• 대한인간공학회지
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• 제29권6호
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• pp.853-860
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• 2010

This study investigated differences in blood oxygen saturation($SpO_2$) and heart rate(HR) according to flow rate, gender, and phase in males and females in their 60s when the supply of 93% highly concentrated oxygen administration was changed (1L/min, 3L/min, and 5L/min). It recruited totally 20 elderly subjects including 10 males($68.0{\pm}2.6$ years) and 10 females ($65.5{\pm}3.1$ years). The experiment consisted of three phages of Rest 1(5 min), Hyperoxia(10 min), and Rest 2(10 min), and $SpO_2$[%] and HR[bpm] were measured during all phages. $SpO_2$ was higher in Hyperoxia phase supplied with highly concentrated oxygen than in Rest phases. Higher flow rate was associated with more increase in $SpO_2$. HR was reduced in Hyperoxia phase compared to Rest phases. More supply of highly concentrated oxygen was associated with more decrease of HR. However, there were no differences in both $SpO_2$ and HR according to gender.

• 대한임상검사과학회지
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• 제53권3호
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• pp.208-216
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• 2021

코로나바이러스 감염증 19는 중증급성호흡기증후군 코로나바이러스 2의 명칭에서 명명되었다. 이 연구는 코로나바이러스 감염증 19 환자의 신기능 상태를 조사하는 것을 목적으로 하였다. 본 연구는 경기도 남부 한 병원에서 코로나바이러스 감염증 19로 입원한 649명 환자를 대상으로 하였다. 이번 연구에서 검토한 코로나바이러스 감염증 19 환자의 혈액요소질소와 크레아티닌은 증가된 패턴을 보였다. 본 연구의 대상자 중 남성의 혈액요소질소는 정상 범위보다 높았다. 특히 60대, 80대 이상에서 높게 나타났고, 크레아티닌 수치도 비슷하게 나타났다. 이 연구에서 환자의 전해질 검사는 정상 범위에서 벗어나는 결과는 관찰되지 않았다. 이 연구의 대상에서 80세 이상의 남성은 60 mL/min/1.73 m² 이하의 만성신장질환 역학협력 사구체여과율을 나타냈다. 최근 연구에 따르면 COVID-19의 일부 심각한 사례는 코로나바이러스에 감염되기 전에 기저 신기능의 문제가 없었던 사람들에게도 콩팥 손상의 징후를 보이고 있다. 따라서 여러 지표 평가의 신기능 검사는 검사결과의 검토는 코로나19 환자의 비정상 신기능 발견에 도움이 될 수 있다.

• 한국식생활문화학회지
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• 제22권1호
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• pp.127-139
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• 2007

This research was peformed to investigate the anthropometric data, blood profiles, and nutrient intakes of elderly persons living in a rural area. The subjects were 67 undernourished people who participated in follow-up nutrition intervention programs for9 weeks. Anthropometric data showed that the mean heights and weights in the management group were 157.6 cm and 59.1 kg, respectively, for the males and 152.6 cm and 51.0 kg, respectively, for the females. The mean BMIs of the management group were 23.8 kg/m$^2$ in the males and 22.4 kg/m$^2$ in the females. The total cholesterol, HDL-cholesterol, and albumin levels of the subjects were 181.7-191.4mg/dL, 48.3-53.0mg/dL, and 3.85-4.00g/dL, respectively. Energy, ash, P, Na, vitamin B$_1$, vitamin B$_2$, vitamin B$_6$, and niacin increased significantly after intervention for the management group. The mINQ, however, did not significantly increase after intervention. Also after intervention, there was no significant difference in mINQ between the management group and the comparison group. MAR (14) in the management group was significantly increased from 0.62${\pm}$0.2 before intervention to 0.68${\pm}$0.2 after intervention (p=0.022), and it was significantly different between the management group and the comparison group (p=0.017). MAR (8) in the management group was not significantly different (p=0.915) before and after intervention. However, MAR (8) between the management group and the comparison group did show a significant difference (p=0.031). MAR (3) in the management group was significantly increased from 0.48${\pm}$0.2 before intervention to 0.55${\pm}$0.2 after intervention (p=0.045), however, MAR (3) was not significantly different between the management group and the comparison group (p=0.093). For the probability of nutrient insufficiency, in the management group the probability of nutrient values below the EAR (except for Fe) decreased after intervention compared to before intervention. On the other hand, the probabilities of values above the RI, or EAR${\sim}$RI, were increased

• 동의신경정신과학회지
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• 제26권1호
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• pp.39-48
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• 2015

