• 제목/요약/키워드: Electrode array

검색결과 224건 처리시간 0.026초

Multi-Electrode Array를 이용한 뇌 해마의 Total Activity 추산 (Total Activity Estimation of Hippocampal Slice Using Multi-Electrode Array)

  • 이정찬;김지은;조정연;손민숙;박경모;박지호
    • 대한의용생체공학회:의공학회지
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    • 제27권6호
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    • pp.409-417
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    • 2006
  • Research on neural circuit is a difficult area due to complexity and inaccessibility. Due to recent developments, the research using multi-electrode array of cells or tissues has become an important research area. However, there are some difficulties to decode the submerged meaning from huge and complex neural data. Moreover, it needs a harmonic collaboration between informatics and bioscience. In this paper, we have developed a custom-designed signal processing technique for multi-electrode array measured neural responses induced by electrical stimuli to the hippocampal tissue slices of the rat brain. The raw data from hippocampal slice using the multi-electrode array system were saved in a computer. Then we estimated characteristic points in each channel and calculated the total activity. To estimate the points, we used the Polynomial Fitting Approximation Method. Using the calculated total activity, we could provide the histogram or pseudo-image matrix to help interpretation of results.

다중 채널 전극의 제작 및 특성 평가 (Fabrication and Characterization of Multi-Channel Electrode Array (MEA))

  • 성락선;권광민;박정호
    • 대한전기학회논문지:시스템및제어부문D
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    • 제51권9호
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    • pp.423-430
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    • 2002
  • The fabrication and experimentation of multi-channel electrodes which enable detecting and recording of multi-site neuronal signals have been investigated. A multi-channel electrode array was fabricated by depositing 2000${\AA}$ thick Au layer on the 1000${\AA}$ thick Ti adhesion layer on a glass wafer. The metal paths were patterned by wet etching and passivated by depositing a PECVD silicon nitride insulation layer to prevent signals from intermixing or cross-talking. After placing a thin slice of rat cerebellar granule cell in the culture ring located in central portion of the multi-channel electrode plate, a neuronal signal from an electrode which is in contact with the cerebellar granule cell has been detected. It was found that the electrode impedance ranges 200㏀∼1㏁ and the impedance is not changed by cleaning with nitric acid. Also, the impedance is inversely proportion to the exposed electrode area and the cross-talk is negligible when the electrode spacing is bigger than 600$\mu\textrm{m}$. The amplitude and frequency of the measured action potential were 38㎷ and 2㎑, which are typical values. From the experimental results, the fabricated multi-channel electrode array proved to be suitable for multi-site neuronal signal detection for the analysis of a complicated cell network.

유리의 미세 가공을 위한 구리 전극군의 제작과 전기 화학 방전 가공 시험 (Fabrication of Copper Electrode Array and Test of Electrochemical Discharge Machining for Micro Machining of Glass)

  • 정주명;심우영;정옥찬;양상식
    • 대한전기학회논문지:전기물성ㆍ응용부문C
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    • 제53권9호
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    • pp.488-493
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    • 2004
  • In this paper, we present the fabrication of copper electrode array and test of electrochemical discharge machining(ECDM) for glass machining. An array of 72 Cu electrodes is used to machine Borofloat33 glass. The height and diameter of a Cu electrode are 400 $\mu\textrm{m}$ and 100 $\mu\textrm{m}$ respectively. It is fabricated by ICP-RIE, Au-Au thermo-compression bonding, and copper electroplating. Borofloat33 glass is machined by the fabricated copper electrode array in 60 seconds at 55 V. The surface roughness of the machined glass is measured and the machined glass is anodically bonded with silicon.

Electrical resistivity tomography survey for prediction of anomaly in mechanized tunneling

  • Lee, Kang-Hyun;Park, Jin-Ho;Park, Jeongjun;Lee, In-Mo;Lee, Seok-Won
    • Geomechanics and Engineering
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    • 제19권1호
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    • pp.93-104
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    • 2019
  • Anomalies and/or fractured grounds not detected by the surface geophysical and geological survey performed during design stage may cause significant problems during tunnel excavation. Many studies on prediction methods of the ground condition ahead of the tunnel face have been conducted and applied in tunneling construction sites, such as tunnel seismic profiling and probe drilling. However, most such applications have focused on the drill and blast tunneling method. Few studies have been conducted for mechanized tunneling because of the limitation in the available space to perform prediction tests. This study aims to predict the ground condition ahead of the tunnel face in TBM tunneling by using an electrical resistivity tomography survey. It compared the characteristics of each electrode array and performed an investigation on in-situ tunnel boring machine TBM construction site environments. Numerical simulations for each electrode array were performed, to determine the proper electrode array to predict anomalies ahead of the tunnel face. The results showed that the modified dipole-dipole array is, compared to other arrays, the best for predicting the location and condition of an anomaly. As the borehole becomes longer, the measured data increase accordingly. Therefore, longer boreholes allow a more accurate prediction of the location and status of anomalies and complex grounds.

경사 전극 배열을 이용한 각도방향 마이크로 구동부 제작 (Skewed Electrode Array(SEA) and Its Application as an Angular Microactuator)

  • 최석문;박성준
    • 융복합기술연구소 논문집
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    • 제1권2호
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    • pp.16-24
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    • 2011
  • The angular electrostatic microactuator using skewed electrode array (SEA) scheme was proposed. The moving and fixed electrodes are arranged to make the driving force perpendicular to the rotating moment of arm. By changing the electrode overlap length, the magnitude of electrostatic force and stable displacement will be changed. In order to optimize the design, electrostatic FE analysis were carried out and the empirical force model was established for SEA. Simulation was performed to make the comparison between conventional actuators and SEA. The proposed SEA generates actuating torque 2 times greater than a comb-drive and stable actuator displacement 40% greater than a parallel plate type actuator. The angular electrostatic microactuator using skewed SEA scheme was designed and fabricated using SoG process.

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유리의 미세 구멍 가공을 위한 구리 전극군 제작 및 전기 화학 방전 가공 시험 (Fabrication of Copper Electrode Array and Test of Electrochemical Discharge Machining for Glass Drilling)

  • 정주명;심우영;정옥찬;양상식
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2003년도 추계학술대회 논문집 전기물성,응용부문
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    • pp.297-299
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    • 2003
  • In this paper, we present the fabrication of copper electrode array and test of electrochemical discharge machining for the fabrication of microholes on Borofloat33 glass. Copper electrode array is fabricated by the bonding of silicon upper substrate and lower substrate and copper electroplate. The silicon upper electrode having microholes fabricated by ICP-RIE is the mold of copper electroplate. The lower substrate is used as the seed layer for copper electroplate after Au - Au thermocompression bonding with the upper substrate.

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2차원 전기비저항 탐사를 위한 변형된 전극배열법에 관한 연구 (A Study on the Modified Electrode Arrays in Two-Dimensional Resistivity Survey)

  • 김정호;이명종;송윤호;정승환
    • 지구물리와물리탐사
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    • 제4권3호
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    • pp.59-69
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    • 2001
  • 2차원 전기비저항 탐사에 일반적으로 사용되는 전극배열들의 단점을 보완하기 위해 단극과 쌍극자를 사용하는 기존의 전극배열로부터 5 종류의 변형된 전극배열법을 제안하였다. 변형된 단극 배열법은 원거리 접지전극이 필요한 단극 배열법의 비효율성을 보완하기 위한 전극배열법이다. 4 종류의 쌍극자를 이용하는 변형된 전극배열법은 쌍극자 또는 단극-쌍극자 배열이 갖는 문제점, 즉 낮은 측정값에 의한 낮은 신호대 잡음비를 개선하여 높은 측정값의 획득이 가능하도록 설계하였다. 수치 모델링과 2차원 역산을 이용한 수치 실험을 수행하였으며, 전기적 잡음에 의한 영향과 분해능에 대하여 고찰하여 본 논문에서 제안된 전극배열의 효용성을 입증하였다.

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다전극 배열을 이용한 콘크리트 매립 철근의 위치탐사 (Probing of Steel Bar Location inside Concrete using Multi-electrode Array)

  • 이형우;임홍철
    • 한국콘크리트학회:학술대회논문집
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    • 한국콘크리트학회 2003년도 가을 학술발표회 논문집
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    • pp.663-666
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    • 2003
  • Using numerical analysis modeling of Multi-electrode Array that could be applied to the corrosion state measurement of a reinforcing steel bar in concrete, the steel bar location inside concrete can be probed by the investigation of the change of the measured impedance from concrete surface determined by the electrical impedance of interface between the steel bar and concrete, the electrical resistivity of concrete, the array of electrodes and the relative location and diameter of the steel bar.

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혼합배열을 사용하는 시추공간 전기비저항 탐사 (The Crosshole Resistivity Method Using the Mixed Array)

  • 조인기;한성훈;김기주
    • 지구물리와물리탐사
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    • 제5권4호
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    • pp.250-256
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    • 2002
  • 전기비저항 토모그래피는 지하의 전기비저항 분포를 영상화할 수 있는 매우 중요한 정밀 물리탐사법으로 지반조사 및 환경 오염대의 조사에 널리 사용되고 있다. 전기비저항 토모그래피 탐사의 경우 다양한 전극배열법이 사용될 수 있으며 각 배열법은 나름대로의 장단점을 가지고 있다. 예를 들어 단극배열의 경우에는 신호대 잡음비는 높으나 분해능이 벌어지며, 쌍극자배열의 경우에는 분해능은 높지만 신호대 잡음비가 너무 낮다. 단극-쌍극자 배열의 경우에는 중간정도의 분해능과 신호대 잡음비를 갖는다. 최근 개발된 변형된 단극-쌍극자 배열의 경우에는 단극-쌍극자 배열 수준의 신호대 잡음비와 분해능을 갖는다. 그러나 단극배열을 제외한 이들 전극배열법은 전류 및 전위 전극의 위치에 따라서는 겉보기 비저항이 발산할 수도 있다는 단점을 갖는다. 또한 단극배열의 경우에는 측정된 겉보기 비저항이 이상체의 전기비저항을 그대로 반영하지 못한다는 단점이 있다. 본 연구에서는 전류전극과 전위전극의 상대적인 위치에 따라 단극-쌍극자 배열과 변형된 단극-쌍극자 배열을 혼용하는 소위 혼합배열이라는 새로운 전극배열법을 제안하고자 한다. 이 새로운 전극배열법은 신호대 잡음비 및 분해능은 단극-쌍극자 배열의 수준을 유지하며, 측정 시추공상에서 겉보기 비저항이 발산하지 않는 특성을 갖는다. 또한 측정되는 겉보기 비저항은 항상 이상체의 전기비저항을 잘 반영한다.

Amperometric Morphine Detection Using Pt-Co Alloy Nanowire Array-modified Electrode

  • Tao, Manlan;Xu, Feng;Li, Yueting;Xu, Quanqing;Chang, Yanbing;Wu, Zaisheng;Yang, Yun-Hui
    • Bulletin of the Korean Chemical Society
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    • 제31권7호
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    • pp.1968-1972
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    • 2010
  • Pt-Co alloy nanowire array was directly synthesized by electrochemical deposition with polycarbonate template at -1.0V and subsequent chemical etching of the template. The use of Pt-Co alloy nanowire array-modified electrode (Pt-Co NAE) for the determination of morphine (MO) is described. The morphology of the Pt-Co alloy nanowire array has been investigated by scanning electron microscopy (SEM) and energy disperse X-ray spectroscopy (EDS) analysis), respectively. The resulting Pt-Co NAE offered a linear amperometric response for morphine ranging from $2.35\times10^{-5}$ to $2.39\times10^{-3}$ M with a detection limit of $7.83\times10^{-6}$ M at optimum conditions. This sensor displayed high sensitivity and long-term stability.