Journal of Physiology & Pathology in Korean Medicine
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v.26
no.3
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pp.320-324
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2012
Osteoporosis is an important public health issue in postmenopausal women. It is a major public health concern and is widely believed that osteoporosis results from imbalance between bone resorption and bone formation. Recently natural products from plants have been extensively studied as therapeutic drugs to treat and prevent various diseases. Hoelen (scientific name, Poria cocos) is a mushroom that is used in traditional Chinese medicine. Hoelen exhibits anti-inflammatory activity and has a protective effect on tumor progression. However, the effect of hoelen in osteoclast differentiation remains unknown. Thus, we examined the effect of hoelen in receptor activator of nuclear factor-${\kappa}B$ ligand (RANKL)-induced osteoclast differentiation. Hoelen significantly inhibited RANKL-induced osteoclast differentiation in bone marrow-derived macrophages (BMMs) in dose dependent manner without toxicity. Also, we showed that hoelen significantly inhibited the mRNA expression of tartrate-resistant acid phophatase (TRAP) and nuclear factor of activated T cells 1 (NFATc1) in BMMs treated with RANKL. In Particular, hoelen greatly inhibited the protein expression of NFATc1. Ectopic expression of NFATc1 partially reverses hoelen-mediated inhibition of osteoclast differentiation. Taken together, our results demonstrated that hoelen may be useful treatment option of bone-related disease such as osteoporosis, reumatoid arthritis, and periodontitis.
The purpose of this study is to examine clothing benefits seeking and buying behavior depending on the level of environmental awareness. The results showed a significant relationship between the level of environmental awareness and the factors of demographic characteristics, such as age, marital status, educational status, and type of housing, occupation, and average household income. However, there was no significant difference between those by gender. In relationship between the level of environmental awareness and clothing benefits seeking behavior, there were significant differences between the following groups. such as social stability-oriented, brand-oriented, individuality-oriented, and comfort-oriented group. With regard to the relationship between environment-friendly consuming behavior and demographic characteristics, there were significant differences in all factors of the demographic characteristics. Buying behavior showed a significant relationship with all factors of demographic characteristics except type of housing. Using behavior matched a significant relationship with all factors of demographic characteristics. Disposition behavior demonstrated a significant relationship with all factors except marital status. In terms of the effect of clothing benefits sought on the environment-friendly consuming behavior, the results suggested a significant relationship of brand-oriented, individuality-oriented, comfort-oriented, and price-oriented factors. Buying behavior showed a significant relationship with brand-oriented, comfort-oriented, and price-oriented factors. Using behavior demonstrated a strongly significant relationship with comfort-oriented factor while disposition behavior suggested a strong relationship with price-oriented factor.
Tetrabromobisphenol A (TBBPA) is the most widely used BFR (brominated flame retardants) as a reactive flame retardant in printed circuit boards, and as additive applications in several types of polymers. The purpose of this study is to assess the adverse effects of TBBPA on the benthic amphipod (Hyalella azteca). Results on the acute toxicity of TBBPA using Hyalella azteca showed that NOEC and LOEC are 100mg/kg and 200mg/kg, respectively. In addition, when chronic toxicity of TBBPA was investigated at the concentration ranges between 0.01 to 100mg/kg, it was found that NOECs are $10mg/kg(fecundity){\sim}100mg/kg(viability)$, respectively. Significant fecundity inhibition was appeared at 100mg/kg of TBBPA, however, this concentration did not show severe adverse effect on weight increment. The values of PNEC were determined as 0.1mg/kg (fecundity) and 1mg/kg (lethal effect), respectively, using a safety factor suggested by EU and OECD.
Park, Hee-Jin;Woo, Kyung-Sook;Moon, Chan-Seok;Kim, Geun-Bae;Kang, Tack-Shin;Chung, Eun-Kyung;Kim, Yong-Bae;Son, Bu-Soon
Journal of Korean Society of Occupational and Environmental Hygiene
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v.24
no.2
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pp.137-145
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2014
Objectives: The study examines the relation between urinary arsenic concentration and blood pressure, which is a risk factor of cardiovascular disease. Materials: In this study, the urinary arsenic concentration, history of diagnosed disease, and blood pressure of 782 local residents in Gwangyang, Yeosu, and Hadong regions from May 2007 to July 2007. Results: The urinary arsenic concentration of total participants was $9.06{\mu}g/g-ct$. The logistic regression analysis of medical diagnosed history and urinary arsenic concentration, showed statistically significance (p<0.05) of high urinary arsenic concentration in participants with diagnosed hypertension. In addition, diagnosed hypertension it was observed that the high blood pressure was related with the pulse pressure. Conclusions: The arsenic concentration level was low in this study, but the exposure to low levels of arsenic has an effect on hypertension. Also, hypertension is related to pulse pressure and mean arterial blood pressure as well as being risk factor of cardiovascular disease. Therefore, close supervision of low -level arsenic exposure is needed.
