Environmental Analysis Health and Toxicology

The Korean Society of Environmental Health and Toxicology (환경독성보건학회)
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Toxicity Assessment of Tetrabromobisphenol A with the Benthic Amphipod, Hyalella azteca

저서 단각류인 Hyalella azteca를 이용한 브롬화방염제 Tetrabromobisphenol A의 독성평가

  • Lee, Chul-Woo (Environmental Exposure Assessment Division, National Institute of Environmental Research) ;
  • Song, Sang-Hwan (Environmental Exposure Assessment Division, National Institute of Environmental Research) ;
  • Kim, Hyun-Mi (Environmental Exposure Assessment Division, National Institute of Environmental Research) ;
  • Kim, Hak-Joo (Environmental Exposure Assessment Division, National Institute of Environmental Research) ;
  • Choi, Kyung-Hee (Environmental Exposure Assessment Division, National Institute of Environmental Research) ;
  • Lee, Moon-Soon (Environmental Exposure Assessment Division, National Institute of Environmental Research)
  • 이철우 (국립환경과학원 화학물질평가부 환경노출평가과) ;
  • 송상환 (국립환경과학원 화학물질평가부 환경노출평가과) ;
  • 김현미 (국립환경과학원 화학물질평가부 환경노출평가과) ;
  • 김학주 (국립환경과학원 화학물질평가부 환경노출평가과) ;
  • 최경희 (국립환경과학원 화학물질평가부 환경노출평가과) ;
  • 이문순 (국립환경과학원 화학물질평가부 환경노출평가과)
  • Published : 2007.06.30
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Abstract

Tetrabromobisphenol A (TBBPA) is the most widely used BFR (brominated flame retardants) as a reactive flame retardant in printed circuit boards, and as additive applications in several types of polymers. The purpose of this study is to assess the adverse effects of TBBPA on the benthic amphipod (Hyalella azteca). Results on the acute toxicity of TBBPA using Hyalella azteca showed that NOEC and LOEC are 100mg/kg and 200mg/kg, respectively. In addition, when chronic toxicity of TBBPA was investigated at the concentration ranges between 0.01 to 100mg/kg, it was found that NOECs are $10mg/kg(fecundity){\sim}100mg/kg(viability)$, respectively. Significant fecundity inhibition was appeared at 100mg/kg of TBBPA, however, this concentration did not show severe adverse effect on weight increment. The values of PNEC were determined as 0.1mg/kg (fecundity) and 1mg/kg (lethal effect), respectively, using a safety factor suggested by EU and OECD.

Keywords

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