• Title/Summary/Keyword: Environmental tests

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Skin Absorption of Lawsone in Henna Hair Dye and the Effect of Skin Protectants (헤나염모제 사용 시 로우손의 피부흡수 특성 및 피부보호제의 효과)

  • Kim, Ju Yeon;Kim, Bae-Hwan;Kim, Seung Won
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.31 no.2
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    • pp.173-183
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    • 2021
  • Objectives: This study evaluated the skin permeability of lawsone in henna hair dyes to understand the exposure characteristics of henna hair dyes in the human body. It examined the protective effects of protectants by applying protectants A, B, and C to test skin. Methods: Skin absorption tests were conducted using Franz diffusion cells according to OECD test guideline 428. After applying one kind of natural henna hair dye and chemical henna hair dye, respectively, to a standardized pig skin model, samples of receptor fluid were collected at 1h, 3h, 6h, and 24h. The skin permeation of lawsone was determined using HPLC. After the skin absorption experiment, the skin to which hair dye was applied was analyzed to determine the residual amount of lawsone in the skin. Results: The cumulative permeation of both natural and chemical henna hair dyes increased over time, and the natural henna hair dye had a flux value (t=3.194, p<.05) high both in the Kp value (t=3.207, p<.05) and the residual amount (t=22.701, p<.001). For skin treated with a protectant, the cumulative permeation of natural henna hair dye 24h control and the cumulative permeation of protectant A, B, and C increased over time. Flux and Kp values were in the order control > protectant A > protectant C > protectant B. The residual amount (F=4.469, p<.05) was in the order of protectant C > protectant A > protectant B > control. At 3h, the dye application time of natural henna hair dye, the lawsone flux value (F=4.454, p<.05) and Kp value (F=4.455, p<.05) were higher in the control group than in the protectant groups. The 24h cumulative permeation of the chemical henna hair dye increased with time in both the control and the protectant groups, and the flux and Kp values were in the order of protectant A > protectant C > protectant B > control. The residual amount (F=7.901, p<.01) was in the order of protectant B > protectant A> protectant C > control. Conclusions: Within the normal dyeing time for henna hair dye (three hours for natural henna hair dyes and 30 minutes for chemical henna hair dyes) lawsone skin penetration was not observed even when no protective agent was applied. After that time, however, evidence of skin penetration and retention of lawsone and the protective effect of protective agents were observed.

Seismic Performance Evaluation of Concrete Anchors used in Power Plant Equipment by Shaking Table Tests (진동대 실험을 통한 발전기기용 콘크리트 앵커의 성능평가)

  • Lee, Sang-Moon;Jeon, Bub-Gyu;Jung, Woo-Young
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.41 no.1
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    • pp.21-28
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    • 2021
  • The main purpose of this study is to assess the safety of the fixed anchorages subjected to the seismic motion for an operating facilities in the actual power plant. Thus, the experimental study was conducted to investigate the load response in the event of an actual seismic to the anchorages of a nonstructural components. Since there are economic and spatial constraints to study nonstructural components that actually have various forms, alternative test specimens of steel frames with mass were built and the shaking table test was carried out. In order to evaluate the dynamic characteristics and seismic performance, the natural frequency of the target structure was identified through the shaking table test and then the load response characteristics of the anchorage were evaluated by generating an artificial seismic effect like actual seismic. Finally, the structural stiffness was reinforced by fixing the steel frame to the test specimen using bolts, thereby reducing the load transmitted to the anchorage. It will be carried out on the reliability verification of the experiments and areas that have not been carried out due to the site conditions through the analytical approach in the future.

An Empirical Formula of Bearing Capacity on Prebored and Precast Steel Piles (강관 매입말뚝의 지지력 공식 제안)

  • Park, Jong-Jeon;Kim, Do-Hyun;Jung, Gyung-Ja;Jeong, Sang-Seom
    • Journal of the Korean Geotechnical Society
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    • v.37 no.6
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    • pp.5-20
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    • 2021
  • In this study, a modified empirical formula for estimating the bearing capacity of the steel pipe prebored and precast pile was proposed by performing 20 cases of real-scale field pile loading tests. The proposed formula will be based on expanded SPT N-value in order to consider the realistic condition of the surrounding soil. The formula is proposed based on a statistic approach of the data points from the field pile loading test, in order to ensure safe engineering practice while finding a reliable formula. The statistical analysis of the data points from the loading test indicated that the existing formula has been underestimated the bearing capacity of the prebored and precast pile. The proposed formula estimates 15% and 20% higher pile End bearing capacity (qt=230Pdriven(kN/m2)) and the shaft resistance (fmax=3.0NsE(kN/m2)) compared to the existing formula. The accuracy and the stability of the proposed formula was verified by comparing the estimated results with additional field test data. The verification process showed that the proposed formula was estimated to be more accurate than the existing formula.

