• The Journal of Internal Korean Medicine
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• v.45 no.1
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• pp.55-74
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• 2024

Objectives: This study reviewed the status of adverse event (AE) reporting in VigiAccess using anti-obesity agents as examples and explored the possibility of its use and future challenges. Methods: AE reports related to some representative drugs among herbal medicines (HMs), complex HM prescriptions, ingredients of supplements, and over-the-counter and prescription medicines were investigated using VigiAccess on February 1, 2024. Results: AE reports on prescription drugs were overwhelmingly higher than those on HMs or supplements. Although most reports were submitted from North America, reports on Ephedra sinica and green tea extract (GTE) were more from Asia and Europe, respectively. The female population reported more, and the difference in the sex ratio was the smallest for Ephedra spp. The age group was concentrated on young adults, but many older patients reported GLP-1 receptor agonist-related AEs. Symptoms related to the gastrointestinal and nervous systems were most commonly reported, but mental and cardiac disorders were common in Ephedra-type HMs. Hepatobiliary disorders are also commonly found in GTE-related reports. Conclusions: VigiAccess was useful for easily checking the global status of AE reporting for prescription drugs. However, several limitations were observed in using VigiAccess for HMs because of the few reports. Thus, it is necessary to increase the number of reports by education and to promote AE reporting among HM prescribers and users. The full range of HMs should be included in the pharmacovigilance system, and the coding and classification of HMs should be revised.

• Korean Journal of Cognitive Science
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• v.11 no.3_4
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• pp.83-93
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• 2000

The effect of immediate and delayed recognition memory on event-related potential (ERP) was studied using a continuous recognition memory task and event-related potential (ERP). Among 240 stimulus words 40 words were not repeated. 100 were immediately repeated and 100 were repeated after 5 intervening words. All words presented only once during the experiment were referred to as new words. Subjects responded faster and more accurately to words repeated immediately than to new words a and to those repeated after intervening words. In terms of ERP results the immediately repeated words were associated with large P300 amplitude, early P300 latency and a absence of N400. while words repeated after a delay were associated with small P300 a amplitude. late P300 latency and the presence of N400. N400 was elicited only to new w words and to those repeated after a delay. The general morphology of the waveform was s similar for three stimulus-presentation conditions until around 3l0ms after the onset of stimulus. These results indicate that immediate and delayed recognition memory could be dissociated into two distinct processes possibly being mediated by different cerebral mechanism, and the dissociation between two types of recognition memory emerges around 3l0ms poststim'ulus. The immediate and delayed recognition memory for words are considered in terms of template matching and memory searching.

• Journal of The Korean Society of Agricultural Engineers
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• v.48 no.7
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• pp.17-22
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• 2006

Potential application topics of KOMPSAT-3 image in the field of precision agriculture are suggested. The topics can be categorized as fundamental and applied ones that have contents of static and dynamic characteristics respectively. As fundamental topics, precision information of agriculture that is related to farmland and its crop attributes, precision information of rural infrastructure that is related to rural village and its facilities, precision information of stream environment that is related to rural water resources and its facilities, and precision information of eco-environment that is especially related to riparian ecology and environmental status are included. As applied topics, precision rural water resources that has thematic contents of continuous and event-based runoff, spatial and temporal soil moisture and evapotranspiration, precision agricultural watershed environment that has the contents of spatial and temporal soil loss, sediment and pollutants transport, and precision temporal and spatial crop growth that has the contents of temporal crop texture, spectral reflectance, leaf area index, spatial crop protein information.

• Proceedings of the KSRS Conference
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• v.1
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• pp.432-435
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• 2006

Potential application topics of KOMPSAT-3 image in the field of precision agriculture are suggested. The topics can be categorized as fundamental and applied ones that have contents of static and dynamic characteristics respectively. As fundamental topics, precision information of agriculture that is related to farmland and its crop attributes, precision information of rural infrastructure that is related to rural village and its facilities, precision information of stream environment that is related to rural water resources and its facilities, and precision information of eco-environment that is especially related to riparian ecology and environmental status are included. As applied topics, precision rural water resources that has thematic contents of continuous and event-based runoff, spatial and temporal soil moisture and evapotranspiration, precision agricultural watershed environment that has the contents of spatial and temporal soil loss, sediment and pollutants transport, and precision temporal and spatial crop growth that has the contents of temporal crop texture, spectral reflectance, leaf area index, spatial crop protein information.

