• 한국통신학회논문지
• /
• 제34권5C호
• /
• pp.521-526
• /
• 2009

In this paper, a complex-valued recursive least squares escalator filter algorithm with reduced computational complexity for complex-valued signal processing applications is presented. The local tap weight of RLS-ESC algorithm is updated by incrementing its old value by an amount equal to the local estimation error times the local gain scalar, and for the gain scalar, the local input autocorrelation is calculated at the previous time. By deriving a new gain scalar that can be calculated by using the current local input autocorrelation, reduced computational complexity is accomplished. Compared with the computational complexity of the complex-valued version of RLS-ESC algorithm, the computational complexity of the proposed method can be reduced by 50% without performance degradation. The reduced computational complexity of the proposed algorithm is even less than that of the LMS-ESC. Simulation results for complex channel equalization in 64QAM modulation schemes demonstrate that the proposed algorithm has superior convergence and constellation performance.

• 한국산학기술학회논문지
• /
• 제7권6호
• /
• pp.998-1003
• /
• 2006

본 연구에서는 디젤기관의 친환경 대체연료인 GTL 연료 사용으로 인한 기관성능 및 배출가스의 특성을 알아보기 위하여 12,000cc급 대형디젤기관을 기관성능 모드에서 GTL 및 ULSD 연료를 사용하여 실험 분석하였으며 단일 모드를 사용하여 기관 속도 및 부하에 따른 배출가스 특성을 파악하였고, 최종적으로 2006년 현재 국내 규제시험 모드이고 유로IV 규제 모드인 ESC 모드를 사용하여 GTL연료의 성능 및 배출가스의 배출 특성을 분석하여 현재 운행 중인 대형디젤기관으로의 적용 가능성을 검토하였다.

• 천문학회보
• /
• 제43권2호
• /
• pp.55.1-55.1
• /
• 2018

Theoretical models of reionization require that approximately 10% of the Lyman Continumm (LyC) photons escape from their host dark matter haloes and re-ionize neutral hydrogen in the Universe. However, observations of Lyman break galaxies (LBGs) at z~3 report much lower escape fractions of $f_{esc}{\sim}1%$. In an attempt to understand the discrepancy, we perform radiation-hydrodynamics simulations of isolated disk galaxies using RAMSES-RT with high resolution (maximum ~ 9 pc). We find that $f_{esc}$ is ~6% on average for the reference run ($Z=0.1Z{\odot}$), whereas the fraction decreases to ~1% in the case of metal-rich disk ($Z=1Z{\odot}$). This happens because dense metal-poor gas clumps are disrupted early due to strong Lya pressure and supernova explosions, while star particles are trapped for a longer period of time in the metal-rich environments. We also find that $f_{esc}$ is still significant (~4%) even when the amount of metal-poor gas is increased by a factor of 5. Our preliminary results suggest that the low escape fractions in LBGs may be better explained by (locally) metal-enriched gas near young stars than high gas fractions in galaxies.

• Clinical and Experimental Reproductive Medicine
• /
• 제31권4호
• /
• pp.261-271
• /
• 2004

Objective: This study was performed to evaluate the possibility of prolonged culture of human embryonic stem cells (hESC; SNUhES2) on human amniotic fluid cells (hAFC), which had been storaged after karyotyping. Method: The hAFC was prepared for feeder layer in the presence of Chang's medium and STO medium (90% DMEM, 10% FBS) at $37^{circ}C$ in a 5% $CO_2$ in air atmosphere. Prior to use as a feeder layer, hAFC was mitotically inactivated by mitomycin C. The hESCs on hAFC were passaged mechanically every seven days with ES culture medium (80% DMEM/F12, 20% SR, bFGF). Results: The hAFC feeder layer support the growth of undifferentiated state of SNUhES2 for at least 59 passages thus far. SNUhES2 colonies on hAFC feeder appeared slightly angular and flatter shape as compared with circular and thicker colonies observed with STO feeder layer and showed higher level with complete undifferentiation in seven days. Like hESC cultured on STO feeders, SNUhES2 grown on hAFC expressed normal karyotype, positive for alkaline phosphatase activity, high telomerase activity, Oct-4, SSEA-3, SSEA-4, Tra-1-60 and Tra-1-81 and formed embryoid bodies (EBs). Conclusion: The hAFC supports undifferentiated growth of hESC. Therefore, these results may help to provide a clinically practicable method for expansion of hESC for cell therapies.

