorption in various pre-cracked concretes. 2D-Finite Element Analysis (2D-FEA) model was developed based on experimental results on the amount of absorbed water in concrete with the exposure time. Results from the 2D-FEA showed that both crack width and crack depth strongly affect the amount of absorbed water in cracked concrete. In addition, water absorption rate is introduced and a predictive equation is suggested to estimate the rate in order to quantify the amount of absorbed water in cracked concrete. It was confirmed that water absorption in concrete having less than 150 mm crack depth was dominated as a main transport factor regardless of crack width. Therefore, considering that steel corrosion caused by chlorides dissolved in water mainly occurs in reinforced concrete structures, it is necessary that crack depth as well as crack width should be investigated in reinforced concrete structures at the time of field-inspection.