Arsenic (As) is one of the heavy metals which causes acute bio-toxicity even at low concentration and has disastrous effect on environment. In some countries, As contamination has become alarming and increasing day by day as consequences of unsustainable management practices. Many existing physical, chemical and biological processes for As removal from water system are not feasible due to techno-economic limitations. The present study highlights the scope of biological strategy for As removal through phytoextraction. Arsenic uptake and accumulation in the biomass of three plant species and their As tolerance abilities have been investigated to develop an efficient phytoextraction system in combination of these plant species. Three non-crop plant species, Pteris vittata; Mimosa pudica, and Eichhornia crassipus were treated with 0-200 mg/L As in liquid nutrient solution for 14 days. P. vittata accumulated total 9,082.2 mg (8,223 mg in fronds) As/kg biomass and Eichhornia total 6,969 mg (4,517 mg in fronds)/kg biomass at 200 mg/L As concentration, respectively. Bioaccumulation factor (BF) and translocation factor (TF) were estimated to differentiate between excluders, accumulators and accumulation in above ground biomass. Pteris and Eichhornia have highest BF (67 and 17) and TF (64 and 3), respectively. In contrast, Mimosa accumulated up to 174 mg As/kg plant biomass which is low in comparison with other two plants, and both BF and TF were ${\leq}1$. This study reveals that Pteris and Eichhornia are As hyperaccumulator, and potential candidates for As removal from water system.
The purpose of this study is to enhance elementary students' awareness of environment-friendly life and help them to prepare for a better life in the future. To achieve this purpose we examined the effect typical environmental experience-based learning activities, which were based on the local circumstances with high environmental-educational potential, have on the attitudes toward environment-friendly life. This study was carried out on the basis of typical environmental experience-based learning in the small class size. The research group used was composed of one sixth grade elementary school class called Sangroksu, whose total students were 9. The research period lasted from March 2005 to February 2006. To analyze the result of this study, two research methods were applied simultaneously : quantitative research methods and qualitative research methods. Especially statistical analysis in quantitative research methods by self-administrated questionnaire was done with SAS program. Qualitative research methods were analyzed in a cyclic pattern, including the processes of domain analysis, classification analysis, and factor analysis which continued to be associated with data-collecting methods. This research shows the following results. First of all, students have shown meaningful differences after typical environmental experience-based learning activities.(p<.05). Followings are fields of the differences - students‘ interest on the subject, their understanding levels of necessity for basic environmental facilities around us as well as for the kinds of environmental experience-based learning, awareness levels of various environmental problems, consciousness on environment conservation, and the practicing ability of environment - friendly lifestyles. Secondly, We have discovered improvements in the following fields after this study - the knowledge and understanding levels on our environment and human relationships, students' fundamental abilities to work out environmental problems, right ideas and appropriate attitudes on environment protection, the practicing ability of environment-friendly life styles, and their parents' understanding levels on the education related to environment. In conclusion, typical environmental experience-based learning activities have a positive effect on the improvement of elementary school students' environment-friendly life styles.
Journal of Korean Home Economics Education Association
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v.10
no.2
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pp.1-11
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1998
The purpose of this study is to analyze highschool girls' concerns about environmental problems after investigating the actual state of environmental education and to suggest some fundamental changes in the Home Economics classes to improve environmental education. The sample was selected form high school girl students in Kyounggi Province between September 16 and September 26, 1996. Eight hundred twenty (820) first and second grade respondents were used. The data were analyzed by frequency, mean, percentile, factor analysis. Duncan's Multiple Range Test, and Stepwise Multiple Regression. Based on the major findings, the most influential variable was parental attitudes towards environmental conservation and problem. Next in influence was the environmental education provided in Home Economics classes. Also important were the individual student's interest in Home Economics classes, and her belief in the utility of environmental conservation in everyday life. The research conclusions are as follows: 1. We'll find how to relate efficiently the environmental education with everyday life by analyzing thoroughly the text of home economics. 2. We'll develop how to educate students parents properly because parental attitudes to wards the environmental problem have a great effect on students' behaviors. 3. We'll ceinforce environmental education by developing problems, and to motivate them to take real action in the area of environmental conservation.
