• Title/Summary/Keyword: EPI

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Review on the reliability of low frequency responses of locally operating sensors (국내 지진센서의 저주파 응답의 신뢰성에 관한 고찰)

  • 박동희;연관희;장천중
    • Proceedings of the Earthquake Engineering Society of Korea Conference
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    • 2002.09a
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    • pp.35-42
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    • 2002
  • Frequency responses for most of the local seismic sensors in Korea have been roughly checked by mutual comparison of Fourier spectra of seismic records from accelerometer and seismometer, both of which are installed at the same location. Especially, because the frequency content of the seismic energy is usually above 1 Hz for local earthquakes, the reliability of low frequency response could have not been evaluated. Fortunately a recent large earthquake, Ms=7.2 on 02/06/29 containing dominant low frequency energy makes it possible to check the low frequency response of the seismic sensors, especially EpiSensor and JC-V100. Considering two types of sensor pairs, (STS-2 and EpiSensor, JC-V100 and EpiSensor), the low frequency response of EpiSensor is confirmed first by comparison with STS-2 which has proved low frequency response. Second, reliable low frequency limit of instrumentally corrected seismic data from JC-V100 data is estimated to be about 0.03 Hz by comparison with EpiSensor data.

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Synthesis of Cyclitol Derivatives (IV) Electrolytic Reduction of DL-epi-inosose-2 (Cyclitol 유도체 합성에 관한 연구 (제4보) DL-epi-inosose-2의 전해환원)

  • Sohn, Joo-Hwan;Nam, Chong-Woo;Park, Heung-Cho
    • Journal of the Korean Chemical Society
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    • v.16 no.2
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    • pp.93-99
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    • 1972
  • To obtain the various kinds of inositol stereomers, we have selected the process of electrolytic reduction of DL-epi-inosose-2 using Ni, Ta, Cu, Mo, Pb, Sn, W, Cd and Hg etc., as cathode. We think that this process gives greater variety than chemical processes. DL-epi-inosose-2 was synthesized by chemical oxidation of myo-inositol, dissolved in aqueous solution of potassium hydroxide, and used as electrolytic solution. To prevent anodic oxidation of cathode products the H-type diaphragm cell was used. As the results of paper chromatography of cathodic products, we obtained the $R_f$ values of myo-inositol and epi-inositol were in good agreement with literature values.

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Suspected Case of Exocrine Pancreatic Insufficiency in a Bengal Tiger (Panthera tigris tigris)

  • Rhim, Haerin;Han, Jae-Ik
    • Journal of Veterinary Clinics
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    • v.35 no.5
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    • pp.240-242
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    • 2018
  • A 1-year-old, female Bengal tiger (Panthera tigris tigris) presented signs of weight loss and dark browncolored diarrhea. On fecal examination, numerous intact and broken red blood cells were found, but both parasites and inflammatory signs were absent. No significant findings were seen in serum biochemistry profiles, including electrolytes, with negative feline pancreatic lipase immunoreactivity (fPLI). Diagnostic kits using feces or peripheral blood were negative for feline parvovirus, feline coronavirus, feline immunodeficiency virus, and feline leukemia virus. Based on the result of feline trypsin-like immunoreactivity (fTLI) concentration ($4.6{\mu}g/L$), the tiger was provisionally diagnosed to have exocrine pancreatic insufficiency (EPI). After this diagnosis, pancreatic enzymes were prescribed. The feces of the tiger returned to normal form and her weight was increasing. EPI is uncommon and not described extensively in Felidae, including domestic cats. Feline EPI is associated with a variety of non-specific signs and it should be considered in the differential diagnosis of cases presenting with weight loss, diarrhea, and other gastrointestinal signs. In this case, the patient was strongly suspected to have EPI based on the very low fTLI concentration, though the concentration of fTLI in tigers has not yet been determined. This is the first report to present a suspected EPI case in Bengal tigers.