• 한국농공학회논문집
• /
• 제60권1호
• /
• pp.21-30
• /
• 2018

In this study, we developed the Soil Moisture Data Assimilation (SMDA) scheme to extract Effective Soil Characteristics-ESC (Sand, Silt, Clay %) from MODerate resolution Imaging Spectroradiometer (MODIS) products. The SMDA scheme was applied to the MODIS-based Soil Moisture (SM) data during the summer (July to September) period. Then the ESC and soil erosion factors (K) were predicted, respectively. Several numerical experiments were conducted to test the performance of SMDA at the study sites under the synthetic and field validation conditions. In the synthetic experiment, the estimated soil moistures values(R: >0.990 and RMSE: <0.005) were identified well with the synthetic observations. The field validation results at the Bangdongri and Chungmicheon sites were also comparable to the TDR-based measurements with the statistics (R: 0.772/0.000 and RMSE: 0.065/0.000). The estimated ESC values were also matched well with the measurements for the synthetic and field validation conditions. Then we tested the SMDA scheme to extract the ESC from the MODIS-based soil moisture products. Although uncertainties exist in the results, the estimated soil moisture and ESC based on the SMDA were comparable to the measurements. Overall, the K factors were similarly distributed based on the derived ESC. Also, the K factors in the mountainous regions were higher than those of the relatively flat areas. Thus, the newly developed SMDA scheme can be useful to estimate spatially and temporally-distributed soil erosion and establish soil erosion management plans.

• 대한전기학회:학술대회논문집
• /
• 대한전기학회 1999년도 하계학술대회 논문집 F
• /
• pp.2505-2507
• /
• 1999

This paper presents novel self excited DC-DC converters such as Buck-boost type, Buck type and also non-inverting Buck-boost type. The proposed converters has the following advantages: simple topology, small number of circuit components, easy control methode. Therefore, these converters are suitable for the portable appliances with battery source. Theoretical analysis and experimental results for SOW class Buck-boost type self oscillation DC-DC converter have been obtained, which demonstrate the high efficiency and good performance.

• 대한기계학회논문집A
• /
• 제40권1호
• /
• pp.103-111
• /
• 2016

본 논문에서는 차량의 횡방향 안정성을 향상시키기 위해 자세 제어 장치(ESC)와 능동 전륜 조향(AFS)을 이용하는 통합 새시 제어의 적응 가변 가중치 조절 방법을 제안한다. 제어기 설계 방법론을 적용하여 차량을 안정화시키는데 필요한 제어 요 모멘트를 구한 후 이를 가중 역행렬 기반 제어 할당 방법(WPCA)을 이용하여 ESC 의 제동력과 AFS 의 추가 조향각으로 분배한다. 저마찰 노면에서는 차량의 속도가 높다면 횡슬립각이 증가하여 횡방향 안정성이 저하되므로 이를 방지하기 위해 WPCA 의 가변가중치를 상황에 따라 조절하는 방법을 제안한다. 차량 시뮬레이션 패키지인 CarSim 에서 시뮬레이션을 수행하여 제안된 방법이 통합 섀시 제어기의 횡방향 안정성을 향상시킨다는 사실을 검증한다.

• Asian Pacific Journal of Cancer Prevention
• /
• 제13권9호
• /
• pp.4295-4300
• /
• 2012

