• Title/Summary/Keyword: ERADICATION

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Pseudomonas aeruginosa Biofilm, a Programmed Bacterial Life for Fitness

  • Lee, Keehoon;Yoon, Sang Sun
    • Journal of Microbiology and Biotechnology
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    • v.27 no.6
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    • pp.1053-1064
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    • 2017
  • A biofilm is a community of microbes that typically inhabit on surfaces and are encased in an extracellular matrix. Biofilms display very dissimilar characteristics to their planktonic counterparts. Biofilms are ubiquitous in the environment and influence our lives tremendously in both positive and negative ways. Pseudomonas aeruginosa is a bacterium known to produce robust biofilms. P. aeruginosa biofilms cause severe problems in immunocompromised patients, including those with cystic fibrosis or wound infection. Moreover, the unique biofilm properties further complicate the eradication of the biofilm infection, leading to the development of chronic infections. In this review, we discuss the history of biofilm research and general characteristics of bacterial biofilms. Then, distinct features pertaining to each stage of P. aeruginosa biofilm development are highlighted. Furthermore, infections caused by biofilms on their own or in association with other bacterial species (i.e., multispecies biofilms) are discussed in detail.

TREATMENT OF INFECTED MANDIBULAR FRACTURES (감염된 하악골 골절의 치험)

  • Kim, Hyoun-Chull
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.12 no.2
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    • pp.41-47
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    • 1990
  • Treatment of infected mandibular fractures is confronted with various difficult problem, e.g. eradication of infection and osseous union even in the presence of devastating infection. To solve this problem various methods were proved including exteranal fixation, IMF and plating with some success. Author treated 3 cases of infected mandibular fractures with champy's miniplate. 1. Satisfactory union was obtained in 3 cases. 2. In One case, pus drainage continued even after internal fixation with miniplate, but it was easily controlled using proper antibiotic therapy & drainage. 3. In Case 3, autogenous bone graft was implanted into the infected fracture site to fill defect.

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Expression of Cancer-Testis Antigens in Stem Cells: Is it a Potential Drawback or an Advantage in Cancer Immunotherapy

  • Ghafouri-Fard, Soudeh
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.7
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    • pp.3079-3081
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    • 2015
  • Cancer-testis antigens (CTAs) are a group of tumor associated antigens with a restricted expression pattern in normal gametogenic tissues but expression in a broad range of malignancies. Their expression pattern has made them potential targets for immunotherapy. However, expression of some of these antigens has been demonstrated in normal stem cells as well as cancer stem cells (CSCs). As CSCs have been shown to be sources of metastasis and tumor recurrence, novel therapies are being focused on their eradication. On the other hand, CTA expression in normal stem cells raises the possibility that CTA based immunotherapies cause side effects in normal tissues.

Investigation and Research on Japanese Terms used in the Korean Fishing Boats (어선에서 사용되는 일본식 용어에 관한 실태 조사(I) -갑판부 사용 용어 중심으로-)

  • KIM, Young-Un;KIM, Yong-Bok
    • Journal of Fisheries and Marine Sciences Education
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    • v.14 no.1
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    • pp.79-94
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    • 2002
  • In the Korean fishing boats, the abuse of Japanese term is intense. It becomes a reason of preventing the free communications between the crews who have been working for long time in the ship and crews who start new life in the ship as beginner. Also the former cannot feel and understand easily the contents of the textbook and manual which are explained with Korean or English terminology. It is reasonable that Japanese terms are no longer use in the vessel if possible. We searched and classified 170 or more Japanese terms which are used popularly in the fishing boats. So, we expect this paper is a basic research for the eradication of the Japanese terms in the Korean fishing boats.

Investigation for Purification of Japanese Style Terminology Used in the Korean Fishing Vessels (어선에서의 일본식 용어 순화에 관한 연구)

  • Kim, Young-Un
    • Journal of Fisheries and Marine Sciences Education
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    • v.25 no.4
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    • pp.836-847
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    • 2013
  • In contemporary society, shipping and fishery industry tend to use Japanese language or Japanese style terminology extravagantly. It becomes a reason of preventing the communications between crews who have been working for many years and the beginners in the ships. Also the crews cannot easily understand the contents of the manuals that is explained in only Korean language. For this reason, the foreign employee have to study Japanese style terminology before begin start their work. I strongly believe that this is one of the major national contempt. It is reasonable to expel Japanese style terminology from the vessel if possible to enable free communications to each other. I inspected and examined about purification of 125 Japanese style terminology that is already examined in the fishing vessels 11 years ago. So, I expect this paper is a research for the eradication of the Japanese style terminology in the Korean fishing vessels.