Multi-Viewpoint Stereo Image Synthesis Using Multi-Resolution EPI Method (다해상도 EPI 방식에 의한 다시점 입체 영상 합성)

  • 장흥엽;이제호;권용무;김상국;박상희
    • Journal of Broadcast Engineering
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    • v.2 no.1
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    • pp.16-23
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    • 1997
  • Among the main technologies to implement 3D TV succeeding HDTV, multi-viewpoint image display technique is rising as an important issue, which can display the viewpoint-dependent images corresponding to viewer's position. This paper presents a novel method that solves too much computational overload that is main drawback of previous methods. Using down sampling technique, multiresolution EPIs are made from multi-viewpoint image set and trace lines are detected in the lowest resolution EPI. The parameters of detected trace lines are transferred to higher resolution EPIs and revised by utilizing the information of the previous resolution EPI. This procedure is iterated until orignal resolution EPI. Using the proposed method, we have achieved the reduction of computational time and the robustness to noise in comparison to previous method.

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Study on the Electrical Characteristics of the Multi-RESURF SOI LDMOSFET as a Function of Epi-layer Concentration (에피층 농도 변화에 따른 Multi-RESURF SOI LDMOSFET의 전기적 특성 분석)

  • Kim, Hyoung-Woo;Seo, Kil-Soo;Bahng, Wook;Kim, Ki-Hyun;Kim, Nam-Kyun
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.19 no.9
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    • pp.813-817
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    • 2006
  • In this paper, we analyzed the breakdown voltage and on-resistance of the multi-RESURF SOI LDMOSFET as a function of epi-layer concentration. P-/n-epi layer thickness and doping concentration of the proposed structure are varied from $2{\sim}5{\mu}m\;and\;1\{times}10^{15}/cm^{3}^{\sim}9\{times}10^{15}/cm^{3}$ to find optimum breakdown voltage and on-resistance of the proposed structure. The maximum breakdown voltage of the proposed structure is $224\;V\;at\;R_{on}=0.2{\Omega}-mon^{2}\;with\;P_{epi}=3\{times}10^{15}/cm^{3},\;N_{epi}=7\{times}10^{15}/cm^{3}\;and\;L_{epi}=10{\mu}m$. Characteristics of the device are verified by two-dimensional process simulator ATHENA and device simulator ATLAS.

${T_2}weighted$- Half courier Echo Planar Imaging

  • 김치영;김휴정;안창범
    • Investigative Magnetic Resonance Imaging
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    • v.5 no.1
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    • pp.57-65
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    • 2001
  • Purpose : $T_2$-weighted half courier Echo Planar Imaging (T2HEPI) method is proposed to reduce measurement time of existing EPI by a factor of 2. In addition, high $T_2$ contrast is obtained for clinical applications. High resolution single-shot EPI images with $T_2$ contrast are obtained with $128{\times}128$ matrix size by the proposed method. Materials and methods : In order to reduce measurement time in EPI, half courier space is measured, and rest of half courier data is obtained by conjugate symmetric filling. Thus high resolution single shot EPI image with $128{\times}128$ matrix size is obtained with 64 echoes. By the arrangement of phase encoding gradients, high $T_2$ weighted images are obtained. The acquired data in k-space are shifted if there exists residual gradient field due to eddy current along phase encoding gradient, which results in a serious problem in the reconstructed image. The residual field is estimated by the correlation coefficient between the echo signal for dc and the corresponding reference data acquired during the pre-scan. Once the residual gradient field is properly estimated, it can be removed by the adjustment of initial phase encoding gradient field between $70^{\circ}$ and $180^{\circ}$ rf pulses. Results : The suggested T2EPl is implemented in a 1.0 Tela whole body MRI system. Experiments are done with the effective echo times of 72ms and 96ms with single shot acquisitions. High resolution($128{\times}128$) volunteer head images with high $T_2$ contrast are obtained in a single scan by the proposed method. Conclusion : Using the half courier technique, higher resolution EPI images are obtained with matrix size of $128{\times}128$ in a single scan. Furthermore $T_2$ contrast is controlled by the effective echo time. Since the suggested method can be implemented by software alone (pulse sequence and corresponding tuning and reconstruction algorithms) without addition of special hardware, it can be widely used in existing MRI systems.