• Proceedings of the KIEE Conference
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• 2001.11c
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• pp.212-214
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• 2001

Siphons and traps are special structures of Petri nets with closely related to liveness for the deadlock analysis of Discrete Event Dynamic Systems. It can analysis the liveness of Petri nets using the siphon and trap without to check reachability.[1] Deadlock analysis approach we proposed is based on the notion of potential deadlock which are siphons that eventually become empty. And in this paper, we proposed a initial marking method by siphon to avoid and to prevent deadlock. It is shown that our approach is more efficient than classical state enumeration approach.

• The Korean Journal of Applied Statistics
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• v.25 no.5
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• pp.775-783
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• 2012

Several statistical models for bivariate poisson data are suggested and used to analyze 2011 K-league data. Our interest is composed of two purposes: The first purpose is to exploit potential attacking and defensive abilities of each team. Particular, a bivariate poisson model with diagonal inflation is incorporated for the estimation of draws. A joint model is applied to estimate an association between poisson distribution and probability of draw. The second one is to investigate causes on scoring time of goals and a regression technique of recurrent event data is applied. Some related future works are suggested.

• Journal of the Korean Society of Safety
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• v.18 no.3
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• pp.75-80
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• 2003

This paper presents a set of typical pseudo-accident scenarios related to major equipments in petrochemical plants, which would be useful for performing such quantitative risk analysis techniques as fault tree analysis, event tree analysis, etc. These typical scenarios address what the main hazard of each equipment might be and how the accident might develop from an "initiating event". The proposed set of accident scenarios consists of total thirteen (13) scenarios specific for five (5) major equipments like reactor, distillation column, etc., and has been determined and screened out of one hundred and twenty-five (125) potential accident scenarios that were generated by performing semi-quantitative risk analysis practically for twenty-five (25) petrochemical processes, considering advices from the operation experts. It is assumed that with simple consideration or incorporation of plant-specific conditions only, the proposed accident scenarios could be easily reorganized or adapted for the relevant process with less time and labor by the safety engineers concerned in the petrochemical industries.ndustries.

• 제어로봇시스템학회:학술대회논문집
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• 1993.10b
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• pp.283-287
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• 1993

We constructed morphological filter for single sweep records of event-related potential (ERP), especially P300 waveform. By combining 4 basic operations; erosion, dilation, opening and closing, we can derive any desired filters whose property fits the current objectives. The morphological filter for single sweep records of ERP was constructed by taking account of the features of the signal and noise components. The morphological filter has superior properties of separating the signal ancl the noise even existing within a same frequency band. The constructed morphological filter was tested by using simulation data of ERP and then applied to actual ERP data of a normal subject. The results proved that the constructed morphological filter was an appropriate tool for single sweep records of ERP.

• Journal of Biomedical Engineering Research
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• v.41 no.1
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• pp.22-27
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• 2020

Auditory stimuli are commonly used in various electroencephalogram experiments, also in EEG-based brain-computer interface systems. However, using conventional earphones that blocks the ear canal attenuates or even blocks external environmental sound which might cause loss of crucial information from surroundings. Instead, bone-conductive earphones are able to deliver sound through vibration without blocking the ear canal. To investigate the feasibility of the bone-conductive earphones for auditory-stimuli based experiments, we compared N100 event-related potential features as well the event-related spectral perturbation and inter-trial coherence of auditory steady-state response between conventional and bone-conductive earphones. The results showed no significant differences between bone conduction and conventional earphones regardless of distinct sound pressures. This result shows that bone conductive earphones can be used for auditory experiments when the environmental sound is crucial to the user.

• Biomedical Science Letters
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• v.26 no.1
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• pp.14-21
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• 2020

Quantitative evaluation of the sense of smell is done by the olfactory event-related potential (OERP) test. OERP consists of N1, P1, N2, P2, and P3, of which N1 and P1 latency are known to be affected by the concentration of odor stimuli associated with the pre-sensory phase and P2 and P3 are the stages at which odors are perceived and are known to change by subjective evaluation of the stimulus. The purpose of this study was to clarify the correlation between the expression of OERP and the subjective evaluation of the object on the fragrance stimulus using various fragrances. Therefore, the study examined the relative waveform power ratio, preference for each scent stimulus, and finally the amplitude and latency change of the components of OERP, N1 and P2. In contrast, it was found that the late P2 response waveform was an effective aroma stimulus recognition waveform in OERP compared to the initial response waveforms.