• Title/Summary/Keyword: East Asian medicine

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Development of Yak-Sun for Excess Syndrome Obesity (1) Effects of Weight, Serum Glucose, Insulin and Lipid Profiles of Oriental Medicinal Herbs with Removal of Dampness through Diuresis (실증성(實證性) 비만을 위한 약선식 개발에 관한 연구 (1) 이습(利濕) 작용이 있는 한약재 혼합 추출물이 체중과 혈청 포도당, 인슐린 농도 및 지질 조성에 미치는 효과)

  • Park Sung-Hye
    • Journal of the East Asian Society of Dietary Life
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    • v.15 no.6
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    • pp.700-706
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    • 2005
  • We are concerned about how to apply the theories of oriental medicine appropriately, which direction should it be taken, and how it should be developed. And it is believed to be essential for the government to make efforts to set a standard and laws to validate the medicinal effects and process of the assessment so that the systematic development can be encouraged, and to prepare guidance for the food development for national health improvement Ihis study was peformed to provide basic data that predict the usefulness of oriental medicinal herbs to remove the dampness through diuresis for excess syndrome obesity with oriental diet therapy cuisine(Yak-Sun). Five oriental medicininal herbs, Coix lachryma-jobi L, Atractylodes lancea DC., Ligusticum wallichii F., Angelica sinensis D., Zingiber officinale R. were collected and made into mixing extracts(OMCE). And we examined the effects of OMCE on body weight serum glucose, insulin and lipid profile improvement in rats fed high fat diets. Sprague-Dawley rae(230-250 g) were randomly divided into five groups : basal diet(normal diet control group, NCG), only high fat diet(High fat control group, HCG), high fat diet and supplemented with 25mg/100g body weight 50mg/100g body weight 75mg/100g body weight by OMCE(HLG, HMG, HHG). These experimental diets were fed for 6 weeks. The OME fed groups decreased more significantly in weight serum glucose insulin and lipids than the high fat control group did. These results imply that the OMCE can be used as a safe and clinically applicable ingredients for diet called Yaksun of excess syndrome obesity in human.

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Analysis of Chemical Composition and Antioxidant Activity of Suaeda japonica (칠면초의 성분 분석 및 추출물의 항산화 효과)

  • Lee, Kyung-Seok;Kim, Ae-Jung;Lee, Ki-Young
    • Journal of the East Asian Society of Dietary Life
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    • v.22 no.4
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    • pp.521-526
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    • 2012
  • This study was conducted in order to analyze the ingredients and antioxidant activity of Suaeda japonica (turkey), which is abundantly present in Korea where mud flats are well formed due to the characteristics of halophytes. In the analysis of general composition, contents of carbohydrates, proteins, ash, and moisture were 10.7%, 8.3%, 7.6%, and 72.5% respectively. Among minerals, sodium was measured as 5.4%, which means that most ash was made of sodium. Heavy metal contents of lead, cadmium, arsenic, and mercury were 0.86 ppm, 0.04 ppm, 0.39 ppm, and 0.01 ppm, meaning Suaeda japonica satisfied standard food values. The 70% ethanol extract from Suaeda japonica was evaluated for its free radical scavenging activity and compared with a commercial antioxidant, BHA (butylated hydroxyanisole). As a result, the scavenging activities of hydroxyl radical, hydrogen peroxide, and xanthine oxidase of the extracts were equivalent to 30~50% of that of BHA.

Development of An Anti-Diabetic Functional Drink (I) - Screening of the Manufacturing of Mulberry Leaf Extract - (상엽 추출물을 이용한 항당뇨 음료의 개발 (I) - 상엽 추출물의 제제화 탐색 -)

  • 구성자;윤기주;김근풍
    • Journal of the East Asian Society of Dietary Life
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    • v.12 no.5
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    • pp.364-369
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    • 2002
  • Mulberry leaves are believed to be a potent inhibitor of intestinal $\alpha$-glycosidase and the digestion of sucrose in the small intestine. Mulberry leaves are also blown to help prevent the postprandial hyperglycemia. The objective of this study was to elucidate the functionality and anti-hyperglycemic effect of mulberry leaves, and to develop a functional drink using mulberry leaf, silk peptide and oriental medicine. Several mixtures of mulberry lear extract silk peptide and oriental medicine were made for the purpose of manufacture and formulation of products. These mixtures were tested to check the $\alpha$-glycosidase inhibition effect to find the best formula. The optimum conditions for a mulberry leaf hot water extract were that the size of leaf was under 3mm, the amount of leaf needed 50~100 g/L, extraction temperature 9$0^{\circ}C$ and extraction time 2 hr. The yield of extraction was 20~25%. The anti-hyperglycemic effect of mulberry leaves was at maximum when the concentrations of mulberry leaf extract and silk peptide were 1% and 0.1%, respectively.