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Evaluation of Image Quality using SE-EPI and SSH-TSE Techniques in MRDWI (자기공명확산강조영상에서 SE-EPI 와 SSH-TSE 기법을 이용한 영상의 질 평가)

  • Goo, Eun-Hoe
    • Journal of the Korean Society of Radiology
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    • v.15 no.7
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    • pp.991-998
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    • 2021
  • The purpose of this study is to investigate the image quality of the SE-EPI and SSH-TSE technique for MR DWI. Datum were analyzed for 35 PACS transmission datum(Normal part: 12 males, 13 females, Cerebral Infarction: 10(5males and 5females), and average age 68±7.32), randomly selected patients who underwent MRDWI tests. The equipment used was Ingenia CX 3.0T, SSH_TSE and SE-EPI pulse sequence and 32 Ch. head coil were used for data acquisition. Image evaluation was performed on the paired t-test and Wilcoxon tests, and was considered significant when the p value was 0.05 or less. As a result of quantitative analysis of SNR for DWI images, the mean and standard deviation values of 4 parts (WM, GM, BG, Cerebellum) in ADC (s/mm2), Diffusion b=0, 1000 images were higher in SE-EPI techniques(ADC: 120.50 ± 40, b=0: 54.50 ± 35.91, b=1000: 91.61 ± 36.63) than in SSH-TSE techniques(ADC: 99.69 ± 31.10, b=0: 43.52 ± 25.00 , b=1000: 60.74 ± 24.85)(p<0.05). The CNR values for GM-WM, BG-WM sites were also higher in SE-EPI technique (ADC: 116.08 ± 43.30, b=0:27.23 ± 09.10, b=1000: 78.50 ± 16.56) than in SSH-TSE(ADC: 101.08 ± 36.81, b=0: 23.96 ± 07.79 , b=1000: 74.30 ± 14.22). As a visual evaluation of observers, ghost artifact, magnetic susceptibility artifacts and overall image quality for SE-TSE and SSH-TSE all yielded high results from SSH-TSE techniques(ADC:3.6 ± 0.1, 2.8 ± 0.2, b=0: 4.3 ± 0.3, 3.4 ± 0.1 b=1000: 4.3 ± 0.2, 3.5 ± 0.2, p=0.000). In conclusion, the SE-EPI technique obtained an superiority in SNR and CNR measurements using SSH-TSE, SE-EPI. In the qualitative analysis, the SSH-TSE pulse sequence was obtained a high result according to the pulse sequence characteristics.

Regulation of Bcl-2 Family and Cyclooxygenases by Furanoterpenoids Isolated from a Marine Sponge Swcotragus nt. in Human Lung Cancer A549 Cells. (인체폐암세포의 Bcl-2 family 및 cyclooxygenases의 발현에 미치는 해면동물 Sarcotragus sp. 유래 furanoterpenoids의 영향)

  • 최영현;최혜정;김남득;정지형
    • Journal of Life Science
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    • v.14 no.3
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    • pp.445-452
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    • 2004
  • We investigated the cytotoxic effects of seven furanoterpenoids 〔sarcotin A, epi-sarcotin A, ircinin-1, epi-sarcotrine B, sarcotin I, (8E, l3Z, 20Z)-strobilinin/(7E,l3Z, 20Z)-felixinin and (7E,12E,18R,20Z)-variabilin〕 isolated from the sponge Sarcotragus sp. (the order Dictyoceratida) on the growth of A549 human lung carcinoma cells. MTT data revealed that sarcotin A and (7E,12E,18R,20Z)-variabilin exhibited higher potencies on the anti-proliferative activities than the other compounds in A549 cells. The growth inhibition by treatment with compounds (especially epi-sarcotin A, ircinin-1 and epi-sarcotrine B) were associated with the induction of apoptotic cell death through the concentration-dependent increase of Bax/Bcl-2 ratio in a p53-dependent or independent pathway Additionally, epi-sarcotin A and ircinin-1 strongly inhibited the levels of cyclooxygenase (COX)-2 expression without alteration of COX-1. Taken together, the results suggest that the furanoterpenoids from the marine sponge have strong potentials as candidates for anti-cancer drugs.

