Background: Malignant mesothelioma (MM) is an aggressive tumor of mesothelial surfaces. Previous studies have observed an association between ABO blood groups and risk of certain malignancies, including pancreatic and gastric cancer; however, no information on any association with MM risk is available. The aim of this study was to investigate possible associations amoong MM clinicopathological features and ABO blood groups and Rh factor. Materials and Methods: In 252 patients with MM, the ABO blood group and Rh factor were examined and compared with the control group of 3,022,883 healthy volunteer blood donors of Turkish Red Crescent between 2004 and 2011. The relationship of blood groups with various clinicopathological features were also evaluated in the patient group. Results: The median age was 55 (range: 27-86) and 61.5% of patients were male. While 82.8% of patients had a history of exposure to asbestos, 60.7% of patients had a smoking history. Epithelioid (65.1%) was the most common histology and 18.7% of patients had mixed histology. Overall, the ABO blood group distribution of the 252 patients with MM was comparable with the general population. The median overall survival (OS) was 14 months (95% confidence interval, 11.3-16.6 months). The median OS for A, B, AB, and O were 11, 15, 16, and 15 months respectively (p=0.396). First line chemotherapy was administered to 118 patients. The median OS of patients on pemetrexed or gemcitabine was longer than patient who was not administered chemotherapy [17 months (95%CI, 11.7-22.2) vs. 9 months (95%CI, 6.9-11.0); p<0.001]. Conclusions: The results of this study suggest that patients with MM can benefit from treatment with pemetrexed or gemcitabine in combination with cisplatin. We did not observe a statistically significant association between ABO blood group and risk of MM.
Journal of the Computational Structural Engineering Institute of Korea
/
v.30
no.3
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pp.239-248
/
2017
According to the structure, solenoid valve can be categorized as spool valve or poppet valve. While various research on spool valve which has simple structure and fine susceptibility to contamination has been conducted, poppet valve which has less susceptibility to contamination and advantage in a long time operation still need much research because of its complicated structure. In order to design the poppet valve, various parameters such as the diameter of the poppet, the angle of the poppet, the diameter of the disk, the spring stiffness, the spring preload and flow path structure should be considered. Conventional studies on poppet valve usually take only one design parameters and did not much focused on the effect of the parameters on flow characteristics. In this paper, the change of the flow characteristics according to the design parameters of the poppet valve for 3/2Way solenoid valve is analyzed. The previous studies and the results of initial model analysis was referred for the selection of the design parameters. The effects of design parameters on maximum pressure, minimum pressure, and pressure drop was examined using analysis of means(ANOM).
Background: The aim of this study was to investigate demographic features, dietary habits, and some possible risk factors for being susceptible to breast cancer in Iranian women. Materials and Methods: A study of dietary habits and breast cancer was conducted among 53 Iranian women with histological confirmed disease and 40 matched controls. A dietary habits questionnaire was used to evaluate the pattern of selected food intakes. The risk of cancer was analyzed after adjustment for confounding factors. Age, weight, body mass index (BMI), waist circumference, educational status, parity, lactation, marital status, menopause, history of estrogen therapy, and family history of breast disease or cancer were assessed among participants. Special attention was given to the relationship between consumption of high fat meat, milk, yogurt and cheese as well use of frying oils for frying foods, use of olive/liquid oils for cooking, removing fat from meat and poultry, removing chicken skin and not use of mayonnaise as salad dressing and the risk of breast cancer. Moreover, salad, vegetable and fruit consumption, and eating outdoors owere investigated. Results: Our results revealed significant lower education and higher BMI and waist circumference levels in patients with breast cancer. There was significantly increased breast cancer risk in overweight women in comparison with normal weight (OR=2.91, 95%CI 1.24 to 6.82). High intake of fat dairy products including milk and cheese was found to be a statistically significant factor for increasing breast cancer risk in models adjusting for age, BMI and education. Use of olive/liquid oils for cooking and avoidance of mayonnaise as salad dressing are related to lower risk of breast cancer. The frequency of vegetable and fruit consumption was significantly lower in patients with breast cancer compared to healthy women. Conclusions: Dietary habits might be risk factors for breast cancer among Iranian women. Adoption of a prudent diet could be an appropriate strategy for preventing breast cancer.