Tensile Strength Change of Circular Structural member with Artificial Sectional Surface Damage (인위적 표면 단면손상 수준에 따른 원형 부재의 인장성능 변화)

  • Ha, Min-Gyun;Kwon, Tae-Yun;Lee, Won-Hong;Ahn, Jin-Hee
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.25 no.3
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    • pp.100-109
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    • 2021
  • This study was examined the tensile strength change of a circular tubular member with artificial sectional damage on its surface to consider surface sectional damage by corrosion. The tensile strength tests were conducted using circular tubular specimens with artificial sectional damage considering sectional damaged height and width on its surface according to the corrosion level. From the tensile strength test results, it is confirmed that tensile strength of the circular tubular specimens was affected by the damaged circumference (damaged width), not damaged length (damaged height) and their tensile failures were appeared at the minimum section of the artificial sectional damage part. Nonlinear finite-element analyses were conducted considering equivalent sectional damage effect on sectional damaged part in tensile specimens to examine the change in the tensile strength of tubular specimens with artificial sectional damage since it is difficult to estimate the sectional damaged surface condition of the specimens clearly. From the nonlinear finite element analysis results for the tensile test specimens, tensile strengths of test specimens with irregular sectional damaged surface were relatively evaluated to be highly decreased than these of FE analysis model with equivalent sectional damage. Therefore, residual tensile strengths of tensile members with irregular sectional damage as local corrosion can be evaluated and predicted using correlation coefficient between tensile test results and FE analysis results with equivalent sectional damage.

Studies on Derivation of Appropriate Geodetic System Transformation Schemes for Spatial Data (공간정보의 측지기준체계 변환 기법 도출에 관한 연구)

  • Yun, Seonghyeon;Lee, Hungkyu;Song, Jinhun
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.38 no.6
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    • pp.561-571
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    • 2020
  • Seven techniques widely used in the geodetic transformations have been reviewed and compared to figure out their theoretical characteristics. A series of numerical tests were performed about four data sets. This was followed by result analyses in terms of transformation residuals and accuracies together with some hypothesis testings based on the student-t distribution to confirm the statistical significance of the techniques. In the case of the transformation between the geodetic frames implemented in the same system, no statistical significance was revealed in the results of the 3D transformation techniques, even if the testing area becomes large as the Asia-Oceania continent. Among the 2D transformations, it was possible for the NTv2 grid modeling technique to deliver improved transformation accuracy. Finally, it was possible from the results analyzed in this study to propose the Helmert transformation to geodetic control points and the NTv2 technique to the 2D spatial data transformation of the geodetic systems.

A Study on the application method of UPS's Battery Safety for battleship Command and Fire Control System (지휘무장통제체계용 UPS 배터리의 안전성 확보방안 연구)

  • Park, Gun-Sang;Kim, Jae-Yun;Kim, Dong-Gyu
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.3
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    • pp.587-596
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    • 2021
  • Naval battleships have systems to perform special purposes, such as the Command and Fire Control System (CFCS). Some of the this equipment should be equipped with an Uninterruptible Power System (UPS ) to ensure operational continuity and the backup of important data, even during unexpected power outages caused by problems with the ship's power generator. Heavy combat losses can occur if the equipment cannot satisfy the function. Therefore, it is important to design a stable UPS. The battery and Battery Management System (BMS) are two of the most important factors for designing a stable UPS. A power outage will be encountered if the battery and BMS are not stable. The customer will be exposed to abnormal situations, loss of important tactical data, and inability to operate some of the CFCS. As a result, an enhanced safety system should be designed. Thus, this study implemented and verified the improved system in terms of three methods, such as comparative analysis of the batteries, improvement about leakage current of the circuit, and tests of the aggressive environmental resistance to improve the UPS for CFCS.

Trend Analysis of Earthquake Researches in the World (전세계의 지진 연구의 추세 분석)

  • Yun, Sul-Min;Hamm, Se-Yeong;Jeon, Hang-Tak;Cheong, Jae-Yeol
    • Journal of the Korean earth science society
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    • v.42 no.1
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    • pp.76-87
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    • 2021
  • In this study, temporal trend of researches in earthquake with groundwater level, water quality, radon, remote sensing, electrical resistivity, gravity, and geomagnetism was searched from 2001 to 2020, using the journals indexed in Web of Science, and the number of articles published in international journals was counted in relation to the occurrences of earthquakes (≥Mw 5.0, ≥Mw 6.0, ≥Mw 7.0, ≥Mw 8.0, and ≥Mw 9.0). The number of articles shows an increasing trend over the studied period. This is explained by that studies on earthquake precursor and seismic monitoring becomes active in various fields with integrated data analysis through the development of remote sensing technology, progress of measurement equipment, and big data. According to Mann-Kendall and Sen's tests, gravity-related articles exhibit an increasing trend of 1.30 articles/yr, radon-related articles (0.60 articles/yr), groundwater-related articles (0.70 articles/yr), electrical resistivity-related articles (0.25 articles/yr), and remote-sensing-related articles (0.67 articles/yr). By cross-correlation analysis of the number of articles in each field with removing trend effect and the number of earthquakes of ≥Mw 5.0, ≥Mw 6.0, ≥Mw 7.0, ≥Mw 8.0, and ≥Mw 9.0, radon and remote sensing fields exhibit a high cross-correlation with a delay time of one year. In addition, large-scale earthquakes such as the 2004 and 2005 Sumatra earthquake, the 2008 Sichuan earthquake, the 2010 Haiti earthquake, and the 2010 Chile earthquake are estimated to be related with the increase in the number of articles in the corresponding periods.