The Study on Signal to Noise Ratio of Single-Shot Turbo Spin Echo to Reduce Image Distortion in Brain Stem Diffusion MRI (뇌줄기 확산강조 자기공명영상검사 시 뒤틀림을 줄이기 위한 SS-TSE 기법의 신호대잡음비 연구)

  • Koo, Nohyun;Lee, Hobeom;Choi, Kwanwoo;Son, Soonyong;Yoo, Beonggyu
    • Journal of the Korean Society of Radiology
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    • v.10 no.4
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    • pp.241-246
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    • 2016
  • The purpose of this study was to investigate the problems of low signal-to-noise ratio(SNR) of single-shot turbo spin echo(SS-TSE) by quantifying numerically decreased signal to noise ratio. Thirty five patients without brain disease underwent diffusion MRI in 3T scanner from July to October in 2015. Single shot echo planar imaging(SS-EPI) which is conventionally used in MRI was taken to compared SS-TSE in SNR of medulla oblongata. As a result, SNR of SS-TSE diffusion(b0=$314.41{\pm}42.96$, b1000=$117.33{\pm}14.04$) is than SS-EPI diffusion(b0=$514.84{\pm}48.97$, b=$208.65{\pm}25.70$) lower in b=0 image(38.9%) and b=1,000 image(43.8%). Thus, diffusion MR using SS-EPI of MS-EPI should be taken for diagnosis of disease in brain stem due to decreased SNR of diffusion using SS-TSE.

Regulation of Lipoprotein Lipase by Fasting in Epididymal and Mesenteric Adipocytes of Rats

  • Lee, Jae Joon;Chung, Chung Soo;Lee, Myung Yul
    • Asian-Australasian Journal of Animal Sciences
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    • v.21 no.5
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    • pp.715-722
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    • 2008
  • There are marked variations in the activity of lipoprotein lipase (LPL) among adipose depots. The aim of this study was to compare the mechanisms of 24 h of fasting on LPL regulation between epididymal (EPI) adipocytes and mesenteric (MES) adipocytes in rats. 1-Day fasting consistently decreased activities of heparin-releasable LPL, total extractable LPL and cellular LPL markedly in both EPI and MES fat pads. LPL activity in MES fat pads was relatively lower than in the EPI fat pads. Consistent with data on LPL activity, the levels of expression of LPL mRNA in both nutritional states were lower in MES than EPI adipose tissue and isolated adipocytes. The decreased LPL activity after 1 day of fasting in MES adipocytes was explained mainly by a 50% decrease in the relative abundance of LPL mRNA level and a parallel 50% decrease in relative rate of LPL synthesis. In contrast, fasting of 1 day in EPI adipocytes decreased total LPL activity by 47% but did not affect LPL mRNA level or relative rate of LPL synthesis. A decrease in overall protein synthesis contributed to the decreased LPL activity after 1 day fasting both in EPI and MES adipocytes. In MES adipocytes the decrease in LPL activity, LPL mRNA and LPL synthesis were comparable, but in EPI adipocytes the changes in LPL activity were substantially larger than the changes in LPL mRNA level and LPL synthesis. Therefore, fasting decreased fat cell size, LPL activity, LPL mRNA level and relative rate of LPL synthesis in rats, and these effects were more marked in the MES adipocytes. These results clearly demonstrate the regional variations in the metabolic response of adipose tissue and LPL functions to fasting.