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Anti-Obese Effects of Ginseng/Ginsenosides : A Literature Review from 1983 to 2012 (인삼과 진세노사이드의 항비만 효과에 대한 문헌 고찰)

  • Choi, Munji;An, Jinpyo;Kim, Ae Jung;Lee, Myoungsook
    • Journal of the East Asian Society of Dietary Life
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    • v.24 no.3
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    • pp.335-350
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    • 2014
  • Compared to the large numbers of studies on the diabetes, hyperlipidemia and cancer therpeutic effects of ginseng, the anti-obese effect and mechanisms of ginsengs have not been studied as much. To determine the effects of ginseng on obesity, 14 keywords (ginseng, ginsenoside, obesity, weight, fat, diet, overeat, appetite, lipid, 3T3-L1, adipocyte, food intake, adipogenesis and lipolysis) were combined in searching a database. Fifty-six articles published from 1983 to 2012 as well as 656 patents registered until Aug $17^{th}$, 2012, were screened for anti-obese effects of ginseng. In the classification of experimental methods, 16 papers on 3T3-L1 cells, 38 papers on animals and three papers on human were reviewed. In terms of obese mechanisms of action, the most commonly used biomarkers were in order of lipid profiles > weight change > blood glucose > adipocytokine. Most ginseng studies on obesity focused on AMPK, $PPAR{\gamma}$, GLUT-4, PI3K and SREBP-1. Korean white ginseng extracts and Re repressed the lipogenesis genes such as PPARc2, SREBP-1c, LPL, FAS and DGAT1. However, ginseng or ginsenosides, PD (Rb1) and PT (Re), showed different or contradictory results. Water and ethanol extraction of ginseng showed contradictory effects on the secretion of inflammatory cytokines, wheras IL-6 was repressed by ethanol extracts and TNF-${\alpha}$ repressed by Re in vitro. Based on the literature, further studies on anti-obese mechanisms of ginseng, such as the inflammation-related obesity or cross signals between the adipocytes and the environments, are needed, instead of more studies on its hypolipidemic and hypoglycemic effects.

Preparation and Characterization of Black Ginseng Tofu (흑삼농축액을 이용한 흑삼두부 제조 및 품질 특성)

  • Kim, Min-Jeong;Kim, Ae-Jung;Shin, Jeong-Hee
    • Journal of the East Asian Society of Dietary Life
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    • v.22 no.1
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    • pp.68-74
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    • 2012
  • This study was performed to process Tofu as an hypolipidemic food using black ginseng. Before processing we performed the ameliorating effect of black ginseng on the serum levels of triglyceride and total cholesterol in diabetic mice (db/db mice). As a result, the diabetic mice, whose diet was supplemented with black ginseng has a reduced level of serum lipid total cholesterol ($124.58{\pm}10.59mg/dL$) compared to non-supplemented diabetic mice, The supplemented mice exhibited a significant decrease (p<0.05) in serum lipid triglycerides ($80.32{\pm}35.40mg/dL$), which provided the efficacy of black ginseng in reducing hyperlipemia, thus indirectly proving the prevention and treatment of obesity. Then we processed Tofu as a hypolipidemic food using 0~8% black ginseng extract. We evaluated the quality characteristic after producing black ginseng Tofu. For color value, as the addition level of color increases, the value of L (lightness) decreased and a (redness), b (yellowness) increased. With increase in black ginseng concentrate additional level increases, the hardness, gumminess, and chewiness values increased (p<0.05), but the springiness and cohesiveness showed no significant differences. In case of sensory evaluation, Tofu with the addition of 2% black ginseng concentrate (BGT2) showed the highest preference overall. To sum up, black ginseng demonstrated pharmacological effects in treating diabetic complications like hyperlipidemia and reducing body deposit fat.

Effects of Ethanol-Extract of Lotus Root on the Renal Function and Blood Pressure of Fructose-Induced Hypertensive Rats (연근의 에탄올 추출물이 과당으로 유도된 고혈압 흰쥐의 혈압과 신장 기능에 미치는 효과)

  • Park Sung-Hye;Ham Tae-Sick;Han Jong-Hyun
    • Journal of the East Asian Society of Dietary Life
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    • v.15 no.2
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    • pp.165-170
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    • 2005
  • The present study was aimed to investigate whether ethanol-extract of Nelumbo nucifera has an ameliorative effect on the renal function in high fructose-diet induced hypertensive rats. The urine osmolality (Uosmel) was decreased in rats with high fructose-diet ($60\%$) during the whole experiment period without change of the urine volume (UV). The urinary excretion of sodium and chloride were decrease significantly in rats with fructose induced hypertensive rats, wheras urinary excretion of potassium was increased. The creatinine clearance (CCr) and solute-free water reabsorption were also decreased by treatment of fructose rich diet. Among these renal functional parameters, CCr was partially restored by the administration of ethanol-extract of Nelumbo nucifera. The Uosmol was also partially restored by the administration ethanol-extract of Nelumbo nucifera at the end of the experimental period. Taken together, ethanol-extract of Nelumbo nucifera has the ameliorative effect on glomerular filtration rate in rats with high fructose-diet induced hypertension.