Objectives: This study was conducted to analyze the hwa-byung, self-perceived health, life-stress, social support, depression, and factors affecting on suicidal ideation in community dwelling elders. Methods: This study was a cross-sectional descriptive study. The subjects were 165 elderly in I city. The data was collected from November $21^{st}$ to December $5^{th}$ of 2014 by using structured questionnaire. T-test, Pearson's correlation coefficients, and stepwise multiple regression were performed by SPSS/PC 17.0. Results: There were more females than males in hwa-byung (t=.-3.068, p=.003). In the visit parent, more than once a month was a significantly higher in social support (t=.3.333, p=.001). Hwa-byung (t=.-2.577, p=.011), life-stress (t=.-3.800, p=.001), depression (t=.-2.776, p=.006), and suicidal ideation (t=.-4.316, p<.001) were shown to be high in the elders with lower level of living. Subjects with health insurance had high self-perceived health (t=-3.800, p=.001) and low hwa-byung (t=-4.102, p<.001), life-stress (t=-4.482, p<.001), depression (t=-5.296, p<.001), and suicidal ideation (t=.-2.152, p=.036), according to the type of insurance. In the correlation, sleeping hours (r=-.180, p=.020), self-perceived health (r=-.364, p,.001), and suicidal ideation had negative correlation; hwa-byung (r=.404, p<.001), life-stress (r=.300, p<.001), social support (r=-.310, p<.001), depression (r=.423, p<.001) and suicidal ideation had positive correlation. Factors affecting the suicidal ideation in community dwelling elders were depression (${\beta}$=.42, p<.001), hwa-byung (${\beta}$=.23, p=.004), social support (${\beta}$=-.18, p=.012), and level of living (${\beta}$=.24, p=.001). Discussion: For the prevention of elderly suicide, it is necessary to care for psychosocial status and solve economic difficulties through social support.

• Asian Pacific Journal of Cancer Prevention
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• 제17권1호
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• pp.395-399
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• 2016

Background: Whether ambient exposure to environmental pollutants leads to hematopoietic malignancies such as multiple myeloma (MM) remains to be ascertained. Therefore, we aimed to investigate the immunotyping distribution of serum monoclonal paraprotein and the environmental influence on MM and monoclonal gammopathy of uncertain significance (MGUS) in the Taiwanese population. Materials and Methods: Serum protein electrophoresis with immunosubtraction by the capillary zone electrophoresis method was performed as primary screening for MM and MGUS. Clinical, pathological, and residence data of patients were also obtained. Results: From August, 2013 to June, 2015, a total of 327 patients underwent serum protein electrophoresis with immunosubtraction. Among these, 281 demonstrated no remarkable findings or non-malignant oligoclonal gammopathy, 23 were detected to have MGUS, 18 were identified as MM, and a further 5 were found as other malignancies. The most frequent immunotyping distribution of serum monoclonal paraprotein was IgG kappa (54.3%, n=25), followed by IgA lambda (15.2%, n=7) and IgG lambda (10.9%, n=5) in subjects with gammopathy. Additionally, it was shown that the elderly (OR: 4.61, 95% CI: 1.88-11.30, P<0.01) and males (OR: 2.04, 95% CI: 1.04-4.02, P=0.04) had significantly higher risk of developing MM and MGUS. There was no obvious impact of environmental factors on the health risk of MM and MGUS evolution (OR: 0.77, 95% CI: 0.40-1.50, P=0.49). Conclusions: The most frequent immunotyping distribution of serum monoclonal paraprotein included IgG kappa, IgA lambda and IgG lambda in MM and MGUS in the Taiwanese population. The elderly and male subjects are at significantly higher risk of MM and MGUS development, but there was no obvious impact of environmental factors on risk.

• Tuberculosis and Respiratory Diseases
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• 제64권5호
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• pp.374-378
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• 2008

혈관육종은 매우 드문 악성종양으로 고령 남자의 두피나 얼굴에 주로 발생하며, 폐로 전이되는 경우가 있다. 폐전이의 경우 객혈, 기흉 등의 호흡기계 증상을 일으킬 수 있다. 저자들은 혈관육종의 폐전이가 낭성변화를 일으켜 기흉 및 혈흉을 초래한 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

• 한국노년학
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• 제40권1호
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• pp.33-49
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• 2020

본 연구는 사회적 배제의 잠재유형을 구분하고 노후의 경제적 불안에 미치는 영향을 실증적으로 분석하였다. 또한 주관적 계층의식에 따라 그 영향력이 달라지는지를 함께 살펴보고자 하였다. 이를 위해 2016년 한국종합사회조사(KGSS) 14차 자료를 사용하여, 조사 당시 기준 만 18세의 성인남녀 1,041명의 응답지를 분석하였다. STATA14와 MPLUS 7 통계프로그램을 이용하여 기술통계분석과 t-test, 잠재계층분석(LCA), 잠재집단에 대한 다항로지스틱분석을 실시하였다. 마지막으로 다중회귀분석을 실시하여 변수 간 영향관계 및 조절 효과를 확인하였다. 연구결과 사회적 배제의 유형은 3집단으로 나타났으며, 사회활동배제집단(49.3%), 다차원적 배제집단(30.9%), 사회 활동 적극집단(19.7%)의 순으로 나타났다. 사회활동배제집단은 경제, 고용, 건강 배제의 가능성이 가장 낮지만, 공식/비공식 사회활동의 배제가 두드러진 집단이며, 다차원적 배제집단은 모든 영역에서 배제를 경험할 가능성이 50% 이상인 집단으로 나타났다. 사회활동 적극집단은 비공식 사회활동에 매우 적극적으로 참여하는 것이 특징인 집단이다. 다항로지스틱 분석결과 사회활동배제집단은 다른 집단에 비해 청년층이 많이 포함되었으며, 다차원적 배제집단에는 배우자가 없는 여성노인이 많이 포함되어 있는 것으로 나타났다. 마지막으로 다중회귀분석 결과 사회적 배제 유형은 주관적 계층의식과 상호작용하여 노후의 경제적 불안에 영향을 미치는 것으로 나타났다. 이러한 연구결과를 바탕으로 노후의 경제적 불안을 예방하기 위한 정책적·실천적 방안을 제언하였다.

• 대한임상검사과학회지
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• 제54권2호
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• pp.95-102
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• 2022

Lp(a)와 이상지질혈증의 관계가 명확하지 않아, 본 연구는 60세 이상 노인 환자를 대상으로 Lp(a)와 이상지질혈증의 관계를 조사하고자 하였다. 2014년 1월 1일부터 2020년 12월 31일까지 7년간 한 종합병원을 내원한 60세 이상 노인 중 나이, 성별, BMI, Lp(a), LDL-C, TG, HDL-C, hs-CRP, HbA1c, 지질강하제 복용 여부, 이상지질혈증 의사진단여부 등의 기록이 있는 2,580명을 최종 분석대상자로 선정하였다. Lp(a)와의 상관성은 hs-CRP (r=0.138), LDL-C (r=0.097), HDL-C (r=-0.089), TG (r=-0.073), 나이(r=0.072) 등이 유의하였으며, BMI, HbA1c는 유의하지 않았다. 변수들을 보정한 Lp(a)와 LDL-C의 편상관관계는 남성그룹에서만 유의하였다(r=0.158, P<0.001). 본 연구에서 이상지질혈증에 대한 Lp(a)의 4사분위의 교차비(교차비=1.376, 95% 신뢰구간=1.038~1.822)가 유의하게 나타남으로써 지질강하제 복용으로도 1차 표적인 LDL-C 수준을 낮추지 못했을 때, 2차적으로 고려해봐야 할 여러 요소 중 Lp(a)도 포함되어야 한다고 판단된다. 성별, 연령, 지질강하제 복용 여부 등에 따른 다양한 지질인자들에 대한 연구들이 필요하다고 사료된다.

• 생물정신의학
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• 제6권1호
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• pp.102-110
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• 1999

