• The Journal of the Korea Contents Association
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• v.21 no.2
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• pp.453-461
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• 2021

This study aims to study the effect of service quality of lifelong education in culture and arts on educational satisfaction, intention to continuous use and performance. The service quality of culture and art lifelong education was divided into three dimensions: education quality, administrative quality, and environmental quality. As detailed factors related to quality, six variables were set based on SERVQUAL: convenience, expertise, responsiveness, supportability, empathy, and tangibility. For this study, data were collected from 310 people taking cultural arts lectures at lifelong educational institutions in Seoul, Daegu, and Gumi. Since it was only for lectures related to culture and arts, a total of 256 materials were used for the study, excluding inappropriate materials. A structured questionnaire was used as a data collection method, and a structural model analysis was conducted to verify the hypothesis. As a result of this study, responsiveness among the service quality factors of lifelong education for culture and arts was rejected. In addition, the higher the satisfaction with the culture and art lifelong education institution, the higher the performance and the intention to continue using it. The theoretical and practical implications of this study result were discussed, and future research tasks were presented.

• Environmental and Resource Economics Review
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• v.31 no.2
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• pp.205-232
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• 2022

This study analyzes the effect of the 2^nd pilot test of Tiime of Use (TOU) pricing for Korean households using a two-level electricity demand model. The test, implemented from May to September 2021, was conducted to compare the effects of two TOU pricing rates and the standard rates for households living in apartment and detached house in 7 provinces of Korea. Based on the data on electricity consumption during the test period and during the same period last year of the 1,292 participants and their socio-economic characteristics, this study analyzes (1) whether the relative demand across periods has changed in response to hourly price changes and (2) whether the price responsiveness of daily consumption has changed after the introduction of TOU pricing. The results show that both types of TOU pricing affect neither the relative demand across periods nor the price responsiveness of daily consumption. The reason behind the results could be related to the level of TOU pricing rates and the periodical classification, which were not sufficient to induce changes in the participants' electricity demand patterns.

• The Journal of Information Technology
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• v.5 no.3
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• pp.65-80
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• 2002

A key concern at these days is where to find a suitable location for their business activities, bearing in mind that they must find the right balance between global integration and local responsiveness. This article suggests that globalization may be enabled by Information Technology. It focuses on the sourcing process, an area where globalization is often claimed to be the case. Re-examination of empirical evidence shows that global sourcing is not as generally predominant as is claimed. Consequently inhibitors to global integration exist and these inhibitors are classified into three categories: geographical, relational and environmental inhibitors. The role information technology plays in reducing these inhibitors and formulate propositions that are then illustrated in two case studies. Information technology is proposed to reduce the geographical and relational inhibitors, but it will have no effect on environmental inhibitors. However, the latter category of inhibitors will become more prominent in the future. Information technology thus shifts the balance towards global integration, but simultaneously creates new problems in managing internationalization.

• Economic and Environmental Geology
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• v.56 no.2
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• pp.155-166
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• 2023

Through COVID-19, the importance of supply chain management of raw material minerals has been maximized. In particular, supply chain management is important for rare metals, which are difficult to manage demand and supply, in order to secure raw materials for the parts and materials industry that Korea is actively promoting. In this study, a system was established and evaluated to select Critical minerals that need to respond to Korea's industrial structure and global risks by quantifying tangible and intangible risk factors. Global Supply Concentration, Supplying country risk, Policy Social Environment Regulation, Domestic Import Instability, Risk responsiveness, Market Scale, Demand Fluctuation and Economic Importance were evaluated as evaluation indicators. The degree of risk and risk impact were quantitatively measured using the criticality matrix-criticality level. After evaluating 40 types of minerals used in domestic new growth businesses, 15 types of Critical minerals(Li, Pt, Co, V, REE, Mg, Mo, Cr, Ti, W, C, Ni, Al, Mn, Si) in Korea were selected. The results are expected to be used to establish policies to strengthen resource security and to make decisions to form a company's raw material portfolio.