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Analysis of the Job of Nurses Working on Oriental Medicine Wards (일부 한방병동간호사의 직무분석)

  • Kim, Myung Ja;Kim, Mi Hwan;Jeong, Hee Sug;Kim, Yun Seo
    • Journal of Korean Academy of Nursing Administration
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    • v.21 no.4
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    • pp.341-353
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    • 2015
  • Purpose: The purpose of this study was to identify nurse's role through job analysis of nursing duties for nurses working on East Asia traditional medicine wards. Methods: Major steps in the study included a literature review, description of job activities of nurses on oriental medicine wards, comparative description of the literature, expert tests of validity of derived duties and tasks, and investigation of importance, difficulty and frequency of duties on job list. Results: The job of nurses on oriental medicine wards was classified into 12 duties, 59 tasks, and 295 task elements. The 12 duties were nursing assessment, nursing diagnosis, nursing planning, nursing implementation, nursing evaluation, supplies management, management of human resources, management of environment, management of documents, formation of cooperative relationships, self-development, and nursing activity in oriental medicine. 'Formation of cooperative relationships' was the duty ranked highest for importance (4.34), 'self-development' was ranked highest for difficulty (3.47), and 'Formation of cooperative relationships' was ranked highest for frequency (4.21). Conclusion: Basic education for nurses on an oriental medicine unit is necessary for the performance of oriental nursing to be considered as a specialized field. This study contributes to human resource management in the oriental medical hospital.

Individual experience reports and statements on general rules in medical classics (의학 고전의 개별 경험 진술과 일반 원칙 서술)

  • Kiwang, Kim
    • Journal of Korean Medical classics
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    • v.30 no.2
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    • pp.1-10
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    • 2017
  • Objectives : In studying East Asia's medical classics, what must first be done before evaluating the validities of clinical grounds is the discernment of the techniques that are based on universal principles from the statements that arise from individual experience. The purpose of this paper is to discover a method of discerning the statements of individual experiences and the descriptions of universal principles. Ingredients and Methods : The paper investigates how each individual clinical experience was introduced in ancient medical classics such as Huangdineijing, Nanjing, Shanghanlun, Jinkuiyaolue, and Maijing, in the books that belong to Yian such as Canggongliechuan, Linzhengzhinanyian, Gujinyianan, and Xumingyileian, and in Korean ancient medical texts such as Eonhae-gugeubbang and Gugeubganibang-eonhae. Results : Books of precriptions and scriptures of medicine were found to include individual experiences. Furthermore, this paper's effort has revealed that the evaluation of the quality of a testimony in an ancient book must be preceded by discerning whether the said testimony is a mere personal testimony or a testimony based on the universal law of causality. Conclusions : Before conducting a clinical research of a precription contained in an East Asian medical classic, the text should first be evaluated to determine whether the prescription in question derives from clinical tests or not.

Employee's Negative Psychological Factors Based on Excessive Workloads and Its Solutions Using Consultation with the Manager

  • PARK, Hye-Ryoung;KIM, Seong-Gon
    • East Asian Journal of Business Economics (EAJBE)
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    • v.10 no.1
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    • pp.59-69
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    • 2022
  • Purpose - Burnouts cause the workers to quit their jobs because with the heavy workloads that the employees get subjected to, they feel that they have little control over what they have to accomplish in the workplace. The purpose of this research is to provide adequate solutions using brief consultation process, reducing negative psychological factors. Research design, Data, and methodology - The current research conducted the 'Qualitative Content Analysis' (QCA), which is one of the most employed analytical tools; it has been used widely all over the globe in various research applications in library science and information. Primarily, this analysis is often used as a method in the quantitative tool until the recent decade. Result - Based on ultimate systematic literature analysis, excessive workloads can get addressed by finding proper solutions to the issues of depression, anxiety, irritability, and discouragement. The solutions are (1) Combating Excessive Workloads using Effective Employee Selection, (2) Employee Effective training, and (3) Job redesigning. Conclusion - Selecting or recruiting employees that have skills for the given job also makes it possible for the organization to run its employees effectively and with minimal cases of workload as an organization understands the capabilities and capacities of workload an employee can complete.

Web-Based Database and Viewer of East Asian Copy Number Variations

  • Kim, Ji-Hong;Hu, Hae-Jin;Chung, Yeun-Jun
    • Genomics & Informatics
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    • v.10 no.1
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    • pp.65-67
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    • 2012
  • We have discovered copy number variations (CNVs) in 3,578 Korean individuals with the Affymetrix Genome-Wide SNP array 5.0, and 4,003 copy number variation regions (CNVRs) were defined in a previous study. To explore the details of the variants easily in related studies, we built a database, cataloging the CNVs and related information. This system helps researchers browsing these variants with gene and structure variant annotations. Users can easily find specific regions with search options and verify them from system-integrated genome browsers with annotations.