Objective: To investigate the therapeutic potential of human embryonic stem cells (hESCs) as a vaccine to induce an immune response and provide antitumor protection in a rat model. Methods: Cross-reactivity of antigens between hESCs and tumour cells was screened by immunohistochemistry. Fischer 344 rats were divided into 7 groups, with 6 rats in each, immunized with: Group 1, hESC; Group 2, pre-inactivated mitotic NuTu-19; Group 3 PBS; Group 4, hESC; Group 5, pre-inactivated mitotic NuTu-19; Group 6, PBS; Group 7, hESC only. At 1 (Groups 1-3) or 4 weeks (Groups 4-6) after the last vaccination, each rat was challenged intraperitoneally with NuTu-19. Tumor growth and animal survival were closely monitored. Rats immunized with H9 and NuTu-19 were tested by Western blot analysis of rat orbital venous blood for cytokines produced by Th1 and Th2 cells. Results: hESCs presented tumour antigens, markers, and genes related to tumour growth, metastasis, and signal pathway interactions. The vaccine administered to rats in Group 1 led to significant antitumor responses and enhanced tumor rejection in rats with intraperitoneal inoculation of NuTu-19 cells compared to control groups. In contrast, rats in Group 4 did not display any elevation of antitumour responses. Western blot analysis found cross-reactivity among antibodies generated between H9 and NuTu-19. However, the cytokines did not show significant differences, and no side effects were detected. Conclusion: hESC-based vaccination is a promising modality for immunotherapy of ovarian cancer.

• Structural Engineering and Mechanics
• /
• 제56권4호
• /
• pp.507-534
• /
• 2015

The present work investigates the behavior of the embankment models resting on soft soil reinforced with ordinary and stone columns encased with geogrid. Model tests were performed with different spacing distances between stone columns and two lengths to diameter ratios (L/d) of the stone columns, in addition to different embankment heights. A total number of 42 model tests were carried out on a soil with undrianed shear strength $${\sim_\sim}10kPa$$. The models consist of stone columns embankment at s/d equal to 2.5, 3 and 4 with L/d ratio equal 5 and 8. Three embankment heights; 200 mm, 250 mm and 300 mm were tested for both tests of ordinary (OSC) and geogrid encased stone columns (ESC). Three earth pressure cells were used to measure directly the vertical effective stress on column at the top of the middle stone column under the center line of embankment and on the edge stone column for all models while the third cell was placed at the base of embankment between two columns to measure the vertical effective stress in soft soil directly. The performance of stone columns embankments relies upon the ability of the granular embankment material to arch over the 'gaps' between the stone columns spacing. The results showed that the ratio of the embankment height to the clear spacing between columns (h/s-d) is a key parameter. It is found that (h/s-d)<1.2 and 1.4 for OSC and ESC, respectively; (h is the embankment height, s is the spacing between columns and d is the diameter of stone columns), no effect of arching is pronounced, the settlement at the surface of the embankment is very large, and the stress acting on the subsoil is virtually unmodified from the nominal overburden stress. When $(h/s-d){\geq}2.2$ for OSC and ESC respectively, full arching will occur and minimum stress on subsoil between stone columns will act, so the range of critical embankment height will be 1.2 (h/sd) to 2.2 (h/s-d) for both OSC and ESC models.

• Asian-Australasian Journal of Animal Sciences
• /
• 제31권3호
• /
• pp.335-343
• /
• 2018

Objective: Remarkable difference in cellular activity was found between early and late subpassaged embryonic stem cell (ESCs) lines, which can be created by subtle changes in cell manipulation protocol. This study subsequently examined whether post-thaw subculture of early subpassaged ESC lines could further affect the activity of the ESCs. Methods: Fresh (as a control treatment) or cryopreserved F1 hybrid (B6CBAF1) early ESC lines (C57BL/6xCBA) of the 4 (P4) or the 19 passage (P19) were subcultured once, twice or six times under the same condition. The post-thaw survival of the ESCs was monitored after the post-treatment subculture and the ability of cell proliferation, reactive oxygen species (ROS) generation, apoptosis and mitochondrial ATP synthesis was subsequently examined. Results: Regardless of the subculture number, P19 ESCs showed better (p<0.05) doubling time and less ATP production than P4 ESCs and such difference was not influenced by fresh or cryopreservation. The difference between P4 and P19 ESC lines became decreased as the post-treatment subculture was increased and the six times subculture eliminated such difference. Similarly, transient but prominent difference in ROS production and apoptotic cell number was detected between P4 and P19 ESCs only at the 1st subculture after treatment, but no statistical differences between two ESC lines was detected in other observations. Conclusion: The results of this study suggest that post-thaw subculture of ESCs under the same environment is recommended for standardizing their cellular activity. The activity of cell proliferation ability and ATP synthesis can be used as parameters for quality control of ESCs.