Journal of Korean Home Economics Education Association
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v.22
no.2
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pp.81-99
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2010
This study was motivated by the fact that the educational curriculum needs revising as the contemporary society undergoes dramatic changes; this change demonstrates that Korea society now turns into a multicultural community. In this vein, this study aims to examine how the national Home economics curriculum (revised in 2007) incorporated the essence of multicultural education program and that of international understanding program into the coursebook, and to suggest which part of the coursebook needs revising to enhance its validity. To attain this goal, this research was conducted to analyze how two programs are implemented in secondary school, and to propose how those programs should be developed to address the immediate needs of the current society. To illustrate, this study examines a variety of theories and methodology on how multicultural education program should be implemented along with the current situation of Korea society. In addition, quantitative research was conducted to acquire empirical data from 6 coursebooks the frequencies of statements and visual aids that are considered to be directly reflect the essence of two programs. The results demonstrate that two programs are relegated into a lesser position compared to other programs; furthermore, they lack materials to deepen students' understanding about multicultural society and international relations. Therefore, the considerable revision needs to be conducted to embrace the essence of multicultural society and international understanding programs, and sensitize students to the immediate needs of the current society.
Journal of Korean Home Economics Education Association
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v.29
no.2
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pp.85-111
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2017
The purpose of this study was to examine the need of the ideal human being and to establish ideal desirable state of affairs in the ideal portrait of a human being for pursuing in the home economics education. This study analyzed the deducted issue from the discussion about the human being in the educational research through the national curriculum and literature review. The desirable state of affairs established in this research are (1) it needs to reflect the feasibility aspect for actual implementation, (2) it needs to consider the contextual subject aspect, and (3) the curriculum view containing the philosophy of the subject, that is, critical science perspective shall be reflected on the desirable human being. The ideal portrait of a human being was stated, in the individual family, society nation, cultur e world according to subcategories. In addition, the stated ideal portrait of a human being was modified through expert consultations. The proposal was reexamined for the validity of the statement and restated as a comprehensive statement of an ideal portrait of a human being that included a restatement of the three areas. An ideal portrait of a human being pursuing in home economics education from a core value of curriculum stated as 'a person who has solved the practical problem actively'.
In this study, Private investigation in South Korea, while gone through so far of politics, the process of social change, a positive feature, without evolve, insufficient growth and security services of the business burden of national judicial institutions, detective industry international of the negative vicious circle, such as the acquisition of drop and expedient information of competitiveness is continuously induced it is a reality. It is, therefore, to the proposal, such as the following. First, it must be able to use the term "detective". Secondly, in order to verify the validity of this system, after introducing the first private sphere, in accordance with the stepwise its necessity, it is desirable to extend the operational range of the public area. Third, to have a country of qualification to private research workers, will be managed directly from the country is ideal. Fourth, we must also seek plan to specialize the designated educational institution as a commissioned education institution to institution with a faculty and facilities that are specialized. Fifth, the National Police Agency must manage and supervise the private investigation business. Sixth, the legislative form to amend the current security law, as a kind of private security, must be introduced by adding a private trillion business. Therefore, in order to complement the limitation of such studies, additional subsequent research has if it is not carried out.
Journal of The Korean Association For Science Education
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v.24
no.3
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pp.468-480
/
2004
It has been criticized that there are discrepancy between 'general statements' of the curriculum and subject-matter curricula. The possible reasons for this are as follows: The developers of the general statements were educational curriculum specialists. These specialists were not good enough to develop general statements and guidelines of subject matter curricula reflecting the characteristics of science contents, to examine developed science curriculum, and to give feedback to science curriculum developers. Under the present curriculum developing system where curriculum is developed in ten months or less by the research team commissioned unpredictably and imminently, it might be difficult to develop valid and precise science curriculum reflecting the purport of the general statements and teachers' needs. The inadequacy of these curriculum development processes resulted in (1) inconsistent statement about the school year to be applied to differentiated curriculum, (2) abstract and ambiguous stating about the characteristics, teaching-learning and assessment guidelines of enrichment activities, and (3) failure to reduce science contents to a reasonable level. Therefore curriculum development centers should be designated in advance to do basic research at ordinary times, and organized into a cooperative system among them. Two years or more of developing time and wider participation of scientists are recommended to develop more valid and precise science curriculum. In addition, commentaries on science curriculum should be published before textbook writing begins.