Phosphagen Kinases of Parasites: Unexplored Chemotherapeutic Targets

  • Jarilla, Blanca R.;Agatsuma, Takeshi
    • Parasites, Hosts and Diseases
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    • v.48 no.4
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    • pp.281-284
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    • 2010
  • Due to the possible emergence of resistance and safety concerns on certain treatments, development of new drugs against parasites is essential for the effective control and subsequent eradication of parasitic infections. Several drug targets have been identified which are either genes or proteins essential for the parasite survival and distinct from the hosts. These include the phosphagen kinases (PKs) which are enzymes that playa key role in maintenance of homeostasis in cells exhibiting high or variable rates of energy turnover by catalizing the reversible transfer of a phosphate between ATP and naturally occurring guanidine compounds. PKs have been identified in a number of important human and animal parasites and were also shown to be significant in survival and adaptation to stress conditions. The potential of parasite PKs as novel chemotherapeutic targets remains to be explored.

Surgical Experience of Aortic Root Abscess with Complete AV Block and Pseudoaneurysm (완전 방실 차단과 가성 동맥류를 동반한 만성 대동맥 근부농양 수술적 치험)

  • 한국남;오세진;구본권;김경환
    • Journal of Chest Surgery
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    • v.37 no.10
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    • pp.868-871
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    • 2004
  • A 42 year old male was operated with aortic root abscess and pseudoaneurysm. Aortic valve vegetations which measured $8\times5$ cm and root abscess were removed and debrided. We reconstructed root and noncoronary sinus with autopericardium. Antibiotics were administered for 4 weeks. In general, Aortic root abscess recurs frequently and mortality is high. It is usually requires early surgical eradication with antibiotics medication.

Antilisterial Bacteriocin from Lactobacillus rhamnosus CJNU 0519 Presenting a Narrow Antimicrobial Spectrum

  • Jeong, Ye-Jin;Moon, Gi-Seong
    • Food Science of Animal Resources
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    • v.35 no.1
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    • pp.137-142
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    • 2015
  • A lactic acid bacterium presenting antimicrobial activity against a Lactobacillus acidophilus strain used for eradication of acid inhibition was isolated from a natural cheese. The 16S rRNA gene sequence of the isolate best matched with a strain of L. rhamnosus and was designated L. rhamnosus CJNU 0519. The antimicrobial activity of the partially purified bacteriocin of CJNU 0519 was abolished when treated with a protease, indicating the protein nature of the bacteriocin. The partially purified bacteriocin (rhamnocin 519) displayed a narrow antimicrobial activity against L. acidophilus, Listeria monocytogenes, and Staphylococcus aureus among several tested bacterial and yeast strains. Rhamnocin 519 in particular showed strong bactericidal action against L. monocytogenes.

국내 기생충 질환의 현황 및 전망

  • Chae, Jong-Il
    • Journal of Korea Association of Health Promotion
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    • v.1 no.1
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    • pp.26-32
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    • 2003
  • The current status and future prospects of parasitic infections in Korea is briefly reviewed. Soil-transmitted helminth infections including ascariasis, trichuriasis, and hookworm infections decreased remarkably. owing to the national control activities excuted by the Korea Association of Health Promotion(formerly Korea Association of parasite Eradication) using mass heath education. Important recent trends include reemergence of vivax malaria since 1993, persistence of food-borne trematode infections including clonorchiasis and intestinal trematode infections, increased detection of zoonotic parasitosis, close-up of infection with opportunistic parasites including cryptosporidiosis, toxoplasmosis, and pneumosytosis, increase of imported tropical infectious disease, appearance of new parasitic disease such as gymnophalloidiasis, and increase of accidental infections with free-living amoebae. These trends represent greatly changed overall patterns of parasitic infections in Korea.

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Strengthening of Veterinary Services for Safety and Quality Control of the Livestock Products as Food in the Market Internationalization Era (국제관방화 시대에 있어서 축산식품의 안전성 및 품질에 대한 수의학적 관리강화 방안)

  • 박근식;박종명;조준형
    • Korean Journal of Poultry Science
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    • v.18 no.2
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    • pp.121-135
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    • 1991
  • Facing the international open-trade of agricultural and livestock products, a basic strategy is urgently necessary to improve the domestic livestock industry to an international level. Price and quality competitions are the most important target in international trade. Improvement in productivity of livestock is the most important factor in price competition. In recent trade of livestock products, quality competition becomes more important than price competition in livestock products, and will be severer in the future. Basic strategies for higher productivity and safety of livestock products are listed as follows : 1. Protection from exotic diseases 2. Eradication of indigenous diseases 3. Development of new methods and techniques for control of animal diseases 4. Application of hygiene and management techniques 5. Safety evaluation of feedstuffs and animal drugs, and 6. Development of technique and regulations for prevention and monitoring of residue of harmful chemicals.

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