• Asian Pacific Journal of Cancer Prevention
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• v.13 no.10
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• pp.4855-4860
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• 2012

Since cancer is one of the leading causes of death worldwide, and there is an urgent need to find better treatment. In recent years remarkable progress has been made towards the understanding of proposed hallmarks of cancer development and treatment. Treatment modalities comprise radiation therapy, surgery, chemotherapy, immunotherapy and hormonal therapy. Currently, the use of chemotherapeutics remains the predominant option for clinical control. However, one of the major problems with successful cancer therapy using chemotherapeutics is that patients often do not respond or eventually develop resistance after initial treatment. This has led to the increased use of anticancer drugs developed from natural resources. The biodiversity of venoms and toxins makes them a unique source from which novel therapeutics may be developed. In this review, the anticancer potential of snake venom is discussed. Some of the included molecules are under clinical trial and may find application for anticancer drug development in the near future.

• Proceedings of the Korean Vacuum Society Conference
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• 2014.02a
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• pp.176.1-176.1
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• 2014

Graphene has attracted an increasing attention due to its extraordinary electronic, mechanical, and thermal properties. Especially, the two dimensional (2D) sheet of graphene with an extremely high surface to volume ratio has a great potential in the preparation of multifunctional nanomaterials, as 2D supports to host metal nanoparticles (NPs). Copper oxide is widely used in various areas as antifouling paint, p-type semiconductor, dry cell batteries, and catalysts. Although the copper oxide(II) has been well known for efficient catalyst in C-N cross-coupling reaction, copper oxide(I) has not been highlighted. In this research, CuO and Cu2O nanoparticles (NPs) dispersed on the surface of grapehene oxide (GO) have been synthesized by impregnation method and their morphological and electronic structures have been systemically investigated using TEM, XRD, and XAFS. We demonstrate that both CuO and Cu2O on graphene presents efficient catalytic performance toward C-N cross coupling reaction. The detailed structural difference between CuO and Cu2O NPs and their effect on catalytic performance are discussed.

• Journal of the Korean Society of Earth Science Education
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• v.6 no.1
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• pp.78-86
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• 2013

The purpose of this study is to analyze the effects of the Project based STEAM program on primary students' Problem solving process and creative personality. Based on the concept of project based learning and STEAM derived from a literature review, a learning program has been developed and applied to 28 elementary 4-6th students. Problem Solving Process and Creative personality tests were conducted before and after Project based STEAM program lessons. The results of this study are as follows. (1)Project-based STEAM was affected all components of problem solving process. (2) Project-based STEAM was affected all eight components of creative personality positively, (3) after using Project-based STEAM was good reaction by students. As a result, the elementary science class with Project-based STEAM had problem solving process for positive educational effect and creative personality. it means the science class with creative personality has potential possibilities and value to develop problem solving process and creative personality.

• Research in Mathematical Education
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• v.16 no.4
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• pp.207-216
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• 2012

Through quantitative video analysis of four algebra classes and statistical analysis of various types of teacher evaluation behavior in the classroom teaching, we get: (1) Teacher evaluation behavior in classroom is close to take 1/5 of the total time of the classroom teaching, and it appears most frequently in class exercises and take the longest time; (2) There are many forms of teacher evaluation behavior in classroom, and most of the behaviors are positive assessment; (3) Recognition evaluation is relatively conservative in a single form without losing fairness; (4) Classroom assessments of teachers' behaviors are primarily concerned about students' knowledge and skills mastery, and it is less involved in student feelings, attitudes and behaviors; (5) The correct teacher evaluation behavior in classroom will inspire students to create internal motivations; and (6) The correct teacher evaluation behavior in classroom can stimulate the potential of students.

• Journal of Applied Biological Chemistry
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• v.50 no.4
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• pp.187-195
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• 2007

The cord blood serves as a vehicle for the transportation of oxygen and nutrients to the fetus. In the past, the human cord blood has generally been discarded after birth. However, numerous studies have described the regenerative ability of the cord blood cells in various incurable diseases. The umbilical cord blood (UCB)-derived stem cells are obtained through non-invasive methods that are not harmful to both the mother and the fetus. Furthermore, the cord blood stem cells are more immature than the adult stem cells and expand readily in vitro. The mesenchymal stem cells (MSCs) have the capacity to differentiate in vitro into various mesodermal (bone, cartilage, tendon, muscle, and adipose), endodermal (hepatocyte), and ectodermal (neurons) tissues. This review describes the immunological properties of the human UCB-MSCs to assess their potential usefulness in the allogeneic transplantation for the regenerative medicine.

• Journal of Fisheries and Marine Sciences Education
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• v.26 no.1
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• pp.166-178
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• 2014

Purpose of this study was conducted to investigate the factors influencing smartphone addiction of high school students. The data were collected from 351 high school students in B city and analyzed with t-test, ANOVA and multiple regression by using SPSS 18.0 program. The smartphone addiction rate was 20.8%, which the high risk group rate was 8.5% and potential risk group rate was 12.3%. The significant factors of smartphone addiction were using time in weekend, accident in using smartphone, aggression, depression, attachment to peer and behavior control of learning attitude. And these factors explained 33.4% of the variance in smartphone addiction. In conclusion, the results from this study indicated a need to develop the intervention program to prevent smartphone addiction.

• Journal of Korea Foundry Society
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• v.38 no.2
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• pp.27-31
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• 2018

The lack of industrial manpower that Korean companies have been suffering in 21st century is largely responsible for the low-fertility phenomenon. This research suggests an alternative solution with a program for fostering foreign laborers with technical skills in casting industry. Industrial manpower growth is feasible through accepting migrants who have had official education on the fundamental industrial technologies provided by Korean government. These technically trained migrants who can keep economical self-perpetuating ability are can help to effectively address the problem of the declining working-age population and the decreasing potential growth rate in Korea.

• Journal of Digital Convergence
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• v.9 no.1
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• pp.51-59
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• 2011

The objective of this paper is to identify factors influencing intention to use ubiquitous banking service focusing on potential users using a regression model. Through this, providers of ubiquitous banking services can get an idea of future development, including marketing strategy through the results of this analysis. This paper proposes that perceived usefulness is the most important factor influencing the uptake of ubiquitous service. Also in addition, ANOVA test shows that higher education level of the user can lead to the higher intention to use an ubiquitous banking service. In this study, we set up a model by using the most basic factor among influential factors presented in previous studies as an independent variable. However, other research variables which affect acceptance of ubiquitous service should be considered by thinking more diversely.

• Bulletin of the Korean Chemical Society
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• v.31 no.1
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• pp.177-180
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• 2010

• Korean Journal of Crystallography
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• v.10 no.2
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• pp.130-135
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• 1999

The title compound consisting of a calix[4]arene molecule with four phenyl rings bridged by four methylene groups and arranged alternately in anti-orientation fashion, two 25,27-bis(1-pro-pyloxy) groups attached on the two lower rims of calix[4]arene, and crown-6 chain attached on the other set of lower rims of calix[4]arene offers a big cavity inside a molecule which might possess a potential for forming host-guest complexes. The molecular packing is accomplished by van der Waals forces.