Using a national survey data conducted by the Beautiful Foundation, this study attempts to examine the bilateral relationships between philanthropic effort and social trust and between volunteering effort and social trust by using simultaneous equation model. This study also attempts to examine the socialization effect and intergenerational effect of philanthropy and volunteering in family, school, and community. This study found that both philanthropic effort and volunteering effort have a bilateral relationship with social trust. The bilateral relationship between giving and volunteering and social trust suggests that not only can social trust affect the increase of giving and volunteering but giving and volunteering can also influence social trust. Thus, by strengthening trust and facilitating giving and volunteering, we can construct and promote culture of sharing in our society. On the other hand, in the analysis on individual's educational experience in giving and volunteering during school years and individual's family experience (parental practice) in giving and volunteering during school years, it was found that family experience was statistically significant on philanthropic effort and volunteering effort. The result suggests that considering the validity of intergenerational effect in giving and volunteering, it is strategically vital for our society to facilitate and promote family practice in giving and volunteering throughout diverse programs and social marketing. Although this study has a limitation due to the limitedness of the original data, it made a significant contribution to advancing knowledge on the relationship between giving and volunteering and social trust by using elaborate analysis methods. This study emphasizes the necessity of continuous research; more advanced and systematic study based on a more elaborate model and solid data such panel data should be continued for a better understanding of philanthropic and volunteering behavior that can be an important soil for the development of nonprofit human service organizations. Finally, based on the results of the study, this study discusses research directions and practical implications to deepen and broaden the culture of sharing in Korea.
Park, Hey-Jeong;Yi, Chung-Hwi;Cho, Sang-Hyun;Kwon, Hyuk-Cheol
Physical Therapy Korea
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v.7
no.1
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pp.1-21
/
2000
The purposes of this study were to research the current state of evaluation of children with delayed development and cerebral palsy and determine pediatric physical therapists' knowledge of assessment tools and their use. The subjects were 130 pediatric physical therapists (general hospitals, university-related hospitals, rehabilitation centers, etc.). Data was obtained from August 24, 1999 to October 18, 1999 by means of a survey questionnaire. The results were as follows: 1. The current state of pediatric physical therapist evaluation of children with delayed development and cerebral palsy. 1) Tools used to assess functional areas of children with cerebral palsy were: subjective description format-128 (47.1%); the GMFM-58 (21.3%); facility-generated tool-51 (18.8%); and DDST-15 (5.5%). 2) Tools used to assess developmentally delayed children were: subjective description format-121 (50.6%); the GMFM-43 (18.0%); facility-generated tool-41 (17.2%); and DDS T-14 (5.9%). 3) After their college or university study, therapists who had attended lectures on evaluation were 113 (86.9%); 13 (10.0%) therapists had not attended any lectures on evaluation 2. Test scores of physical therapists' professional knowledge of evaluation procedures: high (more than 36 points)-74 (56.9%); moderate (18~35 points)-39 (30.0%); and low (below 17 points)-none. 1) For therapists treating cerebral palsied children, 73 (65.2%) were in the high range, 39 (34.8%) were in the moderate range and none were in the low range. 2) For therapists treating children with delayed development, 71 (65.7%) were in the high range, 37 (34.3%) were in the moderate range and none were in the low range. Although the general degree of professional knowledge of evaluation was quite high, there was a lack of variety in the assessment tools used With a large number of therapists depending on subjective description. Possible reasons for the low rate of objective asses sment tool use: 1) Poor clinical environment: too many clients and lirnited treatment time. 2) Lack of any medical insurance fee category for specific assessment tools. 3) Lack of continuing education opportunities in pediatric evaluation skills during or after either college-based (3 year) or university-based (4 year) education programs. Based on the study results, provision of more extended educational opportunities would promote the use of a greater variety of objective assessment tools by pediatric physical therapists.
Journal of The Korean Association of Information Education
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v.5
no.2
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pp.240-257
/
2001
Although many attempts have been made to use the Internet for educational purposes, not many attempts have achieved their goals. Such failure is mainly due to the lack of understanding on the way to use the Internet. The goal of this research is to investigate the potentiality of the Project-Based Learning approach using the Internet(NetPBL) and the ways to utilize the NetPBL. The NetPBL can be utilized through various activities such as keypals, mentoring, use of resources, cooperative learning, publishing, survey and data analysis, cooperative problem solving, simulation, and social action. Such diversity of the NetPBL can create a problem-based, context-based and learner-centered environment, which takes various types of the Internet use. In spite of such potentiality, little is known on how to implement the NetPBL. On this point, this research attempts to synthesize instructional strategies to implement the NetPBL at the macro and the micro level. At the macro level, instructional process is divided into four steps such as plan, preparation, implementation and closure, and some instructional suggestions are made for each step. At the micro level, detailed instructional strategies are suggested for the facilitation of self-directed learning and cooperative learning.
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