The main purposes of this study are to find the causality among residents' loyalty to an environmental festival and its influential factors and, based upon the findings, to explore environmental festivals' developmental vision with special reference to Hampyung Butterfly Festival. Under these aims, this study applies structural equation modeling(SEM). The structural model for SEM analysis is composed of four independent variables which consist of residents' attachment(RA) to their region where its own environmental festival is provided, residents' participational intention(RP) to the festival, the economic effects(EE) of the festival, and the communication(CM) between the residents and the festival providers, one intermediate variable, residents' satisfaction(RS) from the festival, and one final dependent variable, residents' loyalty(RL) to the festival. The causality among these variables is hypothesized as follows; Among the independent variables, RP, EE, and CM have effects only on RS and RA has an effect on both RS and RL. And RS has an effect on RL. The facts found from the SEM are summed up as follows; First, (1) RP and CM turn out to have statistically significant effects on RS, (2) RA is confirmed to have a statistically very significant effect on both RS and RL, and (3) RS is also proved to show a statistically very significant effect on RL. Second, the total effects on RL of independent variables are stronger in the order of RA, CM, and RP. Third, EE seems to have no effect on RS, consequently no effect on RL, either. The reason why EE has no effect looks like to be due to environmental festivals' peculiar features. These findings offer the following suggestions for the future of environmental festivals in the part of festival providers. Firstly, to be successful in the festival, they have to provoke RL above all. Second, to do so, they need to encourage RA, CM, and RP in the mentioned order in the long run. Third, but for a short period, they had better concentrate upon promoting RS.
This study was carried out to investigate abiotic and biotic environmental factors affecting homoharringtonine (HHT) contents of Cephalotaxus koreana, whereby, to provide basic information of high value-added industry production of HHT as a promising anti-cancer agent. For correlation between abiotic environmental factors (soil moisture, soil pH, habitat density and temperature) and HHT contents, the contents were highly correlated with soil moisture (0.77) and soil pH (-0.68). For multiple regression analysis of relationship between abiotic environmental factors (soil moisture and soil pH) and HHT contents, soil moisture appeared to be strongly affecting the contents relatively due to being significant at only its regression coefficient ($26.48^{***}$). For the effect of biotic environmental factors (damage index) affecting HHT contents, the contents was quadratic with equation of $H=278.23+1242D-398.87D^2$, also, damage index had strong effect on the contents. Finally, for the result of the most influencing an environmental factor on HHT contents, both damage index and soil moisture were suitable in second polynomial regression, also, damage index ($R^2=0.73^{***}$) was turned out to be more influencing factor than soil moisture ($R^2=0.67^{**}$) on HHT contents relatively. Therefore, we predict that HHT contents in the trees of Cephalotaxus koreana is produced as a chemical defense mechanism triggered by a stress-related damage of fungi or insects.
Kim, Min-Suk;Kim, Yong-Suk;Min, Hyun-Gi;Kim, Jeong-Gyu;Koo, Namin
Korean Journal of Soil Science and Fertilizer
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v.50
no.3
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pp.179-186
/
2017
This study was conducted to identify characteristics of domestic pine forest soils and to elucidate major soil influencing factors for natural regeneration. We analyzed the physico-chemical characteristics of the soil samples collected from 23 pine forests and confirmed the similar results with the forest soil characteristics. Soil pH, organic matter content, total nitrogen, exchangeable Ca, silt content, and exchangeable Al were selected as the major soil factors among the exposed soils through 10 days of pine seedlings exposure and cultivation experiments and statistical analysis. Multiple regression analysis showed that soil pH had a positive effect on specific root length (SRL) of red pine seedlings and exchangeable Al was a significant factor affecting negative change in SRL. Taken together, the reduction of exchangeable Al by soil pH adjustment would be helpful for natural regeneration by restoring the forest and improving the fine root and root integrity of pine seedlings. Therefore, soil pH and exchangeable Al could be recommended as a major soil factor to be carefully considered in the monitoring and management of soil in pine forests that need to be renewed in the future.
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