Comparing Interaction Effects between Causal and Control Factors in College Students' Online Contact and Distribution of Sexually Explicit Material (대학생의 온라인상의 불법 성콘텐츠 접촉과 불법 성콘텐츠 유통의 원인요인과 통제요인의 상호작용효과 비교)

  • Lee, Seong-Sik;Lim, Hyeong Yeon;Shin, Ji-Min
    • The Journal of the Korea Contents Association
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    • v.21 no.5
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    • pp.465-476
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    • 2021
  • This study considers both causal and control factors for explaining both contact and distribution of sexually explicit material and tests their interaction effects for examining buffering effects of control factors in causal process. This study examines the effect of low self-control, differential association with peers and patriarchy family environmental factor as causal factors. It also considers three control factors such as morality. legal punishment, and lack of opportunity and test interaction effect between causal and control factors in both contact and distribution cases. Using data from college students in Seoul, results show that the effects of all causal factors are significant in both contact and distribution of sexually explicit material and the effect of differential association is the most significant. However, their interaction effects between causal and control factors are different across contact and distribution cases. In the contact case, all interaction effects are not significant. It means that causal factors have independent effects and control factors have no buffering effects. However, in the distribution case, the interaction effects between low self-control and morality, between differential association and morality, between patriarchy family and punishment, and between patriarchy family and lack of opportunity are significant. Empirical implications are discussed.

The Influence of Fitting Parameters on the Soil-Water Characteristics Curve in Stability Analysis of an Unsaturated Natural Slope (불포화 자연사면의 안정해석시 흙-함수특성곡선 맞춤계수의 영향)

  • Kim, Jae-Hong;Yoo, Yong-Jae;Song, Young-Suk
    • The Journal of Engineering Geology
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    • v.31 no.2
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    • pp.165-178
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    • 2021
  • The influence of Soil-Water Characteristic Curve (SWCC) fitting parameters for an unsaturated natural slope was evaluated through seepage and slope stability analysis as a function of rainfall. Soil samples were collected from the study area in Jirisan National Park and the physical and mechanical characteristics of unsaturated soil layers were measured in laboratory tests. The saturation depth was calculated via seepage analysis by changing fitting parameters α, the parameter related to the Air Entry Value (AEV) and n, the parameter related to the slope of the SWCC in the range of natural conditions. Slope stability analysis using the limit equilibrium method considered the calculated depth of saturation. Results from seepage analysis for various rainfall conditions indicate the saturation depth in the soil layer suddenly increased as the fitting parameter α decreased; the saturation time for the entire soil layer also decreased. Slope stability analysis considering the calculated depth of saturation shows that the slope safety factor rapidly decreased as the fitting parameter α decreased, whereas the variation in slope safety factor was very small when n increased. Hence, fitting parameter α has a large effect on saturation depth during rainfall and therefore on slope stability, whereas slope stability is relatively unaffected by the fitting parameter n.

Codon Optimization, Soluble Expression and Purification of PE_PGRS45 Gene from Mycobacterium tuberculosis and Preparation of Its Polyclonal Antibody Protein

  • Xu, Tao;Li, Minying;Wang, Chutong;Yuan, Meili;Chang, Xianyou;Qian, Zhongqing;Li, Baiqing;Sun, Meiqun;Wang, Hongtao
    • Journal of Microbiology and Biotechnology
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    • v.31 no.11
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    • pp.1583-1590
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    • 2021
  • Studies have demonstrated that PE_PGRS45 is constitutively expressed under various environmental conditions (such as nutrient depletion, hypoxia, and low pH) of the in vitro growth conditions examined, indicating that PE_PGRS45 protein is critical to the basic functions of Mycobacterium tuberculosis. However, there are few reports about the biochemical function and pathogenic mechanism of PE_PGRS45 protein. The fact that this M. tuberculosis gene is not easily expressed in E. coli may be mainly due to the high content of G+C and the use of unique codons. Fusion tags are indispensable tools used to improve the soluble expression of recombinant proteins and accelerate the characterization of protein structure and function. In the present study, His6, Trx, and His6-MBP were used as fusion tags, but only MBP-PE_PGRS45 was expressed solubly. The purification using His6-MBP tag-specific binding to the Ni column was easy to separate after the tag cleavage. We used the purified PE_PGRS45 to immunize New Zealand rabbits and obtained anti-PE_PGRS45 serum. We found that the titer of polyclonal antibodies against PE_PGR45 was higher than 1:256000. The result shows that purified PE_PGRS45 can induce New Zealand rabbits to produce high-titer antibodies. In conclusion, the recombinant protein PE_PGRS45 was successfully expressed in E. coli and specific antiserum was prepared, which will be followed by further evaluation of these specific antigens to develop highly sensitive and specific diagnostic tests for tuberculosis.