• Archives of Pharmacal Research
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• v.27 no.9
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• pp.906-911
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• 2004

In order to evaluate estrogenic compounds in natural products, an in vitro detection system was established. For this system, the human breast cancer cell line MCF7 was stably trans-fected using an estrogen responsive chloramphenicol acetyltransferase (CAT) reporter plas-mid yielding MCF7/pDsCAT-ERE119-Ad2MLP cells. To test the estrogenic responsiveness of this in vitro assay system, MCF7/pDsCAT-ERE119-Ad2MLP cells were treated with various concentrations of 17f3-estradiol. Treatments of 10$^{-8}$ to 10$^{-12}$ M 17$\beta$-estradiol revealed significant concentration dependent estrogenic activities compared with ethanol. We used in vitro assay system to detect estrogenic effects in Puerariae radix and Ginseng radix Rubra extracts. Treat-ment of 500 and 50 $\mu\textrm{g}$/ml of Puerariae radix extracts increased the transcriptional activity approximately 4- and 1.5-fold, respectively, compared with the ethanol treatment. Treatment of 500, 50, and 5 $\mu\textrm{g}$/ml of Ginseng radix Rubra extracts increased the transcriptional activity approximately 3.2-,2.7, and 1.4-fold, respectively, compared with the ethanol treatment. These observations suggest that Puerariae radix and Ginseng radix Rubra extracts have effective estrogenic actions and that they could be developed as estrogenic supplements.

• The Korean Journal of Physiology and Pharmacology
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• v.14 no.5
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• pp.273-278
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• 2010

Tropical inhabitants are able to tolerate heat through permanent residence in hot and often humid tropical climates. The goal of this study was to clarify the peripheral mechanisms involved in thermal sweating pre and post exposure (heat-acclimatization over 10 days) by studying the sweating responses to acetylcholine (ACh), a primary neurotransmitter of sudomotor activity, in healthy subjects (n=12). Ten percent ACh was administered on the inner forearm skin for iontophoresis. Quantitative sudomotor axon reflex testing, after iontophoresis (2 mA for 5 min) with ACH, was performed to determine directly activated (DIR) and axon reflex-mediated (AXR) sweating during ACh iontophoresis. The sweat rate, activated sweat gland density, sweat gland output per single gland activated, as well as oral and skin temperature changes were measured. The post exposure activity had a short onset time (p<0.01), higher active sweat rate [(AXR (p<0.001) and DIR (p<0.001)], higher sweat output per gland (p<0.001) and higher transepidermal water loss (p<0.001) compared to the pre-exposure measurements. The activated sweat rate in the sudomotor activity increased the output for post-exposure compared to the pre-exposure measurements. The results suggested that post-exposure activity showed a higher active sweat gland output due to the combination of a higher AXR (DIR) sweat rate and a shorter onset time. Therefore, higher sudomotor responses to ACh receptors indicate accelerated sympathetic nerve responsiveness to ACh sensitivity by exposure to environmental conditions.

• The Journal of the Korea Contents Association
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• v.20 no.12
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• pp.166-179
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• 2020

The purpose of this study is to explore and analyze what has changed in Seoul National University (SNU) since its incorporation, focusing on the perceptions and experiences of its internal members. To this end, semi-structured interviews were conducted with members of SNU, professors, staff, and students. The interview results were presented by categorizing them into changes in the overall evaluation of the incorporation, positive and negative changes, education, research, social contribution, and operating system. Overall, with regard to the changes after incorporation, the members of SNU showed a common perception that it was difficult to feel the change or that there was little change. As for positive changes, they mentioned the expansion of university finances, increased autonomy in operation, and improved responsiveness to environmental changes. As for negative changes, they mentioned the ambiguity of SNU's legal status, and the excessive increase of direct and aggressive influence from outside. In the last part, the main findings were summarized and their meaning and implications were discussed.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.44 no.1
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• pp.26-36
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• 2021

The topic of this study is the field of humanitarian logistics for disaster response. Many existing studies have revealed that compliance with the golden time in response to a disaster determines the success or failure of relief activities, and logistics costs account for 80% of the disaster response cost. Besides, the agility, responsiveness, and effectiveness of the humanitarian logistics system are emphasized in consideration of the disaster situation's characteristics, such as the urgency of life-saving and rapid environmental changes. In other words, they emphasize the importance of logistics activities in disaster response, which includes the effective and efficient distribution of relief supplies. This study proposes a mathematical model for establishing a transport plan to distribute relief supplies in a disaster situation. To determine vehicles' route and the amount of relief for cities suffering a disaster, it mainly considers the urgency, effectiveness (restoration rate), and uncertainty in the logistics system. The model is initially developed as a mixed-integer nonlinear programming (MINLP) model containing some nonlinear functions and transform into a Mixed-integer linear programming (MILP) model using a logarithmic transformation and piecewise linear approximation method. Furthermore, a minimax problem is suggested to search for breakpoints and slopes to define a piecewise linear function that minimizes the linear approximation error. A numerical experiment is performed to verify the MILP model, and linear approximation error is also analyzed in the experiment.

• IMMUNE NETWORK
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• v.23 no.2
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• pp.15.1-15.17
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• 2023

Innate lymphoid cells (ILCs) are critical immune-response mediators. Although they largely reside in mucosal tissues, the kidney also bears substantial numbers. Nevertheless, kidney ILC biology is poorly understood. BALB/c and C57BL/6 mice are known to display type-2 and type-1 skewed immune responses, respectively, but it is unclear whether this extends to ILCs. We show here that indeed, BALB/c mice have higher total ILCs in the kidney than C57BL/6 mice. This difference was particularly pronounced for ILC2s. We then showed that three factors contributed to the higher ILC2s in the BALB/c kidney. First, BALB/c mice demonstrated higher numbers of ILC precursors in the bone marrow. Second, transcriptome analysis showed that compared to C57BL/6 kidneys, the BALB/c kidneys associated with significantly higher IL-2 responses. Quantitative RT-PCR also showed that compared to C57BL/6 kidneys, the BALB/c kidneys expressed higher levels of IL-2 and other cytokines known to promote ILC2 proliferation and/or survival (IL-7, IL-33, and thymic stromal lymphopoietin). Third, the BALB/c kidney ILC2s may be more sensitive to the environmental signals than C57BL/6 kidney ILC2s since they expressed their transcription factor GATA3 and the IL-2, IL-7, and IL-25 receptors at higher levels. Indeed, they also demonstrated greater responsiveness to IL-2 than C57BL/6 kidney ILC2s, as shown by their greater STAT5 phosphorylation levels after culture with IL-2. Thus, this study demonstrates previously unknown properties of kidney ILC2s. It also shows the impact of mouse strain background on ILC2 behavior, which should be considered when conducting research on immune diseases with experimental mouse models.

• Journal of the Korean Society for Library and Information Science
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• v.58 no.3
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• pp.333-358
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• 2024

To promote libraries as "Libraries for All," it is essential to assess the current state of regional library infrastructures and explore policy support strategies for their improvement. This study develops the 'Library Vitality Index' as a metric to evaluate libraries' capabilities as sustainable infrastructures. The index assesses various aspects, including libraries' environmental responsiveness, accessible design, level of digital transformation, and capacity to provide universal cultural services. The research involved a comprehensive review of domestic and international cases, Delphi surveys, and expert group interviews to derive the final set of indicators. These indicators were weighted based on their importance using AHP analysis. The final index consists of three components: regional library activation (300 points), individual library capacity (470 points), and feedback systems (30 points), with a total of 800 points. The index includes 108 items, divided into 14 for regional library activation, 88 for individual library capacity, and 6 for feedback systems.