Objectives : The alcohol dependence in elderly people has been prevalent because of increase in geriatric population. However, it is difficult to find out alcohol dependence in the aged, because they have less specific clinical features as compared with adult alcoholics. The aims of this study were to screen alcohol dependence among elderly Koreans and to know the clinical characteristics of Korean delerly alcoholics. Methods : The questionnaires translated into Korean such as Michigan Alcoholism Screening Test(MAST-K), the Brief MAST and the MAST-Geriatirc Version (MAST-KG) were used to screen alcohol dependence in the elderly alcoholic inpatients aged over 60(N=43), adult alcoholic inpatients within 20-59 Yrs of age(N=60), which were compared with age matched normal healthy aged(N=18) or adult controls(N=45). The demographic data such as sex, age, education, occupation, socioeconomic status, marital status, numbers of children, dwelling and religion as well as alcohol history such as duration of alcohol drinking, onset age, family history, impulsivity, somatic illness and motivation were also obtained to identify characteristic features of Korean aged alcoholics by structured interviews. Results : 1) The aged alcoholics had the charateristic features of more in males, lower age, low education levels, more in blue-collar workers, lower socioeconomic class, more in single, few babies, more living alone, having no religion without statistical significance. 2) The onset age of alcohol dependence was significantly higher in the aged alcoholics($45.3{\pm}13.6Yrs$) than in the adult alcoholics($27.7{\pm}8.7Yrs$)(p<0.0001). The duration of problematic alcohol drinking was significantly longer in the aged alcoholics($22.0{\pm}15.1Yrs$) than in adult alcoholics($14.2{\pm}8.4Yrs$)(p<0.01). Otherwise, there were no significant difference between aged and adult alcoholics in the family history, imulsivity, somatic illness and motivation. 3) The mean score of the MAST-K was significantly higher in the aged alcoholics($20.6{\pm}5.4$) than in the normal aged($6.7{\pm}4.4$)(p<0.0001), which was significantly lower than in the adult alcoholics($26.2{\pm}8.0$) and in normal adult controls($9.5{\pm}3.2$)(p<0.05). The mean score of the Brief MAST was significantly lower in the aged alcoholics($9.3{\pm}3.5$) than in the adult alcoholics($14.5{\pm}6.6$)(p<0.0001). The mean score of the MAST-KG was significantly higher in the aged alcoholics($10.6{\pm}3.5$) than in the normal aged($4.8{\pm}4.3$)(p<0.0001). The former was significantly lower than in the adult alcoholics($12.9{\pm}4.3$)(p<0.005), and the mean score was $4.5{\pm}2.8$ in normal adult controls. 4) The items which showed statistically significant differences between aged alcoholics and normal aged controls could be found in 10 items of the MAST-K(items 2, 3, 4, 5, 11, 14, 17, 21, 22 and 23), 2 items of the Brief MAST(items 2 and 9), and 7 items of the MAST-KG(items 6, 13, 18, 19, 22, 23 and 24)(p<0.01). Conclusions : The scores of the MAST-K, the Brief MAST and the MAST-KG were significantly lower in the aged alcoholics than those in the adult alcoholics (p<0.05). The statistically significant differences between aged alcoholics and normal aged controls could be found in 10 items of the MAST-K, 2 items of the Brief MAST and 7 items of the MAST-KG. Therefore, a briefer rating scales around 10 items are needed to screen alcohol dependence among Korean elderly people.

• Clinics in Shoulder and Elbow
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• 제13권1호
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• pp.20-26
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• 2010

목적: 중 장년층에서 견관절 탈구 후 발생한 회전근 개 파열의 임상양상을 분석하고, 수술적 치료의 결과를 알아보고자 한다. 대상 및 방법: 2004년 10월에서 2008년 10월까지 견관절 탈구와 회전근 개 파열이 동반되어 수술적 치료를 시행한 50세 이상의 환자 19명을 대상으로 하였다. 남자 7명과 여자 12명으로, 평균 나이는 64.7세 (50~78세)였고, 추시 기간은 평균 22개월 (8~56개월) 이었다. 탈구의 횟수, 회전근 개 파열의 크기, 견관절 내 Bankart 병변, 수술까지의 시간 등을 조사하였고, 수술 전, 후의 ASES 점수, UCLA점수, SST 점수 및 운동범위를 측정하여 수술 후의 임상결과 및 결과에 미치는 인자를 알아 보고자 하였다. 결과: ASES 점수는 술 전 30.2점 (${\pm}20.7$)에서 술 후 72.3점 (${\pm}20.3$)으로, UCLA shoulder rating scale은 12.9점 (${\pm}5.2$)에서 26.5점 (${\pm}7.0$)으로. SST 점수는 2.4점 (${\pm}3.3$)에서 7.3점(${\pm}4.2$)으로 향상되었다. 운동 범위는 술 전 전방 거상, 외전, 외회전 및 내회전이 각각 110.8도 (${\pm}39.3$), 107.7도 (${\pm}40$), 22.5도 (${\pm}17.6$)와 L5 수준에서 술 후 전방 거상, 외전, 외회전 및 내회전이 각각 153.6도 (${\pm}20.6$), 152.1도 (${\pm}20.8$), 36.4도 (${\pm}22.7$)와 L1 수준으로 통계학적으로 의미 있게 향상되었다. 나이와 Bankart 병변의 유무, 탈구 횟수는 수술 후의 결과와 관련이 없는 것으로 관찰 되었다. 그러나 파열이 클 수록 임상결과는 좋지 않았고, 수상 후 수술까지의 기간과 술 후 UCLA 점수와 술 후 SST 점수가 통계학적인 의미가 있는 것으로 관찰되었다 (p=0.039, 0.038). 결론: 중 장년 이후에 견관절 탈구 발생시 조기에 회전근 개 파열에 대한 검사가 필요할 것으로 생각된다. 또한 회전근 개 파열이 동반된 경우, 조기에 회전근 개 봉합을 시행하는 것이 더 좋은 결과를 